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  1. Article ; Online: Renal effects of sodium-glucose co-transporter-2 inhibitors in patients with heart failure with reduced or preserved ejection fraction.

    Patoulias, Dimitrios / Papadopoulos, Christodoulos / Karagiannis, Asterios / Doumas, Michael

    Nefrologia

    2022  

    Language English
    Publishing date 2022-12-06
    Publishing country Spain
    Document type Letter
    ZDB-ID 2837917-2
    ISSN 2013-2514 ; 2013-2514
    ISSN (online) 2013-2514
    ISSN 2013-2514
    DOI 10.1016/j.nefroe.2022.11.021
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Sodium-glucose co-transporter-2 inhibitor mediated cardio-protection: does increase of hematocrit finally matter? Sub-analysis of a prospective, observational study.

    Patoulias, Dimitrios / Papadopoulos, Christodoulos / Karagiannis, Asterios / Doumas, Michael

    Archives of medical sciences. Atherosclerotic diseases

    2022  Volume 7, Page(s) e39–e41

    Language English
    Publishing date 2022-07-07
    Publishing country Poland
    Document type Journal Article
    ISSN 2451-0629
    ISSN 2451-0629
    DOI 10.5114/amsad.2022.116665
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Meta-Analysis Assessing the Impact of Previous Heart Failure and Chronic Kidney Disease on the Cardiovascular Efficacy of Glucagon-Like Peptide-1 Receptor Agonists.

    Patoulias, Dimitrios / Papadopoulos, Christodoulos / Karagiannis, Asterios / Doumas, Michael

    The American journal of cardiology

    2022  Volume 167, Page(s) 165–167

    MeSH term(s) Cardiovascular Diseases/drug therapy ; Cardiovascular Diseases/epidemiology ; Cardiovascular System ; Diabetes Mellitus, Type 2 ; Female ; Glucagon-Like Peptide-1 Receptor/agonists ; Heart Failure/drug therapy ; Humans ; Hypoglycemic Agents/pharmacology ; Male ; Renal Insufficiency, Chronic/complications ; Renal Insufficiency, Chronic/drug therapy
    Chemical Substances Glucagon-Like Peptide-1 Receptor ; Hypoglycemic Agents
    Language English
    Publishing date 2022-01-16
    Publishing country United States
    Document type Letter ; Meta-Analysis
    ZDB-ID 80014-4
    ISSN 1879-1913 ; 0002-9149
    ISSN (online) 1879-1913
    ISSN 0002-9149
    DOI 10.1016/j.amjcard.2021.12.040
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Colchicine for the prevention of COVID-19 "hard" outcomes: All that glitters is not gold.

    Patoulias, Dimitrios / Papadopoulos, Christodoulos / Karagiannis, Asterios / Doumas, Michael

    European journal of internal medicine

    2021  Volume 97, Page(s) 108–109

    MeSH term(s) COVID-19 ; Colchicine/therapeutic use ; Humans ; SARS-CoV-2
    Chemical Substances Colchicine (SML2Y3J35T)
    Language English
    Publishing date 2021-11-25
    Publishing country Netherlands
    Document type Letter ; Comment
    ZDB-ID 1038679-8
    ISSN 1879-0828 ; 0953-6205
    ISSN (online) 1879-0828
    ISSN 0953-6205
    DOI 10.1016/j.ejim.2021.11.016
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Meta-Analysis Evaluating the Cardiovascular Efficacy of Sodium-Glucose Co-Transporter-2 Inhibitors in Patients With Heart Failure With Reduced Ejection Fraction According to Baseline Anemia.

    Patoulias, Dimitrios / Papadopoulos, Christodoulos / Fragakis, Nikolaos / Karagiannis, Asterios / Doumas, Michael

    The American journal of cardiology

    2022  Volume 179, Page(s) 111–114

    MeSH term(s) Anemia ; Diabetes Mellitus, Type 2 ; Glucose ; Heart Failure ; Humans ; Sodium ; Sodium-Glucose Transporter 2 Inhibitors ; Stroke Volume ; Symporters
    Chemical Substances Sodium-Glucose Transporter 2 Inhibitors ; Symporters ; Sodium (9NEZ333N27) ; Glucose (IY9XDZ35W2)
    Language English
    Publishing date 2022-07-22
    Publishing country United States
    Document type Letter ; Meta-Analysis
    ZDB-ID 80014-4
    ISSN 1879-1913 ; 0002-9149
    ISSN (online) 1879-1913
    ISSN 0002-9149
    DOI 10.1016/j.amjcard.2022.06.011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: "Which one should I choose, a glucagon-like peptide-1 receptor agonist or a sodium-glucose cotransporter 2 inhibitor? Or maybe both?"

    Patoulias, Dimitrios / Papadopoulos, Christodoulos / Karagiannis, Asterios / Doumas, Michael

    European journal of internal medicine

    2021  Volume 98, Page(s) 125–127

    MeSH term(s) Glucagon-Like Peptide-1 Receptor/agonists ; Glucose ; Humans ; Hypoglycemic Agents/therapeutic use ; Sodium ; Sodium-Glucose Transporter 2 Inhibitors
    Chemical Substances Glucagon-Like Peptide-1 Receptor ; Hypoglycemic Agents ; Sodium-Glucose Transporter 2 Inhibitors ; Sodium (9NEZ333N27) ; Glucose (IY9XDZ35W2)
    Language English
    Publishing date 2021-12-27
    Publishing country Netherlands
    Document type Letter ; Comment
    ZDB-ID 1038679-8
    ISSN 1879-0828 ; 0953-6205
    ISSN (online) 1879-0828
    ISSN 0953-6205
    DOI 10.1016/j.ejim.2021.12.010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Rosuvastatin and ezetimibe for the treatment of dyslipidemia and hypercholesterolemia.

    Boutari, Chrysoula / Karagiannis, Asterios / Athyros, Vasilios G

    Expert review of cardiovascular therapy

    2021  Volume 19, Issue 7, Page(s) 575–580

    Abstract: ... ...

    Abstract Introduction
    MeSH term(s) Adult ; Anticholesteremic Agents/adverse effects ; Drug Therapy, Combination ; Dyslipidemias/drug therapy ; Ezetimibe/therapeutic use ; Humans ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/adverse effects ; Hypercholesterolemia/drug therapy ; Rosuvastatin Calcium/therapeutic use ; Treatment Outcome
    Chemical Substances Anticholesteremic Agents ; Hydroxymethylglutaryl-CoA Reductase Inhibitors ; Rosuvastatin Calcium (83MVU38M7Q) ; Ezetimibe (EOR26LQQ24)
    Language English
    Publishing date 2021-06-15
    Publishing country England
    Document type Journal Article
    ZDB-ID 2192343-7
    ISSN 1744-8344 ; 1477-9072
    ISSN (online) 1744-8344
    ISSN 1477-9072
    DOI 10.1080/14779072.2021.1940959
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Ertugliflozin + metformin as a treatment option for type 2 diabetes.

    Athyros, Vasilios G / Boutari, Chrysoula / Karagiannis, Asterios

    Expert opinion on pharmacotherapy

    2021  Volume 22, Issue 16, Page(s) 2105–2111

    Abstract: ... ...

    Abstract Introduction
    MeSH term(s) Bridged Bicyclo Compounds, Heterocyclic ; Diabetes Mellitus, Type 2/complications ; Diabetes Mellitus, Type 2/drug therapy ; Humans ; Hypoglycemic Agents/therapeutic use ; Metformin/therapeutic use ; Sodium-Glucose Transporter 2 Inhibitors
    Chemical Substances Bridged Bicyclo Compounds, Heterocyclic ; Hypoglycemic Agents ; Sodium-Glucose Transporter 2 Inhibitors ; ertugliflozin (6C282481IP) ; Metformin (9100L32L2N)
    Language English
    Publishing date 2021-07-15
    Publishing country England
    Document type Journal Article
    ZDB-ID 2001535-5
    ISSN 1744-7666 ; 1465-6566
    ISSN (online) 1744-7666
    ISSN 1465-6566
    DOI 10.1080/14656566.2021.1939676
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Meta-Analysis Assessing the Cardiovascular Efficacy of Sodium-Glucose Co-Transporter-2 Inhibitors in Patients With Chronic Obstructive Pulmonary Disease.

    Patoulias, Dimitrios / Papadopoulos, Christodoulos / Fragakis, Nikolaos / Karagiannis, Asterios / Doumas, Michael

    The American journal of cardiology

    2022  Volume 174, Page(s) 188–189

    MeSH term(s) Cardiovascular Diseases/prevention & control ; Diabetes Mellitus, Type 2 ; Glucose ; Humans ; Hypoglycemic Agents ; Pulmonary Disease, Chronic Obstructive/drug therapy ; Sodium ; Sodium-Glucose Transporter 2 Inhibitors/therapeutic use ; Symporters
    Chemical Substances Hypoglycemic Agents ; Sodium-Glucose Transporter 2 Inhibitors ; Symporters ; Sodium (9NEZ333N27) ; Glucose (IY9XDZ35W2)
    Language English
    Publishing date 2022-05-09
    Publishing country United States
    Document type Letter ; Meta-Analysis
    ZDB-ID 80014-4
    ISSN 1879-1913 ; 0002-9149
    ISSN (online) 1879-1913
    ISSN 0002-9149
    DOI 10.1016/j.amjcard.2022.04.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Cardiovascular Outcomes with Finerenone According to Glycemic Status at Baseline and Prior Treatment with Newer Antidiabetics among Patients with Type 2 Diabetes Mellitus.

    Patoulias, Dimitrios / Papadopoulos, Christodoulos / Karagiannis, Asterios / Vassilikos, Vassilios / Doumas, Michael

    Endocrinology and metabolism (Seoul, Korea)

    2022  Volume 37, Issue 1, Page(s) 170–174

    Abstract: Type 2 diabetes mellitus (T2DM) and cardiovascular disease are closely interconnected. We sought to determine the cardioprotective action of finerenone according to prior treatment with newer antidiabetics and glycemic status. We searched PubMed and ... ...

    Abstract Type 2 diabetes mellitus (T2DM) and cardiovascular disease are closely interconnected. We sought to determine the cardioprotective action of finerenone according to prior treatment with newer antidiabetics and glycemic status. We searched PubMed and Cochrane Library from inception to October 1, 2021 for randomized controlled trials (RCTs) assessing the effect of finerenone on major adverse cardiovascular outcomes in patients with T2DM. We set the primary endpoint as major adverse cardiovascular events (MACE), defined as the composite of death from cardiovascular causes, nonfatal myocardial infarction, nonfatal stroke, or hospitalization for heart failure. We finally included two RCTs in our quantitative synthesis. Compared to placebo, finerenone induced a 23% risk reduction for the composite cardiovascular endpoint, regardless of prior glycemia. We also showed that finerenone provided significant cardiovascular benefit for obese patients with T2DM compared to placebo, although this benefit was diminished for subjects with a body mass index lower than 30 kg/m2. Finally, the combination of finerenone with sodium-glucose co-transporter-2 inhibitors or glucagon-like peptide-1 receptor agonists did not produce a significant risk reduction for MACE. We conclude that finerenone provides significant cardiovascular benefits for patients with T2DM, especially for those who are obese, while glycemic status or treatment with newer antidiabetics at baseline does not affect the observed cardioprotective action.
    MeSH term(s) Diabetes Mellitus, Type 2/complications ; Diabetes Mellitus, Type 2/drug therapy ; Humans ; Hypoglycemic Agents/therapeutic use ; Myocardial Infarction ; Naphthyridines/pharmacology ; Naphthyridines/therapeutic use
    Chemical Substances Hypoglycemic Agents ; Naphthyridines ; finerenone
    Language English
    Publishing date 2022-02-09
    Publishing country Korea (South)
    Document type Journal Article ; Review
    ZDB-ID 2802452-7
    ISSN 2093-5978 ; 2093-5978
    ISSN (online) 2093-5978
    ISSN 2093-5978
    DOI 10.3803/EnM.2021.1296
    Database MEDical Literature Analysis and Retrieval System OnLINE

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