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Article: Authentication of Fennel, Star Anise, and Anise Essential Oils by Gas Chromatography (GC/MS) and Stable Isotope Ratio (GC/IRMS) Analyses.

Murphy, Brett J / Wilson, Tyler M / Ziebarth, Emma A / Bowerbank, Christopher R / Carlson, Richard E

2024 Volume 13, Issue 2

Abstract: The aromatic compound ( ...

Abstract	The aromatic compound (
Language	English
Publishing date	2024-01-12
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2704341-1
ISSN	2223-7747
ISSN	2223-7747
DOI	10.3390/plants13020214
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Double-Reversed Costal Cartilage Graft for Nasal Reconstruction.

Kalmar, Christopher L / Carlson, Anna R / Bartlett, Scott P

Plastic and reconstructive surgery

2023

Abstract: Summary: Costal cartilage provides the ideal graft for reconstruction of the nasal dorsum and tip given its abundant supply and flexural strength. Nevertheless, autologous costal cartilage grafts can be plagued by warping. Several techniques have been ... ...

Abstract	Summary: Costal cartilage provides the ideal graft for reconstruction of the nasal dorsum and tip given its abundant supply and flexural strength. Nevertheless, autologous costal cartilage grafts can be plagued by warping. Several techniques have been devised to offset the intrinsic warping effects of cartilage, but current techniques have several disadvantages. Herein, we present a multimedia demonstration of the double-reversed technique for costal cartilage reconstruction. This strategy is unique in its dual axis of rotation to offset warp in all dimensions. This technique can be performed with conventional instruments, does not introduce foreign material, and provides robust support to counteract the often scarred and contracted soft tissue envelope.
Language	English
Publishing date	2023-05-31
Publishing country	United States
Document type	Journal Article
ZDB-ID	208012-6
ISSN	1529-4242 ; 0032-1052 ; 0096-8501
ISSN (online)	1529-4242
ISSN	0032-1052 ; 0096-8501
DOI	10.1097/PRS.0000000000010776
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Article ; Online: Anomalous sea temperatures can impair coral reef fish recruitment

Shawna A Foo / Rachel R Carlson / Christopher Teague / Gregory P Asner

Environmental Research Letters, Vol 19, Iss 1, p

2024 Volume 014074

Abstract: Understanding how temperature affects coral reef fish recruitment success is crucial for assessing impacts of ocean warming on coral reef resilience. We utilized a long-term fish survey dataset along the west coast of Hawai‘i Island to investigate the ... ...

Abstract	Understanding how temperature affects coral reef fish recruitment success is crucial for assessing impacts of ocean warming on coral reef resilience. We utilized a long-term fish survey dataset along the west coast of Hawai‘i Island to investigate the role of sea surface temperature (SST) in influencing recruitment timing and density. The dataset consisted of 17 years of surveys, with 25 sites annually surveyed in the months of May, July, September and November. We found that peak recruitment, i.e. the maximum number of recruits recorded across all surveys per year, usually occurred during July surveys. For sites where peak recruitment for that year occurred outside July, there were significantly fewer fish recruits than for sites whose peak recruitment occurred in July. In addition, the timing of peak recruitment is influenced by anomalously warm or cool years prior to spawning. The decrease in recruit density outside these times is likely influenced by recruits being exposed to temperatures warmer and cooler than their optimum. Our results show that climate variability is having an impact on the timing of peak recruitment, creating a mismatch between the thermal optimum of developing recruits and the thermal environment they develop in, negatively affecting recruit density in critical coral reef habitats. Altered and reduced recruitment has the potential to disrupt reef community structure and long-term fisheries sustainability in Hawai‘i, with important management implications for coral reefs in the future.
Keywords	coral reef ; recruit fish ; ocean warming ; sea surface temperature ; sea surface temperature anomaly ; Environmental technology. Sanitary engineering ; TD1-1066 ; Environmental sciences ; GE1-350 ; Science ; Q ; Physics ; QC1-999
Subject code	333
Language	English
Publishing date	2024-01-01T00:00:00Z
Publisher	IOP Publishing
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Increased Attack Rates and Decreased Incubation Periods in Raccoons with Chronic Wasting Disease Passaged through Meadow Voles.

Moore, S Jo / Carlson, Christina M / Schneider, Jay R / Johnson, Christopher J / Greenlee, Justin J

Emerging infectious diseases

2022 Volume 28, Issue 4, Page(s) 793–801

Abstract: Chronic wasting disease (CWD) is a naturally-occurring neurodegenerative disease of cervids. Raccoons (Procyon lotor) and meadow voles (Microtus pennsylvanicus) have previously been shown to be susceptible to the CWD agent. To investigate the potential ... ...

Abstract	Chronic wasting disease (CWD) is a naturally-occurring neurodegenerative disease of cervids. Raccoons (Procyon lotor) and meadow voles (Microtus pennsylvanicus) have previously been shown to be susceptible to the CWD agent. To investigate the potential for transmission of the agent of CWD from white-tailed deer to voles and subsequently to raccoons, we intracranially inoculated raccoons with brain homogenate from a CWD-affected white-tailed deer (CWD
MeSH term(s)	Animals ; Arvicolinae ; Deer ; Incidence ; Infectious Disease Incubation Period ; Neurodegenerative Diseases ; Raccoons ; Wasting Disease, Chronic/epidemiology
Language	English
Publishing date	2022-03-23
Publishing country	United States
Document type	Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
ZDB-ID	1380686-5
ISSN	1080-6059 ; 1080-6040
ISSN (online)	1080-6059
ISSN	1080-6040
DOI	10.3201/eid2804.210271
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Article: Reconstitution of the SARS-CoV-2 ribonucleosome provides insights into genomic RNA packaging and regulation by phosphorylation.

Carlson, Christopher R / Adly, Armin N / Bi, Maxine / Cheng, Yifan / Morgan, David O

bioRxiv : the preprint server for biology

2022

Abstract: The nucleocapsid (N) protein of coronaviruses is responsible for compaction of the ∼30-kb RNA genome in the ∼100-nm virion. Cryo-electron tomography suggests that each virion contains 35-40 viral ribonucleoprotein (vRNP) complexes, or ribonucleosomes, ... ...

Abstract	The nucleocapsid (N) protein of coronaviruses is responsible for compaction of the ∼30-kb RNA genome in the ∼100-nm virion. Cryo-electron tomography suggests that each virion contains 35-40 viral ribonucleoprotein (vRNP) complexes, or ribonucleosomes, arrayed along the genome. There is, however, little mechanistic understanding of the vRNP complex. Here, we show that N protein, when combined with viral RNA fragments in vitro, forms cylindrical 15-nm particles similar to the vRNP structures observed within coronavirus virions. These vRNPs form in the presence of stem-loop-containing RNA and depend on regions of N protein that promote protein-RNA and protein-protein interactions. Phosphorylation of N protein in its disordered serine/arginine (SR) region weakens these interactions and disrupts vRNP assembly. We propose that unmodified N binds stem-loop-rich regions in genomic RNA to form compact vRNP complexes within the nucleocapsid, while phosphorylated N maintains uncompacted viral RNA to promote the protein's transcriptional function.
Language	English
Publishing date	2022-05-24
Publishing country	United States
Document type	Preprint
DOI	10.1101/2022.05.23.493138
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Article ; Online: Assembly of SARS-CoV-2 ribonucleosomes by truncated N

Adly, Armin N / Bi, Maxine / Carlson, Christopher R / Syed, Abdullah M / Ciling, Alison / Doudna, Jennifer A / Cheng, Yifan / Morgan, David O

The Journal of biological chemistry

2023 Volume 299, Issue 12, Page(s) 105362

Abstract: The nucleocapsid (N) protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) compacts the RNA genome into viral ribonucleoprotein (vRNP) complexes within virions. Assembly of vRNPs is inhibited by phosphorylation of the N protein serine/ ... ...

Abstract	The nucleocapsid (N) protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) compacts the RNA genome into viral ribonucleoprotein (vRNP) complexes within virions. Assembly of vRNPs is inhibited by phosphorylation of the N protein serine/arginine (SR) region. Several SARS-CoV-2 variants of concern carry N protein mutations that reduce phosphorylation and enhance the efficiency of viral packaging. Variants of the dominant B.1.1 viral lineage also encode a truncated N protein, termed N
MeSH term(s)	Humans ; COVID-19/virology ; Nucleocapsid Proteins/genetics ; Nucleocapsid Proteins/metabolism ; Nucleocapsid Proteins/ultrastructure ; RNA, Viral/metabolism ; RNA, Viral/ultrastructure ; SARS-CoV-2/genetics ; SARS-CoV-2/metabolism ; SARS-CoV-2/ultrastructure ; Phosphorylation ; Virus Assembly/genetics
Chemical Substances	Nucleocapsid Proteins ; RNA, Viral ; nucleocapsid phosphoprotein, SARS-CoV-2
Language	English
Publishing date	2023-10-19
Publishing country	United States
Document type	Journal Article
ZDB-ID	2997-x
ISSN	1083-351X ; 0021-9258
ISSN (online)	1083-351X
ISSN	0021-9258
DOI	10.1016/j.jbc.2023.105362
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Article ; Online: Dural venous sinus stenting technique for idiopathic intracranial hypertension in patients with tortuous venous anatomy.

Gorjian, Mehrnoush / Andrada, Jason E / Sitko, Kevin R / Sorte, Danielle E / Taylor, Christopher L / Eliyas, Javed Khader / Carlson, Andrew P

Neurosurgical review

2023 Volume 46, Issue 1, Page(s) 177

Abstract: Venous sinus stenting (VSS) for medically refractory idiopathic intracranial hypertension (IIH) is emerging as a safe and effective alternative to shunting. However, stent navigation past the jugular bulb with commonly used carotid stenting systems via ... ...

Abstract	Venous sinus stenting (VSS) for medically refractory idiopathic intracranial hypertension (IIH) is emerging as a safe and effective alternative to shunting. However, stent navigation past the jugular bulb with commonly used carotid stenting systems via femoral access in cases with tortuous venous anatomy can present a challenge, leading to procedural failure. We present a technical refinement using a cervical access and peripheral vascular stent with a more stable 0.035-in. delivery platform as an alternative to the traditional approach to simplify the procedure and overcome the technical difficulties in cases with tortuous venous anatomy. Our institutional database for patients who had IIH and undergone VSS using the peripheral vascular stent between 2013 and 2023 was retrospectively reviewed. Data on 36 patients (33 women, 3 men, mean age 32 years) was collected. VSS was technically successful in all patients (100%) without major complications or thrombosis. There was one case of minor neck cellulitis treated with oral antibiotics. Three patients underwent repeat stenting, and 2 patients had ventriculoperitoneal shunt placement after stenting due to persistent or recurrent symptoms. All patients (100%) had improvement or resolution of papilledema; however, six patients had evidence of optic atrophy and persistent vision loss. Headache was resolved or improved in 91% of patients. In the presence of tortuous venous anatomy, VSS using cervical access and a peripheral vascular stent with a more stable 0.035-in. delivery platform can be considered as a safe and effective alternative approach with shorter procedure time. This approach is particularly advantageous in situations where the procedure is prolonged or high dose of contrast has been administered due to the technical challenges associated with the traditional use of carotid systems via femoral access for stent delivery.
MeSH term(s)	Male ; Humans ; Female ; Adult ; Pseudotumor Cerebri/complications ; Retrospective Studies ; Cranial Sinuses/surgery ; Neurosurgical Procedures ; Stents/adverse effects ; Intracranial Hypertension/etiology
Language	English
Publishing date	2023-07-18
Publishing country	Germany
Document type	Journal Article
ZDB-ID	6907-3
ISSN	1437-2320 ; 0344-5607
ISSN (online)	1437-2320
ISSN	0344-5607
DOI	10.1007/s10143-023-02087-0
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Article ; Online: Multisite phosphorylation by Cdk1 initiates delayed negative feedback to control mitotic transcription.

Asfaha, Jonathan B / Örd, Mihkel / Carlson, Christopher R / Faustova, Ilona / Loog, Mart / Morgan, David O

Current biology : CB

2021 Volume 32, Issue 1, Page(s) 256–263.e4

Abstract: Cell-cycle progression is driven by the phosphorylation of cyclin-dependent kinase (Cdk) substrates. ...

Abstract	Cell-cycle progression is driven by the phosphorylation of cyclin-dependent kinase (Cdk) substrates.
MeSH term(s)	CDC2 Protein Kinase/genetics ; CDC2 Protein Kinase/metabolism ; Cell Cycle Proteins/metabolism ; Cyclin B/genetics ; Cyclin B/metabolism ; Cyclins/genetics ; Feedback ; Mitosis ; Phosphorylation ; Saccharomyces cerevisiae/metabolism ; Saccharomyces cerevisiae Proteins/genetics ; Saccharomyces cerevisiae Proteins/metabolism ; Transcription Factors/metabolism
Chemical Substances	Cell Cycle Proteins ; Cyclin B ; Cyclins ; Saccharomyces cerevisiae Proteins ; Transcription Factors ; CDC2 Protein Kinase (EC 2.7.11.22)
Language	English
Publishing date	2021-11-23
Publishing country	England
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ZDB-ID	1071731-6
ISSN	1879-0445 ; 0960-9822
ISSN (online)	1879-0445
ISSN	0960-9822
DOI	10.1016/j.cub.2021.11.001
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Article ; Online: Endoscope-Assisted Fronto-Orbital Distraction Osteogenesis.

Kalmar, Christopher L / Carlson, Anna R / Kosyk, Mychajlo S / Zapatero, Zachary D / Heuer, Gregory G / Taylor, Jesse A

Plastic and reconstructive surgery

2022 Volume 150, Issue 1, Page(s) 157–161

Abstract: Summary: Anterior cranial vault fronto-orbital distraction osteogenesis is a promising treatment modality for children with unicoronal craniosynostosis. A minimally invasive, endoscope-assisted approach offers the additional potential benefits of less ... ...

Abstract	Summary: Anterior cranial vault fronto-orbital distraction osteogenesis is a promising treatment modality for children with unicoronal craniosynostosis. A minimally invasive, endoscope-assisted approach offers the additional potential benefits of less scalp scarring, decreased blood loss, and decreased scalp dissection. In this article, the authors present a novel technique for minimally invasive, endoscope-assisted fronto-orbital distraction osteogenesis.
MeSH term(s)	Child ; Craniosynostoses/surgery ; Endoscopes ; Humans ; Infant ; Osteogenesis, Distraction/methods ; Skull/surgery
Language	English
Publishing date	2022-05-17
Publishing country	United States
Document type	Journal Article
ZDB-ID	208012-6
ISSN	1529-4242 ; 0032-1052 ; 0096-8501
ISSN (online)	1529-4242
ISSN	0032-1052 ; 0096-8501
DOI	10.1097/PRS.0000000000009256
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Article: Sphenoid Wing Dysplasia in the Absence of Neurofibromatosis: Diagnosis and Management of a Novel Phenotype.

Zapatero, Zachary D / Kalmar, Christopher L / Kosyk, Mychajlo S / Carlson, Anna R / Bartlett, Scott P

Plastic and reconstructive surgery. Global open

2021 Volume 9, Issue 3, Page(s) e3483

Abstract: Congenital sphenoid wing dysplasia is one of the major diagnostic criteria for neurofibromatosis type 1, and is often considered pathognomonic for the disease. Between 5% and 12% of neurofibromatosis type 1 cases have evidence of sphenoid wing dysplasia. ...

Abstract	Congenital sphenoid wing dysplasia is one of the major diagnostic criteria for neurofibromatosis type 1, and is often considered pathognomonic for the disease. Between 5% and 12% of neurofibromatosis type 1 cases have evidence of sphenoid wing dysplasia. Sequelae of this deficiency include slow expansion of the middle temporal fossa and progressive herniation of the temporal lobe into the orbital cavity, resulting in pulsatile exophthalmos. Herein, we report a patient with greater sphenoid wing agenesis and middle temporal fossa enlargement requiring transcranial orbital reconstruction in the absence of neurofibromatosis. To our knowledge, this represents a novel craniofacial phenotype of sphenoid wing agenesis in the absence of neurofibromatosis previously not described in the literature.
Language	English
Publishing date	2021-03-18
Publishing country	United States
Document type	Case Reports
ZDB-ID	2851682-5
ISSN	2169-7574 ; 2169-7574
ISSN (online)	2169-7574
ISSN	2169-7574
DOI	10.1097/GOX.0000000000003483
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