Article ; Online: Skin wound healing in diabetic rat model using low-dose photodynamic therapy.
Biotechnology and applied biochemistry
2024
Abstract: Chronic wound is one of the major challenges in medicine and imposes a heavy financial burden on the healthcare of different countries. Diabetic foot ulcers as one of the important examples for chronic wounds can lead to lower limb amputation, disability, ...
Abstract | Chronic wound is one of the major challenges in medicine and imposes a heavy financial burden on the healthcare of different countries. Diabetic foot ulcers as one of the important examples for chronic wounds can lead to lower limb amputation, disability, and death in diabetics. In this regard, novel technology with low side effects got attention in recent years. Low-dose photodynamic therapy (LDPDT) is one of the noninvasive techniques that can be considered for wound healing in diabetic wounds. In this experiment, we aim to study the effect of LDPDT on diabetic rats' wound healing and compare it to healthy rats. In this in vitro experimental study, 32 male rats were used. Rats in both normal and diabetic (streptozotocin injection) groups after being wounded (two wounds [0.8 × 0.8 cm]) on the back of each rat were randomly divided into four groups, including the control group (without treatment), radiation-only (660 nm |
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Language | English |
Publishing date | 2024-02-26 |
Publishing country | United States |
Document type | Journal Article |
ZDB-ID | 883433-7 |
ISSN | 1470-8744 ; 0885-4513 |
ISSN (online) | 1470-8744 |
ISSN | 0885-4513 |
DOI | 10.1002/bab.2568 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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