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  1. Article ; Online: Partner incarceration, maternal substance use, and the mediating role of social support: A longitudinal analysis using the future of families and child wellbeing study.

    Marziali, Megan E / Prins, Seth J / Gutkind, Sarah / Martins, Silvia S

    Social science & medicine (1982)

    2024  Volume 349, Page(s) 116896

    Abstract: Introduction: The United States is responsible for the highest incarceration rate globally. This study aimed to explore the impact of partner incarceration on maternal substance use and whether social support mediates the relationship between partner ... ...

    Abstract Introduction: The United States is responsible for the highest incarceration rate globally. This study aimed to explore the impact of partner incarceration on maternal substance use and whether social support mediates the relationship between partner incarceration and maternal substance use.
    Methods: Using data from the Future of Families and Child Wellbeing Study, a longitudinal cohort following new parents and children, this analysis quantifies the relationship between paternal incarceration and maternal substance use (N = 2823). We analyzed maternal responses in years 3 (2001-2003), 5 (2003-2006), 9 (2007-2010), and 15 (2014-2017). We explored the role of financial support and emergency social support as potential mediators. Confirmatory factor analysis (CFA) was employed to construct support-related mediators. We modeled the impact of partner incarceration and maternal substance use using generalized estimating equations (GEE) to account for repeated measures, adjusting for appropriate confounders (age of mother at child's birth, race, education, employment, and history of intimate partner violence).
    Results: Nearly half (44.2%, N = 1247) of participants reported partner incarceration. Among mothers who experienced partner incarceration, the odds of reporting substance use were 110% greater than those who reported no partner incarceration (adjusted Odds Ratio [aOR]: 2.10; 95% Confidence Interval (CI):1.67-2.63). Financial support at year 5 accounted for 19.5% (95% CI: 6.03-33.06%) of the association between partner incarceration at year 3 and substance use at year 9; emergency social support at year 5 accounted for 6.4% (95% CI: 0.51-12.25%) of the association between partner incarceration and substance use at year 9. Neither financial nor emergency social support at year 9 were significant mediators between partner incarceration at year 3 and substance use at year 15.
    Conclusions: These findings demonstrate that partner incarceration impacts maternal substance use. Financial and emergency support may partially mediate this relationship in the short term, which has important implications for families disrupted by mass incarceration.
    Language English
    Publishing date 2024-04-17
    Publishing country England
    Document type Journal Article
    ZDB-ID 4766-1
    ISSN 1873-5347 ; 0037-7856 ; 0277-9536
    ISSN (online) 1873-5347
    ISSN 0037-7856 ; 0277-9536
    DOI 10.1016/j.socscimed.2024.116896
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Response to McIlveen et al.: Collaboration and transparency are necessary to effectively estimate substance use disorder treatment need.

    Nesoff, Elizabeth D / Marziali, Megan E / Martins, Silvia S

    Addiction (Abingdon, England)

    2022  Volume 117, Issue 8, Page(s) 2361–2362

    MeSH term(s) Buprenorphine ; Humans ; Opioid-Related Disorders
    Chemical Substances Buprenorphine (40D3SCR4GZ)
    Language English
    Publishing date 2022-05-05
    Publishing country England
    Document type Letter ; Research Support, N.I.H., Extramural ; Comment
    ZDB-ID 1141051-6
    ISSN 1360-0443 ; 0965-2140
    ISSN (online) 1360-0443
    ISSN 0965-2140
    DOI 10.1111/add.15909
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Perceptions of peer and parental attitudes toward substance use and actual adolescent substance use: The impact of adolescent-confidant relationships.

    Marziali, Megan E / Levy, Natalie S / Martins, Silvia S

    Substance abuse

    2022  Volume 43, Issue 1, Page(s) 1085–1093

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Adolescent ; Adolescent Behavior ; Attitude ; Humans ; Marijuana Use/epidemiology ; Parents ; Peer Group ; Substance-Related Disorders/epidemiology
    Language English
    Publishing date 2022-04-20
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 1458030-5
    ISSN 1547-0164 ; 0889-7077
    ISSN (online) 1547-0164
    ISSN 0889-7077
    DOI 10.1080/08897077.2022.2060439
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Development and design of a mobile application for prescription opioid clinical decision-making: a feasibility study in New York City, USA.

    Marziali, Megan E / Giordano, Mirna / Gleit, Zachary / Prigoff, Jake / Landau, Ruth / Martins, Silvia S

    BMJ open

    2023  Volume 13, Issue 2, Page(s) e066427

    Abstract: Objectives: Excessive opioid prescribing is a contributing factor to the opioid epidemic in the USA. We aimed to develop, implement and evaluate the usability of a clinical decision-making mobile application (app) for opioid prescription after surgery.!# ...

    Abstract Objectives: Excessive opioid prescribing is a contributing factor to the opioid epidemic in the USA. We aimed to develop, implement and evaluate the usability of a clinical decision-making mobile application (app) for opioid prescription after surgery.
    Methods: We developed two clinical decision trees, one for opioid prescription after adult laparoscopic cholecystectomy and one for posterior spinal fusion surgery in adolescents. We developed a mobile app incorporating the two algorithms with embedded clinical decision-making, which was tested by opioid prescribers. A survey collected prescription intention prior to app use and participants' evaluation. Participants included opioid prescribers for patients undergoing (1) laparoscopic cholecystectomy in adults or (2) posterior spinal fusion in adolescents with idiopathic scoliosis.
    Results: Eighteen healthcare providers were included in this study (General Surgery: 8, Paediatrics: 10). Intended opioid prescription before app use varied between departments (General Surgery: 0-10 pills (mean=5.9); Paediatrics: 6-30 pills (mean=20.8)). Intention to continue using the app after using the app multiple times varied between departments (General Surgery: N=3/8; Paediatrics: N=7/10). The most reported reason for not using the app is lack of time.
    Conclusions: In this project evaluating the development and implementation of an app for opioid prescription after two common surgeries with different prescription patterns, the surgical procedure with higher intended and variable opioid prescription (adolescent posterior spinal fusion surgery) was associated with participants more willing to use the app. Future iterations of this opioid prescribing intervention should target surgical procedures with high variability in both patients' opioid use and providers' prescription patterns.
    MeSH term(s) Adolescent ; Adult ; Humans ; Child ; Analgesics, Opioid/therapeutic use ; Feasibility Studies ; New York City ; Mobile Applications ; Practice Patterns, Physicians' ; Clinical Decision-Making ; Prescriptions
    Chemical Substances Analgesics, Opioid
    Language English
    Publishing date 2023-02-28
    Publishing country England
    Document type Journal Article ; Research Support, U.S. Gov't, P.H.S. ; Research Support, N.I.H., Extramural
    ZDB-ID 2599832-8
    ISSN 2044-6055 ; 2044-6055
    ISSN (online) 2044-6055
    ISSN 2044-6055
    DOI 10.1136/bmjopen-2022-066427
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: The estimated impact of state-level support for expanded delivery of substance use disorder treatment during the COVID-19 pandemic.

    Nesoff, Elizabeth D / Marziali, Megan E / Martins, Silvia S

    Addiction (Abingdon, England)

    2021  Volume 117, Issue 6, Page(s) 1781–1786

    Abstract: Background and aims: To prevent COVID-19 transmission, some United States (US) federal regulations on substance use disorder (SUD) treatment were suspended in March 2020. This study aimed to quantify the extent of state-level policy uptake and the ... ...

    Abstract Background and aims: To prevent COVID-19 transmission, some United States (US) federal regulations on substance use disorder (SUD) treatment were suspended in March 2020. This study aimed to quantify the extent of state-level policy uptake and the potential number of people with SUD affected by these policy changes across the US, as well as to assess if policy uptake correlated with rates of people with SUD already in treatment or needing treatment.
    Design: Cross-sectional analysis of policies implemented as of April 13, 2020.
    Setting and participants: A total of 50 US states and the District of Columbia MEASUREMENTS: State-level implementation of: oral schedule II controlled substances emergency prescription, extended take-home doses for medication for opioid use disorders (MOUD), home-delivery of take-home medications, telemedicine for schedule II-IV prescriptions, telemedicine for buprenorphine prescribing initiation, and waiver of out-of-state Drug Enforcement Administration (DEA) registration. Rates per 100 000 population of: adults in treatment for SUD, MOUD treatment at facilities with opioid treatment programs, SUD based on Diagnostic and Statistical Manual of Mental Disorders (DSM)-IV criteria, and needing, but not receiving treatment.
    Findings: Half of the states (n = 24) enacted no policies, leaving ~460 955 people in treatment and 114 370 people on MOUD pre-pandemic uncovered by any policy expansion. Only telemedicine for buprenorphine initiation was marginally associated with pre-pandemic rate of SUD treatment (OR = 1.003, 95% CI = [1.001, 1.006]) and rate of MOUD therapy (OR = 1.006, 95% CI = [1.002, 1.011]) in univariable analysis, but these associations were no longer significant when controlling for state-level demographics. No policies were associated with state-wide SUD prevalence or rate of unmet treatment need (P > 0.05).
    Conclusions: Twenty-four United States states did not implement at least one federal policy for substance use disorder treatment expansion as of April 2020, leaving approximately half a million people in treatment pre-pandemic potentially without access to treatment or risking exposure to COVID-19 to continue in-person therapies.
    MeSH term(s) Buprenorphine/therapeutic use ; COVID-19 ; Cross-Sectional Studies ; Humans ; Opiate Substitution Treatment ; Opioid-Related Disorders/drug therapy ; Opioid-Related Disorders/epidemiology ; Pandemics ; Pharmaceutical Preparations ; United States
    Chemical Substances Pharmaceutical Preparations ; Buprenorphine (40D3SCR4GZ)
    Language English
    Publishing date 2021-12-27
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 1141051-6
    ISSN 1360-0443 ; 0965-2140
    ISSN (online) 1360-0443
    ISSN 0965-2140
    DOI 10.1111/add.15778
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Development and design of a mobile application for prescription opioid clinical decision-making

    Ruth Landau / Megan E Marziali / Silvia S Martins / Mirna Giordano / Zachary Gleit / Jake Prigoff

    BMJ Open, Vol 13, Iss

    a feasibility study in New York City, USA

    2023  Volume 2

    Abstract: Objectives Excessive opioid prescribing is a contributing factor to the opioid epidemic in the USA. We aimed to develop, implement and evaluate the usability of a clinical decision-making mobile application (app) for opioid prescription after surgery ... ...

    Abstract Objectives Excessive opioid prescribing is a contributing factor to the opioid epidemic in the USA. We aimed to develop, implement and evaluate the usability of a clinical decision-making mobile application (app) for opioid prescription after surgery.Methods We developed two clinical decision trees, one for opioid prescription after adult laparoscopic cholecystectomy and one for posterior spinal fusion surgery in adolescents. We developed a mobile app incorporating the two algorithms with embedded clinical decision-making, which was tested by opioid prescribers. A survey collected prescription intention prior to app use and participants’ evaluation. Participants included opioid prescribers for patients undergoing (1) laparoscopic cholecystectomy in adults or (2) posterior spinal fusion in adolescents with idiopathic scoliosis.Results Eighteen healthcare providers were included in this study (General Surgery: 8, Paediatrics: 10). Intended opioid prescription before app use varied between departments (General Surgery: 0–10 pills (mean=5.9); Paediatrics: 6–30 pills (mean=20.8)). Intention to continue using the app after using the app multiple times varied between departments (General Surgery: N=3/8; Paediatrics: N=7/10). The most reported reason for not using the app is lack of time.Conclusions In this project evaluating the development and implementation of an app for opioid prescription after two common surgeries with different prescription patterns, the surgical procedure with higher intended and variable opioid prescription (adolescent posterior spinal fusion surgery) was associated with participants more willing to use the app. Future iterations of this opioid prescribing intervention should target surgical procedures with high variability in both patients’ opioid use and providers’ prescription patterns.
    Keywords Medicine ; R
    Subject code 616
    Language English
    Publishing date 2023-02-01T00:00:00Z
    Publisher BMJ Publishing Group
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Predictors of COVID-19 testing rates: A cross-country comparison.

    Marziali, Megan E / Hogg, Robert S / Oduwole, Oluwamayowa A / Card, Kiffer G

    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases

    2021  Volume 104, Page(s) 370–372

    Abstract: Objectives: Cross-country comparisons of coronavirus disease (COVID-19) have largely been applied to mortality analyses. The goal of this analysis is to explore predictors of COVID-19 testing through cross-country comparisons, to better inform ... ...

    Abstract Objectives: Cross-country comparisons of coronavirus disease (COVID-19) have largely been applied to mortality analyses. The goal of this analysis is to explore predictors of COVID-19 testing through cross-country comparisons, to better inform international health policies.
    Methods: Testing and case-based data were amassed from Our World in Data, and information regarding predictors was gathered from the World Bank. We investigate Human Development Index (HDI), health expenditure, universal health coverage (UHC), urban population, service industry workers (%), and air pollution as predictors. We explored testing data through July 31, 2020, or most recently available, using case-indexing methods, which involve synchronizing countries by date of first reported COVID-19 case as an index date and normalizing to the cumulative tests 25 days post-index date. Three multivariable linear regression models were built in a stepwise fashion to explore the association between the indexed number of COVID-19 tests and HDI scores.
    Results: A total of 86 countries were included in the final analytical sample, excluding countries with missing data. HDI and urban population were found to be significantly associated with testing levels.
    Conclusions: Results suggest that social conditions and government capacity remain consistently salient in the consideration of testing rates. International efforts to assist low-HDI countries are needed to support the global COVID-19 response.
    MeSH term(s) COVID-19/diagnosis ; COVID-19/economics ; COVID-19/virology ; COVID-19 Testing/statistics & numerical data ; Global Health ; Health Expenditures ; Health Policy ; Humans ; Linear Models ; SARS-CoV-2/isolation & purification ; Universal Health Insurance
    Language English
    Publishing date 2021-01-09
    Publishing country Canada
    Document type Comparative Study ; Journal Article
    ZDB-ID 1331197-9
    ISSN 1878-3511 ; 1201-9712
    ISSN (online) 1878-3511
    ISSN 1201-9712
    DOI 10.1016/j.ijid.2020.12.083
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Investigating the effect of national government physical distancing measures on depression and anxiety during the COVID-19 pandemic through meta-analysis and meta-regression.

    Castaldelli-Maia, João M / Marziali, Megan E / Lu, Ziyin / Martins, Silvia S

    Psychological medicine

    2021  Volume 51, Issue 6, Page(s) 881–893

    Abstract: ... the implementation of mitigation strategies (i.e. public transportation closures, stay-at-home orders, etc.) impacted ... i.e. city-specific) contexts.: Conclusions and implications of key findings: Mental health concerns ...

    Abstract Background: COVID-19 physical distancing measures can potentially increase the likelihood of mental disorders. It is unknown whether these measures are associated with depression and anxiety.
    Objectives: To investigate meta-analytic global levels of depression and anxiety during the COVID-19 pandemic and how the implementation of mitigation strategies (i.e. public transportation closures, stay-at-home orders, etc.) impacted such disorders.
    Data sources: PubMed, MEDLINE, Web of Science, BIOSIS Citation Index, Current Content Connect, PsycINFO, CINAHL, medRxiv, and PsyArXiv databases for depression and anxiety prevalences; Oxford Covid-19 Government Response Tracker for the containment and closure policies indexes; Global Burden of Disease Study for previous levels of depression and anxiety.
    Study eligibility criteria: Original studies conducted during COVID-19 pandemic, which assessed categorical depression and anxiety, using PHQ-9 and GAD-7 scales (cutoff ⩾10).
    Participants and interventions: General population, healthcare providers, students, and patients. National physical distancing measures.
    Study appraisal and synthesis methods: Meta-analysis and meta-regression.
    Results: In total, 226 638 individuals were assessed within the 60 included studies. Global prevalence of both depression and anxiety during the COVID-19 pandemic was 24.0% and 21.3%, respectively. There were differences in the prevalence of both anxiety and depression reported across regions and countries. Asia (17.6% and 17.9%), and China (16.2% and 15.5%) especially, had the lowest prevalence of both disorders. Regarding the impact of mitigation strategies on mental health, only public transportation closures increased the prevalence of anxiety, especially in Europe.
    Limitations: Country-level data on physical distancing measures and previous anxiety/depression may not necessarily reflect local (i.e. city-specific) contexts.
    Conclusions and implications of key findings: Mental health concerns should not be viewed only as a delayed consequence of the COVID-19 pandemic, but also as a concurrent epidemic. Our data provide support for policy-makers to consider real-time enhanced mental health services, and increase initiatives to foster positive mental health outcomes.
    MeSH term(s) Anxiety/epidemiology ; Asia/epidemiology ; COVID-19 ; China/epidemiology ; Depression/epidemiology ; Europe/epidemiology ; Federal Government ; Female ; Humans ; Male ; Mental Health ; Physical Distancing ; Prevalence ; SARS-CoV-2
    Language English
    Publishing date 2021-03-02
    Publishing country England
    Document type Journal Article ; Meta-Analysis ; Research Support, N.I.H., Extramural
    ZDB-ID 217420-0
    ISSN 1469-8978 ; 0033-2917
    ISSN (online) 1469-8978
    ISSN 0033-2917
    DOI 10.1017/S0033291721000933
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Physical Distancing in COVID-19 May Exacerbate Experiences of Social Isolation among People Living with HIV.

    Marziali, Megan E / Card, Kiffer G / McLinden, Taylor / Wang, Lu / Trigg, Jason / Hogg, Robert S

    AIDS and behavior

    2020  Volume 24, Issue 8, Page(s) 2250–2252

    MeSH term(s) Anti-HIV Agents/therapeutic use ; Betacoronavirus ; COVID-19 ; Coronavirus Infections/epidemiology ; Coronavirus Infections/prevention & control ; HIV Infections/drug therapy ; HIV Infections/psychology ; Humans ; Pandemics ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/prevention & control ; Quarantine/methods ; Quarantine/psychology ; SARS-CoV-2 ; Social Isolation/psychology
    Chemical Substances Anti-HIV Agents
    Keywords covid19
    Language English
    Publishing date 2020-04-23
    Publishing country United States
    Document type Editorial
    ZDB-ID 1339885-4
    ISSN 1573-3254 ; 1090-7165
    ISSN (online) 1573-3254
    ISSN 1090-7165
    DOI 10.1007/s10461-020-02872-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Corrigendum: Substance Use in Mild-COVID-19 Patients: A Retrospective Study.

    Ismael, Flavia / Zaramella, Beatriz / Battagin, Tatiane / Bizario, João C S / Gallego, Júlia / Villela, Victoria / de Queiroz, Lilian Bezerra / Leal, Fabio E / Torales, Julio / Ventriglio, Antonio / Marziali, Megan E / Gonçalves, Priscila D / Martins, Silvia S / Castaldelli-Maia, João M

    Frontiers in public health

    2021  Volume 9, Page(s) 703562

    Abstract: This corrects the article DOI: 10.3389/fpubh.2021.634396.]. ...

    Abstract [This corrects the article DOI: 10.3389/fpubh.2021.634396.].
    Language English
    Publishing date 2021-06-16
    Publishing country Switzerland
    Document type Published Erratum
    ZDB-ID 2711781-9
    ISSN 2296-2565 ; 2296-2565
    ISSN (online) 2296-2565
    ISSN 2296-2565
    DOI 10.3389/fpubh.2021.703562
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