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  1. Article ; Online: SPECTRa-T: machine-based data extraction and semantic searching of chemistry e-theses.

    Downing, Jim / Harvey, Matt J / Morgan, Peter B / Murray-Rust, Peter / Rzepa, Henry S / Stewart, Diana C / Tonge, Alan P / Townsend, Joe A

    Journal of chemical information and modeling

    2010  Volume 50, Issue 2, Page(s) 251–261

    Abstract: The SPECTRa-T project has developed text-mining tools to extract named chemical entities (NCEs ... such as chemical names and terms, and chemical objects (COs), e.g., experimental spectral assignments and ... physical chemistry properties, from electronic theses (e-theses). Although NCEs were readily identified ...

    Abstract The SPECTRa-T project has developed text-mining tools to extract named chemical entities (NCEs), such as chemical names and terms, and chemical objects (COs), e.g., experimental spectral assignments and physical chemistry properties, from electronic theses (e-theses). Although NCEs were readily identified within the two major document formats studied, only the use of structured documents enabled identification of chemical objects and their association with the relevant chemical entity (e.g., systematic chemical name). A corpus of theses was analyzed and it is shown that a high degree of semantic information can be extracted from structured documents. This integrated information has been deposited in a persistent Resource Description Framework (RDF) triple-store that allows users to conduct semantic searches. The strength and weaknesses of several document formats are reviewed.
    MeSH term(s) Academic Dissertations as Topic ; Automatic Data Processing ; Chemistry/education ; Data Mining/methods ; Databases, Factual ; False Positive Reactions ; Software
    Language English
    Publishing date 2010-02-22
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 190019-5
    ISSN 1549-960X ; 0095-2338
    ISSN (online) 1549-960X
    ISSN 0095-2338
    DOI 10.1021/ci9003688
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Successful haploidentical mismatched bone marrow transplantation in severe combined immunodeficiency: T cell removal using CAMPATH-I monoclonal antibody and E-rosetting.

    Morgan, G / Linch, D C / Knott, L T / Davies, E G / Sieff, C / Chessells, J M / Hale, G / Waldmann, H / Levinsky, R J

    British journal of haematology

    1986  Volume 62, Issue 3, Page(s) 421–430

    Abstract: ... from their HLA haploidentical parents. T-lymphocytes were removed by complement mediated lysis ...

    Abstract Six patients with severe combined immunodeficiency were transplanted with bone marrow from their HLA haploidentical parents. T-lymphocytes were removed by complement mediated lysis with a monoclonal antibody (CAMPATH-I) followed by rosetting with sheep erythrocytes. The patients were pre-conditioned with marrow ablative chemotherapy, using busulphan and cyclophosphamide. There was graft take in five patients, with evidence of transient acute graft-versus-host disease only. Three patients are alive and well greater than 5 months after transplant, and one who is 12 months post graft has full reconstitution of cell mediated and humoral immunity, including specific antibody response to immunization. Transplantation across major histocompatibility barriers can be successfully achieved using this method of treatment of donor marrow.
    MeSH term(s) Antibodies, Monoclonal ; Antigens ; Bone Marrow Transplantation ; Cell Separation ; Child, Preschool ; Female ; Humans ; Immunologic Deficiency Syndromes/immunology ; Immunologic Deficiency Syndromes/therapy ; Infant ; Male ; Rosette Formation ; T-Lymphocytes
    Chemical Substances Antibodies, Monoclonal ; Antigens
    Language English
    Publishing date 1986-03
    Publishing country England
    Document type Case Reports ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 80077-6
    ISSN 1365-2141 ; 0007-1048
    ISSN (online) 1365-2141
    ISSN 0007-1048
    DOI 10.1111/j.1365-2141.1986.tb02953.x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book ; Online ; E-Book: Pathology of the placenta

    Khong, T. Yee / Mooney, Eoghan E. / Nikkels, Peter G. J. / Morgan, Terry K. / Gordijn, Sanne J.

    a practical guide

    2019  

    Author's details T. Yee Khong, Eoghan E. Mooney, Peter G. J. Nikkels, Terry K. Morgan, Sanne J. Gordijn editors
    Keywords Pathology ; Obstetrics ; Epidemiology ; Pediatrics
    Subject code 616.07
    Language English
    Size 1 Online-Ressource (XVI, 395 Seiten), Illustrationen
    Publisher Springer International Publishing
    Publishing place Cham
    Publishing country Switzerland
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT021323381
    ISBN 978-3-319-97214-5 ; 9783319972138 ; 3-319-97214-6 ; 3319972138
    DOI 10.1007/978-3-319-97214-5
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  4. Article: Letter: Death after E.C.T.

    Morgan, A A

    British medical journal

    1974  Volume 3, Issue 5931, Page(s) 626

    MeSH term(s) Amitriptyline/adverse effects ; Apnea/chemically induced ; Cholinesterases/blood ; Electroconvulsive Therapy/mortality ; Humans ; Succinylcholine/adverse effects
    Chemical Substances Amitriptyline (1806D8D52K) ; Cholinesterases (EC 3.1.1.8) ; Succinylcholine (J2R869A8YF)
    Language English
    Publishing date 1974-09-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 80088-0
    ISSN 0007-1447 ; 0267-0623 ; 0959-8138 ; 0959-8146
    ISSN 0007-1447 ; 0267-0623 ; 0959-8138 ; 0959-8146
    DOI 10.1136/bmj.3.5931.626-c
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Flow requirements and rebreathing during mechanically controlled ventilation in a T-piece (Mapleson E)

    Morgan-Hughes, J O

    British journal of anaesthesia

    1988  Volume 60, Issue 7, Page(s) 867

    MeSH term(s) Carbon Dioxide/physiology ; Child ; Humans ; Oxygen/administration & dosage ; Respiration, Artificial/instrumentation
    Chemical Substances Carbon Dioxide (142M471B3J) ; Oxygen (S88TT14065)
    Language English
    Publishing date 1988-06
    Publishing country England
    Document type Letter
    ZDB-ID 80074-0
    ISSN 1471-6771 ; 0007-0912
    ISSN (online) 1471-6771
    ISSN 0007-0912
    DOI 10.1093/bja/60.7.867
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Book ; Online: Confronting Emergent Nuclear-Armed Regional Adversaries

    Morgan, Forrest E / Orletsky, David T / Henry, Ryan / Molander, Roger C / Ratner, Ely

    Prospects for Neutralization, Strategies for Escalation Management

    2015  

    Keywords Nuclear weapons ; Air forces & warfare ; Arms negotiation & control ; History ; Political Science
    Language English
    Size 1 Online-Ressource
    Publisher RAND Corporation
    Document type Book ; Online
    Note English
    HBZ-ID HT030611200
    ISBN 9780833089090 ; 0833089099
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  7. Article: Trichlorethylene (T.C.E.) in obstetrics.

    MORGAN, H S / COLE, F

    Obstetrics and gynecology

    1955  Volume 6, Issue 4, Page(s) 416–419

    MeSH term(s) Analgesia ; Anesthesia ; Anesthesia and Analgesia ; Female ; Humans ; Labor, Obstetric ; Obstetrics ; Pain Management ; Pregnancy ; Trichloroethylene
    Chemical Substances Trichloroethylene (290YE8AR51)
    Language English
    Publishing date 1955-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 207330-4
    ISSN 1873-233X ; 0029-7844
    ISSN (online) 1873-233X
    ISSN 0029-7844
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  8. Article: Computationally Modelling Cholesterol Metabolism and Atherosclerosis.

    Davies, Callum / Morgan, Amy E / Mc Auley, Mark T

    Biology

    2023  Volume 12, Issue 8

    Abstract: Cardiovascular disease (CVD) is the leading cause of death globally. The underlying pathological driver of CVD is atherosclerosis. The primary risk factor for atherosclerosis is elevated low-density lipoprotein cholesterol (LDL-C). Dysregulation of ... ...

    Abstract Cardiovascular disease (CVD) is the leading cause of death globally. The underlying pathological driver of CVD is atherosclerosis. The primary risk factor for atherosclerosis is elevated low-density lipoprotein cholesterol (LDL-C). Dysregulation of cholesterol metabolism is synonymous with a rise in LDL-C. Due to the complexity of cholesterol metabolism and atherosclerosis mathematical models are routinely used to explore their non-trivial dynamics. Mathematical modelling has generated a wealth of useful biological insights, which have deepened our understanding of these processes. To date however, no model has been developed which fully captures how whole-body cholesterol metabolism intersects with atherosclerosis. The main reason for this is one of scale. Whole body cholesterol metabolism is defined by macroscale physiological processes, while atherosclerosis operates mainly at a microscale. This work describes how a model of cholesterol metabolism was combined with a model of atherosclerotic plaque formation. This new model is capable of reproducing the output from its parent models. Using the new model, we demonstrate how this system can be utilized to identify interventions that lower LDL-C and abrogate plaque formation.
    Language English
    Publishing date 2023-08-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2661517-4
    ISSN 2079-7737
    ISSN 2079-7737
    DOI 10.3390/biology12081133
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Why did peri-pandemic suicide death rates decrease among non-Hispanic white people while increasing among most people of color?

    Robison, Morgan / Robertson, Lee / Joiner, T E

    Suicide & life-threatening behavior

    2024  

    Abstract: ... in the early pandemic phases.: Results: We propose both distal (i.e., tele-mental health usage, internet and ...

    Abstract Introduction: While suicides in the United States decreased during the COVID-19 pandemic, statistically significant decreases have been limited to White people throughout a large portion of 2020.
    Methods: This paper outlines possible explanations for racial/ethnic differences in suicidality in the early pandemic phases.
    Results: We propose both distal (i.e., tele-mental health usage, internet and technology access, employment protections, and economic security) and proximal (cultural beliefs, coping strategies, clustering, pulling together, and embracing life) factors that may have helped build and foster community and mental wellness. However, this paper argues these factors did not extend, or did not extend as much, to many communities of color.
    Conclusions: We argue that these disparities are due to the myriad effects of discrimination and systemic racism, encapsulated broadly by the minority stress theory, and provide suggestions for relief and research.
    Language English
    Publishing date 2024-04-27
    Publishing country England
    Document type Journal Article
    ZDB-ID 750058-0
    ISSN 1943-278X ; 0047-4592 ; 0363-0234
    ISSN (online) 1943-278X
    ISSN 0047-4592 ; 0363-0234
    DOI 10.1111/sltb.13088
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Tranexamic Acid in Tumescence for Cervicofacial Rhytidectomies.

    Trimas, Gracen E / Frost, Morgan D T / Trimas, Scott J

    Plastic and reconstructive surgery. Global open

    2024  Volume 12, Issue 1, Page(s) e5540

    Abstract: Background: Cervicofacial rhytidectomies are one of the most common procedures in the United States. There are many different methods and techniques involved, but all aim to minimize blood loss and procedure time. In our study, we investigated the ... ...

    Abstract Background: Cervicofacial rhytidectomies are one of the most common procedures in the United States. There are many different methods and techniques involved, but all aim to minimize blood loss and procedure time. In our study, we investigated the addition of tranexamic acid (TXA) to tumescent anesthesia during rhytidectomy procedures. Our objective was to analyze the difference in mean procedure time and estimated blood loss in patients undergoing both general and other anesthesia types, with and without the addition of TXA, while maintaining patient safety.
    Methods: Seventy-four patients underwent a standard superficial musculoaponeurotic system plication technique rhytidectomy, with 60 patients undergoing general anesthesia and the remaining 14 undergoing other anesthesia types. Forty patients were treated without TXA, whereas the remaining 34 were treated with TXA.
    Results: Although the difference was not statistically significant, the addition of TXA resulted in a lower procedure time and estimated blood loss. Within anesthesia type, there was also a slight difference that TXA decreased blood loss and procedure time. We did find that general anesthesia type does significantly impact procedure time and estimated blood loss, when compared with other anesthesia types, independent of TXA use.
    Conclusion: The use of tumescent TXA may allow for a faster procedure with less blood loss, although further studies with a larger sample size are needed.
    Language English
    Publishing date 2024-01-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2851682-5
    ISSN 2169-7574 ; 2169-7574
    ISSN (online) 2169-7574
    ISSN 2169-7574
    DOI 10.1097/GOX.0000000000005540
    Database MEDical Literature Analysis and Retrieval System OnLINE

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