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  1. Article ; Online: Prevalenza dei dolcificanti artificiali negli integratori multivitaminici registrati in Italia.

    Antonelli, Michele / Donelli, Davide

    Recenti progressi in medicina

    2024  Volume 115, Issue 2, Page(s) 82–84

    Abstract: This study aims to evaluate the prevalence of artificial sweeteners in multivitamin supplements registered in Italy. The National Registry of Dietary Supplements was examined in December 2023 to extract data relating to supplements identified as " ... ...

    Title translation Prevalence of artificial sweeteners in multivitamin supplements registered in Italy.
    Abstract This study aims to evaluate the prevalence of artificial sweeteners in multivitamin supplements registered in Italy. The National Registry of Dietary Supplements was examined in December 2023 to extract data relating to supplements identified as "multivitamins". Then, for each supplement the specific composition was searched online. 179 multivitamin products were identified, and for 96 of them it was possible to access the complete list of their ingredients online. Among these, 47 supplements (49%) do not contain added sugars, while the remaining 49 (51%) have one or more sweeteners in their composition (29 of which have at least two among the ingredients). Among the 49 supplements in the second group, the greatest prevalence of artificial sweeteners is found in effervescent tablets (100%), soluble powders (100%) and gummies or chewing tablets (63%), while the lowest prevalence was detected in capsules/tablets to be swallowed (19%). In relative terms, aspartame and sucralose are mostly found in effervescent tablets and diluted powders, but other formulations are not always free of these substances. In conclusion, the significant presence of artificial sweeteners in multivitamin supplements requires attention, especially considering the long-term health impact. Consumer awareness and medical evaluation are crucial for an informed choice and the protection of health.
    MeSH term(s) Humans ; Sweetening Agents ; Prevalence ; Dietary Supplements ; Vitamins ; Aspartame
    Chemical Substances Sweetening Agents ; Vitamins ; Aspartame (Z0H242BBR1)
    Language Italian
    Publishing date 2024-01-30
    Publishing country Italy
    Document type English Abstract ; Journal Article
    ZDB-ID 138266-4
    ISSN 2038-1840 ; 0034-1193
    ISSN (online) 2038-1840
    ISSN 0034-1193
    DOI 10.1701/4197.41841
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Silence and its effects on the autonomic nervous system: A systematic review.

    Donelli, Davide / Lazzeroni, Davide / Rizzato, Matteo / Antonelli, Michele

    Progress in brain research

    2023  Volume 280, Page(s) 103–144

    Abstract: This systematic review explores the influence of silence on the autonomic nervous system. The Polyvagal Theory has been used as a reference model to describe the autonomic nervous system by explaining its role in emotional regulation, social engagement, ... ...

    Abstract This systematic review explores the influence of silence on the autonomic nervous system. The Polyvagal Theory has been used as a reference model to describe the autonomic nervous system by explaining its role in emotional regulation, social engagement, and adaptive physiological responses. PubMed, Scopus, PsycInfo, EMBASE, and Google Scholar were systematically searched up until July 2023 for relevant studies. The literature search yielded 511 results, and 37 studies were eventually included in this review. Silence affects the autonomic nervous system differently based on whether it is inner or outer silence. Inner silence enhances activity of the ventral vagus, favoring social engagement, and reducing sympathetic nervous system activity and physiological stress. Outer silence, conversely, can induce a heightened state of alertness, potentially triggering vagal brake removal and sympathetic nervous system activation, though with training, it can foster inner silence, preventing such activation. The autonomic nervous system response to silence can also be influenced by other factors such as context, familiarity with silence, presence and quality of outer noise, and empathy.
    MeSH term(s) Humans ; Autonomic Nervous System ; Vagus Nerve ; Emotional Regulation ; Empathy ; Recognition, Psychology
    Language English
    Publishing date 2023-09-01
    Publishing country Netherlands
    Document type Systematic Review ; Journal Article
    ISSN 1875-7855 ; 0079-6123
    ISSN (online) 1875-7855
    ISSN 0079-6123
    DOI 10.1016/bs.pbr.2023.08.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Olfactory training with essential oils for patients with post-COVID-19 smell dysfunction: A case series.

    Donelli, Davide / Antonelli, Michele / Valussi, Marco

    European journal of integrative medicine

    2023  Volume 60, Page(s) 102253

    Abstract: Introduction: It is estimated that up to one third of COVID-19 patients can develop long-lasting smell dysfunction. Viral infections, especially COVID-19, can cause anosmia through different pathomechanisms, and different strategies have been proposed ... ...

    Abstract Introduction: It is estimated that up to one third of COVID-19 patients can develop long-lasting smell dysfunction. Viral infections, especially COVID-19, can cause anosmia through different pathomechanisms, and different strategies have been proposed for effectively managing post-COVID-19 olfactory dysfunction in clinical practice, with olfactory training being recommended as a first-line treatment option.
    Methods: This report describes a non-consecutive series of clinical cases. After COVID-19, eight cases (5 females, 3 males) of adult patients with long-lasting (3+ months) post-viral smell dysfunction followed a 30-day olfactory training protocol with a set of plant-derived essential oils. At baseline and at the end of the treatment, the patients were administered the Assessment of Self-reported Olfactory Functioning (ASOF) questionnaire, an inventory used to measure olfactory dysfunction and health-related quality of life.
    Results: For any of the outcomes assessed with the ASOF scale, a significant improvement from baseline was reported, even though mean value ameliorations were more pronounced for olfactory function per se (Subjective Olfactory Capability: from 3.6 to 5.6 out of 10; Self-Reported capability of Perceiving specific odors: from 1.8 to 3.0 out of 5), rather than for health-related quality of life (Olfactory-Related Quality of life: from 2.9 to 3.9 out of 6).
    Conclusions: It was observed that patients with long-lasting COVID-19-related smell dysfunction improved after a 30-day olfactory training protocol. Further controlled clinical studies would be useful to better investigate the role of olfactory training in patients with postviral smell dysfunction.
    Language English
    Publishing date 2023-04-14
    Publishing country Netherlands
    Document type Case Reports
    ZDB-ID 2467260-9
    ISSN 1876-3839 ; 1876-3820
    ISSN (online) 1876-3839
    ISSN 1876-3820
    DOI 10.1016/j.eujim.2023.102253
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Reading and understanding scientific articles.

    Antonelli, Michele / Donelli, Davide

    The clinical teacher

    2020  Volume 17, Issue 6, Page(s) 612–616

    MeSH term(s) Humans ; Reading
    Language English
    Publishing date 2020-04-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 2151518-9
    ISSN 1743-498X ; 1743-4971
    ISSN (online) 1743-498X
    ISSN 1743-4971
    DOI 10.1111/tct.13159
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Effects of Static Meditation Practice on Blood Lipid Levels: A Systematic Review and Meta-Analysis.

    Antonelli, Michele / Donelli, Davide / Gurgoglione, Filippo Luca / Lazzeroni, Davide / Halasz, Geza / Niccoli, Giampaolo

    Healthcare (Basel, Switzerland)

    2024  Volume 12, Issue 6

    Abstract: This review aims to delineate the potential impact of static meditation practice on cholesterol and triglyceride levels. PubMed, EMBASE, Web of Science, Cochrane Library, and Google Scholar were systematically screened up until December 2023 to identify ... ...

    Abstract This review aims to delineate the potential impact of static meditation practice on cholesterol and triglyceride levels. PubMed, EMBASE, Web of Science, Cochrane Library, and Google Scholar were systematically screened up until December 2023 to identify pertinent studies. After searching the scientific literature, 16 clinical studies (11 trials and 5 observational experiments) met the criteria for inclusion, involving a total of 1147 participants. In general, Ayurvedic-based meditation techniques were predominantly associated with lower total cholesterol levels, mindfulness-based techniques demonstrated benefits in both total cholesterol and triglyceride levels, and Eastern meditation techniques with spiritual origins were primarily linked to improved serum concentrations of HDL cholesterol. Study participants mostly engaged in meditation on a daily basis, often practicing it once or even twice a day, spanning a duration ranging from a few weeks to several months. The meta-analysis shows an association between meditation practice in healthy or sub-healthy adults and reduced cholesterol levels, with an average decrease of approximately -14 mg/dL (MD = -13.91 [-23.35; -4.47] mg/dL;
    Language English
    Publishing date 2024-03-14
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2721009-1
    ISSN 2227-9032
    ISSN 2227-9032
    DOI 10.3390/healthcare12060655
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Efficacy, Safety and Tolerability of Aroma Massage with Lavender Essential Oil: an Overview.

    Antonelli, Michele / Donelli, Davide

    International journal of therapeutic massage & bodywork

    2020  Volume 13, Issue 1, Page(s) 32–36

    Language English
    Publishing date 2020-02-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2452024-X
    ISSN 1916-257X
    ISSN 1916-257X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Treatment of Achilles tendon partial injuries with injection of peripheral blood mononuclear cells (PB-MNCs): a case series.

    Caravaggio, Francesco / Depalmi, Fabio / Antonelli, Michele

    European journal of translational myology

    2022  

    Abstract: Three patients with Achilles tendon partial injury were treated with local injection of peripheral blood mononuclear cells (PB-MNCs). All subjects were evaluated both clinically (American Orthopedic Foot and Ankle Society - AOFAS scale) and ... ...

    Abstract Three patients with Achilles tendon partial injury were treated with local injection of peripheral blood mononuclear cells (PB-MNCs). All subjects were evaluated both clinically (American Orthopedic Foot and Ankle Society - AOFAS scale) and radiologically (MRI examination) at 2 months, and a clinical reassessment with the AOFAS scale was performed at 6 months. Functional and radiological signs of tendon healing processes were detected as early as 2 months after the procedure and the AOFAS scale rose from an initial average value of 37.0 to 82.7. Even though this study only involved a limited number of participants, our preliminary results indicate that regenerative therapies with PB-MNCs may be a valid alternative to surgical options for Achilles tendon partial injuries, especially in patients with contraindications to surgery, when other conservative approaches (exercises, physical therapies, sclerosing treatment) have failed. Further investigations on the subject seem rationally supported and advisable.
    Language English
    Publishing date 2022-11-02
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2545577-1
    ISSN 2037-7460 ; 2037-7452
    ISSN (online) 2037-7460
    ISSN 2037-7452
    DOI 10.4081/ejtm.2022.10768
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Defining a new perspective in Environmental Health: the healing environment.

    Antonelli, Michele / Barbieri, Grazia / Donelli, Davide

    International journal of biometeorology

    2022  Volume 66, Issue 5, Page(s) 1039–1044

    Abstract: With pollution-related health problems on the rise, the focus of modern Environmental Health (EH) has mostly been placed on toxicology and exposure science. Despite the importance of toxicological aspects, the environment should be studied not only to ... ...

    Abstract With pollution-related health problems on the rise, the focus of modern Environmental Health (EH) has mostly been placed on toxicology and exposure science. Despite the importance of toxicological aspects, the environment should be studied not only to identify pollution-related hazards, but also to investigate potentially therapeutic and health-enhancing effects of its elements. Generally speaking, it is possible to benefit from a natural environment with a full-immersion experience or with a single-element interaction. Recently, scientific evidence is accumulating on the beneficial effects of natural settings for well-being promotion and psycho-physical health, especially for stress reduction and prevention of stress-related conditions. In light of these considerations, the paradigm of EH can change: the environment we live in should be considered not only as a precious resource to be protected against pollution (thus preventing the consequent health hazards), but, in a proactive vision, also as a potential source of elements capable of actively maintaining and promoting health and well-being.
    MeSH term(s) Environment ; Environmental Health
    Language English
    Publishing date 2022-02-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 280324-0
    ISSN 1432-1254 ; 0020-7128
    ISSN (online) 1432-1254
    ISSN 0020-7128
    DOI 10.1007/s00484-022-02251-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Defining a new perspective in Environmental Health: the healing environment

    Antonelli, Michele / Barbieri, Grazia / Donelli, Davide

    International journal of biometeorology. 2022 May, v. 66, no. 5

    2022  

    Abstract: With pollution-related health problems on the rise, the focus of modern Environmental Health (EH) has mostly been placed on toxicology and exposure science. Despite the importance of toxicological aspects, the environment should be studied not only to ... ...

    Abstract With pollution-related health problems on the rise, the focus of modern Environmental Health (EH) has mostly been placed on toxicology and exposure science. Despite the importance of toxicological aspects, the environment should be studied not only to identify pollution-related hazards, but also to investigate potentially therapeutic and health-enhancing effects of its elements. Generally speaking, it is possible to benefit from a natural environment with a full-immersion experience or with a single-element interaction. Recently, scientific evidence is accumulating on the beneficial effects of natural settings for well-being promotion and psycho-physical health, especially for stress reduction and prevention of stress-related conditions. In light of these considerations, the paradigm of EH can change: the environment we live in should be considered not only as a precious resource to be protected against pollution (thus preventing the consequent health hazards), but, in a proactive vision, also as a potential source of elements capable of actively maintaining and promoting health and well-being.
    Keywords bioclimatology ; environmental health ; pollution ; therapeutics ; toxicology ; vision
    Language English
    Dates of publication 2022-05
    Size p. 1039-1044.
    Publishing place Springer Berlin Heidelberg
    Document type Article
    ZDB-ID 127361-9
    ISSN 0067-8902 ; 0020-7128
    ISSN 0067-8902 ; 0020-7128
    DOI 10.1007/s00484-022-02251-z
    Database NAL-Catalogue (AGRICOLA)

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  10. Article ; Online: Respiratory rehabilitation for post-COVID19 patients in spa centers: first steps from theory to practice.

    Antonelli, Michele / Donelli, Davide

    International journal of biometeorology

    2020  Volume 64, Issue 10, Page(s) 1811–1813

    Abstract: With this correspondence, we would like to briefly outline a practical perspective about a possible integrative and effective management in spa settings of COVID-19 long-term sequelae, with a keen focus on post-infective lung damage and fibrosis, which ... ...

    Abstract With this correspondence, we would like to briefly outline a practical perspective about a possible integrative and effective management in spa settings of COVID-19 long-term sequelae, with a keen focus on post-infective lung damage and fibrosis, which is expected to become epidemiologically relevant in the general population. In order to outline a standard/baseline model of care, we think that it can be useful to refer to already existing rehabilitative plans with a long-standing tradition in Italy, such as those ones prescribed for work-related respiratory diseases like pneumoconiosis, in which long-term outcomes share some clinical characteristics with post-infective lung fibrosis. Such programs include diagnostic procedures (spirometry, ECG, blood tests) and treatments like respiratory physio-kinesiotherapy and postural drainage of the lungs; mechanical pulmonary ventilation for rehabilitative purposes, with or without drugs, along with standard medical and, when required, oxygen therapy; inhalation therapies with mineral waters; physical activity and psychological support. In conclusion, we believe that spa facilities can be a proper setting for respiratory rehabilitation and that already existing programs employed in occupational medicine can be a good starting point to plan rehabilitative strategies for post-COVID-19 patients. In particular, health spa centers can be useful not only to offer tailored programs of physical rehabilitation but also to provide patients with a psychologically supportive and health-promoting environment. Further studies on the topic are advised to properly assess and quantify with adequate outcome measurements the beneficial effect of a spa-based rehabilitative program in post-COVID-19 patients.
    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections ; Humans ; Italy ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-07-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 280324-0
    ISSN 1432-1254 ; 0020-7128
    ISSN (online) 1432-1254
    ISSN 0020-7128
    DOI 10.1007/s00484-020-01962-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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