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  1. Book ; Conference proceedings: The role of plant pathology in food safety and food security

    Strange, Richard N.

    [this collection of papers represents some of those given at the International Congress for Plant Pathology held in Turin in 2008 in the Session with the Title "The Role of Plant Pathology in Food Safety and Food Security"]

    (Plant Pathology in the 21st Century ; 3)

    2010  

    Institution Società Italiana di Patologia Vegetale
    Event/congress Session with the Title the Role of Plant Pathology in Food Safety and Food Security (2008, Turin) ; International Congress of Plant Pathology (9, 2008, Turin)
    Author's details [Società Italiana di Patologia Vegetale]. R. N. Strange ... ed
    Series title Plant Pathology in the 21st Century ; 3
    Plant pathology in the 21st century
    Plant Pathology in the 21st Century
    Collection Plant pathology in the 21st century
    Plant Pathology in the 21st Century
    Language English
    Size VIII, 155 S. : Ill., graph. Darst.
    Publisher Springer
    Publishing place Dordrecht u.a.
    Publishing country Netherlands
    Document type Book ; Conference proceedings
    HBZ-ID HT015921895
    ISBN 978-1-4020-8931-2 ; 9781402089329 ; 1-4020-8931-7 ; 1402089325
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

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  2. Book: Plant disease control

    Strange, Richard N.

    towards environmentally acceptable methods

    1993  

    Author's details Richard N. Strange
    Keywords Pflanzenschutz ; Umweltverträglichkeit
    Subject Umweltfreundlich ; Umweltschonend
    Size XII, 354 S. : Ill., graph. Darst., Kt.
    Edition 1. ed.
    Publisher Chapman & Hall
    Publishing place London u.a.
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT004945389
    ISBN 0-412-33610-3 ; 978-0-412-33610-2
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

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  3. Article: Phytotoxins produced by microbial plant pathogens.

    Strange, Richard N

    Natural product reports

    2007  Volume 24, Issue 1, Page(s) 127–144

    Abstract: Phytotoxic compounds produced by plant pathogens are often crucial determinants of plant disease. Knowledge of them provides insights into disease syndromes and may be exploited by conventional breeding and biotechnology to obtain resistant crops. ...

    Abstract Phytotoxic compounds produced by plant pathogens are often crucial determinants of plant disease. Knowledge of them provides insights into disease syndromes and may be exploited by conventional breeding and biotechnology to obtain resistant crops.
    MeSH term(s) Bacterial Toxins ; Plant Diseases/etiology ; Plant Diseases/microbiology ; Plants, Genetically Modified/microbiology ; Structure-Activity Relationship
    Chemical Substances Bacterial Toxins
    Language English
    Publishing date 2007-02
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2002546-4
    ISSN 1460-4752 ; 0265-0568
    ISSN (online) 1460-4752
    ISSN 0265-0568
    DOI 10.1039/b513232k
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Immunoprofiles of human Sertoli cells infected with Zika virus reveals unique insights into host-pathogen crosstalk.

    Strange, Daniel P / Green, Richard / Siemann, David N / Gale, Michael / Verma, Saguna

    Scientific reports

    2018  Volume 8, Issue 1, Page(s) 8702

    Abstract: Confirmed reports of Zika virus (ZIKV) in seminal fluid months after clearance of viremia suggests that ZIKV can establish persistent infection in the seminiferous tubules, an immune privileged site of the testis. The seminiferous tubule epithelium is ... ...

    Abstract Confirmed reports of Zika virus (ZIKV) in seminal fluid months after clearance of viremia suggests that ZIKV can establish persistent infection in the seminiferous tubules, an immune privileged site of the testis. The seminiferous tubule epithelium is mainly composed of Sertoli cells that function to nourish and protect developing germ cells. We recently demonstrated that primary human Sertoli cells (hSeC) were highly susceptible to ZIKV as compared to dengue virus without causing cell death and thus may act as a reservoir for ZIKV in the testes. However, the cellular and immune responses of hSeC to infection with ZIKV or any other virus are not yet characterized. Using genome-wide RNA-seq to compare immunoprofiles of hSeC, we show that the most prominent response to ZIKV at early stage of infection was suppression of cell growth and proliferation functional pathways. Peak virus replication was associated with induction of multiple antiviral defense pathways. Unique ZIKV-associated signatures included dysregulation of germ cell-Sertoli cell junction signaling. This study demonstrates that hSeC are capable of signaling through canonical pro-inflammatory pathways and provides insights into unique cell-type-specific response induced by ZIKV in association with viral persistence in the testes.
    MeSH term(s) Cell Line ; Host-Pathogen Interactions/immunology ; Humans ; Male ; Sertoli Cells/immunology ; Sertoli Cells/pathology ; Sertoli Cells/virology ; Zika Virus/physiology ; Zika Virus Infection/immunology ; Zika Virus Infection/pathology
    Language English
    Publishing date 2018-06-07
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-018-27027-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Phytotoxins produced by microbial plant pathogens

    Strange, Richard N.

    Natural product reports. 2007 Jan. 31, v. 24, no. 1

    2007  

    Abstract: Phytotoxic compounds produced by plant pathogens are often crucial determinants of plant disease. Knowledge of them provides insights into disease syndromes and may be exploited by conventional breeding and biotechnology to obtain resistant crops. ...

    Abstract Phytotoxic compounds produced by plant pathogens are often crucial determinants of plant disease. Knowledge of them provides insights into disease syndromes and may be exploited by conventional breeding and biotechnology to obtain resistant crops.
    Keywords biotechnology ; phytotoxicity ; phytotoxins
    Language English
    Dates of publication 2007-0131
    Size p. 127-144.
    Publishing place The Royal Society of Chemistry
    Document type Article
    ZDB-ID 2002546-4
    ISSN 1460-4752 ; 0265-0568
    ISSN (online) 1460-4752
    ISSN 0265-0568
    DOI 10.1039/b513232k
    Database NAL-Catalogue (AGRICOLA)

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  6. Article ; Online: Immunoprofiles of human Sertoli cells infected with Zika virus reveals unique insights into host-pathogen crosstalk

    Daniel P. Strange / Richard Green / David N. Siemann / Michael Gale / Saguna Verma

    Scientific Reports, Vol 8, Iss 1, Pp 1-

    2018  Volume 15

    Abstract: Abstract Confirmed reports of Zika virus (ZIKV) in seminal fluid months after clearance of viremia suggests that ZIKV can establish persistent infection in the seminiferous tubules, an immune privileged site of the testis. The seminiferous tubule ... ...

    Abstract Abstract Confirmed reports of Zika virus (ZIKV) in seminal fluid months after clearance of viremia suggests that ZIKV can establish persistent infection in the seminiferous tubules, an immune privileged site of the testis. The seminiferous tubule epithelium is mainly composed of Sertoli cells that function to nourish and protect developing germ cells. We recently demonstrated that primary human Sertoli cells (hSeC) were highly susceptible to ZIKV as compared to dengue virus without causing cell death and thus may act as a reservoir for ZIKV in the testes. However, the cellular and immune responses of hSeC to infection with ZIKV or any other virus are not yet characterized. Using genome-wide RNA-seq to compare immunoprofiles of hSeC, we show that the most prominent response to ZIKV at early stage of infection was suppression of cell growth and proliferation functional pathways. Peak virus replication was associated with induction of multiple antiviral defense pathways. Unique ZIKV-associated signatures included dysregulation of germ cell-Sertoli cell junction signaling. This study demonstrates that hSeC are capable of signaling through canonical pro-inflammatory pathways and provides insights into unique cell-type-specific response induced by ZIKV in association with viral persistence in the testes.
    Keywords Medicine ; R ; Science ; Q
    Subject code 570
    Language English
    Publishing date 2018-06-01T00:00:00Z
    Publisher Nature Publishing Group
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Percutaneous Left Ventricular Unloading During High-Risk Coronary Intervention: Rationale and Design of the CHIP-BCIS3 Randomized Controlled Trial.

    Ryan, Matthew / Ezad, Saad M / Webb, Ian / O'Kane, Peter D / Dodd, Matthew / Evans, Richard / Laidlaw, Lynn / Khan, Sohail Q / Weerackody, Roshan / Bagnall, Alan / Panoulas, Vasileios F / Rahman, Haseeb / Strange, Julian W / Fath-Ordoubadi, Farzin / Hoole, Stephen P / Stables, Rod H / Curzen, Nick / Clayton, Tim / Perera, Divaka

    Circulation. Cardiovascular interventions

    2024  Volume 17, Issue 3, Page(s) e013367

    Abstract: Introduction: Percutaneous coronary intervention for complex coronary disease is associated with a high risk of cardiogenic shock. This can cause harm and limit the quality of revascularization achieved, especially when left ventricular function is ... ...

    Abstract Introduction: Percutaneous coronary intervention for complex coronary disease is associated with a high risk of cardiogenic shock. This can cause harm and limit the quality of revascularization achieved, especially when left ventricular function is impaired at the outset. Elective percutaneous left ventricular unloading is increasingly used to mitigate adverse events in patients undergoing high-risk percutaneous coronary intervention, but this strategy has fiscal and clinical costs and is not supported by robust evidence.
    Methods: CHIP-BCIS3 (Controlled Trial of High-Risk Coronary Intervention With Percutaneous Left Ventricular Unloading) is a prospective, multicenter, open-label randomized controlled trial that aims to determine whether a strategy of elective percutaneous left ventricular unloading is superior to standard care (no planned mechanical circulatory support) in patients undergoing nonemergent high-risk percutaneous coronary intervention. Patients are eligible for recruitment if they have severe left ventricular systolic dysfunction, extensive coronary artery disease, and are due to undergo complex percutaneous coronary intervention (to the left main stem with calcium modification or to a chronic total occlusion with a retrograde approach). Cardiogenic shock and acute ST-segment-elevation myocardial infarction are exclusions. The primary outcome is a hierarchical composite of all-cause death, stroke, spontaneous myocardial infarction, cardiovascular hospitalization, and periprocedural myocardial infarction, analyzed using the win ratio. Secondary outcomes include completeness of revascularization, major bleeding, vascular complications, health economic analyses, and health-related quality of life. A sample size of 250 patients will have in excess of 80% power to detect a hazard ratio of 0.62 at a minimum of 12 months, assuming 150 patients experience an event across all follow-up.
    Conclusions: To date, 169 patients have been recruited from 21 National Health Service hospitals in the United Kingdom, with recruitment expected to complete in 2024.
    Registration: URL: https://www.clinicaltrials.gov; Unique identifier: NCT05003817.
    MeSH term(s) Humans ; Coronary Artery Disease/diagnostic imaging ; Coronary Artery Disease/therapy ; Myocardial Infarction/etiology ; Percutaneous Coronary Intervention/adverse effects ; Prospective Studies ; Quality of Life ; Shock, Cardiogenic/diagnosis ; Shock, Cardiogenic/therapy ; Shock, Cardiogenic/etiology ; State Medicine ; Treatment Outcome ; Randomized Controlled Trials as Topic ; Multicenter Studies as Topic
    Language English
    Publishing date 2024-02-27
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2450797-0
    ISSN 1941-7632 ; 1941-7640
    ISSN (online) 1941-7632
    ISSN 1941-7640
    DOI 10.1161/CIRCINTERVENTIONS.123.013367
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Book: Introduction to plant pathology

    Strange, Richard N

    2003  

    Author's details Richard N. Strange
    Keywords Plant diseases.
    Language English
    Size xvi, 464 p. :, ill. (some col.) ;, 25 cm.
    Publisher Wiley
    Publishing place New York, NY, USA
    Document type Book
    ISBN 047084972X ; 0470849738 ; 9780470849729 ; 9780470849736
    Database NAL-Catalogue (AGRICOLA)

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  9. Book: Introduction to plant pathology

    Strange, Richard N

    2003  

    Author's details Richard N. Strange
    Keywords Phytopathologie
    Language English
    Size XVI, 464 S, Ill., graph. Darst, 24 cm
    Publisher Wiley
    Publishing place Chichester
    Document type Book
    ISBN 047084972X ; 0470849738 ; 9780470849729 ; 9780470849736
    Database Julius Kühn-Institute

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  10. Book: Introduction to plant pathology

    Strange, Richard N

    2003  

    Author's details Richard N. Strange
    Keywords Phytopathologie
    Language English
    Size XVI, 464 S, Ill., graph. Darst, 24 cm
    Publisher Wiley
    Publishing place Chichester
    Document type Book
    ISBN 047084972X ; 0470849738 ; 9780470849729 ; 9780470849736
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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