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Book ; Online: Optimization-based modelling and game-theoretic framework for techno-economic analysis of demand-side flexibility

Sayfutdinov, Timur / Patsios, Charalampos / Greenwood, David / Peker, Meltem / Sarantakos, Ilias

a real case study

2021

Abstract: This paper proposes a two-step framework for techno-economic analysis of a demand-side flexibility service in distribution networks. Step one applies optimization-based modelling to propose a generic problem formulation which determines the offer curve, ... ...

Abstract	This paper proposes a two-step framework for techno-economic analysis of a demand-side flexibility service in distribution networks. Step one applies optimization-based modelling to propose a generic problem formulation which determines the offer curve, in terms of available flexible capacity and its marginal cost, for flexible distribution-connected assets. These offer curves form an input to the second step, which uses a multi-agent iterative game framework to determine the benefits of demand-side flexibility for the Distribution System Operator (DSO) and the service providers. The combined two-step framework simultaneously accounts for the objectives of each flexibility provider, technical constraints of flexible assets, customer preferences, market clearing mechanisms, and strategic bidding by service providers, omission of any of which can lead to erroneous results. The proposed two-step framework has been applied to a real case study in the North East of England to examine four market mechanisms and three bidding strategies. The results showed that among all considered market mechanisms, flexibility markets that operate under discriminatory pricing, such as pay-as-bid and Dutch reverse auctions, are prone to manipulations, especially in the lack of competition. In contrast, uniform pricing pay-as-cleared auction provides limited opportunities for manipulation even when competition is low. Comment: 33 pages, 5 figures, submitted to Applied Energy
Keywords	Electrical Engineering and Systems Science - Systems and Control
Subject code	330
Publishing date	2021-10-14
Publishing country	us
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: An unusual case of intercostal muscle flap ossification mimicking an intrathoracic rib.

Abdullah, Sharif / Guo, Ming Hao / Darling, Gail / Patsios, Demetris

BJR case reports

2016 Volume 2, Issue 4, Page(s) 20150469

Abstract: We present a unique case of intercostal muscle flap (ICMF) ossification mimicking an intrathoracic rib diagnosed 3 years after oesophageal perforation repair. A 58-year-old male presented with complaints of mild chest discomfort. Three years ago he had ... ...

Abstract	We present a unique case of intercostal muscle flap (ICMF) ossification mimicking an intrathoracic rib diagnosed 3 years after oesophageal perforation repair. A 58-year-old male presented with complaints of mild chest discomfort. Three years ago he had undergone left thoracotomy and primary repair of post-emetic oesophageal perforation. An ICMF had been used to strengthen the repair. Chest X-ray identified a linear calcific density within the left hemithorax. Subsequent thoracic CT characterized the anomaly as ossification of the ICMF. The lesion had the appearance of a well-differentiated intrathoracic rib coursing through the left lower lobe. We discuss the typical appearances of ossified ICMFs and the potential complications resulting from this ossification.
Language	English
Publishing date	2016-11-02
Publishing country	England
Document type	Case Reports
ISSN	2055-7159
ISSN (online)	2055-7159
DOI	10.1259/bjrcr.20150469
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Article ; Online: Qualitative assessment of pain management in patients undergoing computed tomography-guided transthoracic lung biopsy.

Wong, Erin Thomas / Dunham, Carol / Patsios, Demetris

Pain research & management

2014 Volume 19, Issue 3, Page(s) 149–152

Abstract: Background: Unpublished questionnaire data collected by the authors' institution (Toronto General Hospital, Toronto, Ontario) indicates that patients often experience significant pain while undergoing lung biopsy, yet receive only a fraction of the ... ...

Abstract	Background: Unpublished questionnaire data collected by the authors' institution (Toronto General Hospital, Toronto, Ontario) indicates that patients often experience significant pain while undergoing lung biopsy, yet receive only a fraction of the maximum allowable dosage of analgesic. Objectives: To qualitatively assess current pain management practices from the patient perspective. Patient education and patient satisfaction were also evaluated. Methods: From March through June 2012, participants were contacted via telephone within one week of their procedure until data saturation was reached. The semistructured interviews were based on a study-specific interview template. Thematic analysis of qualitative study data was used to identify recurring interview topics. Results: A consecutive sample of 16 outpatients who had undergone image-guided transthoracic lung biopsy at the authors' institution were interviewed. None of the study participants reported noteworthy pain associated with the insertion of lung biopsy needles. The most significant pain was caused by positioning within the computed tomography scanner, particularly among participants who were in the prone position. All participants reported high satisfaction with the amount of analgesic received. Potential complications and recovery period details were identified as areas for improved patient education. Conclusions: At the authors' institution, pain associated with lung biopsy needle insertion was well controlled. Positional pain is common for patients required to be in the prone position. Potential solutions include increasing awareness of positional pain and instituting additional supportive equipment.
MeSH term(s)	Aged ; Aged, 80 and over ; Biopsy/adverse effects ; Humans ; Lung Diseases/pathology ; Middle Aged ; Pain/diagnosis ; Pain/etiology ; Pain Management ; Patient Satisfaction/statistics & numerical data ; Surveys and Questionnaires ; Tomography, X-Ray Computed/adverse effects
Language	English
Publishing date	2014-04-22
Publishing country	United States
Document type	Journal Article
ZDB-ID	2041085-2
ISSN	1918-1523 ; 1203-6765
ISSN (online)	1918-1523
ISSN	1203-6765
DOI	10.1155/2014/194519
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Article ; Online: The organisation of interagency training to safeguard children in England: a case study using realistic evaluation.

Patsios, Demi / Carpenter, John

International journal of integrated care

2010 Volume 10, Page(s) e61

Abstract: Background: Joint training for interagency working is carried out by Local Safeguarding Children Boards in England to promote effective local working to safeguard and promote the welfare of children.: Purpose: This paper reports on the findings of ... ...

Abstract	Background: Joint training for interagency working is carried out by Local Safeguarding Children Boards in England to promote effective local working to safeguard and promote the welfare of children. Purpose: This paper reports on the findings of the outputs and outcomes of interagency training to safeguard children in eight Local Safeguarding Children Boards. Methods: A review of Local Safeguarding Children Board documentation, observations of Local Safeguarding Children Board training sub-group meetings and a series of interviews with training key stakeholders in each Local Safeguarding Children Board were used to assess how partner agencies in the Local Safeguarding Children Boards carried out their statutory responsibilities to organise interagency training. 'Realistic Evaluation' was used to evaluate the mechanisms by which a central government mandate produced particular inter-agency training outputs (number of courses, training days) and joint working outcomes (effective partnerships), within particular Local Safeguarding Children Board contexts. Results: The 'mandated partnership' imposed on Local Safeguarding Children Boards by central government left little choice but for partner agencies to work together to deliver joint training, which in turn affected the dynamics of working partnerships across the various sites. The effectiveness of the training sub group determined the success of the organisation and delivery of training for joint working. Despite having a central mandate, Local Safeguarding Children Boards had heterogeneous funding and training arrangements. These resulted in significant variations in the outputs in terms of the number of courses per 'children in need' in the locality and in the cost per course. Conclusions: Interagency training which takes account of the context of the Local Safeguarding Children Board is more likely to produce better trained staff, effective partnership working, and lead to better integrated safeguarding children services.
Language	English
Publishing date	2010-11-16
Publishing country	England
Document type	Journal Article
ZDB-ID	2119289-3
ISSN	1568-4156 ; 1568-4156
ISSN (online)	1568-4156
ISSN	1568-4156
DOI	10.5334/ijic.548
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Article ; Online: Outcomes of short course interprofessional training in domestic violence and child protection.

Szilassy, Eszter / Carpenter, John / Patsios, Demi / Hackett, Simon

Violence against women

2013 Volume 19, Issue 11, Page(s) 1370–1383

Abstract: The interrelationship between domestic violence and child protection is well established, yet deficiencies in interprofessional collaboration have been reported and training is advocated as a solution. This study evaluates the outcomes of short ... ...

Abstract	The interrelationship between domestic violence and child protection is well established, yet deficiencies in interprofessional collaboration have been reported and training is advocated as a solution. This study evaluates the outcomes of short interagency and interprofessional training in domestic abuse. Participants' attitudes and knowledge were assessed using a self-report scale and compared in a double-baseline time-series design. Participants (N = 177) were recruited from a range of agencies in England. There were consistent, statistically significant improvements in participants' attitudes, knowledge, and self-confidence between the start and end of course (p < .001). The long-term outcomes of training and the implementation of learning, however, remain uncertain.
MeSH term(s)	Adult ; Child ; Child Abuse/prevention & control ; Cooperative Behavior ; Domestic Violence/prevention & control ; England ; Female ; Health Knowledge, Attitudes, Practice ; Humans ; Male ; Professional Competence ; Self Efficacy ; Self Report ; Social Work/education ; Teaching
Language	English
Publishing date	2013-11
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2031375-5
ISSN	1552-8448 ; 1077-8012
ISSN (online)	1552-8448
ISSN	1077-8012
DOI	10.1177/1077801213513857
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Article ; Online: Neighbourhood incidence rate of paediatric dental extractions under general anaesthetic in South West England.

Lucas, P J / Patsios, D / Walls, K / Neville, P / Harwood, P / Williams, J G / Sandy, J

British dental journal

2018 Volume 224, Issue 3, Page(s) 169–176

Abstract: Introduction Extraction of decayed teeth is the most common reason for UK children aged 5-9 years to receive a general anaesthetic. Inequalities in oral health are well recognised, but is under-explored in dental general anaesthesia (DGA).Methods ... ...

Abstract	Introduction Extraction of decayed teeth is the most common reason for UK children aged 5-9 years to receive a general anaesthetic. Inequalities in oral health are well recognised, but is under-explored in dental general anaesthesia (DGA).Methods Secondary analysis of routinely collected data from three local authorities in South West England was used to assess: 1) dental activities recorded for children <18 years attending NHS general dental practitioners (GDP); 2) the incidence rate of DGA and disease severity among <16-year-olds; and 3) individual and neighbourhood factors associated with higher rates of child DGA, and greater severity of disease.Results Among 208,533 GDP appointments, rates of preventive action were low where 1/7 included fluoride varnish but 1/5 included permanent fillings. The incidence rate of DGA was 6.6 admissions for every 1,000 children, rising to 12.4/1,000 among 5-9-year-olds. A total of 86 (7.6%) children had previously received a DGA at the same hospital. Area deprivation was strongly associated with higher rates of DGA, but rates of DGA remained high in less deprived areas. No associations were observed between number of teeth removed and socio-economic status.Conclusion Too many children are receiving DGA, and too few preventive actions are recorded by GDPs. Area-based inequalities in DGA were apparent, but wealthy areas also experienced substantial childhood dental decay.
MeSH term(s)	Anesthesia, Dental ; Anesthesia, General ; Anesthetics, General ; Child ; Child, Preschool ; Dental Caries ; England ; Female ; Healthcare Disparities ; Humans ; Incidence ; Male ; Tooth Extraction
Chemical Substances	Anesthetics, General
Language	English
Publishing date	2018-02-08
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	218090-x
ISSN	1476-5373 ; 0007-0610
ISSN (online)	1476-5373
ISSN	0007-0610
DOI	10.1038/sj.bdj.2018.77
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Article: Longâterm performance of a membrane bioreactor treating table olive processing wastewater

Patsios, Sotiris I / Anastasios J Karabelas / Emmanouil H Papaioannou

Journal of chemical technology and biotechnology. 2016 Aug., v. 91, no. 8

2016

Abstract	BACKGROUND: Table olive processing wastewater (TOPW) is a seriously polluting and difficult to treat effluent, characterized by widely fluctuating pH and salinity, as well as high concentrations of organic matter and polyphenols. This systematic longâterm study in a laboratoryâscale pilot demonstrates that membrane bioreactor (MBR) technology is effective in substantially bioâdegrading TOPW. RESULTS: After implementation of an appropriate protocol of active biomass acclimatization/proliferation, the MBR pilot was operated for 6 months with real TOPW effluent, under various operating conditions. Total organic carbon (TOC) and total polyphenol (TPh) compounds removal efficiencies were very high with mean values 91.5 and 82.8%, respectively; nutrient (N and P) removal was also satisfactory. The membrane exhibited stable performance at moderate biomass concentration, with a tendency to deteriorate at higher biomass concentration. Fouled membrane permeability could be fully restored by implementing the usual chemical cleaning protocols. CONCLUSIONS: Despite the high percentage TOC and TPh removal, the MBR effluent requires final postâtreatment to remove a yellowish tint and further reduce its organic content, depending on local discharge standards. The MBR can serve as the basic treatment process in an integrated scheme for TOPW management, which needs additional R&D to further develop and optimize. Â© 2015 Society of Chemical Industry
Keywords	acclimation ; biomass ; bioreactors ; carbon ; cleaning ; membrane permeability ; olives ; organic matter ; pH ; polyphenols ; salinity ; wastewater
Language	English
Dates of publication	2016-08
Size	p. 2253-2262.
Publishing place	John Wiley & Sons, Ltd
Document type	Article
Note	JOURNAL ARTICLE
ZDB-ID	1479465-2
ISSN	1097-4660 ; 0268-2575
ISSN (online)	1097-4660
ISSN	0268-2575
DOI	10.1002/jctb.4811
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Adjuvant lung resection in the management of nontuberculous mycobacterial lung infection: A retrospective matched cohort study.

Aznar, María Luisa / Zubrinic, Marijana / Siemienowicz, Miranda / Hashimoto, Kohei / Brode, Sarah Kathleen / Mehrabi, Mahtab / Patsios, Demetris / Keshavjee, Shafique / Marras, Theodore Konstantine

Respiratory medicine

2018 Volume 142, Page(s) 1–6

Abstract: Background and objectives: Lung resection in patients with nontuberculous mycobacterial pulmonary disease (NTM-PD) is considered when medical therapy alone fails to provide long term control. Data regarding comparative and long-term outcomes are limited. ...

Abstract	Background and objectives: Lung resection in patients with nontuberculous mycobacterial pulmonary disease (NTM-PD) is considered when medical therapy alone fails to provide long term control. Data regarding comparative and long-term outcomes are limited. We aimed to review indications and outcomes of adjuvant lung resection for NTM-PD compared with controls. Methods: We retrospectively studied 27 surgically treated patients, matched 1:1 for age, sex, NTM species, and radiologic pattern of disease, with control patients treated exclusively with antibiotics. Results: In the surgical group, the median (IQR) age was 55 (49-61) years and 74.1% were female. Eighteen patients had Mycobacterium avium complex, and 9 had M. xenopi. Operations included 8 pneumonectomies, 20 lobectomies, one segmentectomy and one lobectomy plus segmentectomy. Post-surgical complications occurred in 6 patients (20%), including 2 acute respiratory distress syndrome, 1 bronchopleural fistula, 1 pericardial tamponade, and 2 empyema. Complications were more common among patients operated upon for progressive disease despite medical therapy (OR 10, p = 0.025). Of 24 matched pairs followed for ≥1 year, sustained culture conversion was observed in 21 (87.5%) patients in the surgical group and in 11 (45.8%) patients in the non-surgical group (RR 2.36, 95%CI 1.37-4.03, p = 0.002). Median (IQR) percentage of follow-up time on antibiotics was 14% (0-100%) in the surgical group and 83% (10.8%-100%) in the non-surgical group (p = 0.195) during a median (IQR) follow-up of 16 (2-36) months. Conclusions: NTM-PD patients who underwent adjuvant lung resection experienced significant morbidity and more frequently achieved sputum culture conversion. Long term antibiotic requirements may have been reduced.
MeSH term(s)	Anti-Bacterial Agents/administration & dosage ; Cohort Studies ; Combined Modality Therapy ; Female ; Follow-Up Studies ; Humans ; Male ; Middle Aged ; Mycobacterium Infections, Nontuberculous/therapy ; Pneumonectomy/methods ; Retrospective Studies ; Time Factors ; Treatment Outcome ; Tuberculosis, Pulmonary/therapy
Chemical Substances	Anti-Bacterial Agents
Language	English
Publishing date	2018-07-09
Publishing country	England
Document type	Journal Article
ZDB-ID	1003348-8
ISSN	1532-3064 ; 0954-6111
ISSN (online)	1532-3064
ISSN	0954-6111
DOI	10.1016/j.rmed.2018.07.003
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Article ; Online: Need for comprehensive management of frailty at an individual level: European perspective from the advantage joint action on frailty.

Gabrovec, Branko / Antoniadou, Eleftheria / Soleymani, Dagmar / Kadalska, Ewa / Carriazo, Ana Maria / Samaniego, Luz López / Csizmadia, Péter / Hendry, Anne / Bacaicoa, Olatz Albaina / Jelenc, Marjetka / Selak, Špela / Patsios, Demi / Stolakis, Konstantinos / Mentis, Manolis / Papathanasopoulos, Fotis / Panagiotopoulos, Elias / Mañas, Leocadia Rodríguez

Journal of rehabilitation medicine

2020 Volume 52, Issue 6, Page(s) jrm00075

Abstract: ... Multicomponent exercise programmes, adequate protein and vitamin D intake, when insufficient, and reduction ...

Abstract	Objectives: ADVANTAGE Joint Action is a large collaborative project co-founded by the European Commission and its Member States to build a common understanding of frailty for Member States on which to base a common management approach for older people who are frail or at risk of developing frailty. One of the key objectives of the project is presented in this paper; how to manage frailty at the individual level. Methods: A systematic review of the literature was conducted, including grey literature and good practices when possible. Results: The management of frailty should be directed towards comprehensive and holistic treatment in multiple and related fields. Prevention requires a multifaceted approach addressing factors that have resonance across the individual's life course. Comprehensive geriatric assessment to diagnose the condition and plan a personalized multidomain treatment increases better outcomes. Multicomponent exercise programmes, adequate protein and vitamin D intake, when insufficient, and reduction in polypharmacy and inadequate prescription, are the most effective strategies found in the literature to manage frailty effectively. Conclusion: Frailty can be effectively prevented and managed with a multidomain intervention strategy based on comprehensive geriatric assessment.
MeSH term(s)	Aged ; Aged, 80 and over ; Europe ; Female ; Frailty ; Geriatric Assessment/methods ; Humans ; Male
Language	English
Publishing date	2020-06-30
Publishing country	Sweden
Document type	Journal Article
ZDB-ID	2039427-5
ISSN	1651-2081 ; 1651-2235 ; 0891-060X ; 1650-1977
ISSN (online)	1651-2081 ; 1651-2235
ISSN	0891-060X ; 1650-1977
DOI	10.2340/16501977-2687
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Article ; Online: Impact of tumour thickness on survival after radical radiation and surgery in malignant pleural mesothelioma.

de Perrot, Marc / Dong, Zhi / Bradbury, Penelope / Patsios, Demetris / Keshavjee, Shaf / Leighl, Natasha B / Hope, Andrew / Feld, Ronald / Cho, John

The European respiratory journal

2017 Volume 49, Issue 3

Abstract: Tumour thickness was assessed to determine if this parameter could refine patients' selection for multimodality therapy in malignant pleural mesothelioma.We reviewed 65 consecutive treatment-naïve malignant pleural mesothelioma patients undergoing ... ...

Abstract	Tumour thickness was assessed to determine if this parameter could refine patients' selection for multimodality therapy in malignant pleural mesothelioma.We reviewed 65 consecutive treatment-naïve malignant pleural mesothelioma patients undergoing surgery for mesothelioma after radiation therapy (SMART). Total tumour thickness was determined by measuring the maximal thickness on nine predefined sectors on the chest wall, mediastinum and diaphragm.After a median follow-up of 19 months, 40 patients (62%) developed recurrence and 36 died (55%). Total tumour thickness, ranging between 2.4 and 21 cm (median 6.9 cm), correlated with tumour volume (p<0.0001, R
MeSH term(s)	Adult ; Aged ; Aged, 80 and over ; Canada ; Combined Modality Therapy ; Female ; Humans ; Lung Neoplasms/mortality ; Lung Neoplasms/pathology ; Lung Neoplasms/therapy ; Male ; Mesothelioma/mortality ; Mesothelioma/pathology ; Mesothelioma/therapy ; Mesothelioma, Malignant ; Middle Aged ; Neoplasm Recurrence, Local/epidemiology ; Neoplasm Staging ; Patient Selection ; Pleural Neoplasms/mortality ; Pleural Neoplasms/pathology ; Pleural Neoplasms/therapy ; Survival Analysis ; Treatment Outcome
Language	English
Publishing date	2017-03-15
Publishing country	England
Document type	Journal Article
ZDB-ID	639359-7
ISSN	1399-3003 ; 0903-1936
ISSN (online)	1399-3003
ISSN	0903-1936
DOI	10.1183/13993003.01428-2016
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