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Article: Survey of feline giardiasis by ELISA test in Italy.

Papini, R / Giuliani, G / Gorini, G / Cardini, G

2007 Volume 31, Issue 3, Page(s) 297–303

MeSH term(s)	Animals ; Antigens, Protozoan/analysis ; Cat Diseases/epidemiology ; Cat Diseases/parasitology ; Cats ; Enzyme-Linked Immunosorbent Assay/veterinary ; Feces/parasitology ; Female ; Giardia/isolation & purification ; Giardiasis/epidemiology ; Giardiasis/parasitology ; Giardiasis/veterinary ; Intestinal Diseases, Parasitic/epidemiology ; Intestinal Diseases, Parasitic/parasitology ; Intestinal Diseases, Parasitic/veterinary ; Italy/epidemiology ; Male ; Prevalence
Chemical Substances	Antigens, Protozoan
Language	English
Publishing date	2007-04
Publishing country	Netherlands
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	406735-6
ISSN	1573-7446 ; 0165-7380
ISSN (online)	1573-7446
ISSN	0165-7380
DOI	10.1007/s11259-006-3428-8
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Article ; Audio / Video: Survey of feline giardiasis by ELISA test in Italy

Papini, R / Giuliani, G / Gorini, G / Cardini, G

Veterinary research communications. 2007 Apr., v. 31, no. 3

2007

Keywords	cats ; cat diseases ; Giardia ; animal pathogens ; giardiasis ; disease surveillance ; diagnostic techniques ; disease detection ; disease diagnosis ; enzyme-linked immunosorbent assay ; polymerase chain reaction ; antigens ; molecular weight ; glycoproteins ; trophozoites ; cysts (developmental stages) ; signs and symptoms (animals and humans) ; Italy
Language	English
Dates of publication	2007-04
Size	p. 297-303.
Document type	Article ; Audio / Video
ZDB-ID	406735-6
ISSN	1573-7446 ; 0165-7380
ISSN (online)	1573-7446
ISSN	0165-7380
Database	NAL-Catalogue (AGRICOLA)

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Z 3158: Show issues

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Article ; Online: Porto-spleno-mesenteric venous thrombosis after elective splenectomy: a retrospective cohort study.

Baldari, Ludovica / Boni, Luigi / Giuliani, Beatrice / Cassinotti, Elisa

Frontiers in immunology

2023 Volume 14, Page(s) 1216283

Abstract: Background: Elective splenectomy is the main treatment for a wide range of haematological diseases. Porto-spleno-mesenteric venous thrombosis represents one of the most severe complications of this procedure. The aim of this study was to evaluate risk ... ...

Abstract	Background: Elective splenectomy is the main treatment for a wide range of haematological diseases. Porto-spleno-mesenteric venous thrombosis represents one of the most severe complications of this procedure. The aim of this study was to evaluate risk factors associated with development of porto-spleno-mesenteric venous thrombosis after elective splenectomy. Methods: All cases of elective splenectomy carried out from April 1 Results: Twenty-two patients (10 women, 12 men) underwent splenectomy during the study period. Indications were: immune thrombocytopenia (n: 6), myeloproliferative disorder (n: 6), hereditary spherocytosis (n: 4), thalassemia (n: 1), lymphoma (n: 1), leukaemia (n: 1), other malignancies (n: 3). Six patients developed porto-spleno-mesenteric venous thrombosis and only 2 of them were symptomatic. Patients were treated with anticoagulation therapy with complete resolution. Analysis identified three main factors associated with thrombosis: spleen diameter (p = 0.03), myeloproliferative disorder (p = 0.02), intraoperative platelet transfusion (p = 0.002) and intraoperative red blood cells transfusion (p = 0.009). Conclusion: Standardized postoperative screening allows prompt diagnosis and treatment of porto-spleno-mesenteric venous thrombosis even in asymptomatic cases. Patient with splenomegaly and affected by myeloproliferative disorder have a greater risk to develop this complication.
MeSH term(s)	Male ; Humans ; Female ; Spleen ; Splenectomy/adverse effects ; Splenectomy/methods ; Retrospective Studies ; Venous Thrombosis/diagnostic imaging ; Venous Thrombosis/epidemiology ; Venous Thrombosis/etiology ; Thrombosis/etiology ; Myeloproliferative Disorders/etiology
Language	English
Publishing date	2023-10-20
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2606827-8
ISSN	1664-3224 ; 1664-3224
ISSN (online)	1664-3224
ISSN	1664-3224
DOI	10.3389/fimmu.2023.1216283
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Article: Human rights and corporate social responsibility in developing countries’ industrial clusters

Giuliani, Elisa

Journal of business ethics : JOBE Vol. 133, No. 1 , p. 39-54

2016 Volume 133, Issue 1, Page(s) 39–54

Author's details	Elisa Giuliani
Keywords	Human rights ; Corporate social responsibility (CSR) ; Industrial clusters ; Developing countries
Language	English
Publisher	Springer
Publishing place	Dordrecht
Document type	Article
ZDB-ID	868017-6 ; 1478688-6
ISSN	1573-0697 ; 0167-4544
ISSN (online)	1573-0697
ISSN	0167-4544
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Article: Italian industrial districts today

Giuliani, Elisa / Rabellotti, Roberta

Local clusters in global value chains : linking actors and territories through manufacturing and innovation , p. 21-32

between decline and openness to global value chains

2018 , Page(s) 21–32

Author's details	Elisa Giuliani and Roberta Rabellotti
Language	English
Publisher	Routledge
Publishing place	London
Document type	Article
ISBN	978-1-138-74286-4 ; 1-138-74286-4
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Article ; Online: Spreading Senescent Cells' Burden and Emerging Therapeutic Targets for Frailty.

Marcozzi, Serena / Bigossi, Giorgia / Giuliani, Maria Elisa / Lai, Giovanni / Giacconi, Robertina / Piacenza, Francesco / Malavolta, Marco

Cells

2023 Volume 12, Issue 18

Abstract: The spreading of senescent cells' burden holds profound implications for frailty, prompting the exploration of novel therapeutic targets. In this perspective review, we delve into the intricate mechanisms underlying senescent cell spreading, its ... ...

Abstract	The spreading of senescent cells' burden holds profound implications for frailty, prompting the exploration of novel therapeutic targets. In this perspective review, we delve into the intricate mechanisms underlying senescent cell spreading, its implications for frailty, and its therapeutic development. We have focused our attention on the emerging age-related biological factors, such as microbiome and virome alterations, elucidating their significant contribution to the loss of control over the accumulation rate of senescent cells, particularly affecting key frailty domains, the musculoskeletal system and cerebral functions. We believe that gaining an understanding of these mechanisms could not only aid in elucidating the involvement of cellular senescence in frailty but also offer diverse therapeutic possibilities, potentially advancing the future development of tailored interventions for these highly diverse patients.
MeSH term(s)	Humans ; Frailty ; Age Factors ; Cellular Senescence ; Microbiota
Language	English
Publishing date	2023-09-15
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2661518-6
ISSN	2073-4409 ; 2073-4409
ISSN (online)	2073-4409
ISSN	2073-4409
DOI	10.3390/cells12182287
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Article ; Online: Season specific influence of projected ocean changes on the response to cadmium of stress-related genes in Mytilus galloprovincialis.

Giuliani, Maria Elisa / Filippini, Giulia / Nardi, Alessandro

Marine environmental research

2020 Volume 162, Page(s) 105091

Abstract: Anthropogenic inputs of carbon dioxide in the atmosphere are driving ocean warming and acidification. The potential threat represented by these changes for marine species could be amplified in coastal areas, characterized by higher levels of pollutants. ... ...

Abstract	Anthropogenic inputs of carbon dioxide in the atmosphere are driving ocean warming and acidification. The potential threat represented by these changes for marine species could be amplified in coastal areas, characterized by higher levels of pollutants. In addition, temperate organisms may exhibit a different seasonal tolerance to stressors influenced by fluctuations of environmental and physiological factors. In this study, Mediterranean mussels Mytilus galloprovincialis collected both in summer and winter were exposed to combinations of two temperatures (SST, seasonal surface temperature and SST+5 °C) and two levels of pH (8.20 and 7.40) in clean or cadmium contaminated seawater (20 μg/L Cd). mRNA levels of genes related to metal-induced stress response were investigated, including metallothionein mt-20, heat-shock protein hsp70, superoxide dismutase Cu/Zn-sod, catalase cat, glutathione peroxidase gpx1 and glutathione S-transferase gst-pi. To further elucidate if tissues with different physiological roles could exhibit different responsiveness, such analyses were carried out in digestive gland and in gills of exposed mussels. mt-20 mRNA increase after Cd-exposure was higher in the digestive gland than in the gills, with few modulations by temperature or pH only in the latter. Acidification, alone or in combination with other stressors, increased hsp70 mRNA, with seasonal- and tissue-specificities (higher in summer and in digestive gland). Among antioxidants, gpx1 mRNA was affected by Cd in both tissues and seasons, with further modulations due to pH and temperature variation tissue- and season-specific; in winter the combination of Cd, warming and acidification affected Cu/Zn-sod both in digestive gland and gills and cat only in gills, while weak seasonal variations were observed for gst-pi transcripts only in digestive gland. The overall results highlighted the importance of considering seasonality and responsiveness of different tissues to predict the effects of sudden changes in environmental parameters on responsiveness to and toxicity of chemicals in marine coastal organisms.
MeSH term(s)	Animals ; Biomarkers/metabolism ; Cadmium/toxicity ; Gills/chemistry ; Metallothionein/metabolism ; Mytilus/genetics ; Mytilus/metabolism ; Oceans and Seas ; Oxidative Stress ; Seasons ; Water Pollutants, Chemical/analysis
Chemical Substances	Biomarkers ; Water Pollutants, Chemical ; Cadmium (00BH33GNGH) ; Metallothionein (9038-94-2)
Language	English
Publishing date	2020-07-29
Publishing country	England
Document type	Journal Article
ZDB-ID	1502505-6
ISSN	1879-0291 ; 0141-1136
ISSN (online)	1879-0291
ISSN	0141-1136
DOI	10.1016/j.marenvres.2020.105091
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Article ; Online: Associations between continuous glucose monitoring (CGM) metrics and psycholinguistic measures: a correlational study.

Marchini, Francesco / Caputo, Andrea / Convertino, Alessio / Giuliani, Chiara / Bitterman, Olimpia / Pitocco, Dario / Fornengo, Riccardo / Lovati, Elisabetta / Forte, Elisa / Sciacca, Laura / Napoli, Angela

Acta diabetologica

2024

Abstract: Aim: Recently, the relationship between diabetes and mental health has been widely studied. With the advent of continuous glucose monitoring (CGM), some researchers have been interested in exploring the association between glucose-related metrics and ... ...

Abstract	Aim: Recently, the relationship between diabetes and mental health has been widely studied. With the advent of continuous glucose monitoring (CGM), some researchers have been interested in exploring the association between glucose-related metrics and psychological aspects. These studies have primarily relied on self-report questionnaires which present some limitations. Therefore, the present multicenter study aims at testing potential associations between CGM metrics and affective processes derived from narratives about using a CGM sensor. Methods: An exploratory correlational design was used. Fifty-eight adults with type 1 diabetes using CGM were enrolled and invited to complete an online survey, where they replied to an open-ended question regarding their personal experience with the CGM sensor. Texts derived from the answers were analyzed through Linguistic Inquiry and Word Count, a widely used text analysis tool that can automatically identify and quantify linguistic patterns related to various psychological dimensions. Psycholinguistic measures were correlated with CGM metrics. Results: Higher levels of sadness/depression correlated with lower %TIR (r = - 339; p < .01) and higher %TAR (r = .342; p < .01). Conclusions: The study highlights the relationship between CGM metrics and psychological variables derived from patients' narratives. In particular, it is possible to hypothesize a positive role of %TIR in reducing depressive feelings in individuals with diabetes, as well as a negative role of depressive feelings in achieving desirable CGM outcomes. Additionally, there is a potential role of glycemic variability, particularly hyperglycemia, in the expression of depressive and sad feelings, which has been less studied compared to the effects of hypoglycemia.
Language	English
Publishing date	2024-03-16
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1097676-0
ISSN	1432-5233 ; 0940-5429
ISSN (online)	1432-5233
ISSN	0940-5429
DOI	10.1007/s00592-024-02244-x
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Article ; Online: Subcellular effects and lipid metabolism alterations in the gilthead seabream Sparus aurata fed on ovatoxins-contaminated mussels.

Giuliani, Maria Elisa / Bacchiocchi, Simone / Accoroni, Stefano / Siracusa, Melania / Campacci, Debora / Notarstefano, Valentina / Mezzelani, Marica / Piersanti, Arianna / Totti, Cecilia / Benedetti, Maura / Regoli, Francesco / Gorbi, Stefania

Chemosphere

2024 Volume 352, Page(s) 141413

Abstract: The marine microalgae Ostreopsis cf. ovata are a well-known producer of palytoxin (PlTXs) analogues, i.e. ovatoxins (OVTXs) among others, which arouse concern for animal and human health. Both in field and laboratory studies, presence of OVTXs, detected ... ...

Abstract	The marine microalgae Ostreopsis cf. ovata are a well-known producer of palytoxin (PlTXs) analogues, i.e. ovatoxins (OVTXs) among others, which arouse concern for animal and human health. Both in field and laboratory studies, presence of OVTXs, detected in species directly feeding on O. cf. ovata, was frequently correlated with impairment on organisms' physiology, development and behaviour, while similar knowledge is still lacking for animals feeding on contaminated preys. In this study, transfer and toxicity of OVTXs were evaluated in an exposure experiment, in which gilthead seabream Sparus aurata was fed with bivalve mussel Mytilus galloprovincialis, contaminated by a toxic strain of O. cf. ovata. Mussels exposed to O. cf. ovata for 21 days accumulated meanly 188 ± 13 μg/kg OVTXs in the whole tissues. Seabreams fed with OVTX-contaminated mussels started to reject the food after 6 days of contaminated diet. Although no detectable levels of OVTXs were measured in muscle, liver, gills and gastro-intestinal tracts, the OVTX-enriched diet induced alterations of lipid metabolism in seabreams livers, displaying a decreased content of total lipid and fatty acid, together with overexpression of fatty acid biosynthetic genes, downregulation of β-oxidation genes and modulation of several genes related to lipid transport and regulation. Results from this study would suggest the hypothesis that OVTXs produced by O. cf. ovata may not be subject to bioaccumulation in fish fed on contaminated preys, being however responsible of significant biological effects, with important implications for human consumption of seafood products.
MeSH term(s)	Animals ; Humans ; Sea Bream ; Marine Toxins/toxicity ; Lipid Metabolism ; Seafood ; Dinoflagellida/genetics ; Mytilus ; Fatty Acids ; Lipids
Chemical Substances	Marine Toxins ; Fatty Acids ; Lipids
Language	English
Publishing date	2024-02-07
Publishing country	England
Document type	Journal Article
ZDB-ID	120089-6
ISSN	1879-1298 ; 0045-6535 ; 0366-7111
ISSN (online)	1879-1298
ISSN	0045-6535 ; 0366-7111
DOI	10.1016/j.chemosphere.2024.141413
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Article: Replicative senescence and high glucose induce the accrual of self-derived cytosolic nucleic acids in human endothelial cells.

Ramini, Deborah / Giuliani, Angelica / Kwiatkowska, Katarzyna Malgorzata / Guescini, Michele / Storci, Gianluca / Mensà, Emanuela / Recchioni, Rina / Xumerle, Luciano / Zago, Elisa / Sabbatinelli, Jacopo / Santi, Spartaco / Garagnani, Paolo / Bonafè, Massimiliano / Olivieri, Fabiola

Cell death discovery

2024 Volume 10, Issue 1, Page(s) 184

Abstract: Recent literature shows that loss of replicative ability and acquisition of a proinflammatory secretory phenotype in senescent cells is coupled with the build-in of nucleic acids in the cytoplasm. Its implication in human age-related diseases is under ... ...

Abstract	Recent literature shows that loss of replicative ability and acquisition of a proinflammatory secretory phenotype in senescent cells is coupled with the build-in of nucleic acids in the cytoplasm. Its implication in human age-related diseases is under scrutiny. In human endothelial cells (ECs), we assessed the accumulation of intracellular nucleic acids during in vitro replicative senescence and after exposure to high glucose concentrations, which mimic an in vivo condition of hyperglycemia. We showed that exposure to high glucose induces senescent-like features in ECs, including telomere shortening and proinflammatory cytokine release, coupled with the accrual in the cytoplasm of telomeres, double-stranded DNA and RNA (dsDNA, dsRNA), as well as RNA:DNA hybrid molecules. Senescent ECs showed an activation of the dsRNA sensors RIG-I and MDA5 and of the DNA sensor TLR9, which was not paralleled by the involvement of the canonical (cGAS) and non-canonical (IFI16) activation of the STING pathway. Under high glucose conditions, only a sustained activation of TLR9 was observed. Notably, senescent cells exhibit increased proinflammatory cytokine (IL-1β, IL-6, IL-8) production without a detectable secretion of type I interferon (IFN), a phenomenon that can be explained, at least in part, by the accumulation of methyl-adenosine containing RNAs. At variance, exposure to exogenous nucleic acids enhances both IL-6 and IFN-β1 expression in senescent cells. This study highlights the accrual of cytoplasmic nucleic acids as a marker of senescence-related endothelial dysfunction, that may play a role in dysmetabolic age-related diseases.
Language	English
Publishing date	2024-04-20
Publishing country	United States
Document type	Journal Article
ISSN	2058-7716
ISSN	2058-7716
DOI	10.1038/s41420-024-01954-z
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