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  1. Article ; Online: A Phase III Clinical Study of the Efficacy and Safety of Botulinum Toxin Type A (MASPORT) with DYSPORT for the Treatment of Glabellar Lines.

    Hedayat, Kamand / Ehsani, Amir H

    Aesthetic plastic surgery

    2024  Volume 48, Issue 3, Page(s) 324–332

    Abstract: Background: Botulinum toxin type A is a widely used treatment of facial wrinkles. The objective of this study was to compare the efficacy and safety of a new botulinum toxin type A (Masport [abobotulinum toxin A], MasoonDarou Co) with DYSPORT: Methods! ...

    Abstract Background: Botulinum toxin type A is a widely used treatment of facial wrinkles. The objective of this study was to compare the efficacy and safety of a new botulinum toxin type A (Masport [abobotulinum toxin A], MasoonDarou Co) with DYSPORT
    Methods: 262 subjects with moderate-to-severe glabellar lines received either a fixed dose of 50 units of MASPORT
    Results: According to the investigator evaluations, the responder rate at maximum frown were 94.5% for MASPORT and 95.6% for DYSPORT group on day 30 and at rest were 85.45% and 85.68% for MASPORT and DYSPORT group, respectively. According to the subject self-assessment, the proportion of responders in MASPORT group at day 30 was 95.28% versus 97.04% for DYSPORT group. No serious drug related adverse effect was recorded in either study groups, and the rates of adverse effects were similar for both groups.
    Conclusion: Abobotulinum toxin A [MASPORT] is equally safe and effective as commercial product [DYSPORT] for the treatment of glabellar lines with the dose of 50 units, up to 120 days.
    Level of evidence i: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .
    MeSH term(s) Humans ; Botulinum Toxins, Type A/adverse effects ; Treatment Outcome ; Forehead ; Injections, Intramuscular ; Skin Aging ; Drug-Related Side Effects and Adverse Reactions ; Neuromuscular Agents/adverse effects ; Double-Blind Method
    Chemical Substances abobotulinumtoxinA (EC 3.4.24.69) ; Botulinum Toxins, Type A (EC 3.4.24.69) ; Neuromuscular Agents
    Language English
    Publishing date 2024-01-17
    Publishing country United States
    Document type Clinical Trial, Phase III ; Journal Article
    ZDB-ID 532791-x
    ISSN 1432-5241 ; 0364-216X
    ISSN (online) 1432-5241
    ISSN 0364-216X
    DOI 10.1007/s00266-023-03766-5
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  2. Article: H. pylori infection and reflux oesophagitis: a case-control study.

    Masjedizadeh, Rahim / Hajiani, Eskandar / Moezardalan, Koorosh / Samie, Saeed / Ehsani-Ardakani, Mohammad-Javad / Daneshmand, Ali / Zali, Mohammad-Reza

    World journal of gastroenterology

    2005  Volume 12, Issue 35, Page(s) 5658–5662

    Abstract: Aim: To examine the relationship between H. pylori and gastro-oesophageal reflux disease (GORD ... compared with 49 age-sex matched controls. Diagnosis of H. pylori was made by gastric mucosal biopsy and ... Sydney system was used to report histopathological changes.: Results: The frequency of H. pylori ...

    Abstract Aim: To examine the relationship between H. pylori and gastro-oesophageal reflux disease (GORD) in Iran.
    Methods: In this study 51 GORD patients (referred to endoscopy at Taleghani hospital) were compared with 49 age-sex matched controls. Diagnosis of H. pylori was made by gastric mucosal biopsy and rapid urease test (positive if the result of one or both diagnostic methods was positive). Updated Sydney system was used to report histopathological changes.
    Results: The frequency of H. pylori infection based on rapid urease test and histology was 88.2% (45) in patients and 77.6% (38) in controls, which showed no significant difference. The frequency of H. pylori infection was significantly higher in the antrum than in the corpus and cardia. The mean activity, inflammation, and gastritis scores were also higher in the antrum of patients than in the antrum of controls. The mean scores were significantly higher in the corpus of controls than in the corpus of patients. Diffuse active gastritis was observed in a significantly larger number of controls, while the frequency of diffuse chronic gastritis was higher in patients. There was no significant difference in the frequency of other histological findings between patients and controls.
    Conclusion: H. pylori infection cannot prevent GORD in this region.
    MeSH term(s) Adolescent ; Adult ; Aged ; Aged, 80 and over ; Cardia/microbiology ; Cardia/pathology ; Case-Control Studies ; Esophagitis, Peptic/epidemiology ; Esophagitis, Peptic/microbiology ; Esophagitis, Peptic/pathology ; Esophagus/microbiology ; Esophagus/pathology ; Female ; Gastric Mucosa/microbiology ; Gastric Mucosa/pathology ; Helicobacter Infections/complications ; Helicobacter Infections/epidemiology ; Helicobacter Infections/pathology ; Helicobacter pylori ; Humans ; Iran/epidemiology ; Male ; Middle Aged ; Pyloric Antrum/microbiology ; Pyloric Antrum/pathology
    Language English
    Publishing date 2005-07-20
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2185929-2
    ISSN 2219-2840 ; 1007-9327
    ISSN (online) 2219-2840
    ISSN 1007-9327
    DOI 10.3748/wjg.v12.i35.5658
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  3. Article ; Online: Stimuli-Responsive Electrochemical Energy Storage Devices.

    Parsimehr, Hamidreza / Ehsani, Ali

    Chemical record (New York, N.Y.)

    2022  Volume 22, Issue 9, Page(s) e202200075

    Abstract: Electrochemical energy storage (EES) devices have been swiftly developed in recent years. Stimuli-responsive EES devices that respond to different external stimuli are considered the most advanced EES devices. The stimuli-responsive EES devices enhanced ... ...

    Abstract Electrochemical energy storage (EES) devices have been swiftly developed in recent years. Stimuli-responsive EES devices that respond to different external stimuli are considered the most advanced EES devices. The stimuli-responsive EES devices enhanced the performance and applications of the EES devices. The capability of the EES devices to respond to the various external stimuli due to produced advanced EES devices that distinguished the best performance and interactions in different situations. The stimuli-responsive EES devices have responsive behavior to different external stimuli including chemical compounds, electricity, photons, mechanical tensions, and temperature. All of these advanced responsiveness behaviors have originated from the functionality and specific structure of the EES devices. The multi-responsive EES devices have been recognized as the next generation of stimuli-responsive EES devices. There are two main steps in developing stimuli-responsive EES devices in the future. The first step is the combination of the economical, environmental, electrochemical, and multi-responsiveness priorities in an EES device. The second step is obtaining some advanced properties such as biocompatibility, flexibility, stretchability, transparency, and wearability in novel stimuli-responsive EES devices. Future studies on stimuli-responsive EES devices will be allocated to merging these significant two steps to improve the performance of the stimuli-responsive EES devices to challenge complicated situations.
    MeSH term(s) Temperature
    Language English
    Publishing date 2022-07-13
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2044646-9
    ISSN 1528-0691 ; 1527-8999
    ISSN (online) 1528-0691
    ISSN 1527-8999
    DOI 10.1002/tcr.202200075
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  4. Article ; Online: Transcranial direct current stimulation over dorsolateral prefrontal cortex improves postural stability in non-specific chronic low back pain patients with high fear of pain: A randomized sham-controlled trial.

    Ehsani, Fatemeh / Masoudi, Mona / Hedayati, Rozita / Jaberzadeh, Shapour

    The European journal of neuroscience

    2023  Volume 58, Issue 5, Page(s) 3315–3329

    Abstract: ... s in the sham group. Before, immediately, 24 h and 1 week after the interventions, postural ... shown in both a-tDCS and c-tDCS groups after interventions (immediately, 24 h and 1 week follow-up ...

    Abstract Deficits in postural stability in response to environmental challenges are seen in chronic low back pain (CLBP) patients with high fear of pain (HFP). Hence, it is essential to follow effective approaches to treat postural stability deficits and improve the health status of these patients. The current study aimed to compare the effects of cathodal and anodal transcranial direct current stimulation (c-tDCS and a-tDCS) over the left dorsolateral prefrontal cortex (DLPFC) on postural stability in non-specific CLBP patients with HFP. In this randomized clinical trial study, 75 patients were randomly assigned to left DLPFC a-tDCS, left DLPFC c-tDCS and sham stimulation groups (n = 25 in each group). All groups received a single-session 2 mA tDCS for 20 min, but the stimulation was slowly turned off after 30 s in the sham group. Before, immediately, 24 h and 1 week after the interventions, postural stability indices were assessed using a Biodex Balance System. A significant reduction in most indices was shown in both a-tDCS and c-tDCS groups after interventions (immediately, 24 h and 1 week follow-up) during static and dynamic postural tasks compared with the sham tDCS group (p < .01). In addition, some tests showed a significant difference between a-tDCS and c-tDCS (p < .05). The findings indicated positive effects of both a-tDCS and c-tDCS on the left DLPFC, with more efficacy of a-tDCS on postural stability in LBP patients with HFP.
    MeSH term(s) Humans ; Transcranial Direct Current Stimulation ; Dorsolateral Prefrontal Cortex ; Low Back Pain/therapy ; Research Design ; Fear ; Prefrontal Cortex/physiology ; Double-Blind Method
    Language English
    Publishing date 2023-07-31
    Publishing country France
    Document type Randomized Controlled Trial ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 645180-9
    ISSN 1460-9568 ; 0953-816X
    ISSN (online) 1460-9568
    ISSN 0953-816X
    DOI 10.1111/ejn.16090
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  5. Article ; Online: Aptamer-modified metal organic frameworks for measurement of food contaminants: a review.

    Tavassoli, Milad / Khezerlou, Arezou / Khalilzadeh, Balal / Ehsani, Ali / Kazemian, Hossein

    Mikrochimica acta

    2023  Volume 190, Issue 9, Page(s) 371

    Abstract: The measurement of food contaminants faces a great challenge owing to the increasing demand for safe food, increasing consumption of fast food, and rapidly changing patterns of human consumption. As different types of contaminants in food products can ... ...

    Abstract The measurement of food contaminants faces a great challenge owing to the increasing demand for safe food, increasing consumption of fast food, and rapidly changing patterns of human consumption. As different types of contaminants in food products can pose different levels of threat to human health, it is desirable to develop specific and rapid methods for their identification and quantification. During the past few years, metal-organic framework (MOF)-based materials have been extensively explored in the development of food safety sensors. MOFs are porous crystalline materials with tunable composition, dynamic porosity, and facile surface functionalization. The construction of high-performance biosensors for a range of applications (e.g., food safety, environmental monitoring, and biochemical diagnostics) can thus be promoted through the synergistic combination of MOFs with aptamers. Accordingly, this review article delineates recent innovations achieved for the aptamer-functionalized MOFs toward the detection of food contaminants. First, we describe the basic concepts involved in the detection of food contaminants in terms of the advantages and disadvantages of the commonly used analytical methods (e.g., DNA-based methods (PCR/real-time PCR/multiplex PCR/digital PCR) and protein-based methods (enzyme-linked immunosorbent assay/immunochromatography assay/immunosensor/mass spectrometry). Afterward, the progress in aptamer-functionalized MOF biosensors is discussed with respect to the sensing mechanisms (e.g., the role of MOFs as signal probes and carriers for loading signal probes) along with their performance evaluation (e.g., in terms of sensitivity). We finally discuss challenges and opportunities associated with the development of aptamer-functionalized MOFs for the measurement of food contaminants.
    MeSH term(s) Humans ; Metal-Organic Frameworks ; Biosensing Techniques ; Immunoassay ; Oligonucleotides ; Food, Processed
    Chemical Substances Metal-Organic Frameworks ; Oligonucleotides
    Language English
    Publishing date 2023-08-30
    Publishing country Austria
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 89-9
    ISSN 1436-5073 ; 0026-3672
    ISSN (online) 1436-5073
    ISSN 0026-3672
    DOI 10.1007/s00604-023-05937-2
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  6. Article ; Online: An ultrasensitive aptamer-based fluorescent on/off system for trace amount evaluation of Yersinia enterocolitica in food samples.

    Tavassoli, Milad / Khezerlou, Arezou / Hamishehkar, Hamed / Ehsani, Ali / Khalilzadeh, Balal

    Mikrochimica acta

    2023  Volume 190, Issue 7, Page(s) 253

    Abstract: An innovative aptamer labeled with 5-FAM has been developed with a high affinity for Yersinia enterocolitica (Y. enterocolitica) using graphene oxide (GO) as a quenching platform. The selectivity of the prepared system was evaluated in the presence of ... ...

    Abstract An innovative aptamer labeled with 5-FAM has been developed with a high affinity for Yersinia enterocolitica (Y. enterocolitica) using graphene oxide (GO) as a quenching platform. The selectivity of the prepared system was evaluated in the presence of common coexisted bacteria like Yersinia pseudotuberculosis, Staphylococcus aureus, Listeria monocytogenes, Escherichia coli, and Salmonella typhimurium. Some experimental factors like pH and stability were investigated. The results showed that in the absence of Y. enterocolitica, aptamer labeled with 5-FAM was bonded with GO, causing fluorescence to be relatively weak. After the addition of Y. enterocolitica, the aptamer is released from the GO surface and binds to the target bacteria, and significantly increases the fluorescence intensity with an excitation wavelength of 410 nm and an emission wavelength of 530 nm. After optimizing all conditions, the system exhibited a wide linear response for Y. enterocolitica in the concentration range 10 to 1.0 × 10
    MeSH term(s) Yersinia enterocolitica ; Yersinia pseudotuberculosis ; Limit of Detection ; Salmonella typhimurium ; Oligonucleotides ; Escherichia coli
    Chemical Substances Oligonucleotides
    Language English
    Publishing date 2023-06-07
    Publishing country Austria
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 89-9
    ISSN 1436-5073 ; 0026-3672
    ISSN (online) 1436-5073
    ISSN 0026-3672
    DOI 10.1007/s00604-023-05820-0
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  7. Article: Anabolic-androgenic anabolic steroids as a probable risk factor for hepatoblastoma in infants.

    Malekiantaghi, Armen / Shabani-Mirzaee, Hosein / Ehsani, MohammadAli / Eftekhari, Kambiz

    Clinical case reports

    2023  Volume 11, Issue 7, Page(s) e7676

    Abstract: Key clinical message: The etiology of hepatoblastoma (HB) is still unknown; several risk factors have been identified. The only risk factor for the development of HB in presented case was the child's father using anabolic androgenic steroids. It may be ... ...

    Abstract Key clinical message: The etiology of hepatoblastoma (HB) is still unknown; several risk factors have been identified. The only risk factor for the development of HB in presented case was the child's father using anabolic androgenic steroids. It may be a risk factor for developing HB in their children.
    Abstract: HB is the most common primary liver cancer in children. Its etiology is still unclear. The patient's father's use of androgenic anabolic steroids could be a risk factor for developing HB in his child. A 14-month-old girl was hospitalized with intermittent fever, severe abdominal distention, and anorexia. On initial examination, she was cachectic and pale. There were two hemangioma-like skin lesions in the back. Huge hepatomegaly was found and the ultrasound showed a hepatic hemangioma. The possibility of malignancy was considered due to the severe enlargement of the liver and the increased levels of the alpha-fetoprotein. An abdominopelvic CT scan was performed and finally, the diagnosis of HB was confirmed by pathology. There was no history of congenital anomalies or risk factors for HB.Also we did not find any risk factors in the mother's history either. The only positive finding in the father's history was the use of anabolic steroids for bodybuilding. Anabolic-androgenic anabolic steroids may be one of the possible causes of HB in children.
    Language English
    Publishing date 2023-07-10
    Publishing country England
    Document type Case Reports
    ZDB-ID 2740234-4
    ISSN 2050-0904
    ISSN 2050-0904
    DOI 10.1002/ccr3.7676
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  8. Article ; Online: Electrochemical energy storage electrodes from fruit biochar.

    Ehsani, Ali / Parsimehr, Hamidreza

    Advances in colloid and interface science

    2020  Volume 284, Page(s) 102263

    Abstract: This review investigates the electrochemical energy storage electrode (EESE) as the most important part of the electrochemical energy storage devices (EES) prepared from fruit-derived carbon. The EES devices include batteries, supercapacitors, and hybrid ...

    Abstract This review investigates the electrochemical energy storage electrode (EESE) as the most important part of the electrochemical energy storage devices (EES) prepared from fruit-derived carbon. The EES devices include batteries, supercapacitors, and hybrid devices that have various regular and advanced applications. The preparation of EESE from fruit wastes not only reduce the price of the electrode but also lead to enhance the electrochemical properties of the electrode. The astonishing results of fruits biochar at electrochemical analyses guarantee the performance of these electrodes as EESE. Also, using fruit waste as the precursor of the EESE due to protect the environment and reduce environmental pollutions.
    MeSH term(s) Charcoal/chemistry ; Electric Power Supplies ; Electrochemistry/instrumentation ; Electrodes ; Fruit/chemistry
    Chemical Substances biochar ; Charcoal (16291-96-6)
    Language English
    Publishing date 2020-09-07
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 210507-x
    ISSN 1873-3727 ; 0001-8686
    ISSN (online) 1873-3727
    ISSN 0001-8686
    DOI 10.1016/j.cis.2020.102263
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  9. Article ; Online: Electrochemical Energy Storage Electrodes via Citrus Fruits Derived Carbon: A Minireview.

    Ehsani, Ali / Parsimehr, Hamidreza

    Chemical record (New York, N.Y.)

    2020  Volume 20, Issue 8, Page(s) 820–830

    Abstract: This review investigates the synthesis and electrochemical performance of the electrode of the electrochemical energy storage (EES) devices obtained from peels and scraps of the citrus fruits. The EES devices include batteries, supercapacitors, and ... ...

    Abstract This review investigates the synthesis and electrochemical performance of the electrode of the electrochemical energy storage (EES) devices obtained from peels and scraps of the citrus fruits. The EES devices include batteries, supercapacitors, and hybrid systems that have considerable value and various applications. The electrode is considered as the most important part of all EES devices. Tremendous efforts have been done to enhance the electrochemical energy storage electrode (EESE). The citrus fruits abundance leads to a decrease in their price and makes possible to use them as ingredients to fabricate EESE. Also, the electrochemical analyses determined that citrus fruits have considerable potential to use as the EESE. Using citrus fruits peels and scraps as biomass substances to prepare EESE leads to the electrodes which have low cost, environmentally friendly and appropriate electrochemical applications.
    MeSH term(s) Biomass ; Carbon/chemistry ; Citrus/chemistry ; Electric Capacitance ; Electric Power Supplies ; Electrochemical Techniques ; Electrodes ; Fruit/chemistry
    Chemical Substances Carbon (7440-44-0)
    Language English
    Publishing date 2020-03-25
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2044646-9
    ISSN 1528-0691 ; 1527-8999
    ISSN (online) 1528-0691
    ISSN 1527-8999
    DOI 10.1002/tcr.202000003
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  10. Article ; Online: Corn-based Electrochemical Energy Storage Devices.

    Parsimehr, Hamidreza / Ehsani, Ali

    Chemical record (New York, N.Y.)

    2020  Volume 20, Issue 10, Page(s) 1163–1180

    Abstract: The attention to renewable materials is amazingly increased in recent years to decrease environmental pollutions. Zea mays (corn) is one of the most produced plants by humans to provide food and energy. Hence, corn wastes as abundant and low-cost biomass ...

    Abstract The attention to renewable materials is amazingly increased in recent years to decrease environmental pollutions. Zea mays (corn) is one of the most produced plants by humans to provide food and energy. Hence, corn wastes as abundant and low-cost biomass are easily found throughout the world. Tremendous efforts have been accomplished in recent years to fabricate electrochemical energy storage devices (EES) from renewable biomass materials because of increasing attention to the environment. All main parts of EES devices include electrodes, binder, electrolyte, and membrane (separator) can be produced via corn waste biochar and corn derivatives. The low-cost corn-based EES devices not only decrease environmental pollution but also have significant electrochemical properties include specific capacitance and electrochemical durability. This review investigates state-of-the-art development in the corn-based EES devices.
    MeSH term(s) Electric Power Supplies ; Electrochemical Techniques ; Zea mays/chemistry
    Language English
    Publishing date 2020-08-07
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2044646-9
    ISSN 1528-0691 ; 1527-8999
    ISSN (online) 1528-0691
    ISSN 1527-8999
    DOI 10.1002/tcr.202000058
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