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  1. Article ; Online: Identification of amentoflavone as a potent SARS-CoV-2 M

    Bhattacharya, Prabuddha / Mandal, Anirban

    Journal of biomolecular structure & dynamics

    2024  , Page(s) 1–19

    Abstract: Small-molecule inhibitors of SARS-CoV-2 ... ...

    Abstract Small-molecule inhibitors of SARS-CoV-2 M
    Language English
    Publishing date 2024-01-23
    Publishing country England
    Document type Journal Article
    ZDB-ID 49157-3
    ISSN 1538-0254 ; 0739-1102
    ISSN (online) 1538-0254
    ISSN 0739-1102
    DOI 10.1080/07391102.2024.2304676
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2093: Show issues Location:
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  2. Article ; Online: Medicinal plant molecules against hepatitis C virus: Current status and future prospect.

    Mandal, Anirban / Hazra, Banasri

    Phytotherapy research : PTR

    2023  Volume 37, Issue 10, Page(s) 4353–4374

    Abstract: Hepatitis C virus (HCV), a global malady, causes acute and chronic hepatitis leading to permanent liver damage, hepatocellular carcinoma, and death. Modern anti-HCV therapies are efficient, but mostly inaccessible for residents of underdeveloped regions. ...

    Abstract Hepatitis C virus (HCV), a global malady, causes acute and chronic hepatitis leading to permanent liver damage, hepatocellular carcinoma, and death. Modern anti-HCV therapies are efficient, but mostly inaccessible for residents of underdeveloped regions. To innovate more effective treatments at affordable cost, medicinal plant-based products need to be explored. The aim of this article is to review plant constituents in the light of putative anti-HCV mechanisms of action, and discuss existing problems, challenges, and future directions for their potential application in therapeutic settings. One hundred sixty literatures were collected by using appropriate search strings via scientific search engines: Google Scholar, PubMed, ScienceDirect, and Scopus. Bibliography was prepared using Mendeley desktop software. We found a substantial number of plants that were reported to inhibit different stages of HCV life cycle. Traditional medicinal plants such as Phyllanthus amarus Schumach. and Thonn., Eclipta alba (L.) Hassk., and Acacia nilotica (L.) Delile exhibited strong anti-HCV activities. Again, several phytochemicals such as epigallocatechin-3-gallate, honokilol, punicalagin, and quercetin have shown broad-spectrum anti-HCV effect. We have presented promising phytochemicals like silymarin, curcumin, glycyrrhizin, and camptothecin for nanoparticle-based hepatocyte-targeted drug delivery. Nevertheless, only a few animal studies have been performed to validate the anti-HCV effect of these plant products. Again, insufficient clinical evaluation of the safety and effectiveness of herbal medications remain a problem. Selected plants products could be developed as novel therapeutics for HCV patients only after scrupulous evaluation of their safety and efficacy in a clinical set-up.
    MeSH term(s) Animals ; Humans ; Plants, Medicinal/chemistry ; Hepacivirus ; Plant Extracts/pharmacology ; Plant Extracts/therapeutic use ; Hepatitis C/drug therapy ; Liver Diseases/drug therapy ; Phytochemicals/pharmacology ; Phytochemicals/therapeutic use
    Chemical Substances Plant Extracts ; Phytochemicals
    Language English
    Publishing date 2023-07-12
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 639136-9
    ISSN 1099-1573 ; 0951-418X
    ISSN (online) 1099-1573
    ISSN 0951-418X
    DOI 10.1002/ptr.7936
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    In stock of ZB MED Cologne/Königswinter

    Zs.B 3092: Show issues Location:
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  3. Article ; Online: C(sp

    Ghosh, Prasanjit / Chhetri, Gautam / Mandal, Anirban / Chen, Yu / Hersh, William H / Das, Sajal

    RSC advances

    2024  Volume 14, Issue 7, Page(s) 4462–4470

    Abstract: Herein, an expeditious metal-free regioselective C-H selenylation of substituted benzo[4,5]imidazo[2,1- ...

    Abstract Herein, an expeditious metal-free regioselective C-H selenylation of substituted benzo[4,5]imidazo[2,1-
    Language English
    Publishing date 2024-02-02
    Publishing country England
    Document type Journal Article
    ISSN 2046-2069
    ISSN (online) 2046-2069
    DOI 10.1039/d4ra00057a
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  4. Article ; Online: Benign polyserositis and acalculous cholecystitis, a rare presentation of acute viral hepatitis A and E co-infection.

    Sahi, Puneet Kaur / Mazhari, Mohammad Yusuf Ali / Mandal, Anirban

    Tropical doctor

    2023  Volume 53, Issue 3, Page(s) 393–395

    MeSH term(s) Humans ; Acalculous Cholecystitis/diagnosis ; Acalculous Cholecystitis/etiology ; Coinfection/diagnosis ; Hepatitis A/complications ; Hepatitis A/diagnosis ; Acute Disease
    Language English
    Publishing date 2023-04-24
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 193169-6
    ISSN 1758-1133 ; 0049-4755
    ISSN (online) 1758-1133
    ISSN 0049-4755
    DOI 10.1177/00494755231170245
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1056: Show issues Location:
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  5. Article: Covalent crosslinking chemistry for controlled modulation of nanometric roughness and surface free energy.

    Sarkar, Debasmita / Dhar, Manideepa / Das, Avijit / Mandal, Sohini / Phukan, Anirban / Manna, Uttam

    Chemical science

    2024  Volume 15, Issue 13, Page(s) 4938–4951

    Abstract: Smooth interfaces embedded with low surface free energy allow effortless sliding of beaded droplets of selected liquids-with homogeneous wettability. Such slippery interfaces display low or moderate contact angles, unlike other extremely liquid repellent ...

    Abstract Smooth interfaces embedded with low surface free energy allow effortless sliding of beaded droplets of selected liquids-with homogeneous wettability. Such slippery interfaces display low or moderate contact angles, unlike other extremely liquid repellent interfaces (
    Language English
    Publishing date 2024-02-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 2559110-1
    ISSN 2041-6539 ; 2041-6520
    ISSN (online) 2041-6539
    ISSN 2041-6520
    DOI 10.1039/d3sc06077b
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  6. Article ; Online: Nonadiabatic transition probabilities for quantum systems in electromagnetic fields: Dephasing and population relaxation due to contact with a bath.

    Jovanovski, Sara D / Mandal, Anirban / Hunt, Katharine L C

    The Journal of chemical physics

    2023  Volume 158, Issue 16

    Abstract: We contrast Dirac's theory of transition probabilities and the theory of nonadiabatic transition probabilities, applied to a perturbed system that is coupled to a bath. In Dirac's analysis, the presence of an excited state |k0⟩ in the time-dependent wave ...

    Abstract We contrast Dirac's theory of transition probabilities and the theory of nonadiabatic transition probabilities, applied to a perturbed system that is coupled to a bath. In Dirac's analysis, the presence of an excited state |k0⟩ in the time-dependent wave function constitutes a transition. In the nonadiabatic theory, a transition occurs when the wave function develops a term that is not adiabatically connected to the initial state. Landau and Lifshitz separated Dirac's excited-state coefficients into a term that follows the adiabatic theorem of Born and Fock and a nonadiabatic term that represents excitation across an energy gap. If the system remains coherent, the two approaches are equivalent. However, differences between the two approaches arise when coupling to a bath causes dephasing, a situation that was not treated by Dirac. For two-level model systems in static electric fields, we add relaxation terms to the Liouville equation for the time derivative of the density matrix. We contrast the results obtained from the two theories. In the analysis based on Dirac's transition probabilities, the steady state of the system is not an equilibrium state; also, the steady-state population ρkk,s increases with increasing strength of the perturbation and its value depends on the dephasing time T2. In the nonadiabatic theory, the system evolves to the thermal equilibrium with the bath. The difference is not simply due to the choice of basis because the difference remains when the results are transformed to a common basis.
    Language English
    Publishing date 2023-04-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3113-6
    ISSN 1089-7690 ; 0021-9606
    ISSN (online) 1089-7690
    ISSN 0021-9606
    DOI 10.1063/5.0138817
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    Z 4' 49/16: Show issues

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  7. Article ; Online: Hybrid Heterocycles: Ag(I)-Catalyzed C-C/C-N/C-O Coupled Cascade Dual Cyclization to Valuable Indolo-4

    Nandi, Rajesh / Ajarul, Sk / Mandal, Prakash K / Manna, Anindya S / Kayet, Anirban / Maiti, Dilip K

    The Journal of organic chemistry

    2024  Volume 89, Issue 4, Page(s) 2556–2570

    Abstract: Herein, we report a highly efficient Ag(I)-catalyzed indolyzation with Friedel-Crafts alkylation through a cascade cyclization strategy for accessing valuable hybrid heterocycles for the first time. This general strategy consists of forming four C-C/C-N/ ... ...

    Abstract Herein, we report a highly efficient Ag(I)-catalyzed indolyzation with Friedel-Crafts alkylation through a cascade cyclization strategy for accessing valuable hybrid heterocycles for the first time. This general strategy consists of forming four C-C/C-N/C-O bonds toward dual annulation reactions of 2-alkynylanilines with methyl benzoate-2-carboxaldehydes and aromatic amines, as well as with salicylaldehydes and malononitrile. Variably substituted new indolo-4
    Language English
    Publishing date 2024-01-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 123490-0
    ISSN 1520-6904 ; 0022-3263
    ISSN (online) 1520-6904
    ISSN 0022-3263
    DOI 10.1021/acs.joc.3c02568
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4473: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  8. Article: Editorial: Plant products for antiviral therapeutics.

    Mandal, Anirban / Hazra, Banasri / Prajapati, Vijay Kumar / Moundipa, Paul F

    Frontiers in pharmacology

    2022  Volume 13, Page(s) 1039183

    Language English
    Publishing date 2022-10-17
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2022.1039183
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  9. Article ; Online: A Phenanthrenequinone-Based Ratiometric Fluorescent Probe for Rapid Detection of Peroxynitrite with Imaging in Osteoblast Precursor Cells.

    Karak, Anirban / Banik, Dipanjan / Ganguly, Rajdeep / Banerjee, Shilpita / Ghosh, Pintu / Maiti, Anwesha / Mandal, Debasish / Mahapatra, Ajit Kumar

    Chemical research in toxicology

    2024  

    Abstract: In the current situation, peroxynitrite ( ... ...

    Abstract In the current situation, peroxynitrite (ONOO
    Language English
    Publishing date 2024-04-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 639353-6
    ISSN 1520-5010 ; 0893-228X
    ISSN (online) 1520-5010
    ISSN 0893-228X
    DOI 10.1021/acs.chemrestox.4c00023
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2320: Show issues Location:
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  10. Article ; Online: Pediatric Liver Abscess: Outcomes of Protocol-based Management and Predictors of Poor Outcome.

    Anand, Mugdha / Sahi, Puneet Kaur / Mandal, Anirban

    The Pediatric infectious disease journal

    2023  Volume 42, Issue 7, Page(s) 549–556

    Abstract: Background: Liver abscess (LA) is an important cause of morbidity in children, especially in tropical countries. There is a paucity of data in pediatric LA with no standard guidelines regarding the best modality of treatment and drainage. With a large ... ...

    Abstract Background: Liver abscess (LA) is an important cause of morbidity in children, especially in tropical countries. There is a paucity of data in pediatric LA with no standard guidelines regarding the best modality of treatment and drainage. With a large influx of patients at our center and protocol-based management; we aimed to study clinic-radiologic profile, risk factors, complications and outcomes of children with liver abscess and assessed possible predictors for poor outcomes.
    Materials and methods: This retrospective observational study was conducted from January 2019 to September 2019 at a tertiary care hospital in India. Records of all children (<12 years of age) with ultrasonographically diagnosed liver abscess were accessed for clinic-radiological and demographic profile, laboratory investigations, treatment, complications and outcomes. Patients were categorized into favorable or unfavorable groups based on predefined criteria and were compared for possible predictors of poor outcomes. Outcomes for the protocol-based management were analyzed.
    Results: There were 120 cases of pediatric liver abscess with a median age of 5 years at presentation. The commonest clinical features were fever (100%) and pain in the abdomen (89.16%). The majority of liver abscesses were solitary (78.4%) and in the right lobe (73.3%). Malnutrition was present in 27.5%, overcrowding for 76.5% of patients and worm infestation in 2.5% of patients. Age-related leukocytosis ( P = 0.004), neutrophilia ( P = 0.013), elevated Aspartate transaminase ( P = 0.008), elevated alanine transaminase ( P = 0.007) and hypoalbuminemia ( P = 0.014) were significantly more in the unfavorable group. Overall, 29.2% of patients underwent conservative management with antibiotics alone, 25.0% underwent percutaneous needle aspiration (PNA), 49.1% underwent ultrasound-guided percutaneous drain (PCD) insertion and open surgical drainage (OSD) was needed in a single patient. The success rate was 100% for conservative management, 76.6% for PNA, 94.7% for PCD and 100% for OSD with an overall mortality of 2.5%.
    Conclusions: Age-related leukocytosis, neutrophilia, elevated aspartate transaminase or alanine transaminase and hypoalbuminemia at presentation are predictors of poor outcomes in pediatric liver abscess. Protocol-based management leads to the appropriate use of PNA and PCD while decreasing mortality and morbidity related to either.
    MeSH term(s) Humans ; Alanine Transaminase ; Anti-Bacterial Agents/therapeutic use ; Drainage ; Hypoalbuminemia/drug therapy ; Leukocytosis ; Liver Abscess/therapy ; Retrospective Studies ; Treatment Outcome ; Ultrasonography, Interventional
    Chemical Substances Alanine Transaminase (EC 2.6.1.2) ; Anti-Bacterial Agents
    Language English
    Publishing date 2023-03-29
    Publishing country United States
    Document type Journal Article ; Observational Study
    ZDB-ID 392481-6
    ISSN 1532-0987 ; 0891-3668
    ISSN (online) 1532-0987
    ISSN 0891-3668
    DOI 10.1097/INF.0000000000003923
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    Zs.A 1852: Show issues Location:
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