LIVIVO - Search results -

Search results

Result 1 - 10 of total 16

Search options

Article ; Online: Suppressed transcript diversity and immune response in COVID-19 ICU patients: a longitudinal study.

Mehta, Priyanka / Chattopadhyay, Partha / Mohite, Ramakant / D'Rozario, Ranit / Bandopadhyay, Purbita / Sarif, Jafar / Ray, Yogiraj / Ganguly, Dipyaman / Pandey, Rajesh

Life science alliance

2023 Volume 7, Issue 1

Abstract: Understanding the dynamic changes in gene expression during Acute Respiratory Distress Syndrome (ARDS) progression in post-acute infection patients is crucial for unraveling the underlying mechanisms. Study investigates the longitudinal changes in gene/ ... ...

Abstract	Understanding the dynamic changes in gene expression during Acute Respiratory Distress Syndrome (ARDS) progression in post-acute infection patients is crucial for unraveling the underlying mechanisms. Study investigates the longitudinal changes in gene/transcript expression patterns in hospital-admitted severe COVID-19 patients with ARDS post-acute SARS-CoV-2 infection. Blood samples were collected at three time points and patients were stratified into severe and mild ARDS, based on their oxygenation saturation (SpO
MeSH term(s)	Humans ; COVID-19/genetics ; Longitudinal Studies ; Bayes Theorem ; SARS-CoV-2 ; Respiratory Distress Syndrome/genetics ; Immunity ; Intensive Care Units ; Disease Progression
Language	English
Publishing date	2023-11-02
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ISSN	2575-1077
ISSN (online)	2575-1077
DOI	10.26508/lsa.202302305
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Piezo1 mechanosensing regulates integrin-dependent chemotactic migration in human T cells.

Liu, Chinky Shiu Chen / Mandal, Tithi / Biswas, Parijat / Hoque, Md Asmaul / Bandopadhyay, Purbita / Sinha, Bishnu Prasad / Sarif, Jafar / D'Rozario, Ranit / Sinha, Deepak Kumar / Sinha, Bidisha / Ganguly, Dipyaman

eLife

2024 Volume 12

Abstract: T cells are crucial for efficient antigen-specific immune responses and thus their migration within the body, to inflamed tissues from circulating blood or to secondary lymphoid organs, plays a very critical role. T cell extravasation in inflamed tissues ...

Abstract	T cells are crucial for efficient antigen-specific immune responses and thus their migration within the body, to inflamed tissues from circulating blood or to secondary lymphoid organs, plays a very critical role. T cell extravasation in inflamed tissues depends on chemotactic cues and interaction between endothelial adhesion molecules and cellular integrins. A migrating T cell is expected to sense diverse external and membrane-intrinsic mechano-physical cues, but molecular mechanisms of such mechanosensing in cell migration are not established. We explored if the professional mechanosensor Piezo1 plays any role during integrin-dependent chemotaxis of human T cells. We found that deficiency of Piezo1 in human T cells interfered with integrin-dependent cellular motility on ICAM-1-coated surface. Piezo1 recruitment at the leading edge of moving T cells is dependent on and follows focal adhesion formation at the leading edge and local increase in membrane tension upon chemokine receptor activation. Piezo1 recruitment and activation, followed by calcium influx and calpain activation, in turn, are crucial for the integrin LFA1 (CD11a/CD18) recruitment at the leading edge of the chemotactic human T cells. Thus, we find that Piezo1 activation in response to local mechanical cues constitutes a membrane-intrinsic component of the 'outside-in' signaling in human T cells, migrating in response to chemokines, that mediates integrin recruitment to the leading edge.
MeSH term(s)	Humans ; Cell Adhesion ; Cell Movement ; Chemokines ; Chemotaxis ; Lymphocyte Function-Associated Antigen-1 ; T-Lymphocytes ; Ion Channels/metabolism
Chemical Substances	Chemokines ; Lymphocyte Function-Associated Antigen-1 ; PIEZO1 protein, human ; Ion Channels
Language	English
Publishing date	2024-02-23
Publishing country	England
Document type	Journal Article
ZDB-ID	2687154-3
ISSN	2050-084X ; 2050-084X
ISSN (online)	2050-084X
ISSN	2050-084X
DOI	10.7554/eLife.91903
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: Association of gut microbial dysbiosis with disease severity, response to therapy and disease outcomes in Indian patients with COVID-19.

Talukdar, Daizee / Bandopadhyay, Purbita / Ray, Yogiraj / Paul, Shekhar Ranjan / Sarif, Jafar / D'Rozario, Ranit / Lahiri, Abhishake / Das, Santanu / Bhowmick, Debaleena / Chatterjee, Shilpak / Das, Bhabatosh / Ganguly, Dipyaman

Gut pathogens

2023 Volume 15, Issue 1, Page(s) 22

Abstract: Background: Severe coronavirus disease 2019 (COVID-19) is associated with systemic hyper-inflammation. An adaptive interaction between gut microbiota and host immune systems is important for intestinal homeostasis and systemic immune regulation. The ... ...

Abstract	Background: Severe coronavirus disease 2019 (COVID-19) is associated with systemic hyper-inflammation. An adaptive interaction between gut microbiota and host immune systems is important for intestinal homeostasis and systemic immune regulation. The association of gut microbial composition and functions with COVID-19 disease severity is sparse, especially in India. We analysed faecal microbial diversity and abundances in a cohort of Indian COVID-19 patients to identify key signatures in the gut microbial ecology in patients with severe COVID-19 disease as well as in response to different therapies. The composition of the gut microbiome was characterized using 16Sr RNA gene sequences of genomic DNA extracted from faecal samples of 52 COVID-19 patients. Metabolic pathways across the groups were predicted using PICRUSt2. All statistical analyses were done using Vegan in the R environment. Plasma cytokine abundance at recruitment was measured in a multiplex assay. Results: The gut microbiome composition of mild and severe patients was found to be significantly different. Immunomodulatory commensals, viz. Lachnospiraceae family members and Bifidobacteria producing butyrate and short-chain fatty acids (SCFAs), were under represented in patients with severe COVID-19, with an increased abundance of opportunistic pathogens like Eggerthella. The higher abundance of Lachnoclostridium in severe disease was reduced in response to convalescent plasma therapy. Specific microbial genera showed distinctive trends in enriched metabolic pathways, strong correlations with blood plasma cytokine levels, and associative link to disease outcomes. Conclusion: Our study indicates that, along with SARS-CoV-2, a dysbiotic gut microbial community may also play an important role in COVID-19 severity through modulation of host immune responses.
Language	English
Publishing date	2023-05-10
Publishing country	England
Document type	Journal Article
ZDB-ID	2478277-4
ISSN	1757-4749
ISSN	1757-4749
DOI	10.1186/s13099-023-00546-z
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Hit-to-lead optimization of 2-aminoquinazolines as anti-microbial agents against Leishmania donovani.

European journal of medicinal chemistry

2024 Volume 269, Page(s) 116256

Abstract: Visceral leishmaniasis is a potentially fatal disease caused by infection by the intracellular protist pathogens Leishmania donovani or Leishmania infantum. Present therapies are ineffective because of high costs, variable efficacy against different ... ...

Abstract	Visceral leishmaniasis is a potentially fatal disease caused by infection by the intracellular protist pathogens Leishmania donovani or Leishmania infantum. Present therapies are ineffective because of high costs, variable efficacy against different species, the requirement for hospitalization, toxicity and drug resistance. Detailed analysis of previously published hit molecules suggested a crucial role of 'guanidine' linkage for their efficacy against L. donovani. Here we report the design of 2-aminoquinazoline heterocycle as a basic pharmacophore-bearing guanidine linkage. The introduction of various groups and functionality at different positions of the quinazoline scaffold results in enhanced antiparasitic potency with modest host cell cytotoxicity using a physiologically relevant THP-1 transformed macrophage infection model. In terms of the ADME profile, the C7 position of quinazoline was identified as a guiding tool for designing better molecules. The good ADME profile of the compounds suggests that they merit further consideration as lead compounds for treating visceral leishmaniasis.
MeSH term(s)	Humans ; Leishmania donovani ; Leishmaniasis, Visceral/drug therapy ; Antiparasitic Agents/pharmacology ; Leishmania infantum ; Quinazolines/pharmacology ; Quinazolines/therapeutic use
Chemical Substances	Antiparasitic Agents ; Quinazolines
Language	English
Publishing date	2024-02-27
Publishing country	France
Document type	Journal Article
ZDB-ID	188597-2
ISSN	1768-3254 ; 0009-4374 ; 0223-5234
ISSN (online)	1768-3254
ISSN	0009-4374 ; 0223-5234
DOI	10.1016/j.ejmech.2024.116256
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.B 784: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Circulating Interleukin-8 Dynamics Parallels Disease Course and Is Linked to Clinical Outcomes in Severe COVID-19.

D'Rozario, Ranit / Raychaudhuri, Deblina / Bandopadhyay, Purbita / Sarif, Jafar / Mehta, Priyanka / Liu, Chinky Shiu Chen / Sinha, Bishnu Prasad / Roy, Jayasree / Bhaduri, Ritwik / Das, Monidipa / Bandyopadhyay, Sanghamitra / Paul, Shekhar Ranjan / Chatterjee, Shilpak / Pandey, Rajesh / Ray, Yogiraj / Ganguly, Dipyaman

Viruses

2023 Volume 15, Issue 2

Abstract: Severe COVID-19 frequently features a systemic deluge of cytokines. Circulating cytokines that can stratify risks are useful for more effective triage and management. Here, we ran a machine-learning algorithm on a dataset of 36 plasma cytokines in a ... ...

Abstract	Severe COVID-19 frequently features a systemic deluge of cytokines. Circulating cytokines that can stratify risks are useful for more effective triage and management. Here, we ran a machine-learning algorithm on a dataset of 36 plasma cytokines in a cohort of severe COVID-19 to identify cytokine/s useful for describing the dynamic clinical state in multiple regression analysis. We performed RNA-sequencing of circulating blood cells collected at different time-points. From a Bayesian Information Criterion analysis, a combination of interleukin-8 (IL-8), Eotaxin, and Interferon-γ (IFNγ) was found to be significantly linked to blood oxygenation over seven days. Individually testing the cytokines in receiver operator characteristics analyses identified IL-8 as a strong stratifier for clinical outcomes. Circulating IL-8 dynamics paralleled disease course. We also revealed key transitions in immune transcriptome in patients stratified for circulating IL-8 at three time-points. The study identifies plasma IL-8 as a key pathogenic cytokine linking systemic hyper-inflammation to the clinical outcomes in COVID-19.
MeSH term(s)	Humans ; Interleukin-8 ; Bayes Theorem ; COVID-19 ; Cytokines ; Disease Progression
Chemical Substances	Interleukin-8 ; Cytokines
Language	English
Publishing date	2023-02-16
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2516098-9
ISSN	1999-4915 ; 1999-4915
ISSN (online)	1999-4915
ISSN	1999-4915
DOI	10.3390/v15020549
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Clinical Trial Subgroup Analyses to Investigate Clinical and Immunological Outcomes of Convalescent Plasma Therapy in Severe COVID-19.

Raychaudhuri, Deblina / Bandopadhyay, Purbita / D'Rozario, Ranit / Sarif, Jafar / Ray, Yogiraj / Paul, Shekhar Ranjan / Singh, Praveen / Chaudhuri, Kausik / Bhaduri, Ritwik / Pandey, Rajesh / Bhattacharya, Prasun / Sengupta, Shantanu / Chatterjee, Shilpak / Ganguly, Dipyaman

Mayo Clinic proceedings. Innovations, quality & outcomes

2022 Volume 6, Issue 6, Page(s) 511–524

Abstract: Objective: To assess the clinical and immunological benefits of passive immunization using convalescent plasma therapy (CPT).: Materials and methods: A series of subclass analyses were performed on the previously published outcome data and ... ...

Abstract	Objective: To assess the clinical and immunological benefits of passive immunization using convalescent plasma therapy (CPT). Materials and methods: A series of subclass analyses were performed on the previously published outcome data and accompanying clinical metadata from a completed randomized controlled trial (RCT) (Clinical Trial Registry of India, number CTRI/2020/05/025209). The subclass analyses were performed on the outcome data and accompanying clinical metadata from a completed RCT (patient recruitment between May 15, 2020 and October 31, 2020). Data on the plasma abundance of a large panel of cytokines from the same cohort of patients were also used to characterize the heterogeneity of the putative anti-inflammatory function of convalescent plasma (CP) in addition to passively providing neutralizing antibodies. Results: Although the primary clinical outcomes were not significantly different in the RCT across all age groups, significant immediate mitigation of hypoxia, reduction in hospital stay, and significant survival benefit were registered in younger (<67 years in our cohort) patients with severe coronavirus disease 2019 and acute respiratory distress syndrome on receiving CPT. In addition to neutralizing the antibody content of CP, its anti-inflammatory proteome, by attenuation of the systemic cytokine deluge, significantly contributed to the clinical benefits of CPT. Conclusion: Subgroup analyses revealed that clinical benefits of CPT in severe coronavirus disease 2019 are linked to the anti-inflammatory protein content of CP apart from the anti-severe acute respiratory syndrome coronavirus 2 neutralizing antibody content.
Language	English
Publishing date	2022-09-14
Publishing country	Netherlands
Document type	Journal Article
ISSN	2542-4548
ISSN (online)	2542-4548
DOI	10.1016/j.mayocpiqo.2022.09.001
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Role of Ca

Raychaudhuri, Deblina / Duttagupta, Pritam / Liu, Chinky Shiu Chen / Sarif, Jafar / Ghosh, Amrit Raj / Rahaman, Oindrila / Ganguly, Dipyaman

Cytokine

2019 Volume 125, Page(s) 154822

Abstract: Plasmacytoid dendritic cells (pDCs) are major producers of type I interferons in response to activation of endosomal toll-like receptors (TLRs), e.g. TLR9. While a number of cell biological and intracellular signaling events associated with TLR9 ... ...

Abstract	Plasmacytoid dendritic cells (pDCs) are major producers of type I interferons in response to activation of endosomal toll-like receptors (TLRs), e.g. TLR9. While a number of cell biological and intracellular signaling events associated with TLR9 activation in pDCs have been studied, role of free calcium (Ca
MeSH term(s)	Antimicrobial Cationic Peptides/metabolism ; Calcineurin/metabolism ; Calcium/metabolism ; Calcium/pharmacology ; Calcium-Calmodulin-Dependent Protein Kinase Type 2/metabolism ; Cells, Cultured ; DNA/immunology ; Dendritic Cells/drug effects ; Dendritic Cells/immunology ; Dendritic Cells/metabolism ; Flow Cytometry ; Humans ; Interferon-alpha/metabolism ; Oligodeoxyribonucleotides/pharmacology ; Signal Transduction/immunology ; Toll-Like Receptor 9/metabolism
Chemical Substances	Antimicrobial Cationic Peptides ; CPG-oligonucleotide ; Interferon-alpha ; Oligodeoxyribonucleotides ; TLR9 protein, human ; Toll-Like Receptor 9 ; ropocamptide (3DD771JO2H) ; DNA (9007-49-2) ; Calcium-Calmodulin-Dependent Protein Kinase Type 2 (EC 2.7.11.17) ; Calcineurin (EC 3.1.3.16) ; Calcium (SY7Q814VUP)
Language	English
Publishing date	2019-08-27
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1018055-2
ISSN	1096-0023 ; 1043-4666
ISSN (online)	1096-0023
ISSN	1043-4666
DOI	10.1016/j.cyto.2019.154822
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 2840: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Lactate Induces Pro-tumor Reprogramming in Intratumoral Plasmacytoid Dendritic Cells.

Raychaudhuri, Deblina / Bhattacharya, Roopkatha / Sinha, Bishnu Prasad / Liu, Chinky Shiu Chen / Ghosh, Amrit Raj / Rahaman, Oindrila / Bandopadhyay, Purbita / Sarif, Jafar / D'Rozario, Ranit / Paul, Santu / Das, Anirban / Sarkar, Diptendra K / Chattopadhyay, Samit / Ganguly, Dipyaman

Frontiers in immunology

2019 Volume 10, Page(s) 1878

Abstract: Plasmacytoid dendritic cells are the most efficient producers of type I interferons, viz. IFNα, in the body and thus have the ability to influence anti-tumor immune responses. But repression of effective intra-tumoral pDC activation is a key immuno- ... ...

Abstract	Plasmacytoid dendritic cells are the most efficient producers of type I interferons, viz. IFNα, in the body and thus have the ability to influence anti-tumor immune responses. But repression of effective intra-tumoral pDC activation is a key immuno-evasion strategy exhibited in tumors-tumor-recruited pDCs are rendered "tolerogenic," characterized by deficiency in IFNα induction and ability to expand regulatory T cells
MeSH term(s)	Animals ; Breast Neoplasms/immunology ; Breast Neoplasms/metabolism ; Cellular Reprogramming/immunology ; Dendritic Cells/immunology ; Dendritic Cells/metabolism ; Female ; Humans ; Lactic Acid/immunology ; Lactic Acid/metabolism ; Mice ; T-Lymphocytes, Regulatory/immunology ; Tumor Escape/physiology ; Tumor Microenvironment/immunology
Chemical Substances	Lactic Acid (33X04XA5AT)
Language	English
Publishing date	2019-08-07
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2606827-8
ISSN	1664-3224 ; 1664-3224
ISSN (online)	1664-3224
ISSN	1664-3224
DOI	10.3389/fimmu.2019.01878
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Clinical Trial Subgroup Analyses to Investigate Clinical and Immunological Outcomes of Convalescent Plasma Therapy in Severe COVID-19

Deblina Raychaudhuri, PhD / Purbita Bandopadhyay, MS / Ranit D’Rozario, MS / Jafar Sarif, MS / Yogiraj Ray, MBBS, MD, DM / Shekhar Ranjan Paul, MBBS, DTCD / Praveen Singh, MS / Kausik Chaudhuri, MBBS, MD / Ritwik Bhaduri, MS / Rajesh Pandey, PhD / Prasun Bhattacharya, MBBS, MD / Shantanu Sengupta, PhD / Shilpak Chatterjee, PhD / Dipyaman Ganguly, MBBS, PhD

Mayo Clinic Proceedings: Innovations, Quality & Outcomes, Vol 6, Iss 6, Pp 511-

2022 Volume 524

Abstract: Objective: To assess the clinical and immunological benefits of passive immunization using convalescent plasma therapy (CPT). Materials and Methods: A series of subclass analyses were performed on the previously published outcome data and accompanying ... ...

Abstract	Objective: To assess the clinical and immunological benefits of passive immunization using convalescent plasma therapy (CPT). Materials and Methods: A series of subclass analyses were performed on the previously published outcome data and accompanying clinical metadata from a completed randomized controlled trial (RCT) (Clinical Trial Registry of India, number CTRI/2020/05/025209). The subclass analyses were performed on the outcome data and accompanying clinical metadata from a completed RCT (patient recruitment between May 15, 2020 and October 31, 2020). Data on the plasma abundance of a large panel of cytokines from the same cohort of patients were also used to characterize the heterogeneity of the putative anti-inflammatory function of convalescent plasma (CP) in addition to passively providing neutralizing antibodies. Results: Although the primary clinical outcomes were not significantly different in the RCT across all age groups, significant immediate mitigation of hypoxia, reduction in hospital stay, and significant survival benefit were registered in younger (<67 years in our cohort) patients with severe coronavirus disease 2019 and acute respiratory distress syndrome on receiving CPT. In addition to neutralizing the antibody content of CP, its anti-inflammatory proteome, by attenuation of the systemic cytokine deluge, significantly contributed to the clinical benefits of CPT. Conclusion: Subgroup analyses revealed that clinical benefits of CPT in severe coronavirus disease 2019 are linked to the anti-inflammatory protein content of CP apart from the anti–severe acute respiratory syndrome coronavirus 2 neutralizing antibody content.
Keywords	Medicine (General) ; R5-920
Subject code	610
Language	English
Publishing date	2022-12-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Nature and Dimensions of Systemic Hyperinflammation and its Attenuation by Convalescent Plasma in Severe COVID-19.

Bandopadhyay, Purbita / D'Rozario, Ranit / Lahiri, Abhishake / Sarif, Jafar / Ray, Yogiraj / Paul, Shekhar Ranjan / Roy, Rammohan / Maiti, Rajshekhar / Chaudhuri, Kausik / Bagchi, Saugata / Maiti, Ayan / Perwez, Mohammed Masoom / Sarkar, Biswanath Sharma / Roy, Devlina / Chakraborty, Rahul / Vasudevan, Janani Srinivasa / Sharma, Sachin / Biswas, Durba / Maiti, Chikam /

Saha, Bibhuti / Bhattacharya, Prasun / Pandey, Rajesh / Chatterjee, Shilpak / Paul, Sandip / Ganguly, Dipyaman

The Journal of infectious diseases

2021 Volume 224, Issue 4, Page(s) 565–574

Abstract: Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), causing coronavirus disease 2019 (COVID-19), has led to significant morbidity and mortality. While most suffer from mild symptoms, some patients progress to severe disease with ... ...

Abstract	Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), causing coronavirus disease 2019 (COVID-19), has led to significant morbidity and mortality. While most suffer from mild symptoms, some patients progress to severe disease with acute respiratory distress syndrome (ARDS) and associated systemic hyperinflammation. Methods: First, to characterize key cytokines and their dynamics in this hyperinflammatory condition, we assessed abundance and correlative expression of a panel of 48 cytokines in patients progressing to ARDS as compared to patients with mild disease. Then, in an ongoing randomized controlled trial of convalescent plasma therapy (CPT), we analyzed rapid effects of CPT on the systemic cytokine dynamics as a correlate for the level of hypoxia experienced by the patients. Results: We identified an anti-inflammatory role of CPT independent of its neutralizing antibody content. Conclusions: Neutralizing antibodies, as well as reductions in circulating interleukin-6 and interferon-γ-inducible protein 10, contributed to marked rapid reductions in hypoxia in response to CPT. Clinical trial registry of india: CTRI/2020/05/025209. http://www.ctri.nic.in/.
MeSH term(s)	Adult ; Anti-Inflammatory Agents/therapeutic use ; Antibodies, Neutralizing/immunology ; COVID-19/epidemiology ; COVID-19/immunology ; COVID-19/therapy ; COVID-19/virology ; Cytokines/blood ; Cytokines/immunology ; Female ; Humans ; Immunization, Passive/methods ; India/epidemiology ; Male ; Middle Aged ; Plasma ; RNA, Viral/isolation & purification ; Respiratory Distress Syndrome/drug therapy ; Respiratory Distress Syndrome/immunology ; SARS-CoV-2/immunology ; SARS-CoV-2/isolation & purification ; Viral Load ; COVID-19 Drug Treatment ; COVID-19 Serotherapy
Chemical Substances	Anti-Inflammatory Agents ; Antibodies, Neutralizing ; Cytokines ; RNA, Viral
Language	English
Publishing date	2021-08-13
Publishing country	United States
Document type	Journal Article ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
ZDB-ID	3019-3
ISSN	1537-6613 ; 0022-1899
ISSN (online)	1537-6613
ISSN	0022-1899
DOI	10.1093/infdis/jiab010
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Uh II Zs.50: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG)
Zs.MO 445: Show issues

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

To top

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito