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Book ; Online ; E-Book: Nanotechnology applications for cancer chemotherapy

Jain, Sanyog / Raza, Kaisar / Agrawal, Ashish Kumar / Vaidya, Ankur

(Micro and nano technologies)

2020

Author's details	Sanyog Jain, Kaisar Raza, Ashish Kumar Agrawal, Ankur Vaidya
Series title	Micro and nano technologies
Keywords	Cancer/Chemotherapy ; Nanomedicine ; Biomedical materials
Subject code	616.994061
Language	English
Size	1 Online-Ressource (xx, 683 Seiten)
Publisher	Elsevier
Publishing place	Amsterdam
Publishing country	Netherlands
Document type	Book ; Online ; E-Book
Remark	Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
HBZ-ID	HT020670177
ISBN	978-0-12-817847-8 ; 9780128178461 ; 0-12-817847-7 ; 0128178469
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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Article: Alterations of Gastrointestinal Microbe Composition in Various Human Diseases and Its Significance in the Early Diagnosis of Diseases.

Agrawal, Aman / Anjankar, Ashish

Cureus

2024 Volume 16, Issue 1, Page(s) e52435

Abstract: A 100 trillion bacteria, viruses, fungi, and archaea make up the human gut microbe. It has co-evolved with its human host and carries out essential tasks that improve general health. The relationship between gastrointestinal microbes and human health has ...

Abstract	A 100 trillion bacteria, viruses, fungi, and archaea make up the human gut microbe. It has co-evolved with its human host and carries out essential tasks that improve general health. The relationship between gastrointestinal microbes and human health has been a growing field of interest and research in recent times. The gastrointestinal microbes are connected by complex networks and connections, and the host has given birth to the gut-microbe-brain axis, which shows the crucial effect that this circumstance could have on the health and diseases of the brain and spinal cord (or the central nervous system [CNS]). The microbe and the CNS interact bi-directionally via autonomic, neuroendocrine, gastrointestinal, and immune system pathways. The gut microbe has been connected to a range of gastrointestinal and extra-gastrointestinal diseases. The recent investigation supports the suspicion that the gut-microbe-brain axis could play a role in neuropsychiatric disorders including depression, dementia, post-traumatic stress disorder, anxiousness, bipolar disorder, schizophrenia, and obsessive-compulsive disorder, alongside chronic host illnesses such as obesity, diabetes, and inflammation. Studies point to gut microorganisms as possible biomarkers for a wide range of mental health issues. Changes in the gut microbe may be a crucial factor in the onset and advancement of non-alcoholic fatty liver damage. Gut microbes have been seen to influence microglia's response to the CNS's regional signals and thus to pain and inflammation. Data suggest that altering the gut microbe in those with chronic pain may be a successful method for reducing pain. Numerous investigations have documented alterations in the gut microbes made in Alzheimer patients and schizophrenic patients. The risk of breast cancer can be reduced by restoring gut microbe homeostasis and reducing systemic estrogen levels.
Language	English
Publishing date	2024-01-17
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.52435
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Article: Brodie Bite: A Clinical Challenge.

Agrawal, Ashish

International journal of clinical pediatric dentistry

2020 Volume 13, Issue 3, Page(s) 288–294

Abstract: ... modifications in mechanotherapy.: How to cite this article: Agrawal A. Brodie Bite: A Clinical Challenge. Int ...

Abstract	Treatment of the posterior crossbite (Brodie bite) case is always challenging for orthodontics. The case requires meticulous treatment planning and is often difficult and time-consuming to treat Brodie bite. This kind of malocclusion develops partially because of lingual tipping of the lower segments, and partially because of a lower jaw too small, relative to the maxilla. A young male 12 years of age came to the dental department with chief complaints of unable to chew food and with lower jaw teeth contained within the upper jaw. Clinical examination revealed class II div I malocclusion, increased overjet and lingually locked upper left lateral incisor with just one occlusal contact at the left first molar region (mandibular teeth contained within the maxillary dentition). Though there are various treatment options available such as extractions, expansion, dental arch compensation, or orthognathic surgery for treating Brodie bite, the best treatment option should be chosen, which requires proper diagnosis. This article discusses one such case that was diagnosed and planned as three-phase treatment with two modifications in mechanotherapy. How to cite this article: Agrawal A. Brodie Bite: A Clinical Challenge. Int J Clin Pediatr Dent 2020;13(3):288-294.
Language	English
Publishing date	2020-07-08
Publishing country	India
Document type	Case Reports
ISSN	0974-7052
ISSN	0974-7052
DOI	10.5005/jp-journals-10005-1748
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Article: Prevalence of Stress and Insomnia among Health Care Workers in India during COVID-19 Pandemic: A Systematic Review and Meta-analysis.

Khobragade, Ashish W / Agrawal, Nitin

Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine

2023 Volume 48, Issue 4, Page(s) 525–532

Abstract: Background: Health care workers (HCWs) are prone to stress and insomnia because of pandemic situations. Assessment of the actual burden of this stress and insomnia is essential to form preventive strategies. The study's objective was to find out the ... ...

Abstract	Background: Health care workers (HCWs) are prone to stress and insomnia because of pandemic situations. Assessment of the actual burden of this stress and insomnia is essential to form preventive strategies. The study's objective was to find out the pooled prevalence of stress and insomnia among HCWs in India during the coronavirus disease (COVID-19) pandemic. Material and methods: We conducted a systematic review and meta-analysis to determine the prevalence of stress and insomnia among HCWs during the COVID-19 pandemic in India. Cross-sectional studies conducted in India regarding stress and insomnia among HCWs were searched from PubMed, Scopus, Embase, and Google Scholar. These studies were published after the declaration of the COVID-19 pandemic till August 31, 2021. Articles were searched independently by both authors. Data were extracted in an Excel sheet and analyzed using the 'Meta' package of the 'R' software version 4.1.0. Result: A total of 23 and 16 studies were included in the final pooled analysis of stress and insomnia, respectively, following preferred reporting items for systematic review and meta-analysis guidelines. A random-effects model was used to determine the pooled prevalence of stress and insomnia. This study is registered in Prospero. The registration number is CRD42021253917. The total numbers of HCWs from India included were 8125 and 4974, respectively, for finding out the pooled prevalence of stress and insomnia. The pooled prevalence of stress and insomnia among HCWs is 43% [95% confidence interval (CI) 30-56%] and 35% (95% CI 28-44%), respectively. Two out of five and one in three Indian HCWs have stress and insomnia, respectively, during the COVID-19 pandemic. Conclusion: Human resource development should be prioritized to decrease the workload among HCWs. The findings from this study will be useful in preparing policy guidelines on mental health screening of HCWs during the pandemic.
Language	English
Publishing date	2023-07-14
Publishing country	India
Document type	Journal Article ; Review
ZDB-ID	2085330-0
ISSN	1998-3581 ; 0970-0218
ISSN (online)	1998-3581
ISSN	0970-0218
DOI	10.4103/ijcm.ijcm_482_22
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Article: Covid-19-Associated Mucormycosis: Histopathology of the Deadly Fungal Infection.

Anand, Nidhi / Srivastava, Pallavi / Agrawal, Ashish Chandra / Gupta, Nikhil / Das, Anupam / Husain, Nuzhat

International archives of otorhinolaryngology

2024 Volume 28, Issue 2, Page(s) e240–e246

Abstract: ... ...

Abstract	Introduction
Language	English
Publishing date	2024-01-24
Publishing country	Brazil
Document type	Journal Article
ZDB-ID	2578584-9
ISSN	1809-4864 ; 1809-9777
ISSN (online)	1809-4864
ISSN	1809-9777
DOI	10.1055/s-0043-1776729
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Article: Dental Caries in Permanent First Molar and Its Association with Carious Primary Second Molar among 6-11-Year-Old School Children in Sunsari, Nepal.

Agrawal, Santosh Kumari / Bhagat, Tarakant / Shrestha, Ashish

International journal of dentistry

2023 Volume 2023, Page(s) 9192167

Abstract: The permanent first molar (PFM) plays an essential role in maintaining the dental and overall health of an individual. It is the most susceptible tooth to dental caries due to its early eruption and location near the primary second molar in the oral ... ...

Abstract	The permanent first molar (PFM) plays an essential role in maintaining the dental and overall health of an individual. It is the most susceptible tooth to dental caries due to its early eruption and location near the primary second molar in the oral cavity. We assessed the clinical status of the PFM and its association with carious primary second molars among 6-11-year-old children in Sunsari, Nepal, from January 2019 to December 2021. We recorded DMFT/DMFS and dft/dfs indices of the first permanent molar and secondary primary molar. Chi-square, logistic regression, and Spearman rank correlation (
Language	English
Publishing date	2023-03-21
Publishing country	Egypt
Document type	Journal Article
ZDB-ID	2546524-7
ISSN	1687-8736 ; 1687-8728
ISSN (online)	1687-8736
ISSN	1687-8728
DOI	10.1155/2023/9192167
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Article ; Online: Investigations on melamine-based uric acid kidney stone formation and its prevention by inhibitors.

Pradhane, Ashish P / Methekar, Ravi N / Agrawal, Shailesh G

Urolithiasis

2023 Volume 51, Issue 1, Page(s) 68

Abstract: Melamine (Mel) as a milk powder adulterant came to light in September 2008, when a kidney stone disease (KSD) outbreak struck China. The mechanism of the formation of Mel-associated uric acid (UA) stones is relatively unknown. Therefore, in the present ... ...

Abstract	Melamine (Mel) as a milk powder adulterant came to light in September 2008, when a kidney stone disease (KSD) outbreak struck China. The mechanism of the formation of Mel-associated uric acid (UA) stones is relatively unknown. Therefore, in the present study, Mel's influence was explored at comparatively higher and lower concentrations in artificial urine. The parameter optimization performed when the Mel concentration in artificial urine was low, which revealed that higher pH values and lower UA concentration considerably delayed the induction of UA crystallization. When Mel concentration was increased relative to UA concentration, the induction time of UA crystallization decreased dramatically. At the highest concentration of Mel investigated (at UA-Mel molar ratio 1:1), PXRD analysis and SEM revealed a change in crystalline structure of the samples. Based on FTIR analysis, it was determined that UA-Mel interactions are essentially physical, because no new characteristic bands developed. Two inhibitors, namely tri-potassium citrate (TPC) and 3, 7-dimethylxanthine (DMX), were investigated for their inhibitory action on UA crystallization in the presence of Mel. DMX was observed to be more promising than TPC in delaying the induction of crystallisation and hence inhibiting crystal formation.
MeSH term(s)	Humans ; Uric Acid/chemistry ; Kidney Calculi/etiology ; Triazines/chemistry ; China
Chemical Substances	Uric Acid (268B43MJ25) ; melamine (N3GP2YSD88) ; Triazines
Language	English
Publishing date	2023-04-11
Publishing country	Germany
Document type	Journal Article
ZDB-ID	2703553-0
ISSN	2194-7236 ; 2194-7228
ISSN (online)	2194-7236
ISSN	2194-7228
DOI	10.1007/s00240-023-01437-3
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Article: Contribution of masticatory muscle pattern to craniofacial morphology in normal adults: A cross-sectional MRI study.

Agrawal, Ashish / Kumar, Vadivel / Pillai, Ajit R

National journal of maxillofacial surgery

2023 Volume 14, Issue 2, Page(s) 213–220

Abstract: Purpose: The study aimed to determine the muscle pattern of medial pterygoid, lateral pterygoid, and masseter (length, cross-section, and angulation) in adult non-orthodontic patients and its effect on craniofacial structures.: Methods: The study was ...

Abstract	Purpose: The study aimed to determine the muscle pattern of medial pterygoid, lateral pterygoid, and masseter (length, cross-section, and angulation) in adult non-orthodontic patients and its effect on craniofacial structures. Methods: The study was conducted from January 14, 2019 to January 14, 2020. Ethical clearance of this study was obtained from the ethical committee Ethical Clearance was obtained from Faculty of Dental Sciences, IMS, BHU, Institutional Ethical Committee with Ref no. Dean/2019/EC/1824 dated 23.04.2019 of the university. The sample size was estimated using the G-power statistical program. Power analysis indicated a minimum sample size of 27. Inclusion and exclusion criteria were set. Consent was taken from participants. Seventy-seven subjects who were willing to participate and have given written consent were enrolled for the study. Participants were sent for lateral cephalometry (Dolphin Cephalometric software) Dolphin Imaging and management solution, for 6 angular and 11 linear measurements. Nineteen subjects did not turn up for the scan. Twenty-eight participants underwent MRI (magnetic resonance imaging) to evaluate muscle patterns (masseter, medial, and lateral pterygoid). The intra-class correlation coefficient (ICC), Kolmogorov-Smirnov (KS) test, descriptive statistics, and multiple regression analysis were computed. The P value was set as ≤0.001(highly statistically significant) and ≤0.05 (significant relation). Results: There was a highly statistically significant (p ≤ 0.001) association between masseter length to upper facial height (N-Ans) and ramal length (Cd-Go). Length of medial pterygoid was significantly related (p ≤ 0.05) with SNB and length of body of mandible (Pog-Go). The cross-section of this muscle showed significant relation with upper facial height (N-Ans) and ramal length (Cd-Go). The correlation of the length of lateral pterygoid with upper facial height (N-Ans) and maxillary length (A-Ptm) was highly significant. Conclusion: The muscle pattern has a significant correlation with maxillofacial morphology. The masseter muscle is the longest and thickest (cross-section) and is angulated vertically than the other two muscles (medial pterygoid and lateral pterygoid). Of the three muscles, the medial pterygoid influences more common craniofacial parameters suggestive of its symbiotic activity. Lateral pterygoid affects the maxillary length and facial height.
Language	English
Publishing date	2023-07-13
Publishing country	India
Document type	Journal Article
ZDB-ID	2653583-X
ISSN	2229-3418 ; 0975-5950
ISSN (online)	2229-3418
ISSN	0975-5950
DOI	10.4103/njms.njms_473_21
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Article ; Online: Subconjunctival dexamethasone-assisted conjunctival autograft harvesting versus normal saline during pterygium surgery - A randomized clinical trial.

Meena, Ashok / Agrawal, Ashish / Parmar, Gautam / Gurnani, Bharat

Indian journal of ophthalmology

2023 Volume 72, Issue 2, Page(s) 217–222

Abstract: Purpose: To evaluate the effect of subconjunctival dexamethasone compared to normal saline on conjunctival autograft harvesting in patients undergoing pterygium surgery.: Methods: Fifty-two eyes of 52 patients who underwent pterygium excision ... ...

Abstract	Purpose: To evaluate the effect of subconjunctival dexamethasone compared to normal saline on conjunctival autograft harvesting in patients undergoing pterygium surgery. Methods: Fifty-two eyes of 52 patients who underwent pterygium excision combined with autologous conjunctival graft (CAG) using releasable suture were included in this prospective interventional study. The patients were randomized into two groups of 26 patients each. Group A consisted of patients in whom CAG was harvested using subconjunctival 0.5 ml of 0.4% dexamethasone sodium phosphate and in group B patients, normal saline was used. The patients were assessed for postoperative pain, foreign body sensation, and watering as the subjective signs of inflammation and conjunctival inflammation and lid edema as the objective signs of inflammation at 12 and 24 h postsurgery. Results: The mean age of group A and B patients was 47.69 + 13.09 and 46.00 + 10.76 years, respectively. The male:female ratio was 1.6:1 in group A and 1.1:1 in group B. The mean surgical time in group A was 243.96 ± 52.13 s and in group B was 258.08 ± 43.99 s. Postoperative pain, foreign body sensation, and watering were significantly lower in group A patients than in group B patients at both 12 and 24 h postoperatively (group A: 4.65 ± 1.33, 4.88 ± 1.73, and 3.85 ± 1.43, respectively, at 12 h; 1.89 ± 1.03, 1.69 ± 1.09, and 1.69 ± 0.97, respectively, at 24 h and group B: 6.42 ± 0.95, 6.65 ± 0.98, and 6.27 ± 1.40, respectively, at 12 h; 3.27 ± 1.43, 3.12 ± 1.25, 2.58 ± 1.14, respectively, at 24 h) ( P < 0.001). Conjunctival inflammation was significantly lower in group A at 12 h ( P < 0.05) and 24 h ( P < 0.05) after surgery compared to group B. Lid edema failed to show any significant ( P = 0.17) difference with respect to severity in both the groups at 12 and 24 h ( P = 0.699). Conclusion: Subconjunctival dexamethasone decreased patient discomfort following pterygium surgery. The dexamethasone group had reduced conjunctival inflammatory signs without any notable complications.
MeSH term(s)	Humans ; Male ; Female ; Adult ; Middle Aged ; Pterygium/complications ; Saline Solution ; Autografts ; Prospective Studies ; Treatment Outcome ; Conjunctiva/surgery ; Transplantation, Autologous/adverse effects ; Conjunctivitis/etiology ; Pain, Postoperative ; Recurrence ; Inflammation ; Dexamethasone ; Edema/diagnosis ; Edema/etiology ; Edema/prevention & control ; Foreign Bodies ; Follow-Up Studies
Chemical Substances	Saline Solution ; Dexamethasone (7S5I7G3JQL)
Language	English
Publishing date	2023-12-15
Publishing country	India
Document type	Randomized Controlled Trial ; Journal Article
ZDB-ID	187392-1
ISSN	1998-3689 ; 0301-4738
ISSN (online)	1998-3689
ISSN	0301-4738
DOI	10.4103/IJO.IJO_969_23
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Zs.B 329: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG)
Zs.MO 598: Show issues

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Article: The Oral Health Condition of Patients on Hemodialysis at a Tertiary Healthcare Facility in Eastern Nepal.

Joshi, Naresh Prasad / Shrestha, Ashish / Bhagat, Tarakant / Agrawal, Santosh Kumari / Chhetri, Roshan

International journal of dentistry

2024 Volume 2024, Page(s) 3776702

Abstract: Objectives: This study was done to compare the oral health of chronic kidney disease (CKD) patients on hemodialysis to healthy individuals and to assess the effect of the duration of dialysis on oral health.: Materials and methods: A comparative ... ...

Abstract	Objectives: This study was done to compare the oral health of chronic kidney disease (CKD) patients on hemodialysis to healthy individuals and to assess the effect of the duration of dialysis on oral health. Materials and methods: A comparative cross-sectional study was conducted among purposively selected 54 cases undergoing dialysis and 54 apparently healthy controls. Caries experience and periodontal status were recorded under similar examination conditions and compared between cases and controls. The correlation between oral health and the duration of dialysis was assessed. A Results: The mean age of the participants was 47.09 ± 12.23 years. Median caries experience among cases and controls was two (0-26) and three (0-15), respectively ( Conclusion: Significant differences exist between the periodontal health of patients undergoing dialysis compared to healthy controls. Longitudinal studies are required to check the causal effect of CKD on periodontitis.
Language	English
Publishing date	2024-02-12
Publishing country	Egypt
Document type	Journal Article
ZDB-ID	2546524-7
ISSN	1687-8736 ; 1687-8728
ISSN (online)	1687-8736
ISSN	1687-8728
DOI	10.1155/2024/3776702
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