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  1. Article ; Online: More journal articles and fewer books: Publication practices in the social sciences in the 2010's.

    Savage, William E / Olejniczak, Anthony J

    PloS one

    2022  Volume 17, Issue 2, Page(s) e0263410

    Abstract: The number of scholarly journal articles published each year is growing, but little is known about the relationship between journal article growth and other forms of scholarly dissemination (e.g., books and monographs). Journal articles are the de facto ... ...

    Abstract The number of scholarly journal articles published each year is growing, but little is known about the relationship between journal article growth and other forms of scholarly dissemination (e.g., books and monographs). Journal articles are the de facto currency of evaluation and prestige in STEM fields, but social scientists routinely publish books as well as articles, representing a unique opportunity to study increased article publications in disciplines with other dissemination options. We studied the publishing activity of social science faculty members in 12 disciplines at 290 Ph.D. granting institutions in the United States between 2011 and 2019, asking: 1) have publication practices changed such that more or fewer books and articles are written now than in the recent past?; 2) has the percentage of scholars actively participating in a particular publishing type changed over time?; and 3) do different age cohorts evince different publication strategies? In all disciplines, journal articles per person increased between 3% and 64% between 2011 and 2019, while books per person decreased by at least 31% and as much as 54%. All age cohorts show increased article authorship over the study period, and early career scholars author more articles per person than the other cohorts in eight disciplines. The article-dominated literatures of the social sciences are becoming increasingly similar to those of STEM disciplines.
    MeSH term(s) Authorship ; Databases, Factual ; Education ; Faculty ; Financing, Organized ; Humans ; Publications ; Publishing/trends ; Social Sciences/methods ; Social Sciences/trends ; United States ; Writing
    Language English
    Publishing date 2022-02-03
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0263410
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: It's time to step up to the plate and BAT.

    Savage, William J

    Transfusion

    2017  Volume 57, Issue 9, Page(s) 2061–2062

    Language English
    Publishing date 2017-09
    Publishing country United States
    Document type Editorial
    ZDB-ID 208417-x
    ISSN 1537-2995 ; 0041-1132
    ISSN (online) 1537-2995
    ISSN 0041-1132
    DOI 10.1111/trf.14253
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 284: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: The Rhythms of Scholarly Publication: Suggestions to Enhance Bibliometric Comparisons Across Disciplines.

    Olejniczak, Anthony J / Savage, William E / Wheeler, Richard

    Frontiers in research metrics and analytics

    2022  Volume 7, Page(s) 812312

    Language English
    Publishing date 2022-01-25
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2504-0537
    ISSN (online) 2504-0537
    DOI 10.3389/frma.2022.812312
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Transfusion Reactions.

    Savage, William J

    Hematology/oncology clinics of North America

    2016  Volume 30, Issue 3, Page(s) 619–634

    Abstract: Transfusion reactions are common occurrences, and clinicians who order or transfuse blood components need to be able to recognize adverse sequelae of transfusion. The differential diagnosis of any untoward clinical event should always consider adverse ... ...

    Abstract Transfusion reactions are common occurrences, and clinicians who order or transfuse blood components need to be able to recognize adverse sequelae of transfusion. The differential diagnosis of any untoward clinical event should always consider adverse sequelae of transfusion, even when transfusion occurred weeks earlier. There is no pathognomonic sign or symptom that differentiates a transfusion reaction from other potential medical problems, so vigilance is required during and after transfusion when a patient presents with a change in clinical status. This review covers the presentation, mechanisms, and management of transfusion reactions that are commonly encountered, and those that can be life-threatening.
    MeSH term(s) Blood Component Transfusion/adverse effects ; Blood Component Transfusion/methods ; Humans
    Language English
    Publishing date 2016-06
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 93115-9
    ISSN 1558-1977 ; 0889-8588
    ISSN (online) 1558-1977
    ISSN 0889-8588
    DOI 10.1016/j.hoc.2016.01.012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Se 1077: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: The Rhythms of Scholarly Publication

    Anthony J. Olejniczak / William E. Savage / Richard Wheeler

    Frontiers in Research Metrics and Analytics, Vol

    Suggestions to Enhance Bibliometric Comparisons Across Disciplines

    2022  Volume 7

    Keywords bibliometrics ; higher education research ; academic publishing ; academic disciplines ; research evaluation ; Bibliography. Library science. Information resources ; Z
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: More journal articles and fewer books

    William E Savage / Anthony J Olejniczak

    PLoS ONE, Vol 17, Iss 2, p e

    Publication practices in the social sciences in the 2010's.

    2022  Volume 0263410

    Abstract: The number of scholarly journal articles published each year is growing, but little is known about the relationship between journal article growth and other forms of scholarly dissemination (e.g., books and monographs). Journal articles are the de facto ... ...

    Abstract The number of scholarly journal articles published each year is growing, but little is known about the relationship between journal article growth and other forms of scholarly dissemination (e.g., books and monographs). Journal articles are the de facto currency of evaluation and prestige in STEM fields, but social scientists routinely publish books as well as articles, representing a unique opportunity to study increased article publications in disciplines with other dissemination options. We studied the publishing activity of social science faculty members in 12 disciplines at 290 Ph.D. granting institutions in the United States between 2011 and 2019, asking: 1) have publication practices changed such that more or fewer books and articles are written now than in the recent past?; 2) has the percentage of scholars actively participating in a particular publishing type changed over time?; and 3) do different age cohorts evince different publication strategies? In all disciplines, journal articles per person increased between 3% and 64% between 2011 and 2019, while books per person decreased by at least 31% and as much as 54%. All age cohorts show increased article authorship over the study period, and early career scholars author more articles per person than the other cohorts in eight disciplines. The article-dominated literatures of the social sciences are becoming increasingly similar to those of STEM disciplines.
    Keywords Medicine ; R ; Science ; Q
    Subject code 070 ; 001
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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    Inter-library loan at ZB MED

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  7. Article: Arthroscopic knots: Suture and knot characterisation of modern polyblend suture materials.

    Savage, Earle / Hurren, Christopher J / Rajmohan, Gayathri Devi / Thomas, William / Page, Richard S

    Heliyon

    2023  Volume 9, Issue 9, Page(s) e19391

    Abstract: Objective: The primary aim of this study was to explore the relationship between the biophysical structure and function of modern suture materials. Particularly the suture's ability to withstand the stressors of surgery and how the material properties ... ...

    Abstract Objective: The primary aim of this study was to explore the relationship between the biophysical structure and function of modern suture materials. Particularly the suture's ability to withstand the stressors of surgery and how the material properties affect knot stability. The secondary aim was to investigate the effect that different knots have on the suture material itself. This study builds on previous research assessing suture and knot characteristics but in modern Ultra High Molecular Weight Polyethylene (UHMWPE) materials currently in widespread clinical use in arthroscopic surgery.
    Methods: Three common UHMWPE sutures and one polyester suture were tested in both a dry and wet state using the Geelong, Nicky's, Surgeon's and Tautline knots. Tensile strength of knots was tested vertically at a 60 mm/min strain rate and 45 mm gauge length. Sutures were tied through a cannula around two 8 mm diameter circular bollards. Testing was conducted in a controlled environment temperature and humidity environment (20 ± 2 °C, 65 ± 2%).
    Results: No one knot type was optimal over all suture types. Mean tensile strength in both a dry and wet state and a low coefficient of variation (CV) in tensile strength in a wet state were considered as an indication of suitability. With Ethibond sutures this was the Geelong knot (CV:4.2%). With Orthocord sutures both the Geelong and Tautline knots (CV:4.2% and CV:11.9% respectively). With FiberWire sutures the Nickys and Tautline knots (CV:22.6% and CV:22.5% respectively). With ForceFiber sutures all four knots exhibited similar wet tensile strength with high variability showing that all should perform in a similar way
    Conclusions: This study demonstrates a statistically significant three-way interaction between polyblend suture materials, the knot and the environment. This has implications for knot security using the tested sutures in different environments, as one knot may not behave the same under all conditions.
    Language English
    Publishing date 2023-08-25
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2023.e19391
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Convection-enhanced delivery of immunomodulatory therapy for high-grade glioma.

    Sperring, Colin P / Argenziano, Michael G / Savage, William M / Teasley, Damian E / Upadhyayula, Pavan S / Winans, Nathan J / Canoll, Peter / Bruce, Jeffrey N

    Neuro-oncology advances

    2023  Volume 5, Issue 1, Page(s) vdad044

    Abstract: The prognosis for glioblastoma has remained poor despite multimodal standard of care treatment, including temozolomide, radiation, and surgical resection. Further, the addition of immunotherapies, while promising in a number of other solid tumors, has ... ...

    Abstract The prognosis for glioblastoma has remained poor despite multimodal standard of care treatment, including temozolomide, radiation, and surgical resection. Further, the addition of immunotherapies, while promising in a number of other solid tumors, has overwhelmingly failed in the treatment of gliomas, in part due to the immunosuppressive microenvironment and poor drug penetrance to the brain. Local delivery of immunomodulatory therapies circumvents some of these challenges and has led to long-term remission in select patients. Many of these approaches utilize convection-enhanced delivery (CED) for immunological drug delivery, allowing high doses to be delivered directly to the brain parenchyma, avoiding systemic toxicity. Here, we review the literature encompassing immunotherapies delivered via CED-from preclinical model systems to clinical trials-and explore how their unique combination elicits an antitumor response by the immune system, decreases toxicity, and improves survival among select high-grade glioma patients.
    Language English
    Publishing date 2023-04-21
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 3009682-0
    ISSN 2632-2498 ; 2632-2498
    ISSN (online) 2632-2498
    ISSN 2632-2498
    DOI 10.1093/noajnl/vdad044
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Arthroscopic knots

    Earle Savage / Christopher J. Hurren / Gayathri Devi Rajmohan / William Thomas / Richard S. Page

    Heliyon, Vol 9, Iss 9, Pp e19391- (2023)

    Suture and knot characterisation of modern polyblend suture materials

    2023  

    Abstract: Objective: The primary aim of this study was to explore the relationship between the biophysical structure and function of modern suture materials. Particularly the suture's ability to withstand the stressors of surgery and how the material properties ... ...

    Abstract Objective: The primary aim of this study was to explore the relationship between the biophysical structure and function of modern suture materials. Particularly the suture's ability to withstand the stressors of surgery and how the material properties affect knot stability. The secondary aim was to investigate the effect that different knots have on the suture material itself. This study builds on previous research assessing suture and knot characteristics but in modern Ultra High Molecular Weight Polyethylene (UHMWPE) materials currently in widespread clinical use in arthroscopic surgery. Methods: Three common UHMWPE sutures and one polyester suture were tested in both a dry and wet state using the Geelong, Nicky's, Surgeon's and Tautline knots. Tensile strength of knots was tested vertically at a 60 mm/min strain rate and 45 mm gauge length. Sutures were tied through a cannula around two 8 mm diameter circular bollards. Testing was conducted in a controlled environment temperature and humidity environment (20 ± 2 °C, 65 ± 2%). Results: No one knot type was optimal over all suture types. Mean tensile strength in both a dry and wet state and a low coefficient of variation (CV) in tensile strength in a wet state were considered as an indication of suitability. With Ethibond sutures this was the Geelong knot (CV:4.2%). With Orthocord sutures both the Geelong and Tautline knots (CV:4.2% and CV:11.9% respectively). With FiberWire sutures the Nickys and Tautline knots (CV:22.6% and CV:22.5% respectively). With ForceFiber sutures all four knots exhibited similar wet tensile strength with high variability showing that all should perform in a similar way invivo. Conclusions: This study demonstrates a statistically significant three-way interaction between polyblend suture materials, the knot and the environment. This has implications for knot security using the tested sutures in different environments, as one knot may not behave the same under all conditions.
    Keywords Arthroscopic knots characterisation ; Knots ; Tensile strength of knots ; Contemporary UHMWPE suture ; Suture and knot characterisation and orthopaedic surgery ; Science (General) ; Q1-390 ; Social sciences (General) ; H1-99
    Subject code 514
    Language English
    Publishing date 2023-09-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  10. Article: A cross-reactive plasmonic sensing array for drinking water assessment.

    Sperling, Justin R / Poursat, Baptiste / Savage, Laurie / Christie, Iain / Cuthill, Calum / Aekbote, Badri L / McGuire, Katie / Karimullah, Affar S / Robbie, Jill / Sloan, William T / Gauchotte-Lindsay, Caroline / Peveler, William J / Clark, Alasdair W

    Environmental science. Nano

    2023  Volume 10, Issue 12, Page(s) 3500–3508

    Abstract: The continuous monitoring of remote drinking water purification systems is a global challenge with direct consequences for human and environmental health. Here, we utilise a "nano-tastebud" sensor comprised of eight chemically-tailored plasmonic ... ...

    Abstract The continuous monitoring of remote drinking water purification systems is a global challenge with direct consequences for human and environmental health. Here, we utilise a "nano-tastebud" sensor comprised of eight chemically-tailored plasmonic metasurfaces, for testing the composition of drinking water. Through undertaking a full chemometric analysis of the water samples and likely contaminants we were able to optimise the sensor specification to create an array of suitable tastebuds. By generating a unique set of optical responses for each water sample, we show that the array-based sensor can differentiate between untreated influent and treated effluent water with over 95% accuracy in flow and can detect compositional changes in distributed modified tap water. Once fully developed, this system could be integrated into water treatment facilities and distribution systems to monitor for changes in water composition.
    Language English
    Publishing date 2023-11-13
    Publishing country England
    Document type Journal Article
    ZDB-ID 2758235-8
    ISSN 2051-8161 ; 2051-8153
    ISSN (online) 2051-8161
    ISSN 2051-8153
    DOI 10.1039/d3en00565h
    Database MEDical Literature Analysis and Retrieval System OnLINE

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