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  1. Article ; Online: Giant parathyroid adenoma: a case report.

    Mahmodlou, Rahim / Sedokani, Amin / Pezeshk, Apameh / Najafinejad, Bita

    Journal of medical case reports

    2022  Volume 16, Issue 1, Page(s) 150

    Abstract: Background: Giant parathyroid adenoma is a type of parathyroid adenoma weighing > 3.5 g and having a size of more than 2 cm.: Case presentation: This report describes giant primary parathyroid adenoma with reference to the literature. We report the ... ...

    Abstract Background: Giant parathyroid adenoma is a type of parathyroid adenoma weighing > 3.5 g and having a size of more than 2 cm.
    Case presentation: This report describes giant primary parathyroid adenoma with reference to the literature. We report the case of a 48-year-old Persian man referred to the clinic with knee and lower back pain. He had a history of mitral valve replacement and several episodes of bilateral nephrolithiasis. After a thorough assessment, a neck mass with a possible thyroid origin was detected, but further assessment showed it was of parathyroid origin. The resected mass was 9 × 6× 4 cm and weighed 122 g, and histopathology showed a giant parathyroid adenoma.
    Conclusion: Giant parathyroid adenomas that weigh more than 110 g and are larger than 8 cm can lead to significant hypercalcemia. Despite giant parathyroid adenomas and high parathyroid hormone levels, a calcium crisis may not always occur in these patients, and the masses may be initially misdiagnosed as a thyroid mass.
    MeSH term(s) Adenoma/diagnostic imaging ; Adenoma/surgery ; Humans ; Hypercalcemia/diagnosis ; Hypercalcemia/etiology ; Male ; Middle Aged ; Parathyroid Hormone ; Parathyroid Neoplasms/diagnosis ; Parathyroid Neoplasms/diagnostic imaging ; Thyroid Gland/pathology
    Chemical Substances Parathyroid Hormone
    Language English
    Publishing date 2022-04-13
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 2269805-X
    ISSN 1752-1947 ; 1752-1947
    ISSN (online) 1752-1947
    ISSN 1752-1947
    DOI 10.1186/s13256-022-03401-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Chronic Perioral Tuberculosis Skin Lesions in a 21-Year-Old Male.

    Gharabaghi, Naser / Sedokani, Amin

    Infection and drug resistance

    2020  Volume 13, Page(s) 3273–3276

    Abstract: Cutaneous tuberculosis is a rare form of tuberculosis infection that may lead to chronic lesions of skin and be missed in diagnosis due to location of the appearance of the lesions. This is a very rare case of peri-oral cutaneous tuberculosis in a 21- ... ...

    Abstract Cutaneous tuberculosis is a rare form of tuberculosis infection that may lead to chronic lesions of skin and be missed in diagnosis due to location of the appearance of the lesions. This is a very rare case of peri-oral cutaneous tuberculosis in a 21-year-old man with no other specific sign of symptoms of tuberculosis infection but mimics signs of
    Keywords covid19
    Language English
    Publishing date 2020-09-25
    Publishing country New Zealand
    Document type Case Reports
    ZDB-ID 2494856-1
    ISSN 1178-6973
    ISSN 1178-6973
    DOI 10.2147/IDR.S260796
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Heroin Intoxication Through Damaged Skin in a 7-Year-Old Girl.

    Delirrad, Mohammad / Sedokani, Amin

    International medical case reports journal

    2020  Volume 13, Page(s) 379–382

    Abstract: Transdermal opioid intoxication has only been reported for pharmaceutical fentanyl and buprenorphine patches. Here, we report a rare case of heroin poisoning through damaged skin. A seven-year-old girl with an impaired level of consciousness and ... ...

    Abstract Transdermal opioid intoxication has only been reported for pharmaceutical fentanyl and buprenorphine patches. Here, we report a rare case of heroin poisoning through damaged skin. A seven-year-old girl with an impaired level of consciousness and difficulty breathing was brought to a local hospital about one hour after burning with boiling water. She had a small second-degree burn on the right elbow. Clinicians were initially unable to obtain any reliable history from relatives about the cause of altered mental status. However, with a clinical suspicion of opioid poisoning, naloxone therapy started, and the patient was moderately improved. She underwent a coma workup; then she was referred to a tertiary care hospital. Further investigation revealed that after the burning, the mother left home to seek for a burn ointment from a neighbor, and the heroin-dependent father sprinkled some heroin powder over the burned area. Heroin was absorbed through the damaged skin and poisoned the child unintentionally. After three days of clinical management, the patient was discharged from the hospital in good condition without any complications. Heroin can be absorbed through damaged skin and cause poisoning. Diagnosis requires strong clinical suspicion, and an appropriate naloxone therapy may be life-saving.
    Language English
    Publishing date 2020-08-26
    Publishing country New Zealand
    Document type Case Reports
    ZDB-ID 2495077-4
    ISSN 1179-142X
    ISSN 1179-142X
    DOI 10.2147/IMCRJ.S259326
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Color Doppler Ultrasonography in Evaluating the Outcomes of Pyeloplasty in Ureteropelvic Junction Obstruction.

    Hamedanchi, Sepehr / Sedokani, Amin

    Research and reports in urology

    2020  Volume 12, Page(s) 53–59

    Abstract: Purpose: To evaluate the accuracy of Color Doppler ultrasonography for diagnosing post pyeloplasty elimination of obstruction in Ureteropelvic Junction Obstruction patients.: Methodology: Patients with the diagnosis of UPJO enrolled in the study and ... ...

    Abstract Purpose: To evaluate the accuracy of Color Doppler ultrasonography for diagnosing post pyeloplasty elimination of obstruction in Ureteropelvic Junction Obstruction patients.
    Methodology: Patients with the diagnosis of UPJO enrolled in the study and underwent open pyeloplasty. Three to 6 months after the operation, patients were recalled and underwent isotope scan as the gold standard test and renal color Doppler ultrasonography to assess the success rate of pyeloplasty.
    Results: A total of 39 patients were evaluated and analyzed. The average follow-up time for patients was 9.1 months. The success rate of surgery in the study population was 100%. The mean RI of the affected side before the operation was 0.69 ± 0.01 and after the pyeloplasty, it reached to 0.65 ± 0.01. The difference between the mean RI of the affected side before and after the operation is 0.04 (P < 0.001). Age, type and severity of obstruction and the technique of surgery did not have any impact on these parameters. The difference between the RI of the affected and healthy side was termed ΔRI. ΔRI before and after the operation was 0.084 and 0.014, respectively. The decrease of ΔRI in the case of pyeloplasty is 0.07 on average (P < 0.001), which can be predicted for pyeloplasty success.
    Discussion: Color Doppler ultrasonography can be used as a non-invasive, fast, non-expensive, and available modality for evaluating the outcome of pyeloplasty instead of the nuclear scan or IVP.
    Language English
    Publishing date 2020-02-24
    Publishing country England
    Document type Journal Article
    ZDB-ID 2649530-2
    ISSN 2253-2447
    ISSN 2253-2447
    DOI 10.2147/RRU.S227046
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Plasmapheresis, Anti-ACE2 and Anti-FcγRII Monoclonal Antibodies: A Possible Treatment for Severe Cases of COVID-19.

    Sedokani, Amin / Feizollahzadeh, Sadegh

    Drug design, development and therapy

    2020  Volume 14, Page(s) 2607–2611

    Abstract: In March 2020, the WHO declared the COVID-19 disease as a pandemic disease. There have been studies on the COVID-19 to find a certain treatment, but yet, there is no certain cure. In this article, we present a possible way to treat severe cases of COVID- ... ...

    Abstract In March 2020, the WHO declared the COVID-19 disease as a pandemic disease. There have been studies on the COVID-19 to find a certain treatment, but yet, there is no certain cure. In this article, we present a possible way to treat severe cases of COVID-19. Based on the previous studies, there are similarities between the spike antigens of SARS-CoV and SARS-CoV-2 viruses. It is expected that these similarities (structural and affinity to the receptor of ACE2) can lead to the same pathophysiological activity of the virus by the use of ACE2 and FcγRII (the antibody-dependent enhancement mechanism). Therefore, we propose a way of washing out (by plasmapheresis) the possible antibodies against the spike protein of the virus out of patients' plasma to stop the antibody-dependent enhancement (ADE)-mediated infection of the immune system cells at the first phase of the treatment and simultaneous use of the anti-ACE2 with anti-FcγRII monoclonal antibodies at the second phase. We propose these procedures for the patients that have no significant response for typical anti-viral, ARDS and conservative therapies, and the disease persists or progresses despite sufficient therapies.
    MeSH term(s) Angiotensin-Converting Enzyme 2 ; Antibodies, Monoclonal/administration & dosage ; Antibodies, Monoclonal/immunology ; Antibodies, Viral/immunology ; Antigens, Viral/immunology ; COVID-19 ; Coronavirus Infections/immunology ; Coronavirus Infections/therapy ; Coronavirus Infections/virology ; Humans ; Pandemics ; Peptidyl-Dipeptidase A/immunology ; Plasmapheresis/methods ; Pneumonia, Viral/immunology ; Pneumonia, Viral/therapy ; Pneumonia, Viral/virology ; Receptors, IgG/immunology ; Severity of Illness Index
    Chemical Substances Antibodies, Monoclonal ; Antibodies, Viral ; Antigens, Viral ; Receptors, IgG ; Peptidyl-Dipeptidase A (EC 3.4.15.1) ; ACE2 protein, human (EC 3.4.17.23) ; Angiotensin-Converting Enzyme 2 (EC 3.4.17.23)
    Keywords covid19
    Language English
    Publishing date 2020-07-06
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2451346-5
    ISSN 1177-8881 ; 1177-8881
    ISSN (online) 1177-8881
    ISSN 1177-8881
    DOI 10.2147/DDDT.S262491
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Giant parathyroid adenoma

    Rahim Mahmodlou / Amin Sedokani / Apameh Pezeshk / Bita Najafinejad

    Journal of Medical Case Reports, Vol 16, Iss 1, Pp 1-

    a case report

    2022  Volume 5

    Abstract: Abstract Background Giant parathyroid adenoma is a type of parathyroid adenoma weighing > 3.5 g and having a size of more than 2 cm. Case presentation This report describes giant primary parathyroid adenoma with reference to the literature. We report the ...

    Abstract Abstract Background Giant parathyroid adenoma is a type of parathyroid adenoma weighing > 3.5 g and having a size of more than 2 cm. Case presentation This report describes giant primary parathyroid adenoma with reference to the literature. We report the case of a 48-year-old Persian man referred to the clinic with knee and lower back pain. He had a history of mitral valve replacement and several episodes of bilateral nephrolithiasis. After a thorough assessment, a neck mass with a possible thyroid origin was detected, but further assessment showed it was of parathyroid origin. The resected mass was 9 × 6× 4 cm and weighed 122 g, and histopathology showed a giant parathyroid adenoma. Conclusion Giant parathyroid adenomas that weigh more than 110 g and are larger than 8 cm can lead to significant hypercalcemia. Despite giant parathyroid adenomas and high parathyroid hormone levels, a calcium crisis may not always occur in these patients, and the masses may be initially misdiagnosed as a thyroid mass.
    Keywords Giant parathyroid adenoma ; Parathormone ; Hypercalcemia ; Bone pain ; Medicine ; R
    Language English
    Publishing date 2022-04-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Thesis ; Online: Plasmapheresis, Anti-ACE2 and Anti-FcγRII Monoclonal Antibodies

    Sedokani, Amin / Feizollahzadeh, Sadegh

    A Possible Treatment for Severe Cases of COVID-19

    2020  

    Abstract: Amin Sedokani,1 Sadegh Feizollahzadeh2 1Cardiology Department, Medical Faculty, Urmia University ... University of Medical Sciences, Urmia, IranCorrespondence: Amin SedokaniCardiology Department ... 5907Fax +98 443 237 2917Email A.sedokani@gmail.comAbstract: In March 2020, the WHO declared the COVID-19 ...

    Abstract Amin Sedokani,1 Sadegh Feizollahzadeh2 1Cardiology Department, Medical Faculty, Urmia University of Medical Sciences, Urmia, Iran; 2Medical Immunology, Laboratory Sciences, School of Allied Medical Sciences, Urmia University of Medical Sciences, Urmia, IranCorrespondence: Amin SedokaniCardiology Department, Medical Faculty, Urmia University of Medical Sciences, 17 Sharivar St., Urmia 571478334, IranTel +98 443237 5907Fax +98 443 237 2917Email A.sedokani@gmail.comAbstract: In March 2020, the WHO declared the COVID-19 disease as a pandemic disease. There have been studies on the COVID-19 to find a certain treatment, but yet, there is no certain cure. In this article, we present a possible way to treat severe cases of COVID-19. Based on the previous studies, there are similarities between the spike antigens of SARS-CoV and SARS-CoV-2 viruses. It is expected that these similarities (structural and affinity to the receptor of ACE2) can lead to the same pathophysiological activity of the virus by the use of ACE2 and FcγRII (the antibody-dependent enhancement mechanism). Therefore, we propose a way of washing out (by plasmapheresis) the possible antibodies against the spike protein of the virus out of patients’ plasma to stop the antibody-dependent enhancement (ADE)-mediated infection of the immune system cells at the first phase of the treatment and simultaneous use of the anti-ACE2 with anti-FcγRII monoclonal antibodies at the second phase. We propose these procedures for the patients that have no significant response for typical anti-viral, ARDS and conservative therapies, and the disease persists or progresses despite sufficient therapies.Keywords: COVID-19, SARS-CoV-2, antibody-dependent enhancement, plasmapheresis, monoclonal antibodies
    Keywords Drug Design ; Development and Therapy ; covid19
    Subject code 616
    Language English
    Publishing date 2020-07-06
    Publisher Dove Press
    Publishing country us
    Document type Article ; Thesis ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Plasmapheresis, Anti-ACE2 and Anti-FcγRII Monoclonal Antibodies

    Sedokani, Amin / Feizollahzadeh, Sadegh

    Drug Design, Development and Therapy

    A Possible Treatment for Severe Cases of COVID-19

    2020  Volume Volume 14, Page(s) 2607–2611

    Keywords Pharmacology ; Drug Discovery ; Pharmaceutical Science ; covid19
    Language English
    Publisher Informa UK Limited
    Publishing country uk
    Document type Article ; Online
    ZDB-ID 2451346-5
    ISSN 1177-8881
    ISSN 1177-8881
    DOI 10.2147/dddt.s262491
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Hemitruncus Arteriosus in a 10-Day-Old Neonate with Patent Ductus Arteriosus and Thrombocytopenia.

    Zolfi-Gol, Ali / Radvar, Mohammad / Sedokani, Amin

    Vascular health and risk management

    2020  Volume 16, Page(s) 99–101

    Abstract: Hemitruncus arteriosus refers to an uncommon congenital cardiovascular abnormality. It usually presents in infancy and leads to the development of pulmonary hypertension, heart failure, and in severe cases maybe death. Herein, we reported hemitruncus ... ...

    Abstract Hemitruncus arteriosus refers to an uncommon congenital cardiovascular abnormality. It usually presents in infancy and leads to the development of pulmonary hypertension, heart failure, and in severe cases maybe death. Herein, we reported hemitruncus arteriosus in a 10-day-old neonate with respiratory distress, patent ductus arteriosus, and thrombocytopenia.
    MeSH term(s) Disease Progression ; Ductus Arteriosus, Patent/complications ; Ductus Arteriosus, Patent/diagnostic imaging ; Ductus Arteriosus, Patent/physiopathology ; Ductus Arteriosus, Patent/therapy ; Fatal Outcome ; Humans ; Infant, Newborn ; Male ; Respiratory Distress Syndrome, Newborn/etiology ; Thrombocytopenia/complications ; Thrombocytopenia/diagnosis ; Thrombocytopenia/therapy ; Truncus Arteriosus, Persistent/complications ; Truncus Arteriosus, Persistent/diagnostic imaging ; Truncus Arteriosus, Persistent/physiopathology ; Truncus Arteriosus, Persistent/therapy
    Language English
    Publishing date 2020-04-01
    Publishing country New Zealand
    Document type Case Reports
    ZDB-ID 2186568-1
    ISSN 1178-2048 ; 1176-6344
    ISSN (online) 1178-2048
    ISSN 1176-6344
    DOI 10.2147/VHRM.S245033
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Plasmapheresis, Anti-ACE2 and Anti-FcγRII Monoclonal Antibodies: A Possible Treatment for Severe Cases of COVID-19

    Sedokani, Amin / Feizollahzadeh, Sadegh

    Drug Des Devel Ther

    Abstract: In March 2020, the WHO declared the COVID-19 disease as a pandemic disease. There have been studies on the COVID-19 to find a certain treatment, but yet, there is no certain cure. In this article, we present a possible way to treat severe cases of COVID- ... ...

    Abstract In March 2020, the WHO declared the COVID-19 disease as a pandemic disease. There have been studies on the COVID-19 to find a certain treatment, but yet, there is no certain cure. In this article, we present a possible way to treat severe cases of COVID-19. Based on the previous studies, there are similarities between the spike antigens of SARS-CoV and SARS-CoV-2 viruses. It is expected that these similarities (structural and affinity to the receptor of ACE2) can lead to the same pathophysiological activity of the virus by the use of ACE2 and FcγRII (the antibody-dependent enhancement mechanism). Therefore, we propose a way of washing out (by plasmapheresis) the possible antibodies against the spike protein of the virus out of patients' plasma to stop the antibody-dependent enhancement (ADE)-mediated infection of the immune system cells at the first phase of the treatment and simultaneous use of the anti-ACE2 with anti-FcγRII monoclonal antibodies at the second phase. We propose these procedures for the patients that have no significant response for typical anti-viral, ARDS and conservative therapies, and the disease persists or progresses despite sufficient therapies.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #683522
    Database COVID19

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