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Article: Editorial: Site specific imaging guidelines in head & neck, and skull base cancers.

Vaish, Richa / Mahajan, Abhishek / Ghosh Laskar, Sarbani / Prabhash, Kumar / Noronha, Vanita / D'Cruz, Anil K

2024 Volume 14, Page(s) 1357215

Language	English
Publishing date	2024-01-18
Publishing country	Switzerland
Document type	Editorial
ZDB-ID	2649216-7
ISSN	2234-943X
ISSN	2234-943X
DOI	10.3389/fonc.2024.1357215
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Article ; Online: Biogas from lignocellulosic feedstock: current status and challenges.

Chettri, Dixita / Verma, Ashwani Kumar / Ghosh, Shilpi / Verma, Anil Kumar

Environmental science and pollution research international

2023

Abstract: The organic wastes and residues generated from agricultural, industrial, and domestic activities have the potential to be converted to bioenergy. One such energy is biogas, which has already been included in rural areas as an alternative cooking energy ... ...

Abstract	The organic wastes and residues generated from agricultural, industrial, and domestic activities have the potential to be converted to bioenergy. One such energy is biogas, which has already been included in rural areas as an alternative cooking energy source and agricultural activities. It is produced via anaerobic digestion of a wide range of organic nutrient sources and is an essential renewable energy source. The factors influencing biogas yield, i.e., the various substrate, their characteristics, pretreatment methods involved, different microbial types, sources, and inoculum properties, are analyzed. Furthermore, the optimization of these parameters, along with fermentation media optimization, such as optimum pH, temperature, and anaerobic digestion strategies, is discussed. Novel approaches of bioaugmentation, co-digestion, phase separation, co-supplementation, nanotechnology, and biorefinery approach have also been explored for biogas production. Finally, the current challenges and prospects of the process are discussed in the review.
Language	English
Publishing date	2023-09-12
Publishing country	Germany
Document type	Journal Article ; Review
ZDB-ID	1178791-0
ISSN	1614-7499 ; 0944-1344
ISSN (online)	1614-7499
ISSN	0944-1344
DOI	10.1007/s11356-023-29805-x
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Article: Genetic diversity, population structure analysis and codon substitutions of Indicine Badri cattle using ddRAD sequencing.

Rahman, Javid Ur / Kumar, Devendra / Singh, Satya Pal / Shahi, Bijendra Narayan / Ghosh, Ashis Kumar / Kumar, Anil / Dar, Aashaq Hussain / Ahmad, Sheikh Firdous / Pathak, Abhishek / Verma, Manish Kumar

3 Biotech

2024 Volume 14, Issue 2, Page(s) 46

Abstract: The present study was carried out on 96 animals representing three distinct colour variants of Badri cattle to investigate the genetic diversity, population structure and substitution mutations in the genetic codons due to single nucleotide variations. ... ...

Abstract	The present study was carried out on 96 animals representing three distinct colour variants of Badri cattle to investigate the genetic diversity, population structure and substitution mutations in the genetic codons due to single nucleotide variations. The DNA samples of 96 Badri cows were genotyped using a double digestion restriction associated DNA (ddRAD) sequencing approach. A standardized bioinformatics pipeline was employed to identify single nucleotide polymorphisms (SNPs), initially detecting 7,168,552 SNPs through alignment with the
Language	English
Publishing date	2024-01-19
Publishing country	Germany
Document type	Journal Article
ZDB-ID	2600522-0
ISSN	2190-5738 ; 2190-572X
ISSN (online)	2190-5738
ISSN	2190-572X
DOI	10.1007/s13205-023-03894-4
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Article ; Online: Tuning the semimetallic charge transport in the Weyl semimetal candidate Eu

Ghosh, Mithun / Bhat, Shwetha G / Pal, Anand / Kumar, P S Anil

Journal of physics. Condensed matter : an Institute of Physics journal

2022 Volume 34, Issue 16

Abstract: We report the stoichiometric epitaxial growth of the ... ...

Abstract	We report the stoichiometric epitaxial growth of the Eu
Language	English
Publishing date	2022-02-21
Publishing country	England
Document type	Journal Article
ZDB-ID	1472968-4
ISSN	1361-648X ; 0953-8984
ISSN (online)	1361-648X
ISSN	0953-8984
DOI	10.1088/1361-648X/ac50da
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Article ; Online: Effect of ivermectin, amitraz and fipronil on midgut epithelium and digestive enzyme profile in Rhipicephalus microplus ticks (Acari: Ixodidae).

Bisht, Nisha / Fular, Ashutosh / Saini, Mohini / Kumar, Satyanshu / Sankar, M / Sharma, Anil Kumar / Ghosh, Srikant

Experimental & applied acarology

2024 Volume 92, Issue 4, Page(s) 851–870

Abstract: Blood feeding and digestion are vital physiological activities essential for the survival and reproduction of ticks. Chemical acaricides viz., ivermectin, amitraz and fipronil, are known to act on the central nervous system, resulting in the mortality of ...

Abstract	Blood feeding and digestion are vital physiological activities essential for the survival and reproduction of ticks. Chemical acaricides viz., ivermectin, amitraz and fipronil, are known to act on the central nervous system, resulting in the mortality of ticks. The present study is focused on the effect of these acaricides on the midgut and gut enzymes of Rhipicephalus microplus. The ultra-thin sections of midgut of ivermectin-treated ticks showed irregular basal membrane and ruptured digestive vesicles. Amitraz treatment resulted in a notable decrease in digestive cells with pleats in the basal membrane, while fipronil-exposed ticks exhibited reduced digestive cells, loss of cellular integrity, and disintegration of the basal membrane and muscle layer. The gut tissue homogenate of ivermectin and fipronil treated ticks showed a significant reduction of cathepsin D level, 76.54 ± 3.20 μg/mL and 92.67 ± 3.72 μg/mL, respectively, as compared to the control group (150.0 ± 3.80 μg/mL). The leucine aminopeptidase level (4.27 ± 0.08 units/mL) was significantly decreased in the ivermectin treated ticks compared to other treatment groups. The acid phosphatase activity (29.16 ± 0.67 μmole/min/L) was reduced in the ivermectin treated group whereas, increased activity was observed in the fipronil and amitraz treated groups. All the treatment groups revealed increased alkaline phosphatase levels (17.47-26.72 μmole/min/L). The present finding suggests that in addition to the established mechanism of action of the tested acaricides on the nervous system, the alterations in the cellular profile of digestive cells and enzymes possibly affect the blood digestion process and thus the synthesis of vital proteins which are essential for vitellogenesis, and egg production in ticks.
MeSH term(s)	Animals ; Rhipicephalus/drug effects ; Rhipicephalus/physiology ; Ivermectin/pharmacology ; Pyrazoles/pharmacology ; Toluidines/pharmacology ; Acaricides/pharmacology ; Female ; Epithelium/drug effects ; Gastrointestinal Tract/drug effects
Chemical Substances	fipronil (QGH063955F) ; amitraz (33IAH5017S) ; Ivermectin (70288-86-7) ; Pyrazoles ; Toluidines ; Acaricides
Language	English
Publishing date	2024-04-20
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	11320-7
ISSN	1572-9702 ; 0168-8162
ISSN (online)	1572-9702
ISSN	0168-8162
DOI	10.1007/s10493-024-00913-8
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Article ; Online: Ectopic overexpression of Eleusine coracana CAX3 confers tolerance to metal and ion stress in yeast and Arabidopsis.

Jamra, Gautam / Ghosh, Soma / Singh, Nidhi / Tripathy, Manas Kumar / Aggarwal, Aparna / Singh, Reema Devi Rajan / Srivastava, Ashish Kumar / Kumar, Anil / Pandey, Girdhar K

Plant physiology and biochemistry : PPB

2024 Volume 211, Page(s) 108613

Abstract: Ionic and metal toxicity in plants is still a global problem for the environment, agricultural productivity and ultimately poses human health threats when these metal ions accumulate in edible organs of plants. Metal and ion transport from cytosol to the ...

Abstract	Ionic and metal toxicity in plants is still a global problem for the environment, agricultural productivity and ultimately poses human health threats when these metal ions accumulate in edible organs of plants. Metal and ion transport from cytosol to the vacuole is considered an important component of metal and ion tolerance and a plant's potential utility in phytoremediation. Finger millet (Eleusine coracana) is an orphan crop but has prominent nutritional value in comparison to other cereals. Previous transcriptomic studies suggested that one of the calcium/proton exchanger (EcCAX3) is strongly upregulated during different developmental stages of spikes development in plant. This finding led us to speculate that high calcium accumulation in the grain might be because of CAX3 function. Moreover, phylogenetic analysis shows that EcCAX3 is more closely related to foxtail millet, sorghum and rice CAX3 protein. To decipher the functional role of EcCAX3, we have adopted complementation of yeast triple mutant K677 (Δpmc1Δvcx1Δcnb1), which has defective calcium transport machinery. Furthermore, metal tolerance assay shows that EcCAX3 expression conferred tolerance to different metal stresses in yeast. The gain-of-function study suggests that EcCAX3 overexpressing Arabidopsis plants shows better tolerance to higher concentration of different metal ions as compared to wild type Col-0 plants. EcCAX3-overexpression transgenic lines exhibits abundance of metal transporters and cation exchanger transporter transcripts under metal stress conditions. Furthermore, EcCAX3-overexpression lines have higher accumulation of macro- and micro-elements under different metal stress. Overall, this finding highlights the functional role of EcCAX3 in the regulation of metal and ion homeostasis and this could be potentially utilized to engineer metal fortification and generation of stress tolerant crops in near future.
Language	English
Publishing date	2024-04-21
Publishing country	France
Document type	Journal Article
ZDB-ID	742978-2
ISSN	1873-2690 ; 0981-9428
ISSN (online)	1873-2690
ISSN	0981-9428
DOI	10.1016/j.plaphy.2024.108613
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Article: Co-Immunization Efficacy of Recombinant Antigens against

Parthasarathi, Balasamudram Chandrasekhar / Kumar, Binod / Bhure, S K / Sharma, Anil Kumar / Manisha / Nagar, Gaurav / Kumar, Sachin / Nandi, Abhijit / Manjunathachar, Haranahally Vasanthachar / Chigure, Gajanan M / Shakya, Mukesh / Sankar, Muthu / Fuente, José de la / Ghosh, Srikant

Pathogens (Basel, Switzerland)

2023 Volume 12, Issue 3

Abstract: The immunoprophylactic management of ticks is the most effective option to control tick infestations and counter spread the acaricide resistance problem worldwide. Several researchers reported an inconsistent efficacy of the single antigen-based ... ...

Abstract	The immunoprophylactic management of ticks is the most effective option to control tick infestations and counter spread the acaricide resistance problem worldwide. Several researchers reported an inconsistent efficacy of the single antigen-based immunization of hosts against different tick species. In the present study, to develop a multi-target immunization protocol, proteins from
Language	English
Publishing date	2023-03-09
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2695572-6
ISSN	2076-0817
ISSN	2076-0817
DOI	10.3390/pathogens12030433
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Article ; Online: Accuracy of assessing 18, 21, and 25 years of age using Olze et al. stage-based system in an Indian sample of young adults.

Kumar, Jitendra / Aggrawal, Anil / Madireddi, Sreenivas / Ghosh, Sujoy / Verma, Mahesh

Legal medicine (Tokyo, Japan)

2022 Volume 57, Page(s) 102061

Abstract: Background: Recently, Olze et al. came up with a staging system based on the radiological changes in the root pulp of the third molar.: Aims & objectives: The current study seeks to ascertain the utility of visibility of the root pulp of the third ... ...

Abstract	Background: Recently, Olze et al. came up with a staging system based on the radiological changes in the root pulp of the third molar. Aims & objectives: The current study seeks to ascertain the utility of visibility of the root pulp of the third molar as a system of forensic age estimation in the Indian population, as suggested by Olze. et al. and to assess the accuracy of cut-off stages for 18, 21, and 25 years of age. Material and methods: Radio-visiogram of 220 Patients (116 males and 104 females) of age 15 to 30 years were examined and staged as per Olze. et al. stage-based system. The statistical methods included descriptive analysis, chi-square test, and Rank-order correlation [rho] test of Spearman. EasyROC web tool was used for ROC analyses and calculating ROC curves (AUCs), likelihood ratio, predictive values, and screening tests for accuracy. Youden's index was used to decide the cut-off stage for the different age groups. Results: Specificity close to 100% was observed among both the Sex for cut-off levels 1, 2, and 3 among 18, 21, and 25 years of age correspondingly with minimal Type II error. Inter andIntraobservations with a kappa value of 0.66 and 0.65, respectively, indicate good agreement. Conclusion: Olze's third molar root pulp 1, 2, and 3 stages can be used as an optimal cut-off for the 18, 21, and 25-year-old thresholds correspondingly with high specificity for both the sexes for age estimation among the Indian population.
MeSH term(s)	Adolescent ; Adult ; Age Determination by Teeth/methods ; Female ; Humans ; Male ; Molar, Third ; ROC Curve ; Radiography, Panoramic ; Tooth Root ; Young Adult
Language	English
Publishing date	2022-04-06
Publishing country	Ireland
Document type	Journal Article
ZDB-ID	2019555-2
ISSN	1873-4162 ; 1344-6223
ISSN (online)	1873-4162
ISSN	1344-6223
DOI	10.1016/j.legalmed.2022.102061
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Article ; Online: Genome-wide identification and annotation of SNPs and their mapping in candidate genes related to milk production and fertility traits in Badri cattle.

Rahman, Javid Ur / Kumar, Devendra / Singh, Satya Pal / Shahi, Bijendra Narayan / Ghosh, Ashis Kumar / Verma, Manish Kumar / Pathak, Abhishek / Dar, Aashaq Hussain / Kumar, Anil / Sharma, Rabendra Kumar

Tropical animal health and production

2023 Volume 55, Issue 2, Page(s) 117

Abstract: This study was conducted in Badri cattle using a double digest restriction-site associated DNA sequencing approach. The study aimed to identify and annotate high confidence single nucleotide polymorphisms (SNPs) and their mapping in candidate genes ... ...

Abstract	This study was conducted in Badri cattle using a double digest restriction-site associated DNA sequencing approach. The study aimed to identify and annotate high confidence single nucleotide polymorphisms (SNPs) and their mapping in candidate genes related to production and fertility in dairy cattle. A total of 7,168,552 genome-wide SNPs were initially identified in Badri cattle by alignment with the Bos indicus reference genome. After filtration of SNPs, 65,483 high confidence SNPs were retained and further used for downstream analysis. Annotation of high confidence SNPs revealed 99.197% SNPs had modifier impact, 0.326% SNPs were low impact, 0.036% were high impact, and 0.441% were moderate impact SNPs. Most SNPs in Badri cattle were found in intergenic, transcript and intronic regions. The candidate genes for milk production PRKCE, ABCG2, GHR, EPS8, CAST and NRXN1 were found to harbour maximum high confidence variants. Among candidate genes for fertility in cattle, ATP2B1, SOX5, WDR27, ARHGAP12, CACNA1D, ANKRD6, GRIA3, ZNF521 and CAST822 have maximum high confidence variants mapped in them. The SNPs found mapped in the candidate genes will be important genetic tools in the search for phenotype-modifying nucleotide changes and will aid in formulating relevant genetic improvement programmes for dairy cattle.
MeSH term(s)	Animals ; Cattle/genetics ; Fertility/genetics ; Genome-Wide Association Study/veterinary ; Milk ; Phenotype ; Polymorphism, Single Nucleotide ; Lactation/genetics
Language	English
Publishing date	2023-03-16
Publishing country	United States
Document type	Journal Article
ZDB-ID	603363-5
ISSN	1573-7438 ; 0049-4747
ISSN (online)	1573-7438
ISSN	0049-4747
DOI	10.1007/s11250-023-03535-1
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Article ; Online: Acaricides resistance in Rhipicephalus microplus and expression profile of ABC-transporter genes in the sampled populations.

Shakya, Mukesh / Sharma, Anil Kumar / Kumar, Sachin / Upadhaya, Deepak / Nagar, Gaurav / Singh, Kaushlendra / M, Sankar / Ghosh, Srikant

Experimental parasitology

2023 Volume 252, Page(s) 108584

Abstract: Currently, livestock owners manage tick infestations using chemicals, but the method is increasingly losing effectiveness as resistant tick populations have established in the field conditions. Thus, to develop effective tick management strategies, ... ...

Abstract	Currently, livestock owners manage tick infestations using chemicals, but the method is increasingly losing effectiveness as resistant tick populations have established in the field conditions. Thus, to develop effective tick management strategies, monitoring of resistance in most predominant tick species, Rhipicephalus microplus was targeted. The ticks were collected from eleven districts of Madhya Pradesh and one district of Punjab and tested against deltamethrin (DLM), cypermethrin (CYP), coumaphos (CMP), ivermectin (IVM) and fipronil (FIP), through adult immersion and larval packet tests. The field isolates were highly resistant to DLM [Resistance factor (RF) = 3.98-38.84]. Against CYP, resistance was observed in BWN (Barwani; RF = 2.81) and MND (Mandsaur; RF = 3.23) isolates. Surprisingly, most of the isolates were susceptible to CMP (0.34-1.58). Emerging level of resistance against IVM (1.05-4.98) and FIP (0.40-2.18) was also observed in all the isolates. Significantly elevated production of esterases (p < 0.01) was 90% correlated with RF of DLM while no positive correlation between production of monooxygenase and Glutathione S-transferase with RF to DLM was noted. Multiple sequence analysis of S4-5 linker region of the sodium channel gene of all the isolates revealed a point mutation at 190th position (C190A) which is associated with DLM resistance. Treatment of resistant LDH (Ludhiana) isolate with IVM resulted in upregulation of RmABCC2 gene and insignificant upregulation of RmABCC1 and RmABCB10 genes indicating the probability of linking IVM resistance with over-expression of RmABCC2 gene. The possible tick management strategies are discussed.
MeSH term(s)	Animals ; Acaricides/pharmacology ; Rhipicephalus/genetics ; ATP-Binding Cassette Transporters/genetics ; ATP-Binding Cassette Transporters/pharmacology ; Insecticide Resistance/genetics ; Ivermectin/pharmacology ; Pyrethrins/pharmacology
Chemical Substances	Acaricides ; ATP-Binding Cassette Transporters ; Ivermectin (70288-86-7) ; cypermethrin (1TR49121NP) ; Pyrethrins
Language	English
Publishing date	2023-07-18
Publishing country	United States
Document type	Journal Article
ZDB-ID	391089-1
ISSN	1090-2449 ; 0014-4894
ISSN (online)	1090-2449
ISSN	0014-4894
DOI	10.1016/j.exppara.2023.108584
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