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  1. Book: Sensorimotor rehabilitation

    Dancause, Numa / Nadeau, Sylvie / Rossignol, Serge

    at the crossroads of basic and clinical sciences

    (Progress in brain research ; 218)

    2015  

    Author's details ed. by Numa Dancause ; Sylvie Nadeau ; Serge Rossignol
    Series title Progress in brain research ; 218
    Collection
    Keywords Sensory integration dysfunction/Patients/Rehabilitation ; Sensorimotor integration
    Subject code 616.83
    Language English
    Size XX, 449 S. : Ill., graph. Darst., 24 cm
    Edition 1. ed.
    Publisher Elsevier
    Publishing place Amsterdam u.a.
    Publishing country Netherlands
    Document type Book
    HBZ-ID HT018637297
    ISBN 978-0-444-63565-5 ; 0-444-63565-3
    Database Catalogue ZB MED Medicine, Health

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  2. Article: Barriers and facilitators to the HPV vaccine: a multicenter qualitative study of French general practitioners.

    Tron, Arthur / Schlegel, Vincent / Pinot, Juliette / Bruel, Sébastien / Ecollan, Marie / Bel, Josselin Le / Rossignol, Louise / Gauchet, Aurélie / Gagneux-Brunon, Amandine / Mueller, Judith / Banaszuk, Anne-Sophie / Thilly, Nathalie / Gilberg, Serge / Partouche, Henri

    Archives of public health = Archives belges de sante publique

    2024  Volume 82, Issue 1, Page(s) 2

    Abstract: Background: In France, human papillomavirus (HPV) vaccination coverage is low, with 30.7% of 17-year-old girls having received a complete HPV vaccination schedule in 2020.: Aim: To determine the perspective and behaviors of general practitioners (GPs) ...

    Abstract Background: In France, human papillomavirus (HPV) vaccination coverage is low, with 30.7% of 17-year-old girls having received a complete HPV vaccination schedule in 2020.
    Aim: To determine the perspective and behaviors of general practitioners (GPs) regarding HPV vaccination with their patients and if a reluctance is observed.
    Design and setting: A qualitative study based on semi-directed individual interviews was conducted between December 2019 and December 2020. A representative sample of GPs with various profiles were included in 4 French regions.
    Method: A purposive sampling was used and interviews were continued until data saturation was reached. The analysis was based on the grounded theory.
    Results: Twenty-six GPs aged 29-66 years were interviewed. The measures taken by the French health authorities (lowering the target age, reimbursing the vaccine, extending the target population to boys) were perceived as facilitators. The reported barriers were organizational, due to low attendance of adolescents, and relational, mainly due to parental vaccine hesitancy. Physicians had to deal with fears about the perceived risks and concerns about sexuality conveyed by HPV vaccination and linked to the socio-cultural characteristics of the families. Physicians developed strategies, including scientific knowledge mobilization, empowerment of families by promoting health through prevention, repetition of the vaccination proposals, personal experience and relationship. Different practices were identified according to three GP typologies: effective, convinced but unpersuasive, and reluctant physicians.
    Conclusion: Based on these results, specific interventions, including communication techniques, especially for hesitant or unpersuasive physicians, are needed to enable GPs to become more effective.
    Language English
    Publishing date 2024-01-04
    Publishing country England
    Document type Journal Article
    ZDB-ID 1117688-x
    ISSN 2049-3258 ; 0778-7367 ; 0003-9578
    ISSN (online) 2049-3258
    ISSN 0778-7367 ; 0003-9578
    DOI 10.1186/s13690-023-01227-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Recovery of locomotion in cats after severe contusion of the low thoracic spinal cord.

    Delivet-Mongrain, Hugo / Dea, Melvin / Gossard, Jean-Pierre / Rossignol, Serge

    Journal of neurophysiology

    2020  Volume 123, Issue 4, Page(s) 1504–1525

    Abstract: Large bilateral contusions of the T10 thoracic spinal cord were performed in 16 adult cats using a calibrated impactor. EMG and video recordings allowed weekly assessments of key locomotor parameters during treadmill training for 5 wk. Thirty-five days ... ...

    Abstract Large bilateral contusions of the T10 thoracic spinal cord were performed in 16 adult cats using a calibrated impactor. EMG and video recordings allowed weekly assessments of key locomotor parameters during treadmill training for 5 wk. Thirty-five days postcontusion, several hindlimb locomotor parameters were very similar to the prelesion ones despite some long-term deficits such as paw drag and disrupted fore-hindlimb coupling. Nine out of ten tested cats could step over obstacles placed on the treadmill. Acute electrophysiological experiments showed viable connectivity between segments rostral and caudal to the contusion. At the fifth postcontusion week, a complete spinalization was performed at T13 in 10 cats and all expressed remarkable bilateral hindlimb locomotion within 24-72 h. From our histological evaluation, we concluded that only a small percentage (~10%) of spinal cord pathways was necessary to initiate and maintain a voluntary quadrupedal locomotor pattern on a treadmill and even to negotiate obstacles. Our findings suggest that hindlimb stepping largely resulted from the activity of spinal locomotor circuits, which gradually recovered autonomy week after week. Our histological and electrophysiological evidence indicated that the persistence of specific deficits or else the maintenance of specific functions was related to the integrity of specific supraspinal and propriospinal pathways. The conclusion is that the recovery of locomotion after large spinal contusions depends on a homeostatic recalibration of a tripartite control system involving interactions between spinal circuits (central pattern generator), supraspinal influences, and sensory feedback activated through locomotor training.
    MeSH term(s) Animals ; Behavior, Animal/physiology ; Cats ; Central Pattern Generators/physiology ; Contusions/physiopathology ; Electromyography ; Feedback, Sensory/physiology ; Female ; Hindlimb/physiopathology ; Neural Pathways/physiopathology ; Physical Conditioning, Animal/physiology ; Practice, Psychological ; Spinal Cord Injuries/physiopathology ; Thoracic Vertebrae ; Walking/physiology
    Language English
    Publishing date 2020-02-26
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 80161-6
    ISSN 1522-1598 ; 0022-3077
    ISSN (online) 1522-1598
    ISSN 0022-3077
    DOI 10.1152/jn.00498.2019
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Barriers and facilitators to the HPV vaccine

    Arthur Tron / Vincent Schlegel / Juliette Pinot / Sébastien BRUEL / Marie Ecollan / Josselin Le Bel / Louise Rossignol / Aurélie Gauchet / Amandine Gagneux-Brunon / Judith Mueller / Anne-Sophie Banaszuk / Nathalie Thilly / Serge Gilberg / Henri Partouche

    Archives of Public Health, Vol 82, Iss 1, Pp 1-

    a multicenter qualitative study of French general practitioners

    2024  Volume 10

    Abstract: Abstract Background In France, human papillomavirus (HPV) vaccination coverage is low, with 30.7% of 17-year-old girls having received a complete HPV vaccination schedule in 2020. Aim To determine the perspective and behaviors of general practitioners ( ... ...

    Abstract Abstract Background In France, human papillomavirus (HPV) vaccination coverage is low, with 30.7% of 17-year-old girls having received a complete HPV vaccination schedule in 2020. Aim To determine the perspective and behaviors of general practitioners (GPs) regarding HPV vaccination with their patients and if a reluctance is observed. Design and setting A qualitative study based on semi-directed individual interviews was conducted between December 2019 and December 2020. A representative sample of GPs with various profiles were included in 4 French regions. Method A purposive sampling was used and interviews were continued until data saturation was reached. The analysis was based on the grounded theory. Results Twenty-six GPs aged 29–66 years were interviewed. The measures taken by the French health authorities (lowering the target age, reimbursing the vaccine, extending the target population to boys) were perceived as facilitators. The reported barriers were organizational, due to low attendance of adolescents, and relational, mainly due to parental vaccine hesitancy. Physicians had to deal with fears about the perceived risks and concerns about sexuality conveyed by HPV vaccination and linked to the socio-cultural characteristics of the families. Physicians developed strategies, including scientific knowledge mobilization, empowerment of families by promoting health through prevention, repetition of the vaccination proposals, personal experience and relationship. Different practices were identified according to three GP typologies: effective, convinced but unpersuasive, and reluctant physicians. Conclusion Based on these results, specific interventions, including communication techniques, especially for hesitant or unpersuasive physicians, are needed to enable GPs to become more effective.
    Keywords Vaccine hesitancy ; Mass vaccination ; Vaccination refusal ; Papillomavirus infections ; Primary prevention ; General practice ; Public aspects of medicine ; RA1-1270
    Subject code 360
    Language English
    Publishing date 2024-01-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Towards a Multi-Pixel Photon-to-Digital Converter for Time-Bin Quantum Key Distribution.

    Carrier, Simon / Labrecque-Dias, Michel / Tannous, Ramy / Gendron, Pascal / Nolet, Frédéric / Roy, Nicolas / Rossignol, Tommy / Vachon, Frédéric / Parent, Samuel / Jennewein, Thomas / Charlebois, Serge / Pratte, Jean-François

    Sensors (Basel, Switzerland)

    2023  Volume 23, Issue 7

    Abstract: We present an integrated single-photon detection device custom designed for quantum key distribution (QKD) with time-bin encoded single photons. We implemented and demonstrated a prototype photon-to-digital converter (PDC) that integrates an 8 × 8 single- ...

    Abstract We present an integrated single-photon detection device custom designed for quantum key distribution (QKD) with time-bin encoded single photons. We implemented and demonstrated a prototype photon-to-digital converter (PDC) that integrates an 8 × 8 single-photon avalanche diode (SPAD) array with on-chip digital signal processing built in TSMC 65 nm CMOS. The prototype SPADs are used to validate the QKD functionalities with an array of time-to-digital converters (TDCs) to timestamp and process the photon detection events. The PDC uses window gating to reject noise counts and on-chip processing to sort the photon detections into respective time-bins. The PDC prototype achieved a 22.7 ps RMS timing resolution and demonstrated operation in a time-bin setup with 158 ps time-bins at an optical wavelength of 410 nm. This PDC can therefore be an important building block for a QKD receiver and enables compact and robust time-bin QKD systems with imaging detectors.
    Language English
    Publishing date 2023-03-23
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s23073376
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Plasticity of connections underlying locomotor recovery after central and/or peripheral lesions in the adult mammals.

    Rossignol, Serge

    Philosophical transactions of the Royal Society of London. Series B, Biological sciences

    2006  Volume 361, Issue 1473, Page(s) 1647–1671

    Abstract: This review discusses some aspects of plasticity of connections after spinal injury in adult animal models as a basis for functional recovery of locomotion. After reviewing some pitfalls that must be avoided when claiming functional recovery and the ... ...

    Abstract This review discusses some aspects of plasticity of connections after spinal injury in adult animal models as a basis for functional recovery of locomotion. After reviewing some pitfalls that must be avoided when claiming functional recovery and the importance of a conceptual framework for the control of locomotion, locomotor recovery after spinal lesions, mainly in cats, is summarized. It is concluded that recovery is partly due to plastic changes within the existing spinal locomotor networks. Locomotor training appears to change the excitability of simple reflex pathways as well as more complex circuitry. The spinal cord possesses an intrinsic capacity to adapt to lesions of central tracts or peripheral nerves but, as a rule, adaptation to lesions entails changes at both spinal and supraspinal levels. A brief summary of the spinal capacity of the rat, mouse and human to express spinal locomotor patterns is given, indicating that the concepts derived mainly from work in the cat extend to other adult mammals. It is hoped that some of the issues presented will help to evaluate how plasticity of existing connections may combine with and potentiate treatments designed to promote regeneration to optimize remaining motor functions.
    MeSH term(s) Aging/physiology ; Animals ; Motor Activity/physiology ; Neuronal Plasticity/physiology ; Spinal Cord Injuries/metabolism
    Language English
    Publishing date 2006-08-29
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 208382-6
    ISSN 1471-2970 ; 0962-8436 ; 0080-4622 ; 0264-3839
    ISSN (online) 1471-2970
    ISSN 0962-8436 ; 0080-4622 ; 0264-3839
    DOI 10.1098/rstb.2006.1889
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Book: Sensorimotor rehabilitation

    Dancause, Numa / Nadeau, Sylvie / Rossignol, Serge

    at the crossroads of basic and clinical sciences

    (Progress in brain research ; 218)

    2015  

    Abstract: ... ...

    Author's details ed. by Numa Dancause
    Series title Progress in brain research ; 218
    Abstract Literaturangaben
    Language English
    Size XX, 449 S., Ill., graph. Darst.
    Edition 1. ed.
    Publisher Elsevier
    Publishing place Amsterdam u.a.
    Document type Book
    ISBN 9780444635655 ; 0444635653
    Database Former special subject collection: coastal and deep sea fishing

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  8. Article ; Online: A dual spinal cord lesion paradigm to study spinal locomotor plasticity in the cat.

    Martinez, Marina / Rossignol, Serge

    Annals of the New York Academy of Sciences

    2013  Volume 1279, Page(s) 127–134

    Abstract: After a complete spinal cord injury (SCI) at the lowest thoracic level (T13), adult cats trained to walk on a treadmill can recover hindlimb locomotion within 2-3 weeks, resulting from the activity of a spinal circuitry termed the central pattern ... ...

    Abstract After a complete spinal cord injury (SCI) at the lowest thoracic level (T13), adult cats trained to walk on a treadmill can recover hindlimb locomotion within 2-3 weeks, resulting from the activity of a spinal circuitry termed the central pattern generator (CPG). The role of this spinal circuitry in the recovery of locomotion after partial SCIs, when part of descending pathways can still access the CPG, is not yet fully understood. Using a dual spinal lesion paradigm (first hemisection at T10 followed three weeks after by a complete spinalization at T13), we showed that major changes occurred in this locomotor spinal circuitry. These plastic changes at the spinal cord level could participate in the recovery of locomotion after partial SCI. This short review describes the main findings of this paradigm in adult cats.
    MeSH term(s) Animals ; Biomedical Research/methods ; Cats ; Central Pattern Generators/pathology ; Central Pattern Generators/physiology ; Disease Models, Animal ; Models, Biological ; Neuronal Plasticity/physiology ; Recovery of Function/physiology ; Spinal Cord/pathology ; Spinal Cord/physiopathology ; Spinal Cord Injuries/pathology
    Language English
    Publishing date 2013-03
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 211003-9
    ISSN 1749-6632 ; 0077-8923
    ISSN (online) 1749-6632
    ISSN 0077-8923
    DOI 10.1111/j.1749-6632.2012.06823.x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Book ; Conference proceedings: Sensorimotor rehabilitation

    Dancause, Numa / Nadeau, Sylvie / Rossignol, Serge

    at the crossroads of basic and clinical sciences

    (Progress in brain research, ; volume 218)

    2015  

    Event/congress Rehabilitation: At the Crossroads of Basic and Clinical Sciences (Symposium) (2014, MontréalQuébec)
    Author's details edited by Numa Dancause, Sylvie Nadeau, Serge Rossignol
    Series title Progress in brain research, ; volume 218
    MeSH term(s) Sensation Disorders/rehabilitation ; Movement Disorders/rehabilitation ; Spinal Cord Injuries/rehabilitation ; Gait Disorders, Neurologic/rehabilitation ; Sensorimotor Cortex/physiopathology
    Language English
    Size xx, 449 pages :, illustrations ;, 25 cm.
    Edition First edition.
    Document type Book ; Conference proceedings
    Note "This book regroups the proceedings of a Symposium held in May 2014 in Montreal entitled 'Rehabilitation: At the Crossroads of Basic and Clinical Sciences'."--P. xix.
    ISBN 9780444635655 ; 0444635653
    Database Catalogue of the US National Library of Medicine (NLM)

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  10. Article: Locomotion and its recovery after spinal injury in animal models.

    Rossignol, Serge

    Neurorehabilitation and neural repair

    2002  Volume 16, Issue 2, Page(s) 201–206

    MeSH term(s) Animals ; Cats ; Humans ; Locomotion/physiology ; Models, Animal ; Spinal Cord Injuries/physiopathology ; Spinal Cord Injuries/rehabilitation
    Language English
    Publishing date 2002-06
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 1491637-x
    ISSN 1552-6844 ; 1545-9683 ; 0888-4390
    ISSN (online) 1552-6844
    ISSN 1545-9683 ; 0888-4390
    DOI 10.1177/0888439002016002002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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