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  1. Book: Platelets and megakaryocytes / Volume 4

    Gibbins, Jonathan M.

    (Methods in molecular biology ; 1812 ; Springer protocols)

    2018  

    Author's details ed. by Jonathan M. Gibbins
    Series title Methods in molecular biology ; 1812
    Springer protocols
    Platelets and megakaryocytes
    Collection Platelets and megakaryocytes
    Language English
    Size xi, 290 Seiten, Illustrationen
    Publishing country United States
    Document type Book
    HBZ-ID HT019984525
    ISBN 978-1-49398-584-5 ; 9781493985852 ; 1-49398-584-1 ; 149398585X
    Database Catalogue ZB MED Medicine, Health

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  2. Article ; Online: Adding fuel to the flames in preeclampsia: the platelet connection.

    Gibbins, Jonathan M

    Journal of thrombosis and haemostasis : JTH

    2023  Volume 21, Issue 7, Page(s) 1750–1752

    MeSH term(s) Pregnancy ; Female ; Humans ; Pre-Eclampsia ; Blood Platelets
    Language English
    Publishing date 2023-05-30
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 2112661-6
    ISSN 1538-7836 ; 1538-7933
    ISSN (online) 1538-7836
    ISSN 1538-7933
    DOI 10.1016/j.jtha.2023.03.031
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book: Platelets and megakaryocytes / 3

    Gibbins, Jonathan M.

    (Methods in molecular biology ; 788)

    2012  

    Author's details ed. by Jonathan M. Gibbins
    Series title Methods in molecular biology ; 788
    Platelets and megakaryocytes
    Collection Platelets and megakaryocytes
    Language English
    Size XIV, 409 S. : Ill., graph. Darst.
    Publisher Humana Press
    Publishing place Totowa, NJ
    Publishing country United States
    Document type Book
    HBZ-ID HT016889634
    ISBN 978-1-61779-306-6 ; 9781617793073 ; 1-61779-306-X ; 1617793078
    Database Catalogue ZB MED Medicine, Health

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  4. Article ; Online: Evidence that inositol 1,4,5-trisphosphate 3-kinase and inositol 1,3,4,5-tetrakisphosphate are negative regulators of platelet function.

    Authi, Kalwant S / Khan, Sabeeya / Gibbins, Jonathan M / Brain, Susan D

    Research and practice in thrombosis and haemostasis

    2024  Volume 8, Issue 1, Page(s) 102326

    Abstract: Background: Inositol 1,3,4,5-tetrakisphosphate (IP: Objectives: To better elucidate a function for IP: Methods: Human platelets were utilized in whole blood for thrombus formation, in platelet-rich plasma and washed suspensions for aggregation, ... ...

    Abstract Background: Inositol 1,3,4,5-tetrakisphosphate (IP
    Objectives: To better elucidate a function for IP
    Methods: Human platelets were utilized in whole blood for thrombus formation, in platelet-rich plasma and washed suspensions for aggregation, and for Ca
    Results: GNF362-enhanced platelet aggregation stimulated by low concentrations of ADP, collagen, thrombin, U46619, and thrombus formation in collagen-coated capillaries. GNF362 induced a transient elevation of Ca
    Conclusion: ITPK and IP
    Language English
    Publishing date 2024-01-26
    Publishing country United States
    Document type Journal Article
    ISSN 2475-0379
    ISSN (online) 2475-0379
    DOI 10.1016/j.rpth.2024.102326
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Book: Platelets and megakaryocytes / 2

    Gibbins, Jonathan M.

    (Methods in molecular biology ; 273)

    2004  

    Author's details ed. by Jonathan M. Gibbins
    Series title Methods in molecular biology ; 273
    Platelets and megakaryocytes
    Collection Platelets and megakaryocytes
    Language English
    Size XIX, 503 S. : Ill., graph. Darst.
    Publisher Humana Press
    Publishing place Totowa, NJ
    Publishing country United States
    Document type Book
    HBZ-ID HT013973346
    ISBN 1-58829-011-5 ; 978-1-58829-011-3
    Database Catalogue ZB MED Medicine, Health

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  6. Book: Platelets and megakaryocytes / 1

    Gibbins, Jonathan M.

    (Methods in molecular biology ; 272)

    2004  

    Author's details ed. by Jonathan M. Gibbins
    Series title Methods in molecular biology ; 272
    Platelets and megakaryocytes
    Collection Platelets and megakaryocytes
    Language English
    Publisher Humana Press
    Publishing place Totowa, NJ
    Publishing country United States
    Document type Book
    HBZ-ID HT013973333
    ISBN 1-58829-101-4 ; 978-1-58829-101-1
    Database Catalogue ZB MED Medicine, Health

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  7. Article ; Online: Thiol Isomerases Orchestrate Thrombosis and Hemostasis.

    Gaspar, Renato Simões / Gibbins, Jonathan M

    Antioxidants & redox signaling

    2021  Volume 35, Issue 13, Page(s) 1116–1133

    Abstract: Significance: ...

    Abstract Significance:
    MeSH term(s) Animals ; Hemostasis ; Humans ; Membrane Proteins/metabolism ; Thioredoxins/metabolism ; Thrombosis/metabolism
    Chemical Substances Membrane Proteins ; TMX1 protein, human ; Thioredoxins (52500-60-4)
    Language English
    Publishing date 2021-06-21
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 1483836-9
    ISSN 1557-7716 ; 1523-0864
    ISSN (online) 1557-7716
    ISSN 1523-0864
    DOI 10.1089/ars.2021.0086
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Book ; Collection: Platelets and megakaryocytes

    Gibbins, Jonathan M.

    (Methods in molecular biology ; ...)

    2004  

    Author's details ed. by Jonathan M. Gibbins
    Series title Methods in molecular biology
    ...
    Keywords Blood Platelets / physiology ; Megakaryocytes / physiology ; Histological Techniques
    Language English
    Dates of publication 2004-9999
    Publisher Humana Press
    Publishing place Totowa, NJ
    Publishing country United States
    Document type Book ; Collection (display volumes)
    HBZ-ID HT013973323
    Database Catalogue ZB MED Medicine, Health

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  9. Article: Activation of Human Platelets by

    Waller, Amie K / Birch, Katie / Gibbins, Jonathan M / Clarke, Simon R

    Pathogens (Basel, Switzerland)

    2022  Volume 11, Issue 11

    Abstract: Infection ... ...

    Abstract Infection by
    Language English
    Publishing date 2022-10-26
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2695572-6
    ISSN 2076-0817
    ISSN 2076-0817
    DOI 10.3390/pathogens11111237
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Exploring the constituent mechanisms of hepatitis: a dynamical systems approach.

    Dunster, Joanne L / Gibbins, Jonathan M / Nelson, Martin R

    Mathematical medicine and biology : a journal of the IMA

    2022  Volume 40, Issue 1, Page(s) 24–48

    Abstract: Hepatitis is the term used to describe inflammation in the liver. It is associated with a high rate of mortality, but the underlying disease mechanisms are not completely understood and treatment options are limited. We present a mathematical model of ... ...

    Abstract Hepatitis is the term used to describe inflammation in the liver. It is associated with a high rate of mortality, but the underlying disease mechanisms are not completely understood and treatment options are limited. We present a mathematical model of hepatitis that captures the complex interactions between hepatocytes (liver cells), hepatic stellate cells (cells in the liver that produce hepatitis-associated fibrosis) and the immune components that mediate inflammation. The model is in the form of a system of ordinary differential equations. We use numerical techniques and bifurcation analysis to characterize and elucidate the physiological mechanisms that dominate liver injury and its outcome to a healthy or unhealthy, chronic state. This study reveals the complex interactions between the multiple cell types and mediators involved in this complex disease and highlights potential problems in targeting inflammation in the liver therapeutically.
    MeSH term(s) Humans ; Liver ; Hepatitis/metabolism ; Hepatocytes/metabolism ; Inflammation ; Systems Analysis
    Language English
    Publishing date 2022-10-02
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2119786-6
    ISSN 1477-8602 ; 0265-0746 ; 1477-8599
    ISSN (online) 1477-8602
    ISSN 0265-0746 ; 1477-8599
    DOI 10.1093/imammb/dqac013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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