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  1. Article ; Online: Atypical Varicella-Zoster Virus Reactivation: A Case Report.

    Salvotti, Francesca / Trapletti, Simone / Chiarini, Giulia / Castellano, Maurizio / Muiesan, Maria Lorenza

    European journal of case reports in internal medicine

    2023  Volume 10, Issue 9, Page(s) 3945

    Abstract: Varicella-zoster virus (VZV) commonly causes benign skin manifestations in children; it then establishes a latent infection and may reactivate, causing herpes zoster. The most common zoster complication is postherpetic neuralgia, but complications can ... ...

    Abstract Varicella-zoster virus (VZV) commonly causes benign skin manifestations in children; it then establishes a latent infection and may reactivate, causing herpes zoster. The most common zoster complication is postherpetic neuralgia, but complications can also occur without a rash. VZV infection may cause neurological manifestations and even vasculopathy may occur, in both primary and reactivated VZV infection. Thrombotic complications are mainly described in children, while a few case reports have described cerebral venous sinus thrombosis (CVST), deep-vein thrombosis of the lower limbs and pulmonary embolism in adults. In this article we report the case of a young woman who developed systemic thromboembolic sequelae due to a hypercoagulable state following VZV reactivation. She had deep venous lower-limb thrombosis extended to the inferior vena cava (IVC), massive pulmonary embolism and CVST. Moreover, VZV reactivation caused an acute hepatitis and clinical manifestations suggesting viral encephalitis.
    Learning points: Varicella-zoster virus (VZV) commonly causes self-limiting skin manifestation, but even neurological manifestations and thrombotic complications may occur.Only few isolated cases of VZV-related cerebral venous sinus thrombosis (CVST) and other types of deep-vein thrombosis have been reported in adults.Early diagnosis of VZV-related thrombosis and prompt anticoagulant and antiviral therapy can prevent a potentially fatal outcome and produce a good prognosis.
    Language English
    Publishing date 2023-08-11
    Publishing country Italy
    Document type Journal Article
    ISSN 2284-2594
    ISSN (online) 2284-2594
    DOI 10.12890/2023_003945
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Platypnoea-Orthodeoxia Syndrome in COVID-19.

    Salvotti, Francesca / Poiatti, Francesco / Bressa, Stefano / Montani, Giovanni / Nardin, Matteo / Rizzoni, Damiano

    European journal of case reports in internal medicine

    2021  Volume 8, Issue 10, Page(s) 2849

    Abstract: Platypnoea-orthodeoxia syndrome (POS) is a rare disorder and its pathophysiology has puzzled clinicians for years. Few cases of POS are described in COVID-19 patients in the literature, with a high variability of conditions related to the syndrome. In ... ...

    Abstract Platypnoea-orthodeoxia syndrome (POS) is a rare disorder and its pathophysiology has puzzled clinicians for years. Few cases of POS are described in COVID-19 patients in the literature, with a high variability of conditions related to the syndrome. In this article, we report the case of a patient admitted to our hospital for SARS-CoV-2 interstitial pneumonia, who developed POS during the hospitalization.
    Learning points: Platypnoea-orthodeoxia syndrome (POS) is a possible and rare condition associated with SARS-CoV-2 pneumonia.A prompt diagnosis of POS is important in order to start careful and adequate oxygen supplementation.Clinical data on COVID-19 evolution in patients with POS and possible therapeutic and rehabilitative strategies are not available in the literature.
    Language English
    Publishing date 2021-10-22
    Publishing country Italy
    Document type Journal Article
    ISSN 2284-2594
    ISSN (online) 2284-2594
    DOI 10.12890/2021_002849
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Long-term impact of COVID-19 requiring elevated oxygen support and safety of prolonged positive pressure ventilation

    Francesca Salvotti / Riccardo Pellegrinelli / Veronica Geroldi / Francesca Leidi / Vittorio Scipione / Gigliola Flamminio / Antonella Pastori / Claudia Agabiti-Rosei / Carolina De Ciuceis / Damiano Rizzoni / Gianluca Edoardo Mario Boari

    Italian Journal of Medicine, Vol 17, Iss

    2023  Volume 3

    Abstract: In this study, we analyzed long-term sequelae in patients hospitalized at Montichiari Hospital (Brescia, Italy) during the COVID-19 acute phase, who needed a high-flow oxygen treatment. The follow-up evaluation has been performed after more than one year ...

    Abstract In this study, we analyzed long-term sequelae in patients hospitalized at Montichiari Hospital (Brescia, Italy) during the COVID-19 acute phase, who needed a high-flow oxygen treatment. The follow-up evaluation has been performed after more than one year from discharge through a quality-of-life phone interview, standard laboratory tests, chest computed tomography, and global spirometry with an evaluation of the diffusing capacity of the lungs for carbon monoxide (DLCO). In our analysis, we found that patients who needed high FiO2 support during the acute phase, independently from the device used to administer it, showed a long-term heavy burden of pulmonary consequences: more than half of patients presented radiological alterations and persistent dyspnea or DLCO alterations; about 17% of them had alterations compatible with pulmonary fibrosis. Further analysis included a comparison of long-term consequences in patients treated with different devices. An interesting result was that prolonged positive pressure ventilation treatment didn’t seem to cause persistent pulmonary damage and thus could be considered a safe approach. In conclusion, this study confirms the heavy quality-of-life impact of moderate to severe COVID-19 and highlights the importance of recognizing patients who will benefit from rehabilitative programs and customized follow-up depending on the acute phase disease severity.
    Keywords Long COVID ; follow-up ; high-oxygen support ; positive pressure ventilation ; Medicine ; R
    Subject code 610
    Language English
    Publishing date 2023-10-01T00:00:00Z
    Publisher PAGEPress Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Platypnoea-Orthodeoxia Syndrome in COVID-19

    Francesca Salvotti / Francesco Poiatti / Stefano Bressa / Giovanni Montani / Matteo Nardin / Damiano Rizzoni

    European Journal of Case Reports in Internal Medicine (2021)

    2021  

    Abstract: Platypnoea-orthodeoxia syndrome (POS) is a rare disorder and its pathophysiology has puzzled clinicians for years. Few cases of POS are described in COVID-19 patients in the literature, with a high variability of conditions related to the syndrome. In ... ...

    Abstract Platypnoea-orthodeoxia syndrome (POS) is a rare disorder and its pathophysiology has puzzled clinicians for years. Few cases of POS are described in COVID-19 patients in the literature, with a high variability of conditions related to the syndrome. In this article, we report the case of a patient admitted to our hospital for SARS-CoV-2 interstitial pneumonia, who developed POS during the hospitalization.
    Keywords platypnoea-orthodeoxia syndrome ; covid-19 ; sars-cov-2 ; Medicine ; R
    Language English
    Publishing date 2021-10-01T00:00:00Z
    Publisher SMC MEDIA SRL
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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