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  1. Article ; Online: Increasing utilization of contrast-enhanced ultrasound during abdominal biopsies: impact of an educational training program.

    Ho, Lisa M / Ronald, James / Wildman-Tobriner, Benjamin

    Journal of ultrasound

    2024  

    Abstract: Rational and objectives: To increase utilization of contrast-enhanced ultrasound (CEUS) during ultrasound-guided targeted liver biopsies.: Material and methods: Two educational training interventions performed to increase use of CEUS. First, 14 ... ...

    Abstract Rational and objectives: To increase utilization of contrast-enhanced ultrasound (CEUS) during ultrasound-guided targeted liver biopsies.
    Material and methods: Two educational training interventions performed to increase use of CEUS. First, 14 radiologists (fellowship-trained in Abdominal Imaging) given didactic teaching and case presentations on the use of CEUS. Second, hands-on teaching on how to use CEUS provided to the same group. To determine the efficacy of these two interventions, radiologists completed anonymous surveys to determine the level of understanding and acceptability of using CEUS before and 6 months after CEUS training. In addition, the percentage of CEUS assisted liver biopsies was compared for the 6 months before and 6 months after the training.
    Results: Pre-training survey completed by 11 radiologists and post-training survey completed by 9 radiologists. Before training, 11% survey responders use CEUS routinely, whereas 89% never or rarely used it. After training, 54% of respondents were new users and 100% reported they planned to use CEUS in the future. Unfamiliarity (71%) was the main reason for not using it. After training, 25% reported lack of comfort with using CEUS as the main reason for not using CEUS. During six months before training, CEUS was administered in 6% (10/172) of targeted liver biopsies. Six months after training, CEUS was used nearly twice as often (10%, 16/160, P = 0.09, 1-sided Boschloo test). The number of radiologists using CEUS increased to 57% (8/14) after training compared to 20% (3/14, P = 0.03, 1-sided Boschloo) before training.
    Conclusion: Educational training intervention increases use of CEUS during ultrasound-guided targeted liver biopsies.
    Language English
    Publishing date 2024-02-08
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2365426-0
    ISSN 1876-7931 ; 1971-3495
    ISSN (online) 1876-7931
    ISSN 1971-3495
    DOI 10.1007/s40477-023-00862-9
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  2. Article ; Online: Science communication with generative AI.

    Alvarez, Amanda / Caliskan, Aylin / Crockett, M J / Ho, Shirley S / Messeri, Lisa / West, Jevin

    Nature human behaviour

    2024  Volume 8, Issue 4, Page(s) 625–627

    MeSH term(s) Humans ; Artificial Intelligence ; Communication ; Science
    Language English
    Publishing date 2024-03-04
    Publishing country England
    Document type Journal Article
    ISSN 2397-3374
    ISSN (online) 2397-3374
    DOI 10.1038/s41562-024-01846-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Transgender Care Is Family Medicine: A Call to Action.

    Sullivan, Erika Anne / Stryker, Shanna D / Blaszczak, Julie / Spielvogel, Ryan / Ho, Tiffany / Kiraly, Bernadette / MacVane, Lisa / Nixon, Rachel / Sabb, Dylan M / Venkatesan, Anita / Rodríguez, José E

    Family medicine

    2024  Volume 56, Issue 4, Page(s) 229–233

    MeSH term(s) Humans ; Family Practice ; Transgender Persons ; Female ; Male
    Language English
    Publishing date 2024-05-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 639374-3
    ISSN 1938-3800 ; 0742-3225
    ISSN (online) 1938-3800
    ISSN 0742-3225
    DOI 10.22454/FamMed.2024.167363
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    Zs.A 2327: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Needle types used in abdominal cross-sectional interventional radiology: a survey of the Society of Abdominal Radiology emerging technology commission.

    Wildman-Tobriner, Benjamin / Ho, Lisa M / Bowman, Andrew W

    Abdominal radiology (New York)

    2021  Volume 47, Issue 8, Page(s) 2623–2631

    Abstract: Purpose: To identify commonly used needle types in cross-sectional interventional radiology (CSIR) and to review features and safety profiles of those needles.: Methods: Members of the Society of Abdominal Radiology (SAR) emerging technologies ... ...

    Abstract Purpose: To identify commonly used needle types in cross-sectional interventional radiology (CSIR) and to review features and safety profiles of those needles.
    Methods: Members of the Society of Abdominal Radiology (SAR) emerging technologies commission (ETC) on CSIR were sent a 13-question survey about what needles they use for common CSIR procedures: random and targeted solid organ biopsy, ultrasound-guided paracentesis, and ultrasound-guided thyroid fine needle aspiration (FNA). Results were compiled with descriptive statistics, and features of the most commonly used needles were reviewed.
    Results: 19 surveys were completed (response rate 57.6%, 19/33) from 16 institutions. For solid organ biopsies, the majority of respondents reported using an 18-gauge needle with an automatic firing mechanism and a variable throw length option. The most commonly used needle for both random and targeted biopsies was the Argon BioPince (26.3%, 5/19) The three most commonly used needles for solid organ biopsies all featured automatic firing, variable throw length options, and 18-gauge size. A 5 French Cook Yueh needle was most the most commonly used paracentesis needle (36.8%, 7/19). For thyroid FNA, all respondents used spinal needles, and 25-gauge was the most common size (72.2%, 13/18).
    Conclusion: Abdominal radiologists use a variety of needles when performing common interventional procedures. Members of the SAR CSIR ETC commonly use automatic, 18-gauge, variable throw length needles for solid organ biopsies, 5 French catheter style needles for paracentesis, and 25-gauge spinal needles for thyroid FNA.
    MeSH term(s) Biopsy, Fine-Needle ; Cross-Sectional Studies ; Equipment and Supplies ; Humans ; Pancreatic Neoplasms/pathology ; Paracentesis ; Radiology, Interventional ; Surveys and Questionnaires ; Technology
    Language English
    Publishing date 2021-06-14
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2839786-1
    ISSN 2366-0058 ; 2366-004X
    ISSN (online) 2366-0058
    ISSN 2366-004X
    DOI 10.1007/s00261-021-03145-1
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    Zs.A 1262: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  5. Article ; Online: Patient engagement with prescription refill text reminders across time and major societal events.

    Waughtal, Joy / Glorioso, Thomas J / Sandy, Lisa M / Peterson, Pamela N / Chavez, Catia / Bull, Sheana / Ho, P Michael / Allen, Larry A

    Cardiovascular digital health journal

    2023  Volume 4, Issue 4, Page(s) 133–136

    Language English
    Publishing date 2023-06-14
    Publishing country United States
    Document type Journal Article
    ISSN 2666-6936
    ISSN (online) 2666-6936
    DOI 10.1016/j.cvdhj.2023.06.002
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  6. Article ; Online: Low antibody levels associated with significantly increased rate of SARS-CoV-2 infection in a highly vaccinated population from the US National Basketball Association.

    Tai, Caroline G / Haviland, Miriam J / Kissler, Steven M / Lucia, Rachel M / Merson, Michael / Maragakis, Lisa L / Ho, David D / Anderson, Deverick J / DiFiori, John / Grubaugh, Nathan D / Grad, Yonatan H / Mack, Christina DeFilippo

    Journal of medical virology

    2024  Volume 96, Issue 3, Page(s) e29505

    Abstract: SARS-CoV-2 antibody levels may serve as a correlate for immunity and could inform optimal booster timing. The relationship between antibody levels and protection from infection was evaluated in vaccinated individuals from the US National Basketball ... ...

    Abstract SARS-CoV-2 antibody levels may serve as a correlate for immunity and could inform optimal booster timing. The relationship between antibody levels and protection from infection was evaluated in vaccinated individuals from the US National Basketball Association who had antibody levels measured at a single time point from September 12, 2021, to December 31, 2021. Cox proportional hazards models were used to estimate the risk of infection within 90 days of serologic testing by antibody level (<250, 250-800, and >800 AU/mL
    MeSH term(s) Humans ; Male ; Female ; COVID-19/prevention & control ; Basketball ; SARS-CoV-2 ; Antibodies, Viral ; Vaccines
    Chemical Substances Antibodies, Viral ; Vaccines
    Language English
    Publishing date 2024-03-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 752392-0
    ISSN 1096-9071 ; 0146-6615
    ISSN (online) 1096-9071
    ISSN 0146-6615
    DOI 10.1002/jmv.29505
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    Zs.A 1320: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  7. Journal ; Article ; Online: Establishing the impact of WHO’s normative and standard-setting functions

    Askie, Lisa M / Thomas, Rebekah AL / Kim, Rok Ho / Sheikh, Mubashar / Farrar, Jeremy

    a call for papers

    2023  

    Abstract: ... 618 ... ...

    Abstract 618

    618A
    Keywords Editorials
    Publishing date 2023-10-01
    Publisher World Health Organization
    Document type Journal ; Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Single-cell analysis of the CD8

    Favaloro, James / Bryant, Christian E / Abadir, Edward / Gardiner, Samuel / Yang, Shihong / King, Tracy / Nassif, Najah / Sedger, Lisa M / Boyle, Richard / Joshua, Douglas E / Ho, P Joy

    Haematologica

    2024  Volume 109, Issue 4, Page(s) 1220–1232

    Abstract: Multiple myeloma (MM) is an incurable disease of the bone marrow (BM) characterized by the uncontrolled proliferation of neoplastic plasma cells. While CD8+ T cells have an established role in disease control, few studies have focused on these cells ... ...

    Abstract Multiple myeloma (MM) is an incurable disease of the bone marrow (BM) characterized by the uncontrolled proliferation of neoplastic plasma cells. While CD8+ T cells have an established role in disease control, few studies have focused on these cells within the MM tumor microenvironment (TME). We analyzed CD8+ T cells in the BM and peripheral blood (PB) of untreated patients with MM and non-myeloma controls using flow cytometry, mass cytometry and single-cell RNA sequencing, using several novel bioinformatics workflows. Inter-tissue differences were most evident in the differential expression of Granzymes B and K, which were strongly associated with two distinct subsets of CD8+ T cells delineated by the expression of CD69, accounting for roughly 50% of BM-CD8+ T cells of all assessed cohorts. While few differences were observable between health and disease in the BM-restricted CD8CD69+ T-cell subset, the CD8+CD69- T-cell subset in the BM of untreated MM patients demonstrated increased representation of highly differentiated effector cells and evident compositional parallels between the PB, absent in age-matched controls, where a marked reduction of effector cells was observed. We demonstrate the transcriptional signature of BM-CD8+ T cells from patients with MM more closely resembles TCR-activated CD8+ T cells from age-matched controls than their resting counterparts.
    MeSH term(s) Humans ; Multiple Myeloma/pathology ; CD8-Positive T-Lymphocytes/metabolism ; T-Lymphocyte Subsets/pathology ; Bone Marrow/pathology ; Single-Cell Analysis ; Tumor Microenvironment
    Language English
    Publishing date 2024-04-01
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2333-4
    ISSN 1592-8721 ; 0017-6567 ; 0390-6078
    ISSN (online) 1592-8721
    ISSN 0017-6567 ; 0390-6078
    DOI 10.3324/haematol.2023.283062
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    Uh III Zs.76: Show issues Location:
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    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: Evaluation of available risk scores to predict multiple cardiovascular complications for patients with type 2 diabetes mellitus using electronic health records

    Joyce C Ho / Lisa R Staimez / K M Venkat Narayan / Lucila Ohno-Machado / Roy L Simpson / Vicki Stover Hertzberg

    Computer Methods and Programs in Biomedicine Update, Vol 3, Iss , Pp 100087- (2023)

    2023  

    Abstract: Aims: Various cardiovascular risk prediction models have been developed for patients with type 2 diabetes mellitus. Yet few models have been validated externally. We perform a comprehensive validation of existing risk models on a heterogeneous population ...

    Abstract Aims: Various cardiovascular risk prediction models have been developed for patients with type 2 diabetes mellitus. Yet few models have been validated externally. We perform a comprehensive validation of existing risk models on a heterogeneous population of patients with type 2 diabetes using secondary analysis of electronic health record data. Methods: Electronic health records of 47,988 patients with type 2 diabetes between 2013 and 2017 were used to validate 16 cardiovascular risk models, including 5 that had not been compared previously, to estimate the 1-year risk of various cardiovascular outcomes. Discrimination and calibration were assessed by the c-statistic and the Hosmer-Lemeshow goodness-of-fit statistic, respectively. Each model was also evaluated based on the missing measurement rate. Sub-analysis was performed to determine the impact of race on discrimination performance. Results: There was limited discrimination (c-statistics ranged from 0.51 to 0.67) across the cardiovascular risk models. Discrimination generally improved when the model was tailored towards the individual outcome. After recalibration of the models, the Hosmer-Lemeshow statistic yielded p-values above 0.05. However, several of the models with the best discrimination relied on measurements that were often imputed (up to 39% missing). Conclusion: No single prediction model achieved the best performance on a full range of cardiovascular endpoints. Moreover, several of the highest-scoring models relied on variables with high missingness frequencies such as HbA1c and cholesterol that necessitated data imputation and may not be as useful in practice. An open-source version of our developed Python package, cvdm, is available for comparisons using other data sources.
    Keywords Type 2 diabetes ; Cardiovascular disease ; Electronic health records ; Risk models ; Computer applications to medicine. Medical informatics ; R858-859.7
    Subject code 310
    Language English
    Publishing date 2023-01-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Toward individualized dosimetry for radiopharmaceutical therapy in day-to-day clinical practice of nuclear oncology: overcoming heterogeneity of radiation-absorbed dose to tumor and critical organs.

    Bodei, Lisa / Michael Tuttle, R / Grewal, Ravinder K / Mauguen, Audrey / Augensen, Finn / Abusamra, Murad / Mahajan, Sonia / Jayaprakasam, Vetri Sudar / Osborne, Joseph R / Haque, Sofia / Wong, Bernadette Z Y / Ghossein, Ronald A / Fagin, James / Schӧder, Heiko / Ho, Alan / Humm, John L / Larson, Steven M

    European journal of nuclear medicine and molecular imaging

    2023  Volume 51, Issue 2, Page(s) 325–329

    MeSH term(s) Humans ; Radiopharmaceuticals/therapeutic use ; Radiation Dosage ; Radiometry ; Neoplasms/radiotherapy ; Neoplasms/drug therapy
    Chemical Substances Radiopharmaceuticals
    Language English
    Publishing date 2023-09-15
    Publishing country Germany
    Document type Editorial
    ZDB-ID 8236-3
    ISSN 1619-7089 ; 0340-6997 ; 1619-7070
    ISSN (online) 1619-7089
    ISSN 0340-6997 ; 1619-7070
    DOI 10.1007/s00259-023-06420-z
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    Zs.A 1227: Show issues Location:
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