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  1. Article ; Online: Severe Acute Kidney Injury Associated with Giardia lamblia Infection.

    Ishikawa, Kazuhiro

    The American journal of tropical medicine and hygiene

    2023  Volume 109, Issue 1, Page(s) 4–5

    MeSH term(s) Humans ; Giardiasis/complications ; Giardia lamblia ; Diarrhea/complications ; Acute Kidney Injury
    Language English
    Publishing date 2023-05-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2942-7
    ISSN 1476-1645 ; 0002-9637
    ISSN (online) 1476-1645
    ISSN 0002-9637
    DOI 10.4269/ajtmh.23-0075
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  2. Article: Acute onset of hip pain and swelling with calcification mimicking pyogenic myositis.

    Ishikawa, Kazuhiro

    Clinical case reports

    2023  Volume 11, Issue 3, Page(s) e7142

    Abstract: In cases with acute hip pain, noninflammatory orthopedics diseases are common. But we sometimes experience acute pyomyositis with high inflammation. Although a rare case, we consider calcific tendonitis and pyogenic myositis. ...

    Abstract In cases with acute hip pain, noninflammatory orthopedics diseases are common. But we sometimes experience acute pyomyositis with high inflammation. Although a rare case, we consider calcific tendonitis and pyogenic myositis.
    Language English
    Publishing date 2023-03-24
    Publishing country England
    Document type Case Reports
    ZDB-ID 2740234-4
    ISSN 2050-0904
    ISSN 2050-0904
    DOI 10.1002/ccr3.7142
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  3. Article ; Online: Pyelonephritis with Anomaly of the Ureter and Calculi.

    Ishikawa, Kazuhiro

    Internal medicine (Tokyo, Japan)

    2023  Volume 62, Issue 23, Page(s) 3561–3562

    MeSH term(s) Humans ; Ureter/diagnostic imaging ; Ureter/abnormalities ; Pyelonephritis/diagnosis ; Pyelonephritis/diagnostic imaging ; Ureteral Obstruction ; Calculi ; Ureteral Calculi/complications ; Ureteral Calculi/diagnostic imaging
    Language English
    Publishing date 2023-04-14
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 32371-8
    ISSN 1349-7235 ; 0021-5120 ; 0918-2918
    ISSN (online) 1349-7235
    ISSN 0021-5120 ; 0918-2918
    DOI 10.2169/internalmedicine.1658-23
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  4. Article ; Online: A Randomized Controlled Trial of Preoperative Prophylactic Antibiotics for Percutaneous Nephrolithotomy in Moderate to High Infectious Risk Population: A Report From the EDGE Consortium. Letter.

    Ishikawa, Kazuhiro

    The Journal of urology

    2023  Volume 210, Issue 4, Page(s) 581

    MeSH term(s) Humans ; Nephrolithotomy, Percutaneous ; Anti-Bacterial Agents/therapeutic use ; Risk Factors ; Infections ; Kidney Calculi/surgery ; Nephrostomy, Percutaneous
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2023-07-26
    Publishing country United States
    Document type Randomized Controlled Trial ; Letter ; Comment
    ZDB-ID 3176-8
    ISSN 1527-3792 ; 0022-5347
    ISSN (online) 1527-3792
    ISSN 0022-5347
    DOI 10.1097/JU.0000000000003626
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  5. Article ; Online: Acute onset of hip pain and swelling with calcification mimicking pyogenic myositis

    Kazuhiro Ishikawa

    Clinical Case Reports, Vol 11, Iss 3, Pp n/a-n/a (2023)

    2023  

    Abstract: Abstract In cases with acute hip pain, noninflammatory orthopedics diseases are common. But we sometimes experience acute pyomyositis with high inflammation. Although a rare case, we consider calcific tendonitis and pyogenic myositis. ...

    Abstract Abstract In cases with acute hip pain, noninflammatory orthopedics diseases are common. But we sometimes experience acute pyomyositis with high inflammation. Although a rare case, we consider calcific tendonitis and pyogenic myositis.
    Keywords calcific tendonitis ; myositis of gluteus medius ; pyomyositis ; Medicine ; R ; Medicine (General) ; R5-920
    Language English
    Publishing date 2023-03-01T00:00:00Z
    Publisher Wiley
    Document type Article ; Online
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  6. Article ; Online: Corynebacterium

    Shimada, Tomohito / Ishikawa, Kazuhiro / Kawai, Fujimi / Mori, Nobuyoshi

    Leukemia & lymphoma

    2024  , Page(s) 1–6

    Abstract: ... ...

    Abstract Corynebacterium
    Language English
    Publishing date 2024-03-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1042374-6
    ISSN 1029-2403 ; 1042-8194
    ISSN (online) 1029-2403
    ISSN 1042-8194
    DOI 10.1080/10428194.2024.2331086
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  7. Article ; Online: Synthesis of causal and surrogate models by non-equilibrium thermodynamics in biological systems.

    Sakurada, Kazuhiro / Ishikawa, Tetsuo

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 1001

    Abstract: We developed a model to represent the time evolution phenomena of life through physics constraints. To do this, we took into account that living organisms are open systems that exchange messages through intracellular communication, intercellular ... ...

    Abstract We developed a model to represent the time evolution phenomena of life through physics constraints. To do this, we took into account that living organisms are open systems that exchange messages through intracellular communication, intercellular communication and sensory systems, and introduced the concept of a message force field. As a result, we showed that the maximum entropy generation principle is valid in time evolution. Then, in order to explain life phenomena based on this principle, we modelled the living system as a nonlinear oscillator coupled by a message and derived the governing equations. The governing equations consist of two laws: one states that the systems are synchronized when the variation of the natural frequencies between them is small or the coupling strength through the message is sufficiently large, and the other states that the synchronization is broken by the proliferation of biological systems. Next, to simulate the phenomena using data obtained from observations of the temporal evolution of life, we developed an inference model that combines physics constraints and a discrete surrogate model using category theory, and simulated the phenomenon of early embryogenesis using this inference model. The results show that symmetry creation and breaking based on message force fields can be widely used to model life phenomena.
    MeSH term(s) Thermodynamics ; Entropy ; Physics ; Causality ; Cell Communication
    Language English
    Publishing date 2024-01-10
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-51426-8
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  8. Article ; Online: Synthesis of causal and surrogate models by non-equilibrium thermodynamics in biological systems

    Kazuhiro Sakurada / Tetsuo Ishikawa

    Scientific Reports, Vol 14, Iss 1, Pp 1-

    2024  Volume 14

    Abstract: Abstract We developed a model to represent the time evolution phenomena of life through physics constraints. To do this, we took into account that living organisms are open systems that exchange messages through intracellular communication, intercellular ...

    Abstract Abstract We developed a model to represent the time evolution phenomena of life through physics constraints. To do this, we took into account that living organisms are open systems that exchange messages through intracellular communication, intercellular communication and sensory systems, and introduced the concept of a message force field. As a result, we showed that the maximum entropy generation principle is valid in time evolution. Then, in order to explain life phenomena based on this principle, we modelled the living system as a nonlinear oscillator coupled by a message and derived the governing equations. The governing equations consist of two laws: one states that the systems are synchronized when the variation of the natural frequencies between them is small or the coupling strength through the message is sufficiently large, and the other states that the synchronization is broken by the proliferation of biological systems. Next, to simulate the phenomena using data obtained from observations of the temporal evolution of life, we developed an inference model that combines physics constraints and a discrete surrogate model using category theory, and simulated the phenomenon of early embryogenesis using this inference model. The results show that symmetry creation and breaking based on message force fields can be widely used to model life phenomena.
    Keywords Medicine ; R ; Science ; Q
    Subject code 612
    Language English
    Publishing date 2024-01-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
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  9. Article ; Online: Bilateral Sialadenitis as an Uncommon Initial Manifestation of Infectious Mononucleosis: A Case Report.

    Ishiguro, Kenji / Ishikawa, Kazuhiro / Matsuo, Takahiro / Mori, Nobuyoshi

    Internal medicine (Tokyo, Japan)

    2024  

    Abstract: Sialadenitis has rarely been reported in patients with infectious mononucleosis (IM). Our patient was a 22-year-old man who presented with bilateral swelling of the parotid and submandibular glands, a fever, malaise, and splenomegaly. Laboratory tests ... ...

    Abstract Sialadenitis has rarely been reported in patients with infectious mononucleosis (IM). Our patient was a 22-year-old man who presented with bilateral swelling of the parotid and submandibular glands, a fever, malaise, and splenomegaly. Laboratory tests revealed an increased percentage of atypical lymphocytes in the leukocyte fraction. Serological testing for antibodies against Epstein-Barr virus (EBV) revealed an acute infection pattern. The patient was diagnosed with sialadenitis associated with IM caused by EBV infection. With symptomatic treatment, the salivary gland swelling completely resolved within a week. This case suggests that EBV-induced IM should be included in the differential diagnosis of diffuse sialadenitis with elevated atypical lymphocyte counts.
    Language English
    Publishing date 2024-04-09
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 32371-8
    ISSN 1349-7235 ; 0021-5120 ; 0918-2918
    ISSN (online) 1349-7235
    ISSN 0021-5120 ; 0918-2918
    DOI 10.2169/internalmedicine.2922-23
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  10. Article ; Online: Anaerobic gram-negative rod bacteremia as a marker of gastrointestinal cancer in Japanese patients: a single-center retrospective study.

    Abe, Eiko / Ishikawa, Kazuhiro / Onishi, Kazunari / Mori, Nobuyoshi

    Chinese clinical oncology

    2024  

    Abstract: Background: Gram-negative rod (GNR) bacteremia has been suggested as a clinical marker of occult cancer; however, no studies are available in this regard in the Japanese population. Here, we investigated the risk factors for gastrointestinal cancer with ...

    Abstract Background: Gram-negative rod (GNR) bacteremia has been suggested as a clinical marker of occult cancer; however, no studies are available in this regard in the Japanese population. Here, we investigated the risk factors for gastrointestinal cancer with GNR bacteremia.
    Methods: Patients with GNR bacteremia admitted to St. Luke's International Hospital between January 2011 and July 2021 were included. The clinical data of patients with and without cancer, 1 year before and after GNR bacteremia diagnosis, were compared. Univariate analysis was performed using χ2 and Fisher's exact tests for categorical variables and the Mann-Whitney U test for continuous variables, while multivariable analysis was performed using logistic regression analysis, and a P of <0.05 was considered statistically significant.
    Results: Of 2,296 GNR bacteremia-positive patients, 96 were associated with gastrointestinal cancer, and univariate analysis showed significant differences between the gastrointestinal cancer and comparison groups in terms of mean body mass index (BMI; 20.5 vs. 21.8 kg/m2 ), Enterobacterales detection (64.6% vs. 81.3%), and anaerobic GNR detection (24.0% vs. 8.5%). Thirty-five (36%) and 61 (64%) patients had upper and lower gastrointestinal cancer, respectively. There were 23 patients with anaerobic GNR bacteremia related to 24 strains (upper and lower gastrointestinal cancer, 5 and 18 cases, respectively). Multivariate analysis identified anaerobic GNR [odds ratio, 3.440; 95% confidence interval (CI): 2.085-5.675, P<0.001] as a significant risk factor for cancer.
    Conclusions: Anaerobic GNR in blood cultures may be a risk factor for gastrointestinal cancer. Therefore, it is necessary consider cancer workup, such as endoscopy, for patients with anaerobic GNR bacteremia.
    Language English
    Publishing date 2024-04-08
    Publishing country China
    Document type Journal Article
    ZDB-ID 2828547-5
    ISSN 2304-3873 ; 2304-3873
    ISSN (online) 2304-3873
    ISSN 2304-3873
    DOI 10.21037/cco-23-126
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