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  1. Article ; Online: Editorial of special focus on melanoma immunotherapy.

    Rossi, Ernesto

    Human vaccines & immunotherapeutics

    2022  Volume 18, Issue 3, Page(s) 2030170

    MeSH term(s) Humans ; Immunotherapy ; Melanoma/therapy
    Language English
    Publishing date 2022-05-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2664176-8
    ISSN 2164-554X ; 2164-5515
    ISSN (online) 2164-554X
    ISSN 2164-5515
    DOI 10.1080/21645515.2022.2030170
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  2. Article: Editorial: Non-cutaneous melanoma: new therapeutic insights.

    Rossi, Ernesto / Carvajal, Richard D

    Frontiers in oncology

    2024  Volume 13, Page(s) 1362238

    Language English
    Publishing date 2024-01-17
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2649216-7
    ISSN 2234-943X
    ISSN 2234-943X
    DOI 10.3389/fonc.2023.1362238
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  3. Article ; Online: Immunoterapia per melanoma metastatico con mutazione di BRAF.

    Rossi, Ernesto

    Recenti progressi in medicina

    2020  Volume 111, Issue 12, Page(s) 48e–53e

    Abstract: The treatment of cutaneous melanoma harboring BRAF mutation has been greatly enriched. BRAF/MEK inhibitors can improve the outcome of patients with this disease. On the other hand, immunotherapy can also be effective. A focus on the role of immune ... ...

    Title translation Immunotherapy for BRAF mutant metastatic melanoma.
    Abstract The treatment of cutaneous melanoma harboring BRAF mutation has been greatly enriched. BRAF/MEK inhibitors can improve the outcome of patients with this disease. On the other hand, immunotherapy can also be effective. A focus on the role of immune checkpoint inhibitors in advanced melanoma with BRAF mutation has been performed.
    MeSH term(s) Humans ; Immunologic Factors ; Immunotherapy ; Melanoma/genetics ; Melanoma/therapy ; Mutation ; Protein Kinase Inhibitors/therapeutic use ; Proto-Oncogene Proteins B-raf/genetics ; Skin Neoplasms/genetics ; Skin Neoplasms/therapy
    Chemical Substances Immunologic Factors ; Protein Kinase Inhibitors ; BRAF protein, human (EC 2.7.11.1) ; Proto-Oncogene Proteins B-raf (EC 2.7.11.1)
    Language Italian
    Publishing date 2020-12-27
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 138266-4
    ISSN 2038-1840 ; 0034-1193
    ISSN (online) 2038-1840
    ISSN 0034-1193
    DOI 10.1701/3509.34976
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  4. Article: Characterisation of Dry-Salted Violino and Bresaola from

    Lopez, Annalaura / Mainardi, Edda / Beretta, Ernesto / Ratti, Sabrina / Bellagamba, Federica / Corino, Carlo / Moretti, Vittorio Maria / Rossi, Raffaella

    Animals : an open access journal from MDPI

    2024  Volume 14, Issue 3

    Abstract: This study focuses on characterising two seasoned products, violino and bresaola, derived ... ...

    Abstract This study focuses on characterising two seasoned products, violino and bresaola, derived from
    Language English
    Publishing date 2024-02-01
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2606558-7
    ISSN 2076-2615
    ISSN 2076-2615
    DOI 10.3390/ani14030488
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  5. Article ; Online: Quality of life impact in patients with cutaneous toxicities caused by EGFR inhibitors and immunotherapy.

    Mannino, Maria / Sollena, Pietro / Di Stefani, Alessandro / Rossi, Ernesto / D'Argento, Ettore / Schinzari, Giovanni / Tortora, Giampaolo / Peris, Ketty

    Dermatology (Basel, Switzerland)

    2024  

    Abstract: Background: novel oncologic therapies, including epidermal growth factor receptor inhibitors (EGFR-Is) and immune checkpoint inhibitors (ICIs), are associated with a new spectrum of adverse reactions, with prominent cutaneous toxicities. The impact of ... ...

    Abstract Background: novel oncologic therapies, including epidermal growth factor receptor inhibitors (EGFR-Is) and immune checkpoint inhibitors (ICIs), are associated with a new spectrum of adverse reactions, with prominent cutaneous toxicities. The impact of cutaneous adverse events (cAEs) on patients' quality of life (QoL) represents an unmet clinical need.
    Objectives: 1) to assess whether cutaneous toxicities directed therapies are effective in reducing the QoL burden via the submission of two patient reported outcome measures (PROMs); 2) to investigate whether class of oncologic therapy, type of cAE and toxicity severity differently impact on patients' QoL.
    Methods: a prospective observational study was conducted at the Dermatology department of the Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy, from October 2018 to October 2019. Patients aged ≥ 18 years, under therapy with EGFR-Is or ICIs and experiencing a treatment-related cAE were eligible for the study. Dermatology Life Quality Index (DLQI) and European Organization for Research and Treatment of Cancer Quality of Life Questionnaire- Core 30 version 3.0 (EORTC QLQ-C30) were administered to patients at first clinical visit (T0), at 1-month (T1), and at 3-month (T2) dermatological follow-up.
    Results: Sixty cAEs of 51 patients have been recorded. A significant difference in the mean score for both DLQI and EORTC QLQ-C30 was found along the 3-months dermatological follow-up (p <0.0001). A similar QoL improvement was reported for PROMs stratified by class of therapy and toxicity severity (p <0.0001). No difference was reported for patients with pyogenic granuloma-like lesions and psoriasiform eruption as per DLQI. Class of therapy and toxicity severity did not differently impact on patients' QoL at selected timepoints; we reported a higher EORTC QLQ-C30 score at T2 for patients developing psoriasiform eruption compared to other types of cAEs.
    Conclusions: Early patients' referral to dermatologists and tailored management could result in better QoL.
    Language English
    Publishing date 2024-04-17
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1099692-8
    ISSN 1421-9832 ; 1018-8665
    ISSN (online) 1421-9832
    ISSN 1018-8665
    DOI 10.1159/000536332
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  6. Article ; Online: A Review of Significant European Foodborne Outbreaks in the Last Decade.

    Sarno, Eleonora / Pezzutto, Denise / Rossi, Mirko / Liebana, Ernesto / Rizzi, Valentina

    Journal of food protection

    2021  Volume 84, Issue 12, Page(s) 2059–2070

    MeSH term(s) Animals ; Disease Outbreaks ; Escherichia coli Infections/epidemiology ; Europe/epidemiology ; Foodborne Diseases/epidemiology ; Listeriosis ; Salmonella enteritidis ; Shiga-Toxigenic Escherichia coli
    Language English
    Publishing date 2021-06-27
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 243284-5
    ISSN 1944-9097 ; 0362-028X
    ISSN (online) 1944-9097
    ISSN 0362-028X
    DOI 10.4315/JFP-21-096
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  7. Article ; Online: Genius and joy: Ernest Lawrence Rossi.

    Rossi, Kathryn

    The American journal of clinical hypnosis

    2021  Volume 63, Issue 3, Page(s) 185–188

    Language English
    Publishing date 2021-02-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 219387-5
    ISSN 2160-0562 ; 0002-9157
    ISSN (online) 2160-0562
    ISSN 0002-9157
    DOI 10.1080/00029157.2020.1857153
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    Zs.A 420: Show issues Location:
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  8. Article: The Role of Postoperative Radiotherapy in the Management of Dermatofibrosarcoma Protuberans: A Multidisciplinary Systematic Review.

    Fionda, Bruno / Loperfido, Antonella / Di Stefani, Alessandro / Lancellotta, Valentina / Paradisi, Andrea / De Angeli, Martina / Cappilli, Simone / Rossi, Ernesto / Caretto, Anna Amelia / Zinicola, Tiziano / Schinzari, Giovanni / Gentileschi, Stefano / Morganti, Alessio Giuseppe / Rembielak, Agata / Peris, Ketty / Tagliaferri, Luca

    Journal of clinical medicine

    2024  Volume 13, Issue 6

    Abstract: ... ...

    Abstract Background
    Language English
    Publishing date 2024-03-21
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm13061798
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  9. Article ; Online: Radiomics to predict immunotherapy efficacy in advanced renal cell carcinoma: A retrospective study.

    Rossi, Ernesto / Boldrini, Luca / Maratta, Maria Grazia / Gatta, Roberto / Votta, Claudio / Tortora, Giampaolo / Schinzari, Giovanni

    Human vaccines & immunotherapeutics

    2023  Volume 19, Issue 1, Page(s) 2172926

    Abstract: Immunotherapy has become a cornerstone for the treatment of renal cell carcinoma. Nevertheless, some patients are resistant to immune checkpoint inhibitors. The possibility to identify patients who cannot benefit from immunotherapy is a relevant clinical ...

    Abstract Immunotherapy has become a cornerstone for the treatment of renal cell carcinoma. Nevertheless, some patients are resistant to immune checkpoint inhibitors. The possibility to identify patients who cannot benefit from immunotherapy is a relevant clinical challenge. We analyzed the association between several radiomics features and response to immunotherapy in 53 patients treated with checkpoint inhibitors for advanced renal cell carcinoma. We found that the following features are associated with progression of disease as best tumor response: F_stat.range (
    MeSH term(s) Humans ; Carcinoma, Renal Cell/diagnostic imaging ; Carcinoma, Renal Cell/therapy ; Retrospective Studies ; Antineoplastic Agents, Immunological/therapeutic use ; Immunotherapy/methods ; Kidney Neoplasms/diagnostic imaging ; Kidney Neoplasms/therapy ; Ipilimumab/therapeutic use
    Chemical Substances Antineoplastic Agents, Immunological ; Ipilimumab
    Language English
    Publishing date 2023-02-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2664176-8
    ISSN 2164-554X ; 2164-5515
    ISSN (online) 2164-554X
    ISSN 2164-5515
    DOI 10.1080/21645515.2023.2172926
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  10. Article ; Online: Pneumonitis from immune checkpoint inhibitors and COVID-19

    Giampaolo Tortora / Giovanni Schinzari / Ernesto Rossi

    Journal for ImmunoTherapy of Cancer, Vol 8, Iss

    current concern in cancer treatment

    2020  Volume 2

    Abstract: Pneumonitis is a rare but serious adverse event caused by cancer immunotherapy. The diagnosis between COVID-19-induced pneumonia and immunotherapy-induced pneumonitis may be challenging in the era of COVID-19 outbreak. Some clinical symptoms and ... ...

    Abstract Pneumonitis is a rare but serious adverse event caused by cancer immunotherapy. The diagnosis between COVID-19-induced pneumonia and immunotherapy-induced pneumonitis may be challenging in the era of COVID-19 outbreak. Some clinical symptoms and radiological findings of pneumonitis can be attributed to the coronavirus infection as well as to an immune-related adverse event. Identifying the exact cause of a pneumonitis in patients on treatment with immunotherapy is crucial to promptly start the most appropriate treatment. The proper management of immune checkpoint inhibitors for the risk of pneumonia must take into account a series of parameters. Accurate attention should be payed to symptoms like cough, fever and dyspnea during immunotherapy.
    Keywords Neoplasms. Tumors. Oncology. Including cancer and carcinogens ; RC254-282 ; covid19
    Language English
    Publishing date 2020-11-01T00:00:00Z
    Publisher BMJ Publishing Group
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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