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  1. Article: Mishra's Sign of Blunt Traumatic Pancreatic Injury': An Intra-Operative Telltale Sign Indicating Potential Blunt Traumatic Pancreatic Injury.

    Mishra, Biplab

    Bulletin of emergency and trauma

    2017  Volume 5, Issue 1, Page(s) 63–66

    Language English
    Publishing date 2017-01-26
    Publishing country Iran
    Document type Journal Article
    ZDB-ID 2722734-0
    ISSN 2322-3960 ; 2322-2522
    ISSN (online) 2322-3960
    ISSN 2322-2522
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Mishra’s Sign of Blunt Traumatic Pancreatic Injury’

    Biplab Mishra

    Bulletin of Emergency And Trauma, Vol 5, Iss 1, Pp 63-

    An Intra-Operative Telltale Sign Indicating Potential Blunt Traumatic Pancreatic Injury

    2017  Volume 66

    Keywords Blunt trauma pancreas ; Pancreatic transection ; Traumatic MPD injury ; Intra-operative sign ; Mishra’s sign ; Surgery ; RD1-811 ; Medicine ; R
    Language English
    Publishing date 2017-01-01T00:00:00Z
    Publisher Shiraz University of Medical Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Corrigendum to "Prognostic value of circulating mitochondrial DNA in prostate cancer and underlying mechanism" [Mitochondrion 71 (2023) 40-49].

    Borah, Supriya / Mishra, Rajeev / Dey, Sananda / Suchanti, Surabhi / Bhowmick, Neil A / Giri, Biplab / Haldar, Subhash

    Mitochondrion

    2023  Volume 71, Page(s) 63

    Language English
    Publishing date 2023-06-03
    Publishing country Netherlands
    Document type Published Erratum
    ZDB-ID 2056923-3
    ISSN 1872-8278 ; 1567-7249
    ISSN (online) 1872-8278
    ISSN 1567-7249
    DOI 10.1016/j.mito.2023.05.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Rhodium(III)-Catalyzed C–H Activation in Indole: A Comprehensive Report (2017–2022)

    Gope, Biplab / Mishra, Anupam / Awasthi, Satish K.

    Synthesis

    2023  

    Abstract: In the realm of synthetic organic chemistry, the catalysis of directed C–H activation by transition metals is an outstanding and efficient method for the synthesis of natural products, organic materials, and fundamental organic building blocks. Notably, ... ...

    Abstract In the realm of synthetic organic chemistry, the catalysis of directed C–H activation by transition metals is an outstanding and efficient method for the synthesis of natural products, organic materials, and fundamental organic building blocks. Notably, this strategy has experienced remarkable advances in recent years, particularly in its application to various substrate classes, including the essential indole scaffold. Indole is a highly sought-after target in organic chemistry. The significance of indole extends beyond its use in total synthesis and drug discovery. It also serves as an important tool in the development of pharmaceutical agents, agrochemicals, and materials. By targeting indole, synthetic chemists can access a wide range of bioactive compounds, which opens new avenues for drug development and chemical biology research. The synthesis of structurally varied indoles has been greatly aided by the development of a comprehensive toolkit made possible by the use of C–H activation as a versatile functionalization platform. This review highlights the latest breakthroughs in rhodium-catalyzed C–H activation at the C2, C4, and C7 positions of the indole scaffold. These developments represent significant progress in the field and hold promising potential for further advances in the synthesis of indole-based compounds. 1

    Introduction 2

    The Development of Rhodium-Catalyzed C–H Activation 3

    General Mechanistic Introduction to Rh(III)-Catalyzed C–H Activation 4

    Direct C–H Functionalization of Indoles 4.1

    C2 Activation of Indoles 4.2

    C4 Activation of Indoles 4.3

    Dual C–H Activation Strategy 4.4

    C7 Activation of Indoles 5

    Conclusion
    Keywords indole ; rhodium catalysis ; C–H activation ; directed C–H functionalization ; annulation ; hydroarylation ; C–H dienylation
    Language English
    Publishing date 2023-11-06
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2033062-5
    ISSN 1437-210X ; 0039-7881
    ISSN (online) 1437-210X
    ISSN 0039-7881
    DOI 10.1055/s-0042-1751497
    Database Thieme publisher's database

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  5. Article: Avoidance of 'Mishra Phenomenon' Prevents Technical Failure of Hepatic Artery Angioembolization following Failed Perihepatic Packing in Traumatic Liver Injury.

    Mishra, Biplab / Joshi, Mohit

    Bulletin of emergency and trauma

    2017  Volume 5, Issue 2, Page(s) 135–139

    Language English
    Publishing date 2017-05-01
    Publishing country Iran
    Document type Journal Article
    ZDB-ID 2722734-0
    ISSN 2322-3960 ; 2322-2522
    ISSN (online) 2322-3960
    ISSN 2322-2522
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Prognostic value of circulating mitochondrial DNA in prostate cancer and underlying mechanism.

    Borah, Supriya / Mishra, Rajeev / Dey, Sananda / Suchanti, Surabhi / Bhowmick, Neil A / Giri, Biplab / Haldar, Subhash

    Mitochondrion

    2023  Volume 71, Page(s) 40–49

    Abstract: Circulating DNAs are considered as degraded DNA fragments of approximately 50-200 bp, found in blood plasma, consisting of cell-free mitochondrial and nuclear DNA. Such cell-free DNAs in the blood are found to be altered in different pathological ... ...

    Abstract Circulating DNAs are considered as degraded DNA fragments of approximately 50-200 bp, found in blood plasma, consisting of cell-free mitochondrial and nuclear DNA. Such cell-free DNAs in the blood are found to be altered in different pathological conditions including lupus, heart disease, and malignancies. While nuclear DNAs are being used and being developed as a powerful clinical biomarker in liquid biopsies, mitochondrial DNAs (mtDNAs) are associated with inflammatory conditions including cancer progression. Patients with cancer including prostate cancer are found to have measurable concentrations of mitochondrial DNA in circulation in comparison with healthy controls. The plasma content of mitochondrial DNA is dramatically elevated in both prostate cancer patients and mouse models treated with the chemotherapeutic drug. Cell-free mtDNA, in its oxidized form, induced a pro-inflammatory condition and activates NLRP3-mediated inflammasome formation which causes IL-1β-mediated activation of growth factors. On the other hand, interacting with TLR9, mtDNAs trigger NF-κB-mediated complement C3a positive feedback paracrine loop and activate pro-proliferating signaling through upregulating AKT, ERK, and Bcl2 in the prostate tumor microenvironment. In this review, we discuss the growing evidence supporting cell-free mitochondrial DNA copy number, size, and mutations in mtDNA genes as potential prognostic biomarkers in different cancers and targetable prostate cancer therapeutic candidates impacting stromal-epithelial interactions essential for chemotherapy response.
    MeSH term(s) Humans ; Male ; Animals ; Mice ; DNA, Mitochondrial/metabolism ; Cell-Free Nucleic Acids ; Prognosis ; Prostatic Neoplasms/genetics ; Prostatic Neoplasms/pathology ; Mitochondria/metabolism ; Tumor Microenvironment
    Chemical Substances DNA, Mitochondrial ; Cell-Free Nucleic Acids
    Language English
    Publishing date 2023-05-19
    Publishing country Netherlands
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2056923-3
    ISSN 1872-8278 ; 1567-7249
    ISSN (online) 1872-8278
    ISSN 1567-7249
    DOI 10.1016/j.mito.2023.05.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Serum Zinc Level and Efficacy of Zinc Therapy in Cutaneous Leishmaniasis: a Systematic Review and Meta-analysis.

    Pal, Biplab / Mishra, Ashish Kumar / Raj, Harsh / Chaudhary, Vaibhav / Khurana, Navneet / Azharuddin, Mohammad / Kumari, Sweta

    Biological trace element research

    2023  Volume 202, Issue 5, Page(s) 1856–1865

    Abstract: Cutaneous leishmaniasis is a parasitic skin disease prevalent in many parts of the world. Zinc has been investigated for its potential role in the immune response against Leishmania parasites. This study aimed to systematically review the literature and ... ...

    Abstract Cutaneous leishmaniasis is a parasitic skin disease prevalent in many parts of the world. Zinc has been investigated for its potential role in the immune response against Leishmania parasites. This study aimed to systematically review the literature and conduct meta-analyses to evaluate the serum zinc level and efficacy of zinc therapy in cutaneous leishmaniasis. A comprehensive search of electronic databases was performed to find studies reporting serum zinc levels and the efficacy of zinc therapy in cutaneous leishmaniasis. Meta-analyses were conducted using RevMan software (version 5.4), calculating the mean difference for serum zinc levels and risk ratio for the efficacy of zinc therapy. A total of 11 studies with 1009 participants were evaluated. Five of these studies, comprising 637 participants, examined serum zinc levels; the remaining six, involving 372 individuals, examined the effectiveness of zinc therapy in treating cutaneous leishmaniasis. The results showed that the serum zinc level was significantly lower in cutaneous leishmaniasis patients compared to controls (MD: - 26.65; 95% CI: [- 42.74, - 10.57]; p = 0.001). However, zinc therapy did not demonstrate a significant clinical improvement compared to standard treatment (RR: 0.96; 95% CI: [0.74, 1.23], p = 0.73).
    MeSH term(s) Humans ; Zinc/therapeutic use ; Leishmaniasis, Cutaneous/drug therapy
    Chemical Substances Zinc (J41CSQ7QDS)
    Language English
    Publishing date 2023-08-03
    Publishing country United States
    Document type Meta-Analysis ; Systematic Review ; Journal Article ; Review
    ZDB-ID 445336-0
    ISSN 1559-0720 ; 0163-4984
    ISSN (online) 1559-0720
    ISSN 0163-4984
    DOI 10.1007/s12011-023-03797-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 2323: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
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  8. Article ; Online: Avoidance of ‘Mishra Phenomenon’ Prevents Technical Failure of Hepatic Artery Angioembolization following Failed Perihepatic Packing in Traumatic Liver Injury

    Biplab Mishra / Mohit Joshi

    Bulletin of Emergency And Trauma, Vol 5, Iss 2, Pp 135-

    2017  Volume 139

    Keywords Hepatic artery angiography ; Hepatic artery angioembolization ; Perihepatic packing ; Traumatic liver injury ; Mishra phenomenon ; Surgery ; RD1-811 ; Medicine ; R
    Language English
    Publishing date 2017-04-01T00:00:00Z
    Publisher Shiraz University of Medical Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article: IrO2 modified Crystalline-PdO nanowires based bi-functional electro-catalyst for HOR/HER in acid and base

    Samanta, Rajib / Mishra, Ranjit / Manna, Biplab Kumar / Barman, Sudip

    Renewable energy. 2022 May, v. 191

    2022  

    Abstract: Development of active HOR/HER electro-catalyst is crucial for development of next-generation PEM-and-AEM based renewable technologies. Here, IrO₂-modified PdO-nanostructures/carbon-composite with plenty of surface defects was synthesized for HER/HOR ... ...

    Abstract Development of active HOR/HER electro-catalyst is crucial for development of next-generation PEM-and-AEM based renewable technologies. Here, IrO₂-modified PdO-nanostructures/carbon-composite with plenty of surface defects was synthesized for HER/HOR applications. The ECSA of IrO₂–PdO/C is found to be 449 m g⁻¹ which is ∼9-fold higher than Pt/C in acid. The HER of IrO₂–PdO/C are 1.15-and 2.35-fold higher than Pt/C in acid and base. The stability test shows excellent stability of this catalyst. It also shows superior HOR activity. The i₀,ₘ of IrO₂–PdO/C is ∼647 and 376 mA/mgₘₑₜₐₗ in acid and base that are 1.78-and 3.63-times higher in compared to commercial Pt/C. Small amount of IrO₂ in IrO₂–PdO/C enhances its HOR/HER activity ∼300 times as compared to PdO/C. The IrO₂ or defects of the catalyst absorb OHₐd that reacts with neighboring Hₐd at defect sites or interfaces leading to increase HER/HOR performance through bifunctional mechanism. We demonstrate volcano relationship between exchange current and H∗/OH∗ binding energy confirming that HBE and OHBE are equal descriptors for HOR/HER in base. The HOR/HER in different electrolyte and increasing Li⁺ ions suggests [(H₂O)ₓ-M⁺-OHₐd ] in double layer influences the HOR/HER in base. This work could lead to the development of Pt-free electrocatalysts for renewable energy technologies.
    Keywords catalysts ; energy ; nanowires ; renewable energy sources
    Language English
    Dates of publication 2022-05
    Size p. 151-160.
    Publishing place Elsevier Ltd
    Document type Article
    ZDB-ID 2001449-1
    ISSN 1879-0682 ; 0960-1481
    ISSN (online) 1879-0682
    ISSN 0960-1481
    DOI 10.1016/j.renene.2022.04.028
    Database NAL-Catalogue (AGRICOLA)

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  10. Article ; Online: Role of Flavonoids in Neurodegenerative Diseases: Limitations and Future Perspectives.

    Maan, Gagandeep / Sikdar, Biplab / Kumar, Ashish / Shukla, Rahul / Mishra, Awanish

    Current topics in medicinal chemistry

    2020  Volume 20, Issue 13, Page(s) 1169–1194

    Abstract: Background: Flavonoids, a group of natural dietary polyphenols, are known for their beneficial effects on human health. By virtue of their various pharmacological effects, like anti-oxidative, antiinflammatory, anti-carcinogenic and neuroprotective ... ...

    Abstract Background: Flavonoids, a group of natural dietary polyphenols, are known for their beneficial effects on human health. By virtue of their various pharmacological effects, like anti-oxidative, antiinflammatory, anti-carcinogenic and neuroprotective effects, flavonoids have now become an important component of herbal supplements, pharmaceuticals, medicinals and cosmetics. There has been enormous literature supporting neuroprotective effect of flavonoids. Recently their efficacy in various neurodegenerative diseases, like Alzheimer's disease and Parkinson diseases, has received particular attention.
    Objective: The mechanism of flavanoids neuroprotection might include antioxidant, antiapoptotic, antineuroinflammatory and modulation of various cellular and intracellular targets. In in-vivo systems, before reaching to brain, they have to cross barriers like extensive first pass metabolism, intestinal barrier and ultimately blood brain barrier. Different flavonoids have varied pharmacokinetic characteristics, which affect their pharmacodynamic profile. Therefore, brain accessibility of flavonoids is still debatable.
    Methods: This review emphasized on current trends of research and development on flavonoids, especially in neurodegenerative diseases, possible challenges and strategies to encounter using novel drug delivery system.
    Results: Various flavonoids have elicited their therapeutic potential against neurodegenerative diseases, however by using nanotechnology and novel drug delivery systems, the bioavailability of favonoids could be enhanced.
    Conclusion: This study bridges a significant opinion on medicinal chemistry, ethanopharmacology and new drug delivery research regarding use of flavonoids in management of neurodegeneration.
    MeSH term(s) Drug Delivery Systems ; Flavonoids/chemistry ; Flavonoids/therapeutic use ; Humans ; Neurodegenerative Diseases/drug therapy ; Neurodegenerative Diseases/metabolism ; Neuroprotective Agents/chemistry ; Neuroprotective Agents/therapeutic use
    Chemical Substances Flavonoids ; Neuroprotective Agents
    Language English
    Publishing date 2020-04-30
    Publishing country United Arab Emirates
    Document type Journal Article ; Review
    ZDB-ID 2064823-6
    ISSN 1873-4294 ; 1568-0266
    ISSN (online) 1873-4294
    ISSN 1568-0266
    DOI 10.2174/1568026620666200416085330
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5572: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
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