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  1. Article ; Online: Cyclooxygenase-2 Selective Nonsteroidal Anti-Inflammatory Drugs in the Chronic Kidney Disease Population: Are They Rational or Reckless?

    Karri, Jay / D'Souza, Ryan S / Wang, Eric J

    Anesthesia and analgesia

    2024  

    Language English
    Publishing date 2024-02-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80032-6
    ISSN 1526-7598 ; 0003-2999
    ISSN (online) 1526-7598
    ISSN 0003-2999
    DOI 10.1213/ANE.0000000000006574
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: A Response to: Letter to the Editor Regarding Radiofrequency Treatment-Newer Modes and Long-Term Effects.

    Abd-Elsayed, Alaa / Karri, Jay

    Pain and therapy

    2021  Volume 10, Issue 2, Page(s) 1777–1778

    Language English
    Publishing date 2021-07-03
    Publishing country New Zealand
    Document type Letter
    ZDB-ID 2701614-6
    ISSN 2193-651X ; 2193-8237
    ISSN (online) 2193-651X
    ISSN 2193-8237
    DOI 10.1007/s40122-021-00285-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Editorial: Translational research in neuropathic pain: Current status and future directions.

    Karri, Jay / Nagpal, Ameet S / Li, Sheng

    Frontiers in pain research (Lausanne, Switzerland)

    2022  Volume 3, Page(s) 1024013

    Language English
    Publishing date 2022-09-09
    Publishing country Switzerland
    Document type Editorial
    ISSN 2673-561X
    ISSN (online) 2673-561X
    DOI 10.3389/fpain.2022.1024013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Methodological and statistical characteristics of meta-analyses on spinal cord stimulation for chronic pain: a systematic review.

    Kleppel, Donald J / Copeland, Royce / Hussain, Nasir / Karri, Jay / Wang, Eric / D'Souza, Ryan S

    Regional anesthesia and pain medicine

    2024  

    Abstract: Background: A growing number of meta-analyses (MA) have investigated the use of spinal cord stimulation (SCS) as a treatment modality for chronic pain. The quality of these MAs has not been assessed by validated appraisal tools.: Objective: To ... ...

    Abstract Background: A growing number of meta-analyses (MA) have investigated the use of spinal cord stimulation (SCS) as a treatment modality for chronic pain. The quality of these MAs has not been assessed by validated appraisal tools.
    Objective: To examine the methodological characteristics and quality of MAs related to the use of SCS for chronic pain syndromes.
    Evidence review: An online literature search was conducted in Ovid MEDLINE(R), Ovid EMBASE, Ovid Cochrane Database of Systematic Reviews, and Scopus databases (January 1, 2000 through June 30, 2023) to identify MAs that investigated changes in pain intensity, opioid consumption, and/or physical function after SCS for the treatment of chronic pain. MA quality was assessed using A Measurement Tool to Assess Systematic Reviews (AMSTAR-2) critical appraisal tool.
    Findings: Twenty-five MAs were appraised in the final analysis. Three were considered "high" quality, three "low" quality, and 19 "critically low" quality, per the AMSTAR-2 criteria. There was no association between the publication year and AMSTAR-2 overall quality (β 0.043; 95% CI -0.008 to 0.095; p=0.097). There was an association between the impact factor and AMSTAR-2 overall quality (β 0.108; 95% CI 0.044 to 0.172; p=0.002), such that studies published in journals with higher impact factors were associated with higher overall quality. There was no association between the effect size and AMSTAR-2 overall quality (β -0.168; 95% CI -0.518 to 0.183; p=0.320).According to our power analysis, three studies were adequately powered (>80%) to reject the null hypothesis, while the remaining studies were underpowered (<80%).
    Conclusions: The study demonstrates a critically low AMSTAR-2 quality for most MAs published on the use of SCS for treating chronic pain. Future MAs should improve study quality by implementing the AMSTAR-2 checklist items.
    Prospero registration number: CRD42023431155.
    Language English
    Publishing date 2024-02-21
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1425299-5
    ISSN 1532-8651 ; 1098-7339 ; 0146-521X
    ISSN (online) 1532-8651
    ISSN 1098-7339 ; 0146-521X
    DOI 10.1136/rapm-2023-105249
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Dorsal Root Ganglion Stimulation for Post-Lyme Disease Chronic Peripheral Neuropathic Pain.

    Karri, Jay / Bruel, Brian

    Neuromodulation : journal of the International Neuromodulation Society

    2020  Volume 24, Issue 4, Page(s) 794–795

    MeSH term(s) Chronic Pain ; Ganglia, Spinal ; Humans ; Lyme Disease ; Neuralgia/etiology ; Neuralgia/therapy ; Spinal Cord Stimulation
    Language English
    Publishing date 2020-03-08
    Publishing country United States
    Document type Letter
    ZDB-ID 1500372-3
    ISSN 1525-1403 ; 1094-7159
    ISSN (online) 1525-1403
    ISSN 1094-7159
    DOI 10.1111/ner.13136
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Antimicrobial therapies for chronic pain (part 1): analgesic mechanisms.

    Wang, Eric J / Karri, Jay / Tontisirin, Nuj / Cohen, Steven P

    The Korean journal of pain

    2023  Volume 36, Issue 3, Page(s) 281–298

    Abstract: There is increasing evidence that the relationship between chronic pain and infections is complex and intertwined. Bacterial and viral infections can cause pain through numerous mechanisms such as direct tissue damage and inflammation, the induction of ... ...

    Abstract There is increasing evidence that the relationship between chronic pain and infections is complex and intertwined. Bacterial and viral infections can cause pain through numerous mechanisms such as direct tissue damage and inflammation, the induction of excessive immunologic activity, and the development of peripheral or central sensitization. Treating infections might relieve pain by attenuating these processes, but a growing body of literature suggests that some antimicrobial therapies confer analgesic effects, including for nociceptive and neuropathic pain symptoms, and affective components of pain. The analgesic mechanisms of antimicrobials are indirect, but might be conceptualized into two broad categories: 1) the reduction of the infectious burden and associated pro-inflammatory processes; and 2) the inhibition of signaling processes (e.g., enzymatic and cytokine activity) necessary for nociception and maladaptive neuroplastic changes via off-target effects (unintended binding sites). For the former, there is evidence that symptoms of chronic low back pain (when associated with Modic type 1 changes), irritable bowel syndrome, inflammatory bowel disease, chronic pelvic pain, and functional dyspepsia might be improved after antibiotic treatment, though significant questions remain regarding specific regimens and dose, and which subpopulations are most likely to benefit. For the latter, there is evidence that several antimicrobial classes and medications exert analgesic effects independent of their reduction of infectious burden, and these include cephalosporins, ribavirin, chloroquine derivatives, rapalogues, minocycline, dapsone, and piscidin-1. This article aims to comprehensively review the existing literature for antimicrobial agents that have demonstrated analgesic efficacy in preclinical or clinical studies.
    Language English
    Publishing date 2023-07-03
    Publishing country Korea (South)
    Document type Journal Article ; Review
    ZDB-ID 2558899-0
    ISSN 2093-0569 ; 2005-9159
    ISSN (online) 2093-0569
    ISSN 2005-9159
    DOI 10.3344/kjp.23129
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Utility of Substandard Face Mask Options for Health Care Workers During the COVID-19 Pandemic.

    Abd-Elsayed, Alaa / Karri, Jay

    Anesthesia and analgesia

    2020  Volume 131, Issue 1, Page(s) 4–6

    MeSH term(s) COVID-19 ; Coronavirus Infections/prevention & control ; Coronavirus Infections/transmission ; Filtration ; Health Personnel ; Humans ; Masks/standards ; Pandemics/prevention & control ; Pneumonia, Viral/prevention & control ; Pneumonia, Viral/transmission ; Ventilators, Mechanical
    Keywords covid19
    Language English
    Publishing date 2020-04-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80032-6
    ISSN 1526-7598 ; 0003-2999
    ISSN (online) 1526-7598
    ISSN 0003-2999
    DOI 10.1213/ANE.0000000000004841
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Antimicrobial therapies for chronic pain (part 2): the prevention and treatment of chronic pain.

    Wang, Eric J / Dolomisiewicz, Edward / Karri, Jay / Tontisirin, Nuj / Cohen, Steven P

    The Korean journal of pain

    2023  Volume 36, Issue 3, Page(s) 299–315

    Abstract: The discovery and development of antimicrobial therapies represents one of the most significant advancements in modern medicine. Although the primary therapeutic intent of antimicrobials is to eliminate their target pathogens, several antimicrobials have ...

    Abstract The discovery and development of antimicrobial therapies represents one of the most significant advancements in modern medicine. Although the primary therapeutic intent of antimicrobials is to eliminate their target pathogens, several antimicrobials have been shown to provide analgesia as a secondary benefit. Antimicrobials have demonstrated analgesic effects in conditions that involve dysbiosis or potential subclinical infection (
    Language English
    Publishing date 2023-07-03
    Publishing country Korea (South)
    Document type Journal Article ; Review
    ZDB-ID 2558899-0
    ISSN 2093-0569 ; 2005-9159
    ISSN (online) 2093-0569
    ISSN 2005-9159
    DOI 10.3344/kjp.23130
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Perioperative and anesthetic considerations for the management of neuromodulation systems.

    Orhurhu, Vwaire / Hussain, Nasir / Karri, Jay / Mariano, Edward R / Abd-Elsayed, Alaa

    Regional anesthesia and pain medicine

    2023  Volume 48, Issue 6, Page(s) 327–336

    Abstract: The use of neuromodulation systems is increasing for the treatment of various pathologies ranging from movement disorders to urinary incontinence to chronic pain syndromes. While the type of neuromodulation devices varies, they are largely categorized as ...

    Abstract The use of neuromodulation systems is increasing for the treatment of various pathologies ranging from movement disorders to urinary incontinence to chronic pain syndromes. While the type of neuromodulation devices varies, they are largely categorized as intracranial (eg, deep brain stimulation), neuraxial (eg, spinal cord stimulation, dorsal root ganglion stimulation, and intrathecal drug delivery systems), or peripheral (eg, sacral nerve stimulation and peripheral nerve stimulation) systems. Given the increasing prevalence of these systems in the overall population, it is important for anesthesiologists, surgeons, and the perioperative healthcare team to familiarize themselves with these systems and their unique perioperative considerations. In this review, we explore and highlight the various neuromodulation systems, their general perioperative considerations, and notable special circumstances for perioperative management.
    MeSH term(s) Humans ; Transcutaneous Electric Nerve Stimulation ; Spinal Cord Stimulation ; Chronic Pain/diagnosis ; Chronic Pain/therapy ; Spinal Nerves ; Anesthetics
    Chemical Substances Anesthetics
    Language English
    Publishing date 2023-04-20
    Publishing country England
    Document type Review ; Journal Article
    ZDB-ID 1425299-5
    ISSN 1532-8651 ; 1098-7339 ; 0146-521X
    ISSN (online) 1532-8651
    ISSN 1098-7339 ; 0146-521X
    DOI 10.1136/rapm-2022-103660
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 2399: Show issues Location:
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  10. Article ; Online: The Use of Scrambler Therapy in Treating Chronic Pain Syndromes: A Systematic Review.

    Karri, Jay / Marathe, Anuj / Smith, Thomas J / Wang, Eric J

    Neuromodulation : journal of the International Neuromodulation Society

    2022  Volume 26, Issue 8, Page(s) 1499–1509

    Abstract: Background: Scrambler therapy (ST) is a noninvasive method of transcutaneous neuromodulation that has 510(K) clearance from the United States Food and Drug Administration for treating acute pain, postoperative pain, and intractable chronic pain. Since ... ...

    Abstract Background: Scrambler therapy (ST) is a noninvasive method of transcutaneous neuromodulation that has 510(K) clearance from the United States Food and Drug Administration for treating acute pain, postoperative pain, and intractable chronic pain. Since its inception, ST has been used to treat many chronic pain syndromes in a variety of patient populations. We synthesized the available literature for ST to delineate its overall evidence basis.
    Materials and methods: We performed a systematic review based on conventional Preferred Reporting Items for Systematic Reviews and Meta-Analyses methods by surveying multiple data sources from January 1950 through October 2021. Two review authors, independently and in a standardized, unblinded fashion, conducted a systematic review to identify relevant studies and extract the necessary outcome measures. A conservative search strategy was implemented to identify all ST studies for the treatment of chronic pain syndromes. Primary outcome parameters collected were analgesic benefit, adverse effects, and other metrics such as sensorimotor testing.
    Results: A total of 21 studies met the final criteria for study inclusion and comprised randomized controlled trials (n = 8), prospective observational studies (n = 10), and retrospective cohort studies (n = 3). Nearly all the reported studies explored the use of ST for the treatment of neuropathic pain, with chemotherapy-induced peripheral neuropathy being the most studied condition. Most studies were limited by small cohorts but reported ST being safe, well tolerated, and providing clinically meaningful pain reduction. The duration of posttreatment follow-up ranged from ten to 14 days (concordant with completion of typical ST protocols) to three months. Secondary benefits such as medication reduction and improvement of sensory and motor symptoms were noted by some studies.
    Conclusions: ST is regarded as a safe intervention with potential for significant analgesic benefit for neuropathic pain conditions. Although the available evidence is most robust for treating chemotherapy-induced peripheral neuropathy, ST has also been shown to be effective in treating other neuropathic pain syndromes. Evidence for ST use in nociceptive pain conditions is limited but appears promising. The favorable safety profile and increasing evidence basis for ST warrant more extensive recognition and consideration for use in clinical care.
    MeSH term(s) Humans ; Chronic Pain/drug therapy ; Retrospective Studies ; Analgesics/therapeutic use ; Neuralgia/therapy ; Antineoplastic Agents ; Randomized Controlled Trials as Topic ; Observational Studies as Topic
    Chemical Substances Analgesics ; Antineoplastic Agents
    Language English
    Publishing date 2022-06-09
    Publishing country United States
    Document type Systematic Review ; Journal Article ; Review
    ZDB-ID 1500372-3
    ISSN 1525-1403 ; 1094-7159
    ISSN (online) 1525-1403
    ISSN 1094-7159
    DOI 10.1016/j.neurom.2022.04.045
    Database MEDical Literature Analysis and Retrieval System OnLINE

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