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Article ; Online: Características Agroclimática de la E. C. V. "V.I. Lenin" de Matanzas y potencial en la actividad agroecológica.

Aida C. Ochoa Perdomo / María Eugenia Arredondo Pérez / Nelson Medina Torres

Avanzada Científica, Vol 3, Iss

2010 Volume 1

Abstract: Se describen los recursos de calor, luz y humedad de la empresa de cultivos varios "Lenin" de Matanzas a partir de las observaciones realizadas en la estación meteorológica Jovellanos durante el período 1967-1995. Se concluye que la empresa está bajo la ... ...

Abstract	Se describen los recursos de calor, luz y humedad de la empresa de cultivos varios "Lenin" de Matanzas a partir de las observaciones realizadas en la estación meteorológica Jovellanos durante el período 1967-1995. Se concluye que la empresa está bajo la influencia de los recursos climáticos necesarios para establecer agroecosistemas sostenibles.
Keywords	caracterización agroclimática ; agroecología ; Science (General) ; Q1-390 ; Science ; Q ; DOAJ:Science (General) ; DOAJ:Science General
Language	Spanish
Publishing date	2010-10-01T00:00:00Z
Publisher	Centro de Información y Gestión Tecnológica
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Características Agroclimática de la E. C. V. "V.I. Lenin" de Matanzas y potencial en la actividad agroecológica.

Nelson Medina Torres / María Eugenia Arredondo Pérez / Aida C. Ochoa Perdomo

Avanzada Científica, Vol 3, Iss

2010 Volume 1

Abstract	Se describen los recursos de calor, luz y humedad de la empresa de cultivos varios "Lenin" de Matanzas a partir de las observaciones realizadas en la estación meteorológica Jovellanos durante el período 1967-1995. Se concluye que la empresa está bajo la influencia de los recursos climáticos necesarios para establecer agroecosistemas sostenibles.
Keywords	caracterización agroclimática ; agroecología ; Science (General) ; Q1-390 ; Science ; Q
Language	Spanish
Publishing date	2010-10-01T00:00:00Z
Publisher	Centro de Información y Gestión Tecnológica
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Frecuencia e implicaciones clínicas del Anticoagulante Lúpico en pacientes con Insuficiencia Renal Crónica Estadio V en Programa de Hemodiálisis en Maracaibo, Venezuela.

Fernández-Abreu, Mary C / Diez-Ewald, María / Briceño, Soledad / Torres-Guerra, Enrique / Rodríguez, Zulay / Fernández, Nelson

Investigacion clinica

2007 Volume 48, Issue 1, Page(s) 69–79

Abstract: The objective of the present study was to determine the frequency of lupus anticoagulant (LA), in patients with terminal chronic renal failure (TCRF), and its association with thrombotic events. Sixty three patients were separated into two groups: Group ... ...

Title translation	Frequency and clinical implications of lupus anticoagulant in patients with terminal chronic renal failure in hemodialysis.
Abstract	The objective of the present study was to determine the frequency of lupus anticoagulant (LA), in patients with terminal chronic renal failure (TCRF), and its association with thrombotic events. Sixty three patients were separated into two groups: Group A, consisted of 32 patients under treatment with hemodialysis, and Group B was formed of 31 patients who were treated in a conservative manner. Presence of LA was found in 4 patients from Group A and none from Group B. Seven thrombotic events were registered, all in patients from Group A, and three of the episodes happened in 2 patients with LA, showing a statistically significant difference with LA negative patients from the same Group A (p < 0.001). Three of the LA positive patients suffered from type 2 diabetes and all of them had been under dialysis for less obtained by than 6 months. Vascular access was catheterization which means that 57.1% of patients with this type of procedure were positive for LA. The present results show a strong relationship between the presence of LA and thrombotic episodes in patients with TCRF, under hemodialysis with the use of catheter, instead of a permanent vascular access. Due to the fact that prolonged use of catheters for hemodialysis has been related to positive LA, it is advisable to screen patients under dialysis for the presence of this antibody, and to promote the prompt availability of a permanent vascular access, in order to prevent complications, such as thrombosis.
MeSH term(s)	Adolescent ; Adult ; Aged ; Arteriovenous Shunt, Surgical ; Case-Control Studies ; Catheterization/adverse effects ; Catheters, Indwelling ; Diabetic Nephropathies/complications ; Female ; Humans ; Incidence ; Infection/complications ; Kidney Failure, Chronic/blood ; Kidney Failure, Chronic/etiology ; Kidney Failure, Chronic/therapy ; Lupus Coagulation Inhibitor/blood ; Male ; Middle Aged ; Prevalence ; Prospective Studies ; Renal Dialysis ; Thrombophilia/blood ; Thrombophilia/epidemiology ; Thrombophilia/etiology ; Thrombosis/epidemiology ; Thrombosis/etiology ; Venezuela/epidemiology
Chemical Substances	Lupus Coagulation Inhibitor
Language	Spanish
Publishing date	2007-03
Publishing country	Venezuela
Document type	Comparative Study ; English Abstract ; Journal Article
ZDB-ID	969078-5
ISSN	0535-5133
ISSN	0535-5133
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Article: Decrease of selective immunoglobulin E response to amoxicillin despite repeated administration of benzylpenicillin and penicillin V.

Fernandez, T / Torres, M J / R-Pena, R / Fuentes, M S / Robles, S / Mayorga, C / Blanca, M

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology

2005 Volume 35, Issue 12, Page(s) 1645–1650

Abstract: ... in subjects with selective responses to amoxicillin (AX) and good tolerance to benzylpenicillin (BP) and penicillin V (PV ... followed-up for 2 years with the periodic administration of penicillin G and V (Group A) and compared ...

Abstract	Background: Subjects with IgE responses to betalactams can develop selective or cross-reactive responses after the administration of penicillin derivatives. After the reaction, however, the hapten induces a boosting phenomenon, which may increase the titre and the affinity of the antibody, with the resulting risk of developing allergic reactions to other penicillins. Objective: To determine in subjects with selective responses to amoxicillin (AX) and good tolerance to benzylpenicillin (BP) and penicillin V (PV) whether the administration of these compounds induced any change in specificity, measured by either skin or in vitro testing, which could predict the appearance of cross-reactivity. Methods: Ten subjects with a selective response to AX were followed-up for 2 years with the periodic administration of penicillin G and V (Group A) and compared with another group composed of 10 persons with identical clinical characteristics but without repeated penicillin administration (Group B). Periodic in vitro and in vivo measurements of specific IgE antibodies were performed at 6-month intervals. Patients were randomized to Group A or B according to their order of inclusion. Results: In both groups, skin test reactivity tended to decrease, and although greater in Group A, the difference was not significant compared with Group B. Median RAST values also decreased over time and showed no differences in the exposed group compared with the controls. One patient in Group A became positive to benzylpenicilloyl (BPO), despite becoming negative to AX. Conclusion: Subjects with selective IgE responses to side-chain-specific determinants seem to become negative, with no influence from subsequent administration of a closely related penicillin.
MeSH term(s)	Adolescent ; Adult ; Amoxicillin/adverse effects ; Antibodies, Anti-Idiotypic/blood ; Cross Reactions ; Drug Hypersensitivity/immunology ; Female ; Follow-Up Studies ; Humans ; Immunoglobulin E/blood ; Immunoglobulin E/immunology ; Male ; Middle Aged ; Penicillin G/administration & dosage ; Penicillin V/administration & dosage ; Radioallergosorbent Test ; Sensitivity and Specificity ; Skin Tests
Chemical Substances	Antibodies, Anti-Idiotypic ; Immunoglobulin E (37341-29-0) ; Amoxicillin (804826J2HU) ; Penicillin G (Q42T66VG0C) ; Penicillin V (Z61I075U2W)
Language	English
Publishing date	2005-12
Publishing country	England
Document type	Comparative Study ; Journal Article ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
ZDB-ID	645204-8
ISSN	1365-2222 ; 0954-7894 ; 0960-2178
ISSN (online)	1365-2222
ISSN	0954-7894 ; 0960-2178
DOI	10.1111/j.1365-2222.2005.02378.x
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Book ; Online: Molecular properties of gases of ODP Leg 204 sites, supplementary data to: Milkov, Alexei V; Claypool, George E; Lee, Young-Joo; Torres, Marta E; Borowski, Walter S; Tomaru, Hitoshi; Sassen, Roger; Long, Philip E; ODP Leg 204 Shipboard Scientific Party (2004): Ethane enrichment and propane depletion in subsurface gases indicate gas hydrate occurrence in marine sediments at southern Hydrate Ridge offshore Oregon. Organic Geochemistry, 35(9), 1067-1080

Milkov, Alexei V / Borowski, Walter S / Claypool, George E / Lee, Young-Joo / Long, Philip E / Sassen, Roger / Tomaru, Hitoshi / Torres, Marta E / ODP Leg 204 Shipboard Scientific Party

2004

Abstract: The recognition of finely disseminated gas hydrate in deep marine sediments heavily depends on various indirect techniques because this mineral quickly decomposes upon recovery from in situ pressure and temperature conditions. Here, we discuss molecular ... ...

Abstract	The recognition of finely disseminated gas hydrate in deep marine sediments heavily depends on various indirect techniques because this mineral quickly decomposes upon recovery from in situ pressure and temperature conditions. Here, we discuss molecular properties of closely spaced gas voids (formed as a result of core recovery) and gas hydrates from an area of relatively low gas flux at the flanks of the southern Hydrate Ridge offshore Oregon (ODP Sites 1244, 1245 and 1247). Within the gas hydrate occurrence zone (GHOZ), the concentration of ethane (C2) and propane (C3) in adjacent gas voids shows large variability. Sampled gas hydrates are enriched in C2 relative to void gases but do not contain C3. We suggest that the observed variations in the composition of void gases is a result of molecular fractionation during crystallization of structure I gas hydrate that contains C2 but excludes C3 from its crystal lattice. This hypothesis is used to identify discrete intervals of finely disseminated gas hydrate in cored sediments. Variations in gas composition help better constrain gas hydrate distribution near the top of the GHOZ along with variations in pore water chemistry and core temperature. Sediments near the base of the gas hydrate stability zone are relatively enriched in C2+ hydrocarbon gases. Complex and poorly understood geological and geochemical processes in these deeper sediments make the identification of gas hydrate based on molecular properties of void gases more ambiguous. The proposed technique appears to be a useful tool to better understand the distribution of gas hydrate in marine sediments and ultimately the role of gas hydrate in the global carbon cycle.
Language	English
Dates of publication	2004-9999
Size	Online-Ressource
Publisher	PANGAEA - Data Publisher for Earth & Environmental Science
Publishing place	Bremen/Bremerhaven
Document type	Book ; Online
Note	This dataset is supplement to doi:10.1016/j.orggeochem.2004.04.003
DOI	10.1594/PANGAEA.763253
Database	Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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Book ; Conference proceedings ; Online: Carbon and deuterium isotopes and C ratios in gas hydrates of ODP Leg 204 sites, supplementary data to: Claypool, George E; Milkov, Alexei V; Lee, Young-Joo; Torres, Marta E; Borowski, Walter S; Tomaru, Hitoshi (2006): Microbial methane generation and gas transport in shallow sediments of an accretionary complex, southern Hydrate Ridge (ODP Leg 204), offshore Oregon, USA. In: Tr?hu, AM; Bohrmann, G; Torres, ME; Colwell, FS (eds.), Proceedings of the Ocean Drilling Program, Scientific Results, College Station, TX (Ocean Drilling Program), 204, 1-52

Claypool, George E / Borowski, Walter S / Lee, Young-Joo / Milkov, Alexei V / Tomaru, Hitoshi / Torres, Marta E

2006

Abstract: Sediments at the southern summit of Hydrate Ridge display two distinct modes of gas hydrate occurrence. The dominant mode is associated with active venting of gas exsolved from the accretionary prism and leads to high concentrations (15%-40% of pore ... ...

Abstract	Sediments at the southern summit of Hydrate Ridge display two distinct modes of gas hydrate occurrence. The dominant mode is associated with active venting of gas exsolved from the accretionary prism and leads to high concentrations (15%-40% of pore space) of gas hydrate in seafloor or near-surface sediments at and around the topographic summit of southern Hydrate Ridge. These near-surface gas hydrates are mainly composed of previously buried microbial methane but also contain a significant (10%-15%) component of thermogenic hydrocarbons and are overprinted with microbial methane currently being generated in shallow sediments. Focused migration pathways with high gas saturation (>65%) abutting the base of gas hydrate stability create phase equilibrium conditions that permit the flow of a gas phase through the gas hydrate stability zone. Gas seepage at the summit supports rapid growth of gas hydrates and vigorous anaerobic methane oxidation. The other mode of gas hydrate occurs in slope basins and on the saddle north of the southern summit and consists of lower average concentrations (0.5%-5%) at greater depths (30-200 meters below seafloor [mbsf]) resulting from the buildup of in situ-generated dissolved microbial methane that reaches saturation levels with respect to gas hydrate stability at 30-50 mbsf. Net rates of sulfate reduction in the slope basin and ridge saddle sites estimated from curve fitting of concentration gradients are 2-4 mmol/m3/yr, and integrated net rates are 20-50 mmol/m2/yr. Modeled microbial methane production rates are initially 1.5 mmol/m3/yr in sediments just beneath the sulfate reduction zone but rapidly decrease to rates of <0.1 mmol/m3/yr at depths >100 mbsf. Integrated net rates of methane production in sediments away from the southern summit of Hydrate Ridge are 25-80 mmol/m**2/yr. Anaerobic methane oxidation is minor or absent in cored sediments away from the summit of southern Hydrate Ridge. Ethane-enriched Structure I gas hydrate solids are buried more rapidly than ethane-depleted dissolved gas in the pore water because of advection from compaction. With subsidence beneath the gas hydrate stability zone, the ethane (mainly of low-temperature thermogenic origin) is released back to the dissolved gas-free gas phases and produces a discontinuous decrease in the C1/C2 vs. depth trend. These ethane fractionation effects may be useful to recognize and estimate levels of gas hydrate occurrence in marine sediments.
Language	English
Dates of publication	2006-9999
Size	Online-Ressource
Publisher	PANGAEA - Data Publisher for Earth & Environmental Science
Publishing place	Bremen/Bremerhaven
Document type	Book ; Conference proceedings ; Online
Note	This dataset is supplement to doi:10.2973/odp.proc.sr.204.113.2006
DOI	10.1594/PANGAEA.774729
Database	Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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Book ; Online: Spacing and amplitude of IR temperature anomalies and hydrate content of sediments from ODP Leg 304 sites (Table 1), supplementary data to: Tréhu, Anne M; Long, Philip E; Torres, Marta E; Bohrmann, Gerhard; Rack, Frank R; Collett, Tim S; Goldberg, D S; Milkov, Alexei V; Riedel, Michael; Schultheiss, P; Bangs, N L; Barr, Samantha R; Borowski, Walter S; Claypool, George E; Delwiche, Mark E; Dickens, Gerald Roy; Gràcia, Eulàlia; Guerin, Gilles; Holland, M; Johnson, JE; Lee, Young-Joo; Liu, C-S; Su, Xin; Teichert, Barbara MA; Tomaru, Hitoshi; Vanneste, M; Watanabe, Mahito; Weinberger, J L (2004): Three-dimensional distribution of gas hydrate beneath southern Hydrate Ridge: constraints from ODP Leg 204. Earth and Planetary Science Letters, 222(3-4), 845-862

Tréhu, Anne M / Bohrmann, Gerhard / Collett, Tim S / Goldberg, D S / Long, Philip E / Milkov, Alexei V / Rack, Frank R / Riedel, Michael / Torres, Marta E / al., et

2004

Abstract: Large uncertainties about the energy resource potential and role in global climate change of gas hydrates result from uncertainty about how much hydrate is contained in marine sediments. During Leg 204 of the Ocean Drilling Program (ODP) to the ... ...

Abstract	Large uncertainties about the energy resource potential and role in global climate change of gas hydrates result from uncertainty about how much hydrate is contained in marine sediments. During Leg 204 of the Ocean Drilling Program (ODP) to the accretionary complex of the Cascadia subduction zone, we sampled the gas hydrate stability zone (GHSZ) from the seafloor to its base in contrasting geological settings defined by a 3D seismic survey. By integrating results from different methods, including several new techniques developed for Leg 204, we overcome the problem of spatial under-sampling inherent in robust methods traditionally used for estimating the hydrate content of cores and obtain a high-resolution, quantitative estimate of the total amount and spatial variability of gas hydrate in this structural system. We conclude that high gas hydrate content (30-40% of pore space or 20-26% of total volume) is restricted to the upper tens of meters below the seafloor near the summit of the structure, where vigorous fluid venting occurs. Elsewhere, the average gas hydrate content of the sediments in the gas hydrate stability zone is generally <2% of the pore space, although this estimate may increase by a factor of 2 when patchy zones of locally higher gas hydrate content are included in the calculation. These patchy zones are structurally and stratigraphically controlled, contain up to 20% hydrate in the pore space when averaged over zones ~10 m thick, and may occur in up to ~20% of the region imaged by 3D seismic data. This heterogeneous gas hydrate distribution is an important constraint on models of gas hydrate formation in marine sediments and the response of the sediments to tectonic and environmental change.
Language	English
Dates of publication	2004-9999
Size	Online-Ressource
Publisher	PANGAEA - Data Publisher for Earth & Environmental Science
Publishing place	Bremen/Bremerhaven
Document type	Book ; Online
Note	This dataset is supplement to doi:10.1016/j.epsl.2004.03.035
DOI	10.1594/PANGAEA.722485
Database	Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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Article: Serine-Arginine Protein Kinase SRPK2 Modulates the Assembly of the Active Zone Scaffolding Protein CAST1/ERC2

Arancibia Radich, Duxan / Lira, Matías / Garner, Craig / Gundelfinger, Eckart / Zamorano, Pedro / Torres, Viviana

Cells, 8(11):1333

2019

Abstract: Neurons release neurotransmitters at a specialized region of the presynaptic membrane, the active zone (AZ), where a complex meshwork of proteins organizes the release apparatus. The formation of this proteinaceous cytomatrix at the AZ (CAZ) depends on ... ...

Institution	Leibniz-Institut für Neurobiologie
Abstract	Neurons release neurotransmitters at a specialized region of the presynaptic membrane, the active zone (AZ), where a complex meshwork of proteins organizes the release apparatus. The formation of this proteinaceous cytomatrix at the AZ (CAZ) depends on precise homo- and hetero-oligomerizations of distinct CAZ proteins. The CAZ protein CAST1/ERC2 contains four coiled-coil (CC) domains that interact with other CAZ proteins, but also promote self-assembly, which is an essential step for its integration during AZ formation. The self-assembly and synaptic recruitment of the Drosophila protein Bruchpilot (BRP), a partial homolog of CAST1/ERC2, is modulated by the serine-arginine protein kinase (SRPK79D). Here, we demonstrate that overexpression of the vertebrate SRPK2 regulates the self-assembly of CAST1/ERC2 in HEK293T, SH-SY5Y and HT-22 cells and the CC1 and CC4 domains are involved in this process. Moreover, the isoform SRPK2 forms a complex with CAST1/ERC2 when co-expressed in HEK293T and SH-SY5Y cells. More importantly, SRPK2 is present in brain synaptic fractions and synapses, suggesting that this protein kinase might control the level of self-aggregation of CAST1/ERC2 in synapses, and thereby modulate presynaptic assembly.
Keywords	CAST1/ERC2 ; SRPK ; coiled-coil ; active zone ; self-aggregation ; synapse
Language	English
Document type	Article
Database	Repository for Life Sciences

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Article ; Online: Reactive Oxygen Species and Redox Signaling in Chronic Kidney Disease.

Irazabal, Maria V / Torres, Vicente E

Cells

2020 Volume 9, Issue 6

Abstract: Chronic kidney disease (CKD) remains a worldwide public health problem associated with serious complications and increased mortality rates. Accumulating evidence indicates that elevated intracellular levels of reactive oxygen species (ROS) play a major ... ...

Abstract	Chronic kidney disease (CKD) remains a worldwide public health problem associated with serious complications and increased mortality rates. Accumulating evidence indicates that elevated intracellular levels of reactive oxygen species (ROS) play a major role in the pathogenesis of CKD. Increased intracellular levels of ROS can lead to oxidation of lipids, DNA, and proteins, contributing to cellular damage. On the other hand, ROS are also important secondary messengers in cellular signaling. Consequently, normal kidney cell function relies on the "right" amount of ROS. Mitochondria and NADPH oxidases represent major sources of ROS in the kidney, but renal antioxidant systems, such as superoxide dismutase, catalase, or glutathione peroxidase counterbalance ROS-mediated injury. This review discusses the main sources of ROS and antioxidant systems in the kidney, and redox signaling pathways leading to inflammation and fibrosis, which result in abnormal kidney function and CKD progression. We further discuss the important role of the nuclear factor erythroid 2-related factor 2 (Nrf2) in regulating antioxidant responses, and other mechanisms of redox signaling.
MeSH term(s)	Animals ; Antioxidants/metabolism ; Humans ; Kidney/metabolism ; Kidney/pathology ; Oxidation-Reduction ; Reactive Oxygen Species/metabolism ; Renal Insufficiency, Chronic/metabolism ; Signal Transduction
Chemical Substances	Antioxidants ; Reactive Oxygen Species
Language	English
Publishing date	2020-05-28
Publishing country	Switzerland
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Review
ZDB-ID	2661518-6
ISSN	2073-4409 ; 2073-4409
ISSN (online)	2073-4409
ISSN	2073-4409
DOI	10.3390/cells9061342
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Implications of the three-dimensional chromatin organization for genome evolution in a fungal plant pathogen.

Torres, David E / Kramer, H Martin / Tracanna, Vittorio / Fiorin, Gabriel L / Cook, David E / Seidl, Michael F / Thomma, Bart P H J

Nature communications

2024 Volume 15, Issue 1, Page(s) 1701

Abstract: ... segmental duplications. Notably, the patterns observed for V. dahliae are also present in other Verticillium species ...

Abstract	The spatial organization of eukaryotic genomes is linked to their biological functions, although it is not clear how this impacts the overall evolution of a genome. Here, we uncover the three-dimensional (3D) genome organization of the phytopathogen Verticillium dahliae, known to possess distinct genomic regions, designated adaptive genomic regions (AGRs), enriched in transposable elements and genes that mediate host infection. Short-range DNA interactions form clear topologically associating domains (TADs) with gene-rich boundaries that show reduced levels of gene expression and reduced genomic variation. Intriguingly, TADs are less clearly insulated in AGRs than in the core genome. At a global scale, the genome contains bipartite long-range interactions, particularly enriched for AGRs and more generally containing segmental duplications. Notably, the patterns observed for V. dahliae are also present in other Verticillium species. Thus, our analysis links 3D genome organization to evolutionary features conserved throughout the Verticillium genus.
MeSH term(s)	Plants/genetics ; Genomics ; DNA Transposable Elements/genetics ; Chromatin/genetics ; Evolution, Molecular ; Genome, Fungal/genetics
Chemical Substances	DNA Transposable Elements ; Chromatin
Language	English
Publishing date	2024-02-24
Publishing country	England
Document type	Journal Article
ZDB-ID	2553671-0
ISSN	2041-1723 ; 2041-1723
ISSN (online)	2041-1723
ISSN	2041-1723
DOI	10.1038/s41467-024-45884-x
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