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Article ; Online: Preoperative sclerotherapy of facial venous malformations: impact on surgical parameters and long-term follow-up.

James, Charles A / Braswell, Leah E / Wright, Lonnie B / Roberson, Paula K / Moore, Mary B / Waner, Milton / Buckmiller, Lisa M

Journal of vascular and interventional radiology : JVIR

2011 Volume 22, Issue 7, Page(s) 953–960

Abstract: Purpose: To analyze the operative benefit of preoperative sclerotherapy of facial venous malformations and assess long-term patient outcome.: Materials and methods: Preoperative sclerotherapy was performed in 24 consecutive patients referred before ... ...

Abstract	Purpose: To analyze the operative benefit of preoperative sclerotherapy of facial venous malformations and assess long-term patient outcome. Materials and methods: Preoperative sclerotherapy was performed in 24 consecutive patients referred before resection of facial venous malformation. Pretreatment imaging was reviewed for malformation dimensions (length, width, and height), and volumes were estimated. Sclerotherapy was performed with 3% sodium tetradecyl in the first 15 patients and 98% dehydrated alcohol in the remaining 9 patients. Operative blood loss, operative time, transfusion requirement, and hospital stay were recorded. Operative time per lesion volume and operative blood loss per lesion volume were calculated. Results were compared with 15 historical control patients who underwent resection of facial venous malformations without preoperative sclerotherapy. Long-term follow-up of study and control patients was performed. Results: Compared with controls, patients undergoing preoperative venous sclerotherapy were significantly older (P = .0206) and had larger lesions in all three dimensions (height, P = .0002; length, P = .0010; width, P = .0004). Patients receiving sclerotherapy had shorter operative time per lesion volume (P < .0001) and reduced blood loss per lesion volume (P < .0001). Neither hospital stay nor the need for blood transfusion differed from the control patients (P = .2449 and P = .6857). Mild periprocedural complications were encountered in 12.5% of cases, and nerve paresis occurred in 8.3% of cases. Long-term follow-up revealed retreatment was required in 2 of 24 patients (8.3%). Conclusions: Preoperative sclerotherapy of venous malformations was associated with less operative time per lesion volume and less operative blood loss per lesion volume. Long-term follow-up revealed a low need for retreatment.
MeSH term(s)	Adolescent ; Adult ; Blood Loss, Surgical/prevention & control ; Case-Control Studies ; Child ; Child, Preschool ; Face/blood supply ; Female ; Follow-Up Studies ; Humans ; Infant ; Length of Stay ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Preoperative Care ; Sclerotherapy/adverse effects ; Time Factors ; Treatment Outcome ; Vascular Malformations/diagnosis ; Vascular Malformations/surgery ; Vascular Malformations/therapy ; Vascular Surgical Procedures/adverse effects ; Veins/abnormalities ; Veins/surgery ; Young Adult
Language	English
Publishing date	2011-07
Publishing country	United States
Document type	Journal Article
ZDB-ID	1137756-2
ISSN	1535-7732 ; 1051-0443
ISSN (online)	1535-7732
ISSN	1051-0443
DOI	10.1016/j.jvir.2011.03.004
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Article: Changes in ultrasonographic echogenicity and visibility of needles with changes in angles of insonation.

Nichols, Kremer / Wright, Lonnie B / Spencer, Trey / Culp, William C

Journal of vascular and interventional radiology : JVIR

2003 Volume 14, Issue 12, Page(s) 1553–1557

Abstract: Purpose: To objectively compare the echogenicity of several types of needles at clinically important angles of insonation.: Materials and methods: Four commercial needles (Echotip, Mini-Stick, Echo-Coat, Surflo) and a prototype dimpled needle were ... ...

Abstract	Purpose: To objectively compare the echogenicity of several types of needles at clinically important angles of insonation. Materials and methods: Four commercial needles (Echotip, Mini-Stick, Echo-Coat, Surflo) and a prototype dimpled needle were tested in a liver phantom at angles of insonation ranging from 90 degrees to 15 degrees. Photodensity measurement determined echogenicity levels in arbitrary echogenicity units (EU). Results: At 90 degrees angles of insonation all needles were easily seen (60-76 EU) and echogenic levels were similar (P =.264). All values decreased with angulation. From the 35 degrees to 15 degrees angles, the prototype and Echotip needles were superior (P <.05). At 15 degrees the values were 43 EU for the prototype needle, 40 EU for the Echotip needle, 9.0 EU for the Echo-Coat needle, and 5.0 EU for the Surflo needle. Conclusion: With angulation, all needles drop in echogenicity, with prototype dimpled and Echotip best maintaining visibility at clinically important angles.
MeSH term(s)	Liver/diagnostic imaging ; Needles ; Phantoms, Imaging ; Ultrasonography
Language	English
Publishing date	2003-10-21
Publishing country	United States
Document type	Comparative Study ; Journal Article
ZDB-ID	1137756-2
ISSN	1535-7732 ; 1051-0443
ISSN (online)	1535-7732
ISSN	1051-0443
DOI	10.1097/01.rvi.0000099527.29957.a6
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Article ; Online: Corrigendum: Three keys to the radiation of angiosperms into freezing environments.

Zanne, Amy E / Tank, David C / Cornwell, William K / Eastman, Jonathan M / Smith, Stephen A / FitzJohn, Richard G / McGlinn, Daniel J / O'Meara, Brian C / Moles, Angela T / Reich, Peter B / Royer, Dana L / Soltis, Douglas E / Stevens, Peter F / Westoby, Mark / Wright, Ian J / Aarssen, Lonnie / Bertin, Robert I / Calaminus, Andre / Govaerts, Rafaël /

Hemmings, Frank / Leishman, Michelle R / Oleksyn, Jacek / Soltis, Pamela S / Swenson, Nathan G / Warman, Laura / Beaulieu, Jeremy M

Nature

2015 Volume 521, Issue 7552, Page(s) 380

Language	English
Publishing date	2015-05-21
Publishing country	England
Document type	Published Erratum
ZDB-ID	120714-3
ISSN	1476-4687 ; 0028-0836
ISSN (online)	1476-4687
ISSN	0028-0836
DOI	10.1038/nature14371
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Article: Complication rate of venous access procedures performed by a radiology practitioner assistant compared with interventional radiology physicians and supervised trainees.

Benham, Joseph R / Culp, William C / Wright, Lonnie B / McCowan, Timothy C

Journal of vascular and interventional radiology : JVIR

2007 Volume 18, Issue 8, Page(s) 1001–1004

Abstract: Purpose: To compare venous access complication rates associated with procedures performed by radiology practitioner assistants (RPAs) versus interventional radiology (IR) faculty members, IR fellows, and radiology residents.: Materials and methods: A ...

Abstract	Purpose: To compare venous access complication rates associated with procedures performed by radiology practitioner assistants (RPAs) versus interventional radiology (IR) faculty members, IR fellows, and radiology residents. Materials and methods: A retrospective review of venous access procedures in the IR department for 12 consecutive months at a single university hospital was performed. Procedural primary operators included 12 radiology residents, two IR fellows, four IR faculty members, and one board-certified RPA with 2 years of university training. Data examined included immediate and short-term complications separated into major and overall categories. Results: A total of 2093 venous access procedures were performed. The RPA performed 670 procedures (temporary central venous catheter placement, n = 274; peripherally inserted central catheter, n = 67; venous access catheter change, n = 99; venous port placement, n = 126; tunneled central venous catheter placement, n = 39; catheter check, n = 32; and venous explant, n = 43). Similar procedure ratios were noted with faculty members, fellows, and residents. Procedures by the RPA had a major complication rate of 0.29% and an overall complication rate of 0.89%. Four IR faculty members performed 291 procedures, with no major complications and an overall complication rate of 1.71%. Two IR fellows performed 562 procedures, with a major complication rate of 0.35% and an overall complication rate of 1.06%. Twelve residents performed 570 procedures, with a major complication rate of 0.52% (range, 0%-2.46%) and an overall complication rate of 1.39% (range, 0%-3.70%). No significant difference was found among groups (P = .7). Conclusion: A properly trained and monitored RPA can safely perform selected venous access procedures with complication rates equal to those of IR faculty members, fellows, and residents.
MeSH term(s)	Catheterization, Central Venous/adverse effects ; Catheterization, Peripheral/adverse effects ; Equipment Safety ; Fellowships and Scholarships/statistics & numerical data ; Humans ; Internship and Residency/statistics & numerical data ; Physician Assistants/education ; Physician Assistants/statistics & numerical data ; Physicians/statistics & numerical data ; Radiology, Interventional/education ; Radiology, Interventional/manpower ; Retrospective Studies ; Time Factors ; Treatment Outcome
Language	English
Publishing date	2007-08
Publishing country	United States
Document type	Comparative Study ; Journal Article
ZDB-ID	1137756-2
ISSN	1535-7732 ; 1051-0443
ISSN (online)	1535-7732
ISSN	1051-0443
DOI	10.1016/j.jvir.2007.05.014
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Article ; Online: Zanne et al. reply.

Hemmings, Frank / Leishman, Michelle R / Oleksyn, Jacek / Soltis, Pamela S / Swenson, Nathan G / Warman, Laura / Beaulieu, Jeremy M

Nature

2015 Volume 521, Issue 7552, Page(s) E6–7

MeSH term(s)	Biological Evolution ; Cold Climate ; Ecosystem ; Freezing ; Magnoliopsida/anatomy & histology ; Magnoliopsida/physiology ; Xylem/anatomy & histology
Language	English
Publishing date	2015-05-21
Publishing country	England
Document type	Letter ; Comment
ZDB-ID	120714-3
ISSN	1476-4687 ; 0028-0836
ISSN (online)	1476-4687
ISSN	0028-0836
DOI	10.1038/nature14394
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Article: Paravertebral block: an improved method of pain control in percutaneous transhepatic biliary drainage.

Culp, William C / McCowan, Timothy C / DeValdenebro, Miguel / Wright, Lonnie B / Workman, James L

Cardiovascular and interventional radiology

2006 Volume 29, Issue 6, Page(s) 1015–1021

Abstract: Background and purpose: Percutaneous transhepatic biliary drainage remains a painful procedure in many cases despite the routine use of large amounts of intravenous sedation. We present a feasibility study of thoracic paravertebral blocks in an effort ... ...

Abstract	Background and purpose: Percutaneous transhepatic biliary drainage remains a painful procedure in many cases despite the routine use of large amounts of intravenous sedation. We present a feasibility study of thoracic paravertebral blocks in an effort to reduce pain during and following the procedure and reduce requirements for intravenous sedation. Methods: Ten consecutive patients undergoing biliary drainage procedures received fluoroscopically guided paravertebral blocks and then had supplemental intravenous sedation as required to maintain patient comfort. Levels T8-T9 and T9-T10 on the right were targeted with 10-20 ml of 0.5% bupivacaine. Sedation requirements and pain levels were recorded. Results: Ten biliary drainage procedures in 8 patients were performed for malignancy in 8 cases and for stones in 2. The mean midazolam use was 1.13 mg i.v., and the mean fentanyl requirement was 60.0 microg i.v. in the block patients. Two episodes of hypotension, which responded promptly to volume replacement, may have been related to the block. No serious complications were encountered. The mean pain score when traversing the chest wall, liver capsule, and upon entering the bile ducts was 0.1 on a scale of 0 to 10, with 1 patient reporting a pain level of 1 and 9 reporting 0. The mean peak pain score, encountered when manipulating at the common bile duct level or when addressing stones there, was 5.4 and ranged from 0 to 10. Conclusions: Thoracic paravertebral block with intravenous sedation supplementation appears to be a feasible method of pain control during biliary interventions.
MeSH term(s)	Adult ; Aged ; Anesthesia, Spinal/adverse effects ; Anesthesia, Spinal/methods ; Anesthetics, Intravenous ; Anesthetics, Local ; Bile Duct Neoplasms/complications ; Bile Duct Neoplasms/therapy ; Bupivacaine ; Cholestasis/etiology ; Cholestasis/therapy ; Drainage/adverse effects ; Feasibility Studies ; Female ; Fentanyl ; Gallstones/therapy ; Humans ; Lidocaine ; Male ; Midazolam ; Middle Aged ; Pain/etiology ; Pain/prevention & control ; Pain Measurement ; Treatment Outcome
Chemical Substances	Anesthetics, Intravenous ; Anesthetics, Local ; Lidocaine (98PI200987) ; Midazolam (R60L0SM5BC) ; Fentanyl (UF599785JZ) ; Bupivacaine (Y8335394RO)
Language	English
Publishing date	2006-11
Publishing country	United States
Document type	Journal Article
ZDB-ID	603082-8
ISSN	1432-086X ; 0174-1551 ; 0342-7196
ISSN (online)	1432-086X
ISSN	0174-1551 ; 0342-7196
DOI	10.1007/s00270-005-0273-z
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Article ; Online: Popliteal artery disease: diagnosis and treatment.

Wright, Lonnie B / Matchett, W Jean / Cruz, Carlos P / James, Charles A / Culp, William C / Eidt, John F / McCowan, Timothy C

Radiographics : a review publication of the Radiological Society of North America, Inc

2004 Volume 24, Issue 2, Page(s) 467–479

Abstract: The popliteal artery is a relatively short vascular segment but is affected by a unique set of pathologic conditions. These conditions, which may be common throughout the arterial system or exclusive to the popliteal artery, include atherosclerosis, ... ...

Abstract	The popliteal artery is a relatively short vascular segment but is affected by a unique set of pathologic conditions. These conditions, which may be common throughout the arterial system or exclusive to the popliteal artery, include atherosclerosis, popliteal artery aneurysm, arterial embolus, trauma, popliteal artery entrapment syndrome, and cystic adventitial disease. The clinical manifestations, imaging appearances, and treatment options associated with these pathologic conditions differ significantly. Consequently, the radiologist should be familiar with these conditions to direct imaging for accurate diagnosis and treatment and to prevent loss of limb.
MeSH term(s)	Adolescent ; Adult ; Aged ; Aneurysm/diagnosis ; Aneurysm/diagnostic imaging ; Aneurysm/pathology ; Aneurysm/therapy ; Angiography/methods ; Anticoagulants/therapeutic use ; Arterial Occlusive Diseases/diagnosis ; Arterial Occlusive Diseases/diagnostic imaging ; Arterial Occlusive Diseases/pathology ; Arterial Occlusive Diseases/therapy ; Arteriosclerosis/diagnosis ; Arteriosclerosis/diagnostic imaging ; Arteriosclerosis/pathology ; Arteriosclerosis/therapy ; Constriction, Pathologic ; Cysts/complications ; Embolism/diagnosis ; Embolism/diagnostic imaging ; Embolism/drug therapy ; Embolism/pathology ; Embolism/therapy ; Female ; Femoral Artery/pathology ; Femoral Artery/surgery ; Humans ; Ischemia/etiology ; Ischemia/therapy ; Leg/blood supply ; Magnetic Resonance Imaging ; Male ; Popliteal Artery/diagnostic imaging ; Popliteal Artery/injuries ; Popliteal Artery/pathology ; Popliteal Artery/surgery ; Pressure ; Vascular Diseases/diagnosis ; Vascular Diseases/diagnostic imaging ; Vascular Diseases/pathology ; Vascular Diseases/therapy
Chemical Substances	Anticoagulants
Language	English
Publishing date	2004-03
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	603172-9
ISSN	1527-1323 ; 0271-5333
ISSN (online)	1527-1323
ISSN	0271-5333
DOI	10.1148/rg.242035117
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Article: Functional distinctiveness of major plant lineages

Cornwell, William K / Westoby, Mark / Falster, Daniel S / FitzJohn, Richard G / O'Meara, Brian C / Pennell, Matthew W / McGlinn, Daniel J / Eastman, Jonathan M / Moles, Angela T / Reich, Peter B / Tank, David C / Wright, Ian J / Aarssen, Lonnie / Beaulieu, Jeremy M / Kooyman, Robert M / Leishman, Michelle R / Miller, Eliot T / Niinemets, Ülo / Oleksyn, Jacek /

Ordonez, Alejandro / Royer, Dana L / Smith, Stephen A / Stevens, Peter F / Warman, Laura / Wilf, Peter / Zanne, Amy E / Austin, Amy

Journal of ecology. 2014 Mar., v. 102, no. 2

2014

Abstract: Plant traits vary widely across species and underpin differences in ecological strategy. Despite centuries of interest, the contributions of different evolutionary lineages to modern‐day functional diversity remain poorly quantified. Expanding data bases ...

Abstract	Plant traits vary widely across species and underpin differences in ecological strategy. Despite centuries of interest, the contributions of different evolutionary lineages to modern‐day functional diversity remain poorly quantified. Expanding data bases of plant traits plus rapidly improving phylogenies enable for the first time a data‐driven global picture of plant functional diversity across the major clades of higher plants. We mapped five key traits relevant to metabolism, resource competition and reproductive strategy onto a phylogeny across 48324 vascular plant species world‐wide, along with climate and biogeographic data. Using a novel metric, we test whether major plant lineages are functionally distinctive. We then highlight the trait–lineage combinations that are most functionally distinctive within the present‐day spread of ecological strategies. For some trait–clade combinations, knowing the clade of a species conveys little information to neo‐ and palaeo‐ecologists. In other trait–clade combinations, the clade identity can be highly revealing, especially informative clade–trait combinations include Proteaceae, which is highly distinctive, representing the global slow extreme of the leaf economic spectrum. Magnoliidae and Rosidae contribute large leaf sizes and seed masses and have distinctively warm, wet climatic distributions. Synthesis. This analysis provides a shortlist of the most distinctive trait–lineage combinations along with their geographic and climatic context: a global view of extant functional diversity across the tips of the vascular plant phylogeny.
Keywords	Proteaceae ; climate ; databases ; functional diversity ; leaves ; metabolism ; phylogeny
Language	English
Dates of publication	2014-03
Size	p. 345-356.
Document type	Article
ZDB-ID	3023-5
ISSN	0022-0477
ISSN	0022-0477
DOI	10.1111/1365-2745.12208
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Article ; Online: (with research data) Three keys to the radiation of angiosperms into freezing environments.

Hemmings, Frank / Leishman, Michelle R / Oleksyn, Jacek / Soltis, Pamela S / Swenson, Nathan G / Warman, Laura / Beaulieu, Jeremy M

Nature

2013 Volume 506, Issue 7486, Page(s) 89–92

Abstract: Early flowering plants are thought to have been woody species restricted to warm habitats. This lineage has since radiated into almost every climate, with manifold growth forms. As angiosperms spread and climate changed, they evolved mechanisms to cope ... ...

Abstract	Early flowering plants are thought to have been woody species restricted to warm habitats. This lineage has since radiated into almost every climate, with manifold growth forms. As angiosperms spread and climate changed, they evolved mechanisms to cope with episodic freezing. To explore the evolution of traits underpinning the ability to persist in freezing conditions, we assembled a large species-level database of growth habit (woody or herbaceous; 49,064 species), as well as leaf phenology (evergreen or deciduous), diameter of hydraulic conduits (that is, xylem vessels and tracheids) and climate occupancies (exposure to freezing). To model the evolution of species' traits and climate occupancies, we combined these data with an unparalleled dated molecular phylogeny (32,223 species) for land plants. Here we show that woody clades successfully moved into freezing-prone environments by either possessing transport networks of small safe conduits and/or shutting down hydraulic function by dropping leaves during freezing. Herbaceous species largely avoided freezing periods by senescing cheaply constructed aboveground tissue. Growth habit has long been considered labile, but we find that growth habit was less labile than climate occupancy. Additionally, freezing environments were largely filled by lineages that had already become herbs or, when remaining woody, already had small conduits (that is, the trait evolved before the climate occupancy). By contrast, most deciduous woody lineages had an evolutionary shift to seasonally shedding their leaves only after exposure to freezing (that is, the climate occupancy evolved before the trait). For angiosperms to inhabit novel cold environments they had to gain new structural and functional trait solutions; our results suggest that many of these solutions were probably acquired before their foray into the cold.
MeSH term(s)	Biological Evolution ; Cold Climate ; Ecosystem ; Freezing ; Likelihood Functions ; Magnoliopsida/anatomy & histology ; Magnoliopsida/physiology ; Phylogeography ; Plant Leaves/anatomy & histology ; Plant Leaves/physiology ; Seeds/physiology ; Time Factors ; Wood/anatomy & histology ; Wood/physiology ; Xylem/anatomy & histology ; Xylem/physiology
Language	English
Publishing date	2013-12-22
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
ZDB-ID	120714-3
ISSN	1476-4687 ; 0028-0836
ISSN (online)	1476-4687
ISSN	0028-0836
DOI	10.1038/nature12872
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Article: Which is a better predictor of plant traits: temperature or precipitation?

Moles, Angela T / Perkins, Sarah E / Laffan, Shawn W / Flores‐Moreno, Habacuc / Awasthy, Monica / Tindall, Marianne L / Sack, Lawren / Pitman, Andy / Kattge, Jens / Aarssen, Lonnie W / Anand, Madhur / Bahn, Michael / Blonder, Benjamin / Cavender‐Bares, Jeannine / Cornelissen, J. Hans C / Cornwell, Will K / Díaz, Sandra / Dickie, John B / Freschet, Grégoire T /

Griffiths, Joshua G / Gutierrez, Alvaro G / Hemmings, Frank A / Hickler, Thomas / Hitchcock, Timothy D / Keighery, Matthew / Kleyer, Michael / Kurokawa, Hiroko / Leishman, Michelle R / Liu, Kenwin / Niinemets, Ülo / Onipchenko, Vladimir / Onoda, Yusuke / Penuelas, Josep / Pillar, Valério D / Reich, Peter B / Shiodera, Satomi / Siefert, Andrew / Sosinski, Enio E., Jr / Soudzilovskaia, Nadejda A / Swaine, Emily K / Swenson, Nathan G / Bodegom, Peter M / Warman, Laura / Weiher, Evan / Wright, Ian J / Zhang, Hongxiang / Zobel, Martin / Bonser, Stephen P / Helm, Aveliina

Journal of vegetation science. 2014 Sept., v. 25, no. 5

2014

Abstract: QUESTION: Are plant traits more closely correlated with mean annual temperature, or with mean annual precipitation? LOCATION: Global. METHODS: We quantified the strength of the relationships between temperature and precipitation and 21 plant traits from ... ...

Abstract	QUESTION: Are plant traits more closely correlated with mean annual temperature, or with mean annual precipitation? LOCATION: Global. METHODS: We quantified the strength of the relationships between temperature and precipitation and 21 plant traits from 447,961 species‐site combinations worldwide. We used meta‐analysis to provide an overall answer to our question. RESULTS: Mean annual temperature was significantly more strongly correlated with plant traits than was mean annual precipitation. CONCLUSIONS: Our study provides support for some of the assumptions of classical vegetation theory, and points to many interesting directions for future research. The relatively low R² values for precipitation might reflect the weak link between mean annual precipitation and the availability of water to plants.
Keywords	atmospheric precipitation ; plant available water ; temperature ; vegetation
Language	English
Dates of publication	2014-09
Size	p. 1167-1180.
Publishing place	Opulus Press
Document type	Article
ZDB-ID	1053769-7
ISSN	1100-9233
ISSN	1100-9233
DOI	10.1111/jvs.12190
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