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  1. Article ; Online: Recent estimates of alcohol specific deaths support alcohol minimum unit pricing.

    Wyper, Grant M A / Giles, Lucie / Beeston, Clare / Shivaji, Tara

    BMJ (Clinical research ed.)

    2024  Volume 384, Page(s) q765

    MeSH term(s) Humans ; Ethanol ; Alcoholic Beverages ; Costs and Cost Analysis ; Alcohol Drinking/epidemiology ; Commerce
    Chemical Substances Ethanol (3K9958V90M)
    Language English
    Publishing date 2024-03-28
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 1362901-3
    ISSN 1756-1833 ; 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    ISSN (online) 1756-1833
    ISSN 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    DOI 10.1136/bmj.q765
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Trends in healthy life expectancy in the age of austerity.

    Walsh, David / Wyper, Grant M A / McCartney, Gerry

    Journal of epidemiology and community health

    2022  

    Abstract: Background: Worrying changes in life expectancy trends have been observed recently in the UK, largely attributed to austerity policies introduced over the last decade. To incorporate changes to quality, rather than just length of, life, our aim was to ... ...

    Abstract Background: Worrying changes in life expectancy trends have been observed recently in the UK, largely attributed to austerity policies introduced over the last decade. To incorporate changes to quality, rather than just length of, life, our aim was to describe trends in healthy life expectancy (HLE) for the relevant period.
    Methods: In the absence of available long-term trends, we calculated new estimates of HLE for Scotland for the period 1995-2019, using standard HLE methodologies based on mortality and national survey data, and stratified by sex and socioeconomic deprivation.
    Results: Overall, male and female HLE increased markedly between 1995 and 2009, but then decreased by approximately 2 years between 2011 and 2019. A decline was observed for the most and least deprived groups, but this was larger for those living in the 20% most deprived areas, where the decrease was 3.5 years.
    Conclusions: Our findings are further evidence of changing levels of pre-pandemic population health in the UK. An increasing body of UK and international evidence have attributed these changes to UK Government austerity policies. There is an urgent need, therefore, to reverse cuts to social security and protect the income and health of the poorest across all of the UK.
    Language English
    Publishing date 2022-06-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 391868-3
    ISSN 1470-2738 ; 0142-467X ; 0141-7681 ; 0143-005X
    ISSN (online) 1470-2738
    ISSN 0142-467X ; 0141-7681 ; 0143-005X
    DOI 10.1136/jech-2022-219011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Correction: Inequalities in population health loss by multiple deprivation: COVID-19 and pre-pandemic all-cause disability-adjusted life years (DALYs) in Scotland.

    Wyper, Grant M A / Fletcher, Eilidh / Grant, Ian / Harding, Oliver / de Haro Moro, Maria Teresa / Stockton, Diane L / McCartney, Gerry

    International journal for equity in health

    2022  Volume 21, Issue 1, Page(s) 117

    Language English
    Publishing date 2022-08-25
    Publishing country England
    Document type Published Erratum
    ZDB-ID 2092056-8
    ISSN 1475-9276 ; 1475-9276
    ISSN (online) 1475-9276
    ISSN 1475-9276
    DOI 10.1186/s12939-022-01714-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Years of life lost methods must remain fully equitable and accountable.

    Wyper, Grant M A / Devleesschauwer, Brecht / Mathers, Colin D / McDonald, Scott A / Speybroeck, Niko

    European journal of epidemiology

    2022  Volume 37, Issue 2, Page(s) 215–216

    MeSH term(s) Humans ; Medicare ; Social Responsibility ; United States
    Language English
    Publishing date 2022-03-04
    Publishing country Netherlands
    Document type Letter ; Comment
    ZDB-ID 632614-6
    ISSN 1573-7284 ; 0393-2990
    ISSN (online) 1573-7284
    ISSN 0393-2990
    DOI 10.1007/s10654-022-00846-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Estimating the Direct Disability-Adjusted Life Years Associated With SARS-CoV-2 (COVID-19) in the Republic of Ireland: The First Full Year.

    Moran, Declan Patrick / Pires, Sara Monteiro / Wyper, Grant M A / Devleesschauwer, Brecht / Cuschieri, Sarah / Kabir, Zubair

    International journal of public health

    2022  Volume 67, Page(s) 1604699

    Abstract: Objectives: ...

    Abstract Objectives:
    MeSH term(s) COVID-19/epidemiology ; Disability-Adjusted Life Years ; Disabled Persons ; Humans ; Ireland/epidemiology ; Life Expectancy ; Quality-Adjusted Life Years ; SARS-CoV-2
    Language English
    Publishing date 2022-06-02
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2274130-6
    ISSN 1661-8564 ; 1661-8556
    ISSN (online) 1661-8564
    ISSN 1661-8556
    DOI 10.3389/ijph.2022.1604699
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Widening of inequalities in COVID-19 years of life lost from 2020 to 2021: a Scottish Burden of Disease Study.

    Wyper, Grant M A / Fletcher, Eilidh / Grant, Ian / Harding, Oliver / de Haro Moro, Maria Teresa / McCartney, Gerry / Stockton, Diane L

    Journal of epidemiology and community health

    2022  

    Abstract: Background: Previous studies have highlighted the large extent of inequality in adverse COVID-19 health outcomes. Our aim was to monitor changes in overall, and inequalities in, COVID-19 years of life lost to premature mortality (YLL) in Scotland from ... ...

    Abstract Background: Previous studies have highlighted the large extent of inequality in adverse COVID-19 health outcomes. Our aim was to monitor changes in overall, and inequalities in, COVID-19 years of life lost to premature mortality (YLL) in Scotland from 2020 and 2021.
    Methods: Cause-specific COVID-19 mortality counts were derived at age group and area deprivation level using Scottish death registrations for 2020 and 2021. YLL was estimated by multiplying mortality counts by age-conditional life expectancy from the Global Burden of Disease 2019 reference life table. Various measures of absolute and relative inequality were estimated for triangulation purposes.
    Results: There were marked inequalities in COVID-19 YLL by area deprivation in 2020, which were further exacerbated in 2021; confirmed across all measures of absolute and relative inequality. Half (51%) of COVID-19 YLL was attributable to inequalities in area deprivation in 2021, an increase from 41% in 2020.
    Conclusion: Despite a highly impactful vaccination programme in preventing mortality, COVID-19 continues to represent a substantial area of fatal population health loss for which inequalities have widened. Tackling systemic inequalities with effective interventions is required to mitigate further unjust health loss in the Scottish population from COVID-19 and other causes of ill-health and mortality.
    Language English
    Publishing date 2022-05-25
    Publishing country England
    Document type Journal Article
    ZDB-ID 391868-3
    ISSN 1470-2738 ; 0142-467X ; 0141-7681 ; 0143-005X
    ISSN (online) 1470-2738
    ISSN 0142-467X ; 0141-7681 ; 0143-005X
    DOI 10.1136/jech-2022-219090
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: A proposal for further developing fatigue-related post COVID-19 health states for burden of disease studies.

    Wyper, Grant M A / McDonald, Scott A / Haagsma, Juanita A / Devleesschauwer, Brecht / Charalampous, Periklis / Maini, Rishma / Smith, Pierre / Pires, Sara M

    Archives of public health = Archives belges de sante publique

    2023  Volume 81, Issue 1, Page(s) 193

    Abstract: Previous efforts to estimate the burden of fatigue-related symptoms due to long COVID have a very high threshold for inclusion of cases, relative to the proposed definition from the World Health Organization. In practice this means that milder cases, ... ...

    Abstract Previous efforts to estimate the burden of fatigue-related symptoms due to long COVID have a very high threshold for inclusion of cases, relative to the proposed definition from the World Health Organization. In practice this means that milder cases, that may be occurring very frequently, are not included in estimates of the burden of long COVID which will result in underestimation. A more comprehensive approach to modelling the disease burden from long COVID, in relation to fatigue, can ensure that we do not only focus on what is easiest to measure; which risks losing focus of less severe health states that may be more difficult to measure but are occurring very frequently. Our proposed approach provides a means to better understand the scale of challenge from long COVID, for consideration when preventative and mitigative action is being planned.
    Language English
    Publishing date 2023-11-02
    Publishing country England
    Document type Letter
    ZDB-ID 1117688-x
    ISSN 2049-3258 ; 0778-7367 ; 0003-9578
    ISSN (online) 2049-3258
    ISSN 0778-7367 ; 0003-9578
    DOI 10.1186/s13690-023-01212-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Estimating the direct Covid-19 disability-adjusted life years impact on the Malta population for the first full year.

    Cuschieri, Sarah / Calleja, Neville / Devleesschauwer, Brecht / Wyper, Grant M A

    BMC public health

    2021  Volume 21, Issue 1, Page(s) 1827

    Abstract: Background: Disability-adjusted life years (DALYs) combine the impact of morbidity and mortality, allowing for comprehensive comparisons of the population. The aim was to estimate the DALYs due to Covid-19 in Malta (March 2020-21) and investigate its ... ...

    Abstract Background: Disability-adjusted life years (DALYs) combine the impact of morbidity and mortality, allowing for comprehensive comparisons of the population. The aim was to estimate the DALYs due to Covid-19 in Malta (March 2020-21) and investigate its impact in relation to other causes of disease at a population level.
    Methods: Mortality and weekly hospital admission data were used to calculate DALYs, based on the European Burden of Disease Network consensus Covid-19 model. Covid-19 infection duration of 14 days was considered. Sensitivity analyses for different morbidity scenarios, including post-acute consequences were presented.
    Results: An estimated 70,421 people were infected (with and without symptoms) by Covid-19 in Malta (March 2020-1), out of which 1636 required hospitalisation and 331 deaths, contributing to 5478 DALYs. These DALYs positioned Covid-19 as the fourth leading cause of disease in Malta. Mortality contributed to 95% of DALYs, while post-acute consequences contributed to 60% of morbidity.
    Conclusions: Covid-19 over 1 year has impacted substantially the population health in Malta. Post-acute consequences are the leading morbidity factors that require urgent targeted action to ensure timely multidisciplinary care. It is recommended that DALY estimations in 2021 and beyond are calculated to assess the impact of vaccine roll-out and emergence of new variants.
    MeSH term(s) COVID-19 ; Cost of Illness ; Disabled Persons ; Humans ; Malta/epidemiology ; Quality-Adjusted Life Years ; SARS-CoV-2
    Language English
    Publishing date 2021-10-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 2041338-5
    ISSN 1471-2458 ; 1471-2458
    ISSN (online) 1471-2458
    ISSN 1471-2458
    DOI 10.1186/s12889-021-11893-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Evaluating the impact of alcohol minimum unit pricing on deaths and hospitalisations in Scotland: a controlled interrupted time series study.

    Wyper, Grant M A / Mackay, Daniel F / Fraser, Catriona / Lewsey, Jim / Robinson, Mark / Beeston, Clare / Giles, Lucie

    Lancet (London, England)

    2023  Volume 401, Issue 10385, Page(s) 1361–1370

    Abstract: Background: Since May 1, 2018, every alcoholic drink sold in Scotland has had minimum unit pricing (MUP) of £0·50 per unit. Previous studies have indicated that the introduction of this policy reduced alcohol sales by 3%. We aimed to assess whether this ...

    Abstract Background: Since May 1, 2018, every alcoholic drink sold in Scotland has had minimum unit pricing (MUP) of £0·50 per unit. Previous studies have indicated that the introduction of this policy reduced alcohol sales by 3%. We aimed to assess whether this has led to reductions in alcohol-attributable deaths and hospitalisations.
    Methods: Study outcomes, wholly attributable to alcohol consumption, were defined using routinely collected data on deaths and hospitalisations. Controlled interrupted time series regression was used to assess the legislation's impact in Scotland, and any effect modification across demographic and socioeconomic deprivation groups. The pre-intervention time series ran from Jan 1, 2012, to April 30, 2018, and for 32 months after the policy was implemented (until Dec 31, 2020). Data from England, a part of the UK where the intervention was not implemented, were used to form a control group.
    Findings: MUP in Scotland was associated with a significant 13·4% reduction (95% CI -18·4 to -8·3; p=0·0004) in deaths wholly attributable to alcohol consumption. Hospitalisations wholly attributable to alcohol consumption decreased by 4·1% (-8·3 to 0·3; p=0·064). Effects were driven by significant improvements in chronic outcomes, particularly alcoholic liver disease. Furthermore, MUP legislation was associated with a reduction in deaths and hospitalisations wholly attributable to alcohol consumption in the four most socioeconomically deprived deciles in Scotland.
    Interpretation: The implementation of MUP legislation was associated with significant reductions in deaths, and reductions in hospitalisations, wholly attributable to alcohol consumption. The greatest improvements were in the four most socioeconomically deprived deciles, indicating that the policy is positively tackling deprivation-based inequalities in alcohol-attributable health harm.
    Funding: Scottish Government.
    MeSH term(s) Humans ; Interrupted Time Series Analysis ; Alcohol Drinking/epidemiology ; Alcohol Drinking/prevention & control ; Alcoholic Beverages ; Ethanol ; Hospitalization ; Scotland/epidemiology ; Costs and Cost Analysis ; Commerce ; Time Factors
    Chemical Substances Ethanol (3K9958V90M)
    Language English
    Publishing date 2023-03-20
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 3306-6
    ISSN 1474-547X ; 0023-7507 ; 0140-6736
    ISSN (online) 1474-547X
    ISSN 0023-7507 ; 0140-6736
    DOI 10.1016/S0140-6736(23)00497-X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Corrigendum

    Declan Patrick Moran / Sara Monteiro Pires / Grant M. A. Wyper / Brecht Devleesschauwer / Sarah Cuschieri / Zubair Kabir

    International Journal of Public Health, Vol

    Estimating the Direct Disability-Adjusted Life Years Associated With SARS-CoV-2 (COVID-19) in the Republic of Ireland: The First Full Year

    2023  Volume 68

    Keywords Public aspects of medicine ; RA1-1270
    Language English
    Publishing date 2023-04-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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