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  1. Article: Generation of

    Jung, Ji Hye / Jeon, Sanghoon / Kim, Heabin / Jung, Seung-Hyun

    Development & reproduction

    2023  Volume 27, Issue 4, Page(s) 205–211

    Abstract: INTS14/VWA9, a component of the integrator complex subunits, plays a pivotal role in regulating the fate of numerous nascent RNAs transcribed by RNA polymerase II, particularly in the biogenesis of small nuclear RNAs and enhancer RNAs. Despite its ... ...

    Abstract INTS14/VWA9, a component of the integrator complex subunits, plays a pivotal role in regulating the fate of numerous nascent RNAs transcribed by RNA polymerase II, particularly in the biogenesis of small nuclear RNAs and enhancer RNAs. Despite its significance, a comprehensive mutation model for developmental research has been lacking. To address this gap, we aimed to investigate the expression patterns of
    Language English
    Publishing date 2023-12-31
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 3018107-0
    ISSN 2465-9541 ; 2465-9525
    ISSN (online) 2465-9541
    ISSN 2465-9525
    DOI 10.12717/DR.2023.27.4.205
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Higher metabolic variability increases the risk of depressive disorder in type 2 diabetes mellitus: a longitudinal nationwide cohort study.

    An, Ji Hyun / Han, Kyung-do / Jeon, Hong Jin

    Frontiers in psychiatry

    2023  Volume 14, Page(s) 1217104

    Abstract: Background and objectives: While variabilities in metabolic parameters (METv) have been linked to adverse health outcomes in type 2 DM, their association with depression is yet to be studied. This research aimed to investigate the association between ... ...

    Abstract Background and objectives: While variabilities in metabolic parameters (METv) have been linked to adverse health outcomes in type 2 DM, their association with depression is yet to be studied. This research aimed to investigate the association between METv and depressive disorder in patients with type 2 DM.
    Methods: The study involved a nationwide cohort of 1,119,631 type 2 DM patients who had undergone three or more serial health examinations between 2005 and 2012. At each visit, body mass index (BMI), fasting glucose (FG), systolic blood pressure (BP), and total cholesterol (TC) were measured and stratified into quartiles, with Q4 being the highest and Q1 the lowest. The risk of depressive disorder was evaluated using Cox proportional hazard regression models, which accounted for METs in the indexes, after adjusting for sex, income status, lifestyle habits, medical comorbidities, DM severity, and baseline levels of BMI, FG, BP, and TC.
    Results: During a mean follow-up period of 6.00 ± 2.42 years, 239,477 (21.4%) cases of type 2 DM patients developed depressive disorder. The risk of developing depressive disorder was gradually increased as the number of METv increased (HR 1.18; 95% CI 1.13, 1.23 for the group with the highest METv in all parameters compared to those with the lowest METv in all parameters). In the subgroup analysis, the risk of developing depressive disorder was 43% higher in men (HR 1.43; 95% CI 1.34, 1.51), and 31% higher in those younger than 65 years of age (HR 1.31; 95% CI 1.23, 1.39) in the group with the highest number of METv compared to the group with the lowest number of METv.
    Conclusion: In type 2 DM, higher METv was an independent risk factor for depressive disorder. This risk is notably elevated in men and individuals under the age of 65 years.
    Language English
    Publishing date 2023-07-24
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2564218-2
    ISSN 1664-0640
    ISSN 1664-0640
    DOI 10.3389/fpsyt.2023.1217104
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Stress-activated protein kinases are involved in the replication of porcine deltacoronavirus.

    Jeon, Ji Hyun / Lee, Changhee

    Virology

    2021  Volume 559, Page(s) 196–209

    Abstract: This study was conducted to examine the role of stress-activated protein kinases (SAPKs), including c-Jun ... ...

    Abstract This study was conducted to examine the role of stress-activated protein kinases (SAPKs), including c-Jun NH
    MeSH term(s) Animals ; Cell Line ; Cytokines/genetics ; Cytokines/immunology ; Deltacoronavirus/immunology ; Deltacoronavirus/physiology ; Protein Kinases/genetics ; Protein Kinases/metabolism ; Signal Transduction ; Stress, Physiological/genetics ; Stress, Physiological/physiology ; Swine ; Virus Replication
    Chemical Substances Cytokines ; Protein Kinases (EC 2.7.-)
    Language English
    Publishing date 2021-05-03
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 200425-2
    ISSN 1096-0341 ; 0042-6822
    ISSN (online) 1096-0341
    ISSN 0042-6822
    DOI 10.1016/j.virol.2021.04.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Hospital Utilization and Medication Prescriptions among Patients with Atopic Dermatitis in South Korea: A Real-World Data Analysis.

    Lee, Ji Hyun / Noh, Yunha / Choi, Ahhyung / Oh, In-Sun / Jeon, Ja-Young / Yoo, Hyun-Jeong / Shin, Ju-Young / Son, Sang Wook

    Annals of dermatology

    2023  Volume 35, Issue 5, Page(s) 374–388

    Language English
    Publishing date 2023-10-13
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 1012662-4
    ISSN 2005-3894 ; 1013-9087
    ISSN (online) 2005-3894
    ISSN 1013-9087
    DOI 10.5021/ad.22.038
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Increased metabolic variability in Korean patients with new onset bipolar disorder: a nationwide cohort study.

    Baek, Ji Hyun / Han, Kyungdo / Kim, Hyewon / Yang, Kyojin / Jeon, Hong Jin

    Frontiers in psychiatry

    2024  Volume 14, Page(s) 1256458

    Abstract: Introduction: The aim of this study was to determine associations between changes of metabolic parameters and the development of BD using nationally representative data.: Methods: We used health examination data provided by the South Korean National ... ...

    Abstract Introduction: The aim of this study was to determine associations between changes of metabolic parameters and the development of BD using nationally representative data.
    Methods: We used health examination data provided by the South Korean National Health Insurance System (NHIS) (
    Results: As the number of highly variable metabolic parameters increased, the risk for new onset depression also increased even after covariates adjustment. The associations between new onset BD and metabolic variability were greater in populations with age > 50 years. In addition, these associations remained significant after adjusting for the presence of depression prior to diagnoses of BD.
    Discussion: Our results suggest possibility of metabolic variability as an independent environmental risk factor for BD even after adjusting for the presence of metabolic syndrome.
    Language English
    Publishing date 2024-01-08
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2564218-2
    ISSN 1664-0640
    ISSN 1664-0640
    DOI 10.3389/fpsyt.2023.1256458
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Piperlongumine Induces Apoptosis and Cytoprotective Autophagy via the MAPK Signaling Pathway in Human Oral Cancer Cells.

    Choi, Eun-Young / Han, Eun-Ji / Jeon, Su-Ji / Lee, Sang-Woo / Moon, Jun-Mo / Jung, Soo-Hyun / Jung, Ji-Youn

    Biomedicines

    2023  Volume 11, Issue 9

    Abstract: Oral cancer is a malignant tumor that primarily affects areas such as the lips, tongue, buccal mucosa, salivary gland, and gingiva and has a very high malignancy. Piperlongumine (PL), isolated from long pepper ( ...

    Abstract Oral cancer is a malignant tumor that primarily affects areas such as the lips, tongue, buccal mucosa, salivary gland, and gingiva and has a very high malignancy. Piperlongumine (PL), isolated from long pepper (
    Language English
    Publishing date 2023-09-01
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2720867-9
    ISSN 2227-9059
    ISSN 2227-9059
    DOI 10.3390/biomedicines11092442
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Kaempferia parviflora rhizome extract exerts anti-obesity effect in high-fat diet-induced obese C57BL/6N mice.

    Lee, Hyun Sook / Jeon, Young Eun / Awa, Riyo / Yoshino, Susumu / Kim, Eun Ji

    Food & nutrition research

    2023  Volume 67

    Abstract: Kaempferia ... ...

    Abstract Kaempferia parviflora
    Language English
    Publishing date 2023-08-23
    Publishing country Sweden
    Document type Journal Article
    ZDB-ID 2418338-6
    ISSN 1654-661X
    ISSN 1654-661X
    DOI 10.29219/fnr.v67.9413
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: CRIF1 deficiency induces FOXP3

    Lee, Sangsin / Song, Seung Geun / Kim, Gwanghun / Kim, Sehui / Yoo, Hyun Jung / Koh, Jaemoon / Kim, Ye-Ji / Tian, Jingwen / Cho, Eunji / Choi, Youn Soo / Chang, Sunghoe / Shin, Hyun Mu / Jung, Kyeong Cheon / Kim, Ji Hoon / Kim, Tae Min / Jeon, Yoon Kyung / Kim, Hye Young / Shong, Minho / Kim, Ji Hyung /
    Chung, Doo Hyun

    Science advances

    2024  Volume 10, Issue 13, Page(s) eadj9600

    Abstract: Recently identified human ... ...

    Abstract Recently identified human FOXP3
    MeSH term(s) Humans ; Mice ; Animals ; T-Lymphocytes, Regulatory ; Ketoglutaric Acids/metabolism ; Matrix Attachment Region Binding Proteins/metabolism ; Cytokines/metabolism ; Neoplasms/genetics ; Neoplasms/metabolism ; Forkhead Transcription Factors/genetics ; Forkhead Transcription Factors/metabolism ; Mitochondrial Diseases
    Chemical Substances Ketoglutaric Acids ; Matrix Attachment Region Binding Proteins ; Cytokines ; Forkhead Transcription Factors ; SATB1 protein, human ; FOXP3 protein, human
    Language English
    Publishing date 2024-03-27
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2810933-8
    ISSN 2375-2548 ; 2375-2548
    ISSN (online) 2375-2548
    ISSN 2375-2548
    DOI 10.1126/sciadv.adj9600
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Potential of

    Ban, O-Hyun / Bang, Won Yeong / Jeon, Hyeon Ji / Jung, Young Hoon / Yang, Jungwoo / Kim, Dong Hyun

    Food science & nutrition

    2023  Volume 11, Issue 4, Page(s) 1952–1964

    Abstract: Probiotics provide important health benefits to the host by improving intestinal microbial balance and have been widely consumed as dietary supplements. In this study, we investigated ... ...

    Abstract Probiotics provide important health benefits to the host by improving intestinal microbial balance and have been widely consumed as dietary supplements. In this study, we investigated whether
    Language English
    Publishing date 2023-02-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2703010-6
    ISSN 2048-7177
    ISSN 2048-7177
    DOI 10.1002/fsn3.3230
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Erratum to: Acceleration of Mesenchymal-to-Epithelial Transition (MET) during Direct Reprogramming Using Natural Compounds.

    Seo, Ji-Hye / Jang, Si Won / Jeon, Young-Joo / Eun, So Young / Hong, Yean Ju / Do, Jeong Tae / Chae, Jung-Il / Choi, Hyun Woo

    Journal of microbiology and biotechnology

    2023  Volume 32, Issue 12, Page(s) 1632

    Language English
    Publishing date 2023-01-07
    Publishing country Korea (South)
    Document type Published Erratum
    ZDB-ID 2412195-2
    ISSN 1738-8872 ; 1738-8872
    ISSN (online) 1738-8872
    ISSN 1738-8872
    DOI 10.4014/jmb.2022.3212.1632
    Database MEDical Literature Analysis and Retrieval System OnLINE

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