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Article ; Online: Temporal Trends of Great Lakes Legacy Contaminants: Ecological and Biological Considerations Applying the Age-Trend Model.

Pagano, James J / Garner, Andrew J

Environmental science & technology

2024 Volume 58, Issue 5, Page(s) 2514–2527

Abstract: The USEPA Great Lakes Fish Monitoring and Surveillance Program (GLFMSP) has been monitoring top predator lake trout and walleye contaminant concentrations since the early 1970s. Our research revealed that select legacy contaminant groups (∑PCBs, ∑DDTs, ∑ ... ...

Abstract	The USEPA Great Lakes Fish Monitoring and Surveillance Program (GLFMSP) has been monitoring top predator lake trout and walleye contaminant concentrations since the early 1970s. Our research revealed that select legacy contaminant groups (∑PCBs, ∑DDTs, ∑chlordanes, and ∑5PBDEs) have similar
MeSH term(s)	Animals ; Water Pollutants, Chemical/analysis ; Environmental Monitoring ; Lakes ; Michigan ; Perches ; Great Lakes Region
Chemical Substances	Water Pollutants, Chemical
Language	English
Publishing date	2024-01-22
Publishing country	United States
Document type	Journal Article
ISSN	1520-5851
ISSN (online)	1520-5851
DOI	10.1021/acs.est.3c09145
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Polychlorinated Naphthalenes across the Great Lakes: Lake Trout and Walleye Concentrations, Trends, and TEQ Assessment-2004-2018.

Pagano, James J / Garner, Andrew J

Environmental science & technology

2021 Volume 55, Issue 4, Page(s) 2411–2421

Abstract: Polychlorinated naphthalenes (PCNs) were measured in lake trout and walleye over the period 2004-2018, utilizing isotope dilution techniques with high-resolution gas chromatography/high-resolution mass spectrometry to assess concentrations and toxic ... ...

Abstract	Polychlorinated naphthalenes (PCNs) were measured in lake trout and walleye over the period 2004-2018, utilizing isotope dilution techniques with high-resolution gas chromatography/high-resolution mass spectrometry to assess concentrations and toxic equivalence (TEQ). An age-trend model was applied to mitigate the effect of a changing lake trout age structure. Most Great Lakes Fish Monitoring and Surveillance Program sampling sites demonstrated significant half-life and percent decreases for lake trout total PCNs and total TEQ over the 2004-2018 period, the exceptions being Lake Erie lake trout and walleye which illustrated increasing concentrations. Great Lakes total PCN concentrations ranged between 5701 and 100 pg/g ww, whereas total PCN TEQ concentrations ranged between 8.89 and 0.13 pg-TEQ/g ww. Based on the average number of chlorines per naphthalene, we determined that the overall lake trout and walleye PCN congener distribution has significantly shifted to a lower-chlorinated composition in the Great Lakes (5.33 to 4.48 Cl/CN) and has resulted in a substantial 59.1% reduction of the overall total PCN TEQ burden. A prominent PCN concentration trend breakpoint was observed in Lake Ontario lake trout over the 2012-2016 period likely associated with hazardous waste cleanups, channel dredging, and spoils disposal in the Detroit River and western-basin of Lake Erie.
MeSH term(s)	Animals ; Environmental Monitoring ; Great Lakes Region ; Lakes ; Naphthalenes/analysis ; Ontario ; Trout ; Water Pollutants, Chemical/analysis
Chemical Substances	Naphthalenes ; Water Pollutants, Chemical
Language	English
Publishing date	2021-02-01
Publishing country	United States
Document type	Journal Article
ISSN	1520-5851
ISSN (online)	1520-5851
DOI	10.1021/acs.est.0c07507
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Article ; Online: Concentrations, toxic equivalence, and age-corrected trends of legacy organic contaminants in Lake Champlain lake trout: 2012-2018.

Pagano, James J / Garner, Andrew J

Environmental research

2020 Volume 184, Page(s) 109329

Abstract: Our study is the first comprehensive, multi-year assessment of polychlorinated biphenyls (PCBs), polybrominated diphenyl ethers (PBDEs), organochlorine pesticides (OCPs), polychlorinated naphthalenes (PCNs), polychlorinated dibenzo-p-dioxins, and ... ...

Abstract	Our study is the first comprehensive, multi-year assessment of polychlorinated biphenyls (PCBs), polybrominated diphenyl ethers (PBDEs), organochlorine pesticides (OCPs), polychlorinated naphthalenes (PCNs), polychlorinated dibenzo-p-dioxins, and polychlorinated dibenzofurans (PCDD/Fs) lake trout concentrations and trends in Lake Champlain (LC). Lake trout whole-fish, fillets, and eggs were collected over the 2012-2018 study period. Total PCB concentrations (395.7 ng/g wet weight (ww)) were the highest average concentration of any contaminant grouping reported in this study. Whole-fish lake trout modeling revealed highly significant (p < 0.05) log-linear correlations for all dioxin-like contaminants measured. Overall contaminant decreases for the 2012-2018 period ranged from 20.9% (total PCNs) to 39.3% (2378-TCDD). Contaminant decreases for total PCBs and total-5-PBDEs were 30.9% and 48.3%, respectively. Of particular significance were the measured total PBDE concentrations (74.3 ng/g ww) found in LC whole-fish lake trout. Log-linear forecasting indicates that whole-fish lake trout TEQs will be below the guidelines protective of wildlife thresholds during the periods 2035-2047 (TRG
MeSH term(s)	Animals ; Dibenzofurans ; Dibenzofurans, Polychlorinated ; Humans ; Lakes ; Polychlorinated Biphenyls/analysis ; Polychlorinated Dibenzodioxins ; Trout
Chemical Substances	Dibenzofurans ; Dibenzofurans, Polychlorinated ; Polychlorinated Dibenzodioxins ; Polychlorinated Biphenyls (DFC2HB4I0K)
Language	English
Publishing date	2020-03-04
Publishing country	Netherlands
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
ZDB-ID	205699-9
ISSN	1096-0953 ; 0013-9351
ISSN (online)	1096-0953
ISSN	0013-9351
DOI	10.1016/j.envres.2020.109329
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Zs.A 726: Show issues

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Article ; Online: Investigating the Effects of Avatarization and Interaction Techniques on Near-field Mixed Reality Interactions with Physical Components.

Venkatakrishnan, Roshan / Venkatakrishnan, Rohith / Canales, Ryan / Raveendranath, Balagopal / Pagano, Christopher C / Robb, Andrew C / Lin, Wen-Chieh / Babu, Sabarish V

IEEE transactions on visualization and computer graphics

2024 Volume PP

Abstract: Mixed reality (MR) interactions feature users interacting with a combination of virtual and physical components. Inspired by research investigating aspects associated with near-field interactions in augmented and virtual reality (AR & VR), we ... ...

Abstract	Mixed reality (MR) interactions feature users interacting with a combination of virtual and physical components. Inspired by research investigating aspects associated with near-field interactions in augmented and virtual reality (AR & VR), we investigated how avatarization, the physicality of the interacting components, and the interaction technique used to manipulate a virtual object affected performance and perceptions of user experience in a mixed reality fundamentals of laparoscopic peg-transfer task wherein users had to transfer a virtual ring from one peg to another for a number of trials. We employed a 3 (Physicality of pegs) X 3 (Augmented Avatar Representation) X 2 (Interaction Technique) multi-factorial design, manipulating the physicality of the pegs as a between-subjects factor, the type of augmented self-avatar representation, and the type of interaction technique used for object-manipulation as within-subjects factors. Results indicated that users were significantly more accurate when the pegs were virtual rather than physical because of the increased salience of the task-relevant visual information. From an avatar perspective, providing users with a reach envelope-extending representation, though useful, was found to worsen performance, while co-located avatarization significantly improved performance. Choosing an interaction technique to manipulate objects depends on whether accuracy or efficiency is a priority. Finally, the relationship between the avatar representation and interaction technique dictates just how usable mixed reality interactions are deemed to be.
Language	English
Publishing date	2024-03-04
Publishing country	United States
Document type	Journal Article
ISSN	1941-0506
ISSN (online)	1941-0506
DOI	10.1109/TVCG.2024.3372050
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Article ; Online: Objects May Be Farther Than They Appear: Depth Compression Diminishes Over Time with Repeated Calibration in Virtual Reality.

Kohm, Kristopher / Babu, Sabarish V / Pagano, Christopher / Robb, Andrew

IEEE transactions on visualization and computer graphics

2022 Volume 28, Issue 11, Page(s) 3907–3916

Abstract: Prior research in depth perception and perceptuo-motor calibration have primarily focused on participants completing experiments in single sessions and therefore do not empirically evaluate changes over time. Further, these studies do not typically take ... ...

Abstract	Prior research in depth perception and perceptuo-motor calibration have primarily focused on participants completing experiments in single sessions and therefore do not empirically evaluate changes over time. Further, these studies do not typically take into account the amount of experience that the participants have in virtual reality (VR) prior to participation, the role of experience during participation, or calibration that may occur throughout the experiment session. In this contribution, we conducted a novel empirical evaluation of how calibration affects perception-action coordination over time. We recruited novice VR users and they completed eight sessions of a depth perception reaching experiment over the course of 12 weeks. During these experiments, we examined how participants' ability to estimate depth in a virtual environment changed as they gradually gained experience. While previous literature has shown that participants tend to underestimate distances, we found that this underestimation diminished over time as they gained experience in the virtual environment. Our study highlights the need for carrying out VR studies over time and the influence that longitudinal calibration can have on spatial perception in long-term VR experiences.
MeSH term(s)	Humans ; Calibration ; Computer Graphics ; Virtual Reality
Language	English
Publishing date	2022-10-21
Publishing country	United States
Document type	Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
ISSN	1941-0506
ISSN (online)	1941-0506
DOI	10.1109/TVCG.2022.3203112
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Article ; Online: Trends of polychlorinated dioxins, polychlorinated furans, and dioxin-like polychlorinated biphenyls in Chinook and Coho salmonid eggs from a Great Lakes tributary.

Garner, Andrew J / Pagano, James J

Environmental pollution (Barking, Essex : 1987)

2019 Volume 247, Page(s) 1039–1045

Abstract: Eggs from mature Chinook (Oncorhynchus tshawytscha) and Coho (Oncorhynchus kisutch) salmon were collected between 2004 and 2014 from the Salmon River fish hatchery in Altmar, New York. The egg samples were analyzed for seventeen polychlorinated ... ...

Abstract	Eggs from mature Chinook (Oncorhynchus tshawytscha) and Coho (Oncorhynchus kisutch) salmon were collected between 2004 and 2014 from the Salmon River fish hatchery in Altmar, New York. The egg samples were analyzed for seventeen polychlorinated dibenzodioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs), as well as four dioxin-like polychlorinated biphenyls (DL-PCBs) using USEPA methods 1613 and 1668. Salmonid eggs were chosen as a tissue of interest since salmon feed at all trophic levels of the food web as they grow, and spawn in a narrow range of ages providing consistent, representative, and temporal samples of contaminant exposure. First-order decay models indicate decreasing trends for all select contaminants in both species, expressed by a toxic equivalence (TEQ) half-life (t
MeSH term(s)	Animals ; Dioxins/analysis ; Eggs/analysis ; Environmental Monitoring ; Furans/analysis ; Great Lakes Region ; Lakes/chemistry ; New York ; Oncorhynchus/growth & development ; Ontario ; Polychlorinated Biphenyls/analysis ; Rivers/chemistry ; Seafood/analysis
Chemical Substances	Dioxins ; Furans ; Polychlorinated Biphenyls (DFC2HB4I0K)
Language	English
Publishing date	2019-02-05
Publishing country	England
Document type	Journal Article
ZDB-ID	280652-6
ISSN	1873-6424 ; 0013-9327 ; 0269-7491
ISSN (online)	1873-6424
ISSN	0013-9327 ; 0269-7491
DOI	10.1016/j.envpol.2019.01.117
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Zs.A 2599: Show issues

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ab Jg. 2022: Lesesaal (EG)

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Article ; Online: Systematic review for the serological testing for cold agglutinins: The BEST collaborative study.

Jalink, Marit / Yan, Matthew T S / Cohn, Claudia S / Eichbaum, Quentin G / Fung, Mark K / Lu, Wen / Murphy, Michael F / Pagano, Monica B / Stanworth, Simon J / Shih, Andrew W

Transfusion

2024

Language	English
Publishing date	2024-04-20
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	208417-x
ISSN	1537-2995 ; 0041-1132
ISSN (online)	1537-2995
ISSN	0041-1132
DOI	10.1111/trf.17842
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Zs.A 284: Show issues

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Article ; Online: Evaluation of interstitial lung disease: An algorithmic review using ILD-RADS.

Pagano, Andrew M / Vu, Tam / Berkowitz, Eugene A / Little, Brent P / Chung, Michael / Bernheim, Adam

Clinical imaging

2022 Volume 88, Page(s) 45–52

Abstract: Interstitial lung diseases (ILDs) may present a diagnostic dilemma due to their many classifications and overlapping imaging findings. In this review, we present an algorithmic approach for assessing ILDs based on identifying and understanding key ... ...

Abstract	Interstitial lung diseases (ILDs) may present a diagnostic dilemma due to their many classifications and overlapping imaging findings. In this review, we present an algorithmic approach for assessing ILDs based on identifying and understanding key imaging features to aid in narrowing a differential diagnosis or reaching a specific diagnosis. We use the recently introduced Interstitial Lung Disease Reporting And Data System (ILD-RADS) as a framework for our discussion.
MeSH term(s)	Diagnosis, Differential ; Humans ; Lung/diagnostic imaging ; Lung Diseases, Interstitial/diagnostic imaging
Language	English
Publishing date	2022-05-04
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	1028123-x
ISSN	1873-4499 ; 0899-7071
ISSN (online)	1873-4499
ISSN	0899-7071
DOI	10.1016/j.clinimag.2022.04.019
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Zs.A 1469: Show issues

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Article ; Online: Can I Squeeze Through? Effects of Self-Avatars and Calibration in a Person-Plus-Virtual-Object System on Perceived Lateral Passability in VR.

Bhargava, Ayush / Venkatakrishnan, Rohith / Venkatakrishnan, Roshan / Lucaites, Kathryn / Solini, Hannah / Robb, Andrew C / Pagano, Christopher C / Babu, Sabarish V

IEEE transactions on visualization and computer graphics

2023 Volume PP

Abstract: With the popularity of Virtual Reality (VR) on the rise, creators from a variety of fields are building increasingly complex experiences that allow users to express themselves more naturally. Self-avatars and object interaction in virtual worlds are at ... ...

Abstract	With the popularity of Virtual Reality (VR) on the rise, creators from a variety of fields are building increasingly complex experiences that allow users to express themselves more naturally. Self-avatars and object interaction in virtual worlds are at the heart of these experiences. However, these give rise to several perception based challenges that have been the focus of research in recent years. One area that garners most interest is understanding the effects of self-avatars and object interaction on action capabilities or affordances in VR. Affordances have been shown to be influenced by the anthropometric and anthropomorphic properties of the self-avatar embodied. However, self-avatars cannot fully represent real world interaction and fail to provide information about the dynamic properties of surfaces in the environment. For example, pressing against a board to feel its rigidity. This lack of accurate dynamic information can be further amplified when interacting with virtual handheld objects as the weight and inertial feedback associated with them is often mismatched. To investigate this phenomenon, we looked at how the absence of dynamic surface properties affect lateral passability judgments when carrying virtual handheld objects in the presence or absence of gender matched body-scaled self-avatars. Results suggest that participants can calibrate to the missing dynamic information in the presence of self-avatars to make lateral passability judgments, but rely on their internal body schema of a compressed physical body depth in the absence of self-avatars.
Language	English
Publishing date	2023-02-22
Publishing country	United States
Document type	Journal Article
ISSN	1941-0506
ISSN (online)	1941-0506
DOI	10.1109/TVCG.2023.3247067
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Article ; Online: Give Me a Hand: Improving the Effectiveness of Near-field Augmented Reality Interactions By Avatarizing Users' End Effectors.

Venkatakrishnan, Roshan / Venkatakrishnan, Rohith / Raveendranath, Balagopal / Pagano, Christopher C / Robb, Andrew C / Lin, Wen-Chieh / Babu, Sabarish V

IEEE transactions on visualization and computer graphics

2023 Volume PP

Abstract: Inspired by previous works showing promise for AR self-avatarization - providing users with an augmented self avatar, we investigated whether avatarizing users' end-effectors (hands) improved their interaction performance on a near-field, obstacle ... ...

Abstract	Inspired by previous works showing promise for AR self-avatarization - providing users with an augmented self avatar, we investigated whether avatarizing users' end-effectors (hands) improved their interaction performance on a near-field, obstacle avoidance, object retrieval task wherein users were tasked with retrieving a target object from a field of non-target obstacles for a number of trials. We employed a 3 (Augmented hand representation) X 2 (density of obstacles) X 2 (size of obstacles) X 2 (virtual light intensity) multi-factorial design, manipulating the presence/absence and anthropomorphic fidelity of augmented self-avatars overlaid on the user's real hands, as a between subjects factor across three experimental conditions: (1) No-Augmented Avatar (using only real hands); (2) Iconic-Augmented Avatar; (3) Realistic Augmented Avatar. Results indicated that self-avatarization improved interaction performance and was perceived as more usable regardless of the anthropomorphic fidelity of avatar. We also found that the virtual light intensity used in illuminating holograms affects how visible one's real hands are. Overall, our findings seem to indicate that interaction performance may improve when users are provided with a visual representation of the AR system's interacting layer in the form of an augmented self-avatar.
Language	English
Publishing date	2023-02-22
Publishing country	United States
Document type	Journal Article
ISSN	1941-0506
ISSN (online)	1941-0506
DOI	10.1109/TVCG.2023.3247105
Database	MEDical Literature Analysis and Retrieval System OnLINE

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