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Article ; Online: Pedigree diversity and implications for genetic selection of Katahdin sheep.

Nilson, Sara M / Burke, Joan M / Murdoch, Brenda M / Morgan, James L M / Lewis, Ronald M

Journal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und Zuchtungsbiologie

2023 Volume 141, Issue 3, Page(s) 304–316

Abstract: The Katahdin hair breed gained popularity in the United States as low input and prolific, with a propensity to exhibit parasite resistance. With the introduction of genomically enhanced estimated breeding values (GEBV) to the Katahdin genetic evaluation, ...

Abstract	The Katahdin hair breed gained popularity in the United States as low input and prolific, with a propensity to exhibit parasite resistance. With the introduction of genomically enhanced estimated breeding values (GEBV) to the Katahdin genetic evaluation, defining the diversity present in the breed is pertinent. Utilizing pedigree records (n = 92,030) from 1984 to 2019 from the National Sheep Improvement Program, our objectives were to (i) estimate the completeness and quality of the pedigree, (ii) calculate diversity statistics for the whole pedigree and relevant reference subpopulations and (iii) assess the impact of current diversity on genomic selection. Reference 1 was Katahdins born from 2017 to 2019 (n = 23,494), while reference 2 was a subset with at least three generations of Katahdin ancestry (n = 9327). The completeness of the whole pedigree, and the pedigrees of reference 1 and reference 2, were above 50% through the fourth, fifth and seventh generation of ancestors, respectively. Effective population size (N
MeSH term(s)	Sheep/genetics ; Animals ; Genetic Variation ; Pedigree ; Inbreeding ; Population Density ; Selection, Genetic
Language	English
Publishing date	2023-12-18
Publishing country	Germany
Document type	Journal Article
ZDB-ID	631363-2
ISSN	1439-0388 ; 0044-3581 ; 0931-2668 ; 1742-4488
ISSN (online)	1439-0388
ISSN	0044-3581 ; 0931-2668 ; 1742-4488
DOI	10.1111/jbg.12842
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Reducing transmission of COVID-19 using a continuous negative pressure operative field barrier during oral maxillofacial surgery.

Gonzalez-Ciccarelli, Luis F / Nilson, James / Oreadi, Daniel / Fakitsas, Dimitrios / Sekhar, Pavan / Quraishi, Sadeq A

Oral and maxillofacial surgery cases

2020 Volume 6, Issue 3, Page(s) 100160

Abstract: Oral and maxillofacial surgery in patients with suspected or confirmed COVID-19, presents a high risk of exposure and cross contamination to the operative room personnel. We designed, simulated and implemented a continue negative pressure operative field ...

Abstract	Oral and maxillofacial surgery in patients with suspected or confirmed COVID-19, presents a high risk of exposure and cross contamination to the operative room personnel. We designed, simulated and implemented a continue negative pressure operative field barrier to provide an additional layer of protection, using standard equipment readily available in most operative rooms during oral and maxillofacial procedures.
Keywords	covid19
Language	English
Publishing date	2020-05-30
Publishing country	United States
Document type	Case Reports
ZDB-ID	2834864-3
ISSN	2214-5419 ; 2214-5419
ISSN (online)	2214-5419
ISSN	2214-5419
DOI	10.1016/j.omsc.2020.100160
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Article ; Online: Portable negative pressure environment to protect staff during aerosol-generating procedures in patients with COVID-19.

Nilson, James / Bugaev, Nikolay / Sekhar, Pavan / Hojman, Haracio / Gonzalez-Ciccarelli, Luis / Quraishi, Sadeq A

BMJ open respiratory research

2020 Volume 7, Issue 1

Abstract: Patients with COVID-19 often need therapeutic interventions that are considered high aerosol-generating procedures. These are either being performed by healthcare providers with potentially inadequate personal protective equipment or the procedures are ... ...

Abstract	Patients with COVID-19 often need therapeutic interventions that are considered high aerosol-generating procedures. These are either being performed by healthcare providers with potentially inadequate personal protective equipment or the procedures are being delayed until patients clear their viral load. Both scenarios are suboptimal. We present a simple, cost-effective method of creating a portable negative pressure environment using equipment that is found in most hospitals to better protect healthcare providers and to facilitate more timely care for patients with COVID-19.
MeSH term(s)	Aerosols ; Betacoronavirus ; COVID-19 ; Coronavirus Infections/prevention & control ; Humans ; Occupational Exposure/prevention & control ; Operating Rooms/methods ; Pandemics/prevention & control ; Pneumonia, Viral/prevention & control ; Pressure ; SARS-CoV-2 ; Suction ; Surgical Drapes
Chemical Substances	Aerosols
Keywords	covid19
Language	English
Publishing date	2020-09-23
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	2736454-9
ISSN	2052-4439 ; 2052-4439
ISSN (online)	2052-4439
ISSN	2052-4439
DOI	10.1136/bmjresp-2020-000653
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Article ; Online: Analysis of local extracellular matrix identifies different aetiologies behind bicuspid and tricuspid aortic valve degeneration and suggests therapies.

Beusch, Christian M / Simonson, Oscar E / Wedin, Johan O / Sabatier, Pierre / Felldin, Ulrika / Kadekar, Sandeep / Österholm, Cecilia / Végvári, Ákos / Zubarev, Roman A / Fromell, Karin / Nilson, Bo / James, Stefan / Ståhle, Elisabeth / Grinnemo, Karl-Henrik / Rodin, Sergey

Cellular and molecular life sciences : CMLS

2023 Volume 80, Issue 9, Page(s) 268

Abstract: Aortic valve degeneration (AVD) is a life-threatening condition that has no medical treatment and lacks individual therapies. Although extensively studied with standard approaches, aetiologies behind AVD are unclear. We compared abundances of ... ...

Abstract	Aortic valve degeneration (AVD) is a life-threatening condition that has no medical treatment and lacks individual therapies. Although extensively studied with standard approaches, aetiologies behind AVD are unclear. We compared abundances of extracellular matrix (ECM) proteins from excised valve tissues of 88 patients with isolated AVD of normal tricuspid (TAV) and congenital bicuspid aortic valves (BAV), quantified more than 1400 proteins per ECM sample by mass spectrometry, and demonstrated that local ECM preserves molecular cues of the pathophysiological processes. The BAV ECM showed enrichment with fibrosis markers, namely Tenascin C, Osteoprotegerin, and Thrombospondin-2. The abnormal physical stress on BAV may cause a mechanical injury leading to a continuous Tenascin C-driven presence of myofibroblasts and persistent fibrosis. The TAV ECM exhibited enrichment with Annexin A3 (p = 1.1 × 10
MeSH term(s)	Humans ; Aortic Valve ; Tenascin ; Proteomics ; Extracellular Matrix ; Aorta
Chemical Substances	Tenascin
Language	English
Publishing date	2023-08-26
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	1358415-7
ISSN	1420-9071 ; 1420-682X
ISSN (online)	1420-9071
ISSN	1420-682X
DOI	10.1007/s00018-023-04926-1
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Nutrition assessment and MASH severity in children using the Healthy Eating Index.

Jain, Ajay Kumar / Buchannan, Paula / Yates, Katherine P / Belt, Patricia / Schwimmer, Jeffrey B / Rosenthal, Philip / Murray, Karen F / Molleston, Jean P / Scheimann, Ann / Xanthakos, Stavra A / Behling, Cynthia A / Hertel, Paula / Nilson, Jamie / Neuschwander-Tetri, Brent A / Tonascia, James / Vos, Miriam B

Hepatology communications

2023 Volume 7, Issue 12

Abstract: Background: Pediatric metabolic-associated fatty liver disease (MAFLD) is a global health problem, with lifestyle modification as its major therapeutic strategy. Rigorous characterization of dietary content on MAFLD in children is lacking. We ... ...

Abstract	Background: Pediatric metabolic-associated fatty liver disease (MAFLD) is a global health problem, with lifestyle modification as its major therapeutic strategy. Rigorous characterization of dietary content on MAFLD in children is lacking. We hypothesized an objectively measured healthier diet would positively modulate MAFLD. Methods: Diet was assessed using the Nutrition Data System for Research in children enrolled from 10 tertiary clinical centers to determine the Healthy Eating Index (HEI, 0-100) and individual food components. Results: In all, 119 children were included (13.3 ± 2.7 y), 80 (67%) male, 67 (18%) White, and 90 (76%) Hispanic, with an average body mass index Z-score of 2.2 ± 0.5. Diet was classified as low HEI < 47.94 (n = 39), mid HEI ≥ 47.94 and < 58.89 (n = 41), or high HEI ≥ 58.89 (n=39). Children with high HEI (healthier diet) had lower body weight (p = 0.005) and more favorable lipids. Mean serum triglycerides for low, mid, and high HEI were 163, 148, and 120 mg/dL, respectively; p = 0.04 mid versus high, p = 0.01 low versus high. Mean HDL was 38, 41 and 43 mg/dL; p = 0.02 low vs high. Less severe steatosis was noted with added sugar ≤ 10% of calories (p = 0.03). Higher lobular inflammation is associated with a higher percentage of calories from fat (OR (95% CI) = 0.95 (0.91-1.00), p = 0.04). Conclusions: In children with MAFLD, high HEI is associated with lower body weight and more favorable lipids, while added sugar and fat intake has individual histologic features. Differential consumption of major dietary components may modify both metabolic risk factors and histologic liver injury, highlighting the importance of objective diet assessments in children with MAFLD.
MeSH term(s)	Humans ; Male ; Child ; Female ; Diet, Healthy ; Nutrition Assessment ; Lipids ; Sugars ; Body Weight
Chemical Substances	Lipids ; Sugars
Language	English
Publishing date	2023-12-07
Publishing country	United States
Document type	Journal Article
ISSN	2471-254X
ISSN (online)	2471-254X
DOI	10.1097/HC9.0000000000000320
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Book ; Online: Modularis

Herrin, Baker / Close, Victoria / Berner, Nathan / Herbert, Joshua / Reussow, Ethan / James, Ryan / Woodward, Cale / Mindlin, Jared / Paez, Sebastian / Bretas, Nilson / Shin, Jane

Modular Underwater Robot for Rapid Development and Validation of Autonomous Systems

2024

Abstract: Autonomous underwater robots typically require higher cost and time for demonstrations compared to other domains due to the complexity of the environment. Due to the limited capacity and payload flexibility, it is challenging to find off-the-shelf ... ...

Abstract	Autonomous underwater robots typically require higher cost and time for demonstrations compared to other domains due to the complexity of the environment. Due to the limited capacity and payload flexibility, it is challenging to find off-the-shelf underwater robots that are affordable, customizable, and subject to environmental variability. Custom-built underwater robots may be necessary for specialized applications or missions, but the process can be more costly and time-consuming than purchasing an off-the-shelf autonomous underwater vehicle (AUV). To address these challenges, we propose a modular underwater robot, Modularis, that can serve as an open-source testbed system. Our proposed system expedites the testing of perception, planning, and control algorithms. Comment: 7 pages, 13 figures, presented at OCEANS 2023
Keywords	Computer Science - Robotics
Publishing date	2024-01-11
Publishing country	us
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Novel Tracheostomy and Percutaneous Endoscopic Gastrostomy Technique for COVID-19 Patients in a Nonnegative Pressure Environment.

Tian, Tina / Bugaev, Nikolay / Johnson, Benjamin P / Mahoney, Eric / Nilson, James / Sekhar, Pavan / Hojman, Horacio

The American surgeon

2020 Volume 89, Issue 3, Page(s) 493–495

MeSH term(s)	Humans ; Tracheostomy/methods ; Gastrostomy/methods ; COVID-19 ; Enteral Nutrition ; Gastroscopy
Language	English
Publishing date	2020-12-07
Publishing country	United States
Document type	Journal Article
ZDB-ID	202465-2
ISSN	1555-9823 ; 0003-1348
ISSN (online)	1555-9823
ISSN	0003-1348
DOI	10.1177/0003134820960072
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Article ; Online: Portable negative pressure environment to protect staff during aerosol-generating procedures in patients with COVID-19

Nikolay Bugaev / Sadeq A Quraishi / James Nilson / Pavan Sekhar / Haracio Hojman / Luis Gonzalez-Ciccarelli

BMJ Open Respiratory Research, Vol 7, Iss

2020 Volume 1

Abstract	Patients with COVID-19 often need therapeutic interventions that are considered high aerosol-generating procedures. These are either being performed by healthcare providers with potentially inadequate personal protective equipment or the procedures are being delayed until patients clear their viral load. Both scenarios are suboptimal. We present a simple, cost-effective method of creating a portable negative pressure environment using equipment that is found in most hospitals to better protect healthcare providers and to facilitate more timely care for patients with COVID-19.
Keywords	Medicine ; R ; Diseases of the respiratory system ; RC705-779
Language	English
Publishing date	2020-05-01T00:00:00Z
Publisher	BMJ Publishing Group
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Continuous Negative Pressure Operative Field Barrier for Combined Open Tracheostomy and Percutaneous Endoscopic Gastrostomy Tube Placement During Coronavirus Disease 2019.

Gonzalez-Ciccarelli, Luis F / Nilson, James / Hojman, Horacio M / Sekhar, Pavan / Velez, Madeline / Quraishi, Sadeq A

A&A practice

2020 Volume 14, Issue 14, Page(s) e01371

Abstract: Respiratory failure in coronavirus disease 2019 (COVID-19) patients with prolonged endotracheal intubation may require a tracheostomy and percutaneous endoscopic gastrostomy (PEG) tube placement to facilitate recovery. Both techniques are considered high- ...

Abstract	Respiratory failure in coronavirus disease 2019 (COVID-19) patients with prolonged endotracheal intubation may require a tracheostomy and percutaneous endoscopic gastrostomy (PEG) tube placement to facilitate recovery. Both techniques are considered high-risk aerosol-generating procedures and present a heightened risk of exposure to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) for operating room personnel. We designed, simulated, and implemented a portable, continuous negative pressure, operative field barrier system using standard equipment available in hospitals to enhance health care provider safety during high-risk aerosol-generating procedures.
MeSH term(s)	Aerosols ; Air Pressure ; COVID-19/complications ; COVID-19/prevention & control ; COVID-19/transmission ; Endoscopy, Gastrointestinal/methods ; Enteral Nutrition ; Filtration ; Gastrostomy/methods ; Humans ; Infectious Disease Transmission, Patient-to-Professional/prevention & control ; Male ; Middle Aged ; Minimally Invasive Surgical Procedures/methods ; Operating Rooms ; Patient Isolation ; Tracheostomy/methods
Chemical Substances	Aerosols
Language	English
Publishing date	2020-12-21
Publishing country	United States
Document type	Case Reports ; Journal Article
ISSN	2575-3126
ISSN (online)	2575-3126
DOI	10.1213/XAA.0000000000001371
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: From The Flame and the Flower to Fifty Shades of Grey

Maria Nilson

Akademisk Kvarter, Iss

2013 Volume 7

Abstract: ... Nilson focuses on how James uses well known and established romance traits from, for example ... in both how James describes her protagonists and in howthe relationship between them is portrayed. Nilson ... E.L. James’s Fifty Shades trilogy has become a huge success and soldmillions of copies. The novels ...

Abstract	E.L. James’s Fifty Shades trilogy has become a huge success and soldmillions of copies. The novels’ mix of romance and erotica has beendescribed as something new. Reading these books mainly as romance, Nilson focuses on how James uses well known and established romance traits from, for example, the so-called “bodice-ripper” novel and chick lit, in order to create a hybrid. These traits arevisible in both how James describes her protagonists and in howthe relationship between them is portrayed. Nilson argues that theFifty Shades trilogy is, rather than a new kind of romance, a compilation of well-established traits.
Keywords	romance ; “the bodice-ripper,” chick lit ; popular fiction ; desire ; sex ; History of scholarship and learning. The humanities ; AZ20-999
Language	Danish
Publishing date	2013-12-01T00:00:00Z
Publisher	Aalborg University Press
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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