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  1. Article ; Online: Revisión de literatura sobre la marca y la sostenibilidad

    Vanesa Sanguino García / Carlos Mario Berrío Meneses / Diego Alejandro Diez Arias

    Economia Creativa, Iss

    2023  Volume 18

    Abstract: La sostenibilidad es el escenario actual donde convergen diferentes actores: sociedad civil, empresas y gobiernos articulan esfuerzos para responder a los Objetivos de Desarrollo Sostenible y así ayudar a reducir los principales desafíos globales como la ...

    Abstract La sostenibilidad es el escenario actual donde convergen diferentes actores: sociedad civil, empresas y gobiernos articulan esfuerzos para responder a los Objetivos de Desarrollo Sostenible y así ayudar a reducir los principales desafíos globales como la pobreza y los desastres ambientales. La marca como dinamizador social no es ajena a este compromiso. El propósito de este trabajo es identificar las aproximaciones teóricas sobre la marca y la sostenibilidad; para esto se estableció un protocolo de revisión descriptiva de literatura utilizando la ecuación TITLE-ABS-KEY ("sustainability AND branding"). Los documentos fueron obtenidos en el sistema de bases de datos Scopus, EBSCO, JSTOR y ScienceDirect, en un periodo de 2009 a 2022, como resultado se obtuvieron 333 referencias. Se organizaron bajo la metodología DESLIZAR de Maeda (2006), dejando un total de 88 artículos. Los resultados develan un limitado constructo teórico sobre la marca y la sostenibilidad, convirtiéndose en una oportunidad para el aporte conceptual en futuras investigaciones. Videoabstract Te invitamos a ver la explicacion del artículo en palabras del autor. Da click aquí para abrir el reproductor de video.
    Keywords Marca ; Sostenibilidad ; Revisión de literatura ; Economic theory. Demography ; HB1-3840 ; Social sciences (General) ; H1-99
    Language English
    Publishing date 2023-07-01T00:00:00Z
    Publisher Centro de Diseño, Cine y Television
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Gunshot-related giant brachial artery pseudoaneurysm: Case report.

    Berrio-Caicedo, Jhon Jairo / Arroyave, Cristhian David / Burgos-Rueda, Hugo Alejandro

    Trauma case reports

    2022  Volume 38, Page(s) 100610

    Abstract: Pseudoaneurysms are late and rare complications in the upper limbs due to penetrating vascular trauma. Although endovascular management is offered as the ideal approach, there are some anatomical conditions to consider surgical treatment. An 18-year-old ... ...

    Abstract Pseudoaneurysms are late and rare complications in the upper limbs due to penetrating vascular trauma. Although endovascular management is offered as the ideal approach, there are some anatomical conditions to consider surgical treatment. An 18-year-old patient was admitted into our hospital two months later after suffering a single gunshot on the left arm. The arteriography showed loss of most of the branchial artery (BA) course, which was replaced by an unusual 14 ∗ 10 cm pseudoaneurysm. The increasing deformity within the anterior compartment of the arm generated neuropathic and ischemic symptoms (NIS) that were resolved after the drainage and reconstruction of BA. An autologous, ipsilateral basilic vein (BV) graft was used for this purpose. After 26 months, the normal hemodynamic conditions of the treated limb allowed the patient to remain asymptomatic.
    Language English
    Publishing date 2022-01-28
    Publishing country Netherlands
    Document type Case Reports
    ZDB-ID 2835433-3
    ISSN 2352-6440 ; 2352-6440
    ISSN (online) 2352-6440
    ISSN 2352-6440
    DOI 10.1016/j.tcr.2022.100610
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Identifying branch-specific positive selection throughout the regulatory genome using an appropriate proxy neutral.

    Berrio, Alejandro / Haygood, Ralph / Wray, Gregory A

    BMC genomics

    2020  Volume 21, Issue 1, Page(s) 359

    Abstract: Background: Adaptive changes in cis-regulatory elements are an essential component of evolution by natural selection. Identifying adaptive and functional noncoding DNA elements throughout the genome is therefore crucial for understanding the ... ...

    Abstract Background: Adaptive changes in cis-regulatory elements are an essential component of evolution by natural selection. Identifying adaptive and functional noncoding DNA elements throughout the genome is therefore crucial for understanding the relationship between phenotype and genotype.
    Results: We used ENCODE annotations to identify appropriate proxy neutral sequences and demonstrate that the conservativeness of the test can be modulated during the filtration of reference alignments. We applied the method to noncoding Human Accelerated Elements as well as open chromatin elements previously identified in 125 human tissues and cell lines to demonstrate its utility. Then, we evaluated the impact of query region length, proxy neutral sequence length, and branch count on test sensitivity and specificity. We found that the length of the query alignment can vary between 150 bp and 1 kb without affecting the estimation of selection, while for the reference alignment, we found that a length of 3 kb is adequate for proper testing. We also simulated sequence alignments under different classes of evolution and validated our ability to distinguish positive selection from relaxation of constraint and neutral evolution. Finally, we re-confirmed that a quarter of all non-coding Human Accelerated Elements are evolving by positive selection.
    Conclusion: Here, we introduce a method we called adaptiPhy, which adds significant improvements to our earlier method that tests for branch-specific directional selection in noncoding sequences. The motivation for these improvements is to provide a more sensitive and better targeted characterization of directional selection and neutral evolution across the genome.
    MeSH term(s) Animals ; Evolution, Molecular ; Genetic Drift ; Genome/genetics ; Genomics/methods ; Humans ; Models, Genetic ; Regulatory Sequences, Nucleic Acid/genetics ; Selection, Genetic ; Sequence Alignment ; Sequence Analysis, DNA
    Language English
    Publishing date 2020-05-13
    Publishing country England
    Document type Journal Article
    ZDB-ID 2041499-7
    ISSN 1471-2164 ; 1471-2164
    ISSN (online) 1471-2164
    ISSN 1471-2164
    DOI 10.1186/s12864-020-6752-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Positive selection within the genomes of SARS-CoV-2 and other Coronaviruses independent of impact on protein function.

    Berrio, Alejandro / Gartner, Valerie / Wray, Gregory A

    PeerJ

    2020  Volume 8, Page(s) e10234

    Abstract: Background: The emergence of a novel coronavirus (SARS-CoV-2) associated with severe acute respiratory disease (COVID-19) has prompted efforts to understand the genetic basis for its unique characteristics and its jump from non-primate hosts to humans. ... ...

    Abstract Background: The emergence of a novel coronavirus (SARS-CoV-2) associated with severe acute respiratory disease (COVID-19) has prompted efforts to understand the genetic basis for its unique characteristics and its jump from non-primate hosts to humans. Tests for positive selection can identify apparently nonrandom patterns of mutation accumulation within genomes, highlighting regions where molecular function may have changed during the origin of a species. Several recent studies of the SARS-CoV-2 genome have identified signals of conservation and positive selection within the gene encoding Spike protein based on the ratio of synonymous to nonsynonymous substitution. Such tests cannot, however, detect changes in the function of RNA molecules.
    Methods: Here we apply a test for branch-specific oversubstitution of mutations within narrow windows of the genome without reference to the genetic code.
    Results: We recapitulate the finding that the gene encoding Spike protein has been a target of both purifying and positive selection. In addition, we find other likely targets of positive selection within the genome of SARS-CoV-2, specifically within the genes encoding Nsp4 and Nsp16. Homology-directed modeling indicates no change in either Nsp4 or Nsp16 protein structure relative to the most recent common ancestor. These SARS-CoV-2-specific mutations may affect molecular processes mediated by the positive or negative RNA molecules, including transcription, translation, RNA stability, and evasion of the host innate immune system. Our results highlight the importance of considering mutations in viral genomes not only from the perspective of their impact on protein structure, but also how they may impact other molecular processes critical to the viral life cycle.
    Keywords covid19
    Language English
    Publishing date 2020-10-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2703241-3
    ISSN 2167-8359
    ISSN 2167-8359
    DOI 10.7717/peerj.10234
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Human tissue-resident peritoneal macrophages reveal resistance towards oxidative cell stress induced by non-invasive physical plasma.

    Schultze-Rhonhof, Laura / Marzi, Julia / Carvajal Berrio, Daniel Alejandro / Holl, Myriam / Braun, Theresa / Schäfer-Ruoff, Felix / Andress, Jürgen / Bachmann, Cornelia / Templin, Markus / Brucker, Sara Y / Schenke-Layland, Katja / Weiss, Martin

    Frontiers in immunology

    2024  Volume 15, Page(s) 1357340

    Abstract: In the context of multimodal treatments for abdominal cancer, including procedures such as cytoreductive surgery and intraperitoneal chemotherapy, recurrence rates remain high, and long-term survival benefits are uncertain due to post-operative ... ...

    Abstract In the context of multimodal treatments for abdominal cancer, including procedures such as cytoreductive surgery and intraperitoneal chemotherapy, recurrence rates remain high, and long-term survival benefits are uncertain due to post-operative complications. Notably, treatment-limiting side effects often arise from an uncontrolled activation of the immune system, particularly peritoneally localized macrophages, leading to massive cytokine secretion and phenotype changes. Exploring alternatives, an increasing number of studies investigated the potential of plasma-activated liquids (PAL) for adjuvant peritoneal cancer treatment, aiming to mitigate side effects, preserve healthy tissue, and reduce cytotoxicity towards non-cancer cells. To assess the non-toxicity of PAL, we isolated primary human macrophages from the peritoneum and subjected them to PAL exposure. Employing an extensive methodological spectrum, including flow cytometry, Raman microspectroscopy, and DigiWest protein analysis, we observed a pronounced resistance of macrophages towards PAL. This resistance was characterized by an upregulation of proliferation and anti-oxidative pathways, countering PAL-derived oxidative stress-induced cell death. The observed cellular effects of PAL treatment on human tissue-resident peritoneal macrophages unveil a potential avenue for PAL-derived immunomodulatory effects within the human peritoneal cavity. Our findings contribute to understanding the intricate interplay between PAL and macrophages, shedding light on the promising prospects for PAL in the adjuvant treatment of peritoneal cancer.
    MeSH term(s) Humans ; Peritoneum/metabolism ; Macrophages, Peritoneal ; Macrophages ; Peritoneal Cavity ; Peritoneal Neoplasms/metabolism ; Oxidative Stress
    Language English
    Publishing date 2024-03-05
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2024.1357340
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Range extension of Micrurus camilae (Serpentes

    Sergio Alejandro Pelaez Plazas / Lilia Alejandra Perlaza Berrio

    Biota Colombiana, Vol 21, Iss

    Elapidae) in the Colombian Caribbean

    2020  Volume 1

    Abstract: We present the first record of the snake Micrurus camilae for the department of Sucre, Colombia, extending its known distribution area and contributing with data about its habitat. The specimen was found in a tropical dry forest patch, in contrast with ... ...

    Abstract We present the first record of the snake Micrurus camilae for the department of Sucre, Colombia, extending its known distribution area and contributing with data about its habitat. The specimen was found in a tropical dry forest patch, in contrast with previous records, in which M. camilae was located in tropical rainforests.
    Keywords bosque seco tropical ; bosque húmedo tropical ; elapidae ; proteroglifa ; rango de distribución ; Biology (General) ; QH301-705.5
    Language English
    Publishing date 2020-01-01T00:00:00Z
    Publisher Instituto de Investigación de Recursos Biológicos Alexander von Humboldt
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Positive selection within the genomes of SARS-CoV-2 and other Coronaviruses independent of impact on protein function

    Alejandro Berrio / Valerie Gartner / Gregory A. Wray

    PeerJ, Vol 8, p e

    2020  Volume 10234

    Abstract: Background The emergence of a novel coronavirus (SARS-CoV-2) associated with severe acute respiratory disease (COVID-19) has prompted efforts to understand the genetic basis for its unique characteristics and its jump from non-primate hosts to humans. ... ...

    Abstract Background The emergence of a novel coronavirus (SARS-CoV-2) associated with severe acute respiratory disease (COVID-19) has prompted efforts to understand the genetic basis for its unique characteristics and its jump from non-primate hosts to humans. Tests for positive selection can identify apparently nonrandom patterns of mutation accumulation within genomes, highlighting regions where molecular function may have changed during the origin of a species. Several recent studies of the SARS-CoV-2 genome have identified signals of conservation and positive selection within the gene encoding Spike protein based on the ratio of synonymous to nonsynonymous substitution. Such tests cannot, however, detect changes in the function of RNA molecules. Methods Here we apply a test for branch-specific oversubstitution of mutations within narrow windows of the genome without reference to the genetic code. Results We recapitulate the finding that the gene encoding Spike protein has been a target of both purifying and positive selection. In addition, we find other likely targets of positive selection within the genome of SARS-CoV-2, specifically within the genes encoding Nsp4 and Nsp16. Homology-directed modeling indicates no change in either Nsp4 or Nsp16 protein structure relative to the most recent common ancestor. These SARS-CoV-2-specific mutations may affect molecular processes mediated by the positive or negative RNA molecules, including transcription, translation, RNA stability, and evasion of the host innate immune system. Our results highlight the importance of considering mutations in viral genomes not only from the perspective of their impact on protein structure, but also how they may impact other molecular processes critical to the viral life cycle.
    Keywords SARS-CoV-2 ; Evolution ; Positive selection ; COVID-19 ; Genome ; Medicine ; R
    Subject code 612
    Language English
    Publishing date 2020-10-01T00:00:00Z
    Publisher PeerJ Inc.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article: Range extension of Micrurus camilae (Serpentes: Elapidae) in the Colombian Caribbean

    Plazas, Sergio Alejandro Pelaez / Berrio, Lilia Alejandra Perlaza

    Biota Colombiana. 2020 Jan., v. 21, no. 1

    2020  

    Abstract: We present the first record of the snake Micrurus camilae for the department of Sucre, Colombia, extending its known distribution area and contributing with data about its habitat. The specimen was found in a tropical dry forest patch, in contrast with ... ...

    Abstract We present the first record of the snake Micrurus camilae for the department of Sucre, Colombia, extending its known distribution area and contributing with data about its habitat. The specimen was found in a tropical dry forest patch, in contrast with previous records, in which M. camilae was located in tropical rainforests.
    Keywords Micrurus ; habitats ; snakes ; tropical dry forests ; Caribbean ; Colombia
    Language English
    Dates of publication 2020-01
    Publishing place Instituto de Investigación de Recursos Biológicos Alexander von Humboldt
    Document type Article
    ZDB-ID 2401299-3
    ISSN 2539-200X
    ISSN 2539-200X
    DOI 10.21068/c2020.v21n01a07
    Database NAL-Catalogue (AGRICOLA)

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  9. Article ; Online: Positive selection within the genomes of SARS-CoV-2 and other Coronaviruses independent of impact on protein function

    Berrio, Alejandro / Gartner, Valerie / Wray, Gregory A.

    bioRxiv

    Abstract: Background: The emergence of a novel coronavirus (SARS-CoV-2) associated with severe acute respiratory disease (COVID-19) has prompted efforts to understand the genetic basis for its unique characteristics and its jump from non-primate hosts to humans. ... ...

    Abstract Background: The emergence of a novel coronavirus (SARS-CoV-2) associated with severe acute respiratory disease (COVID-19) has prompted efforts to understand the genetic basis for its unique characteristics and its jump from non-primate hosts to humans. Tests for positive selection can identify apparently nonrandom patterns of mutation accumulation within genomes, highlighting regions where molecular function may have changed during the origin of a species. Several recent studies of the SARS-CoV-2 genome have identified signals of conservation and positive selection within the gene encoding Spike protein based on the ratio of synonymous to nonsynonymous substitution. Such tests cannot, however, detect changes in the function of RNA molecules. Methods: Here we apply a test for branch-specific oversubstitution of mutations within narrow windows of the genome without reference to the genetic code. Results: We recapitulate the finding that the gene encoding Spike protein has been a target of both purifying and positive selection. In addition, we find other likely targets of positive selection within the genome of SARS-CoV-2, specifically within the genes encoding Nsp4 and Nsp16. Homology-directed modeling indicates no change in either Nsp4 or Nsp16 protein structure relative to the most recent common ancestor. Thermodynamic modeling of RNA stability and structure, however, indicates that RNA secondary structure within both genes in the SARS-CoV-2 genome differs from those of RaTG13, the reconstructed common ancestor, and Pan-CoV-GD (Guangdong). These SARS-CoV-2-specific mutations may affect molecular processes mediated by the positive or negative RNA molecules, including transcription, translation, RNA stability, and evasion of the host innate immune system. Our results highlight the importance of considering mutations in viral genomes not only from the perspective of their impact on protein structure, but also how they may impact other molecular processes critical to the viral life cycle.
    Keywords covid19
    Language English
    Publishing date 2020-09-16
    Publisher Cold Spring Harbor Laboratory
    Document type Article ; Online
    DOI 10.1101/2020.09.16.300038
    Database COVID19

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  10. Article ; Online: Positive selection within the genomes of SARS-CoV-2 and other Coronaviruses independent of impact on protein function

    Berrio, Alejandro / Gartner, Valerie / Wray, Gregory A

    bioRxiv

    Abstract: Background The emergence of a novel coronavirus (SARS-CoV-2) associated with severe acute respiratory disease (COVID-19) has prompted efforts to understand the genetic basis for its unique characteristics and its jump from non-primate hosts to humans. ... ...

    Abstract Background The emergence of a novel coronavirus (SARS-CoV-2) associated with severe acute respiratory disease (COVID-19) has prompted efforts to understand the genetic basis for its unique characteristics and its jump from non-primate hosts to humans. Tests for positive selection can identify apparently nonrandom patterns of mutation accumulation within genomes, highlighting regions where molecular function may have changed during the origin of a species. Several recent studies of the SARS-CoV-2 genome have identified signals of conservation and positive selection within the gene encoding Spike protein based on the ratio of synonymous to nonsynonymous substitution. Such tests cannot, however, detect changes in the function of RNA molecules. Methods Here we apply a test for branch-specific oversubstitution of mutations within narrow windows of the genome without reference to the genetic code. Results We recapitulate the finding that the gene encoding Spike protein has been a target of both purifying and positive selection. In addition, we find other likely targets of positive selection within the genome of SARS-CoV-2, specifically within the genes encoding Nsp4 and Nsp16. Homology-directed modeling indicates no change in either Nsp4 or Nsp16 protein structure relative to the most recent common ancestor. Thermodynamic modeling of RNA stability and structure, however, indicates that RNA secondary structure within both genes in the SARS-CoV-2 genome differs from those of RaTG13, the reconstructed common ancestor, and Pan-CoV-GD (Guangdong). These SARS-CoV-2-specific mutations may affect molecular processes mediated by the positive or negative RNA molecules, including transcription, translation, RNA stability, and evasion of the host innate immune system. Our results highlight the importance of considering mutations in viral genomes not only from the perspective of their impact on protein structure, but also how they may impact other molecular processes critical to the viral life cycle.
    Keywords covid19
    Publisher BioRxiv; WHO
    Document type Article ; Online
    DOI 10.1101/2020.09.16.300038
    Database COVID19

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