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  1. Article ; Online: Bats-The Magnificent Virus Player: SARS, MERS, COVID-19 and Beyond.

    Li, Kenneth S M / Lau, Susanna K P / Woo, Patrick C Y

    Viruses

    2023  Volume 15, Issue 12

    Abstract: Irrespective of whether COVID-19 originated from a natural or a genetically engineered virus, the ultimate source of Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2) is bats [ ... ]. ...

    Abstract Irrespective of whether COVID-19 originated from a natural or a genetically engineered virus, the ultimate source of Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2) is bats [...].
    MeSH term(s) Animals ; Humans ; COVID-19 ; Chiroptera ; SARS-CoV-2/genetics ; Middle East Respiratory Syndrome Coronavirus/genetics
    Language English
    Publishing date 2023-11-29
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2516098-9
    ISSN 1999-4915 ; 1999-4915
    ISSN (online) 1999-4915
    ISSN 1999-4915
    DOI 10.3390/v15122342
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Rapid diagnosis of fatal

    Xing, Fanfan / Xia, Yao / Lu, Qianyun / Lo, Simon K F / Lau, Susanna K P / Woo, Patrick C Y

    Frontiers in medicine

    2023  Volume 10, Page(s) 1226126

    Abstract: ... ...

    Abstract Nocardia
    Language English
    Publishing date 2023-07-18
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2775999-4
    ISSN 2296-858X
    ISSN 2296-858X
    DOI 10.3389/fmed.2023.1226126
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Molecular Research on Emerging Viruses: Evolution, Diagnostics, Pathogenesis, and Therapeutics.

    Lau, Susanna K P

    International journal of molecular sciences

    2018  Volume 19, Issue 2

    Abstract: Viruses are increasingly recognized as emerging infectious disease agents in both humans and animals.[ ... ]. ...

    Abstract Viruses are increasingly recognized as emerging infectious disease agents in both humans and animals.[...].
    MeSH term(s) Animals ; Communicable Diseases, Emerging/diagnosis ; Communicable Diseases, Emerging/genetics ; Communicable Diseases, Emerging/pathology ; Communicable Diseases, Emerging/therapy ; Evolution, Molecular ; Humans ; Virus Diseases/diagnosis ; Virus Diseases/genetics ; Virus Diseases/pathology ; Virus Diseases/therapy
    Keywords covid19
    Language English
    Publishing date 2018-01-30
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms19020398
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Editorial: Emerging and re-emerging viral zoonoses.

    Kumar, Naveen / Uversky, Vladimir N / Tomar, Shailly / Li, Kenneth S M / Chappell, Keith / Lau, Susanna K P

    Frontiers in microbiology

    2022  Volume 13, Page(s) 978259

    Language English
    Publishing date 2022-08-18
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2587354-4
    ISSN 1664-302X
    ISSN 1664-302X
    DOI 10.3389/fmicb.2022.978259
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Listeriosis in a Metropolitan Hospital: Is Targeted Therapy a Risk Factor for Infection?

    Xing, Fanfan / Lo, Simon K F / Lau, Susanna K P / Woo, Patrick C Y

    Frontiers in medicine

    2022  Volume 9, Page(s) 888038

    Abstract: Targeted therapies are widely used for treatment of autoimmune diseases as well as solid organ and hematological malignancies. Various opportunistic infections have been described in patients on targeted therapies. Although case reports or a few case ... ...

    Abstract Targeted therapies are widely used for treatment of autoimmune diseases as well as solid organ and hematological malignancies. Various opportunistic infections have been described in patients on targeted therapies. Although case reports or a few case series of listeriosis have been reported to be associated with targeted therapy, most of the cases were related to anti-tumor necrosis factor-α monoclonal antibody. In this study, we describe the epidemiological and clinical profiles of listeriosis in a tertiary hospital in Shenzhen, a Southern Chinese metropolitan city in China. During the 9-year-and-6-month study period, a total of five cases of listeriosis were recorded and all of them had
    Language English
    Publishing date 2022-04-29
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2775999-4
    ISSN 2296-858X
    ISSN 2296-858X
    DOI 10.3389/fmed.2022.888038
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  6. Article ; Online: Interspecies Jumping of Bat Coronaviruses.

    Wong, Antonio C P / Lau, Susanna K P / Woo, Patrick C Y

    Viruses

    2021  Volume 13, Issue 11

    Abstract: In the last two decades, several coronavirus (CoV) interspecies jumping events have occurred between bats and other animals/humans, leading to major epidemics/pandemics and high fatalities. The SARS epidemic in 2002/2003 had a ~10% fatality. The ... ...

    Abstract In the last two decades, several coronavirus (CoV) interspecies jumping events have occurred between bats and other animals/humans, leading to major epidemics/pandemics and high fatalities. The SARS epidemic in 2002/2003 had a ~10% fatality. The discovery of SARS-related CoVs in horseshoe bats and civets and genomic studies have confirmed bat-to-civet-to-human transmission. The MERS epidemic that emerged in 2012 had a ~35% mortality, with dromedaries as the reservoir. Although CoVs with the same genome organization (e.g.,
    MeSH term(s) Alphacoronavirus/genetics ; Alphacoronavirus/physiology ; Animals ; COVID-19/transmission ; COVID-19/virology ; Chiroptera/virology ; Coronavirus/genetics ; Coronavirus/physiology ; Coronavirus Infections/epidemiology ; Coronavirus Infections/transmission ; Coronavirus Infections/veterinary ; Coronavirus Infections/virology ; Host Adaptation ; Host Specificity ; Humans ; Middle East Respiratory Syndrome Coronavirus/genetics ; Middle East Respiratory Syndrome Coronavirus/physiology ; SARS Virus/genetics ; SARS Virus/physiology ; SARS-CoV-2/genetics ; SARS-CoV-2/physiology ; Severe Acute Respiratory Syndrome/epidemiology ; Severe Acute Respiratory Syndrome/transmission ; Severe Acute Respiratory Syndrome/veterinary ; Severe Acute Respiratory Syndrome/virology
    Language English
    Publishing date 2021-10-29
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 2516098-9
    ISSN 1999-4915 ; 1999-4915
    ISSN (online) 1999-4915
    ISSN 1999-4915
    DOI 10.3390/v13112188
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Molecular Research on Emerging Viruses

    Susanna K. P. Lau

    International Journal of Molecular Sciences, Vol 19, Iss 2, p

    Evolution, Diagnostics, Pathogenesis, and Therapeutics

    2018  Volume 398

    Abstract: Viruses are increasingly recognized as emerging infectious disease agents in both humans and animals.[.] ...

    Abstract Viruses are increasingly recognized as emerging infectious disease agents in both humans and animals.[.]
    Keywords n/a ; Biology (General) ; QH301-705.5 ; Chemistry ; QD1-999
    Language English
    Publishing date 2018-01-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Differential innate immune responses of human macrophages and bronchial epithelial cells against

    Tan, Yen-Pei / Tsang, Chi-Ching / Chan, Ka-Fai / Fung, Siu-Leung / Kok, Kin-Hang / Lau, Susanna K P / Woo, Patrick C Y

    mSphere

    2023  Volume 8, Issue 5, Page(s) e0025822

    Abstract: Talaromyces ... ...

    Abstract Talaromyces marneffei
    MeSH term(s) Humans ; Travel ; Travel-Related Illness ; Macrophages/microbiology ; Immunity, Innate ; Cytokines/metabolism ; Epithelial Cells/metabolism
    Chemical Substances Cytokines
    Language English
    Publishing date 2023-09-11
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 2379-5042
    ISSN (online) 2379-5042
    DOI 10.1128/msphere.00258-22
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Inter-library loan at ZB MED

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  9. Article ; Online: Viruses and Bats.

    Woo, Patrick C Y / Lau, Susanna K P

    Viruses

    2019  Volume 11, Issue 10

    MeSH term(s) Animals ; Chiroptera/classification ; Chiroptera/physiology ; Chiroptera/virology ; Disease Reservoirs ; Humans ; Virus Diseases/epidemiology ; Virus Diseases/transmission ; Virus Diseases/virology ; Virus Physiological Phenomena ; Viruses/classification
    Keywords covid19
    Language English
    Publishing date 2019-09-21
    Publishing country Switzerland
    Document type Editorial ; Research Support, Non-U.S. Gov't
    ZDB-ID 2516098-9
    ISSN 1999-4915 ; 1999-4915
    ISSN (online) 1999-4915
    ISSN 1999-4915
    DOI 10.3390/v11100884
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Rapid Diagnosis of Pneumocystis jirovecii Pneumonia and Respiratory Tract Colonization by Next-Generation Sequencing.

    Xing, Fanfan / Deng, Chaowen / Luo, Zhendong / Zou, Shan / Liu, Min / Ye, Haiyan / Sun, Linlin / Tsang, Chi-Ching / Lo, Simon K F / Lau, Susanna K P / Woo, Patrick C Y

    Mycopathologia

    2024  Volume 189, Issue 3, Page(s) 38

    Abstract: ... diagnosed by next-generation sequencing (NGS) and explore the usefulness of the number of P. jirovecii ... sequence reads for the diagnosis of P. jirovecii pneumonia.: Methods: We examined the NGS results for P ... January to December 2022), P. jirovecii sequences were detected in 56 samples from 53 patients. Fifty (94 ...

    Abstract Objectives: To describe the epidemiology of Pneumocystis jirovecii pneumonia and colonization diagnosed by next-generation sequencing (NGS) and explore the usefulness of the number of P. jirovecii sequence reads for the diagnosis of P. jirovecii pneumonia.
    Methods: We examined the NGS results for P. jirovecii in respiratory samples collected from patients and analysed their clinical, radiological and microbiological characteristics.
    Results: Among 285 respiratory samples collected over a 12-month period (January to December 2022), P. jirovecii sequences were detected in 56 samples from 53 patients. Fifty (94.3%) of the 53 patients were HIV-negative. Following our case definitions, 37 (69.8%) and 16 (30.2%) of the 53 patients had P. jirovecii infection and colonization respectively. P. jirovecii infection was associated with presence of underlying disease with immunosuppression (94.6% vs 18.8%, P < 0.05), positive serum 1,3-β-D-glucan (41.2% vs 0%, P < 0.01) and higher number of P. jirovecii sequence reads (P < 0.005). In contrast, P. jirovecii colonization was associated with the male sex (93.8% vs 54.1%, P < 0.01), another definitive infectious disease diagnosis of the respiratory tract (43.8% vs 2.7%, P < 0.001) and higher survival (100% vs 67.6%, P < 0.01). Although P. jirovecii pneumonia was associated with higher number of P. jirovecii reads in respiratory samples, only a sensitivity of 82.14% and a specificity of 68.75% could be achieved.
    Conclusion: Detection of P. jirovecii sequences in respiratory samples has to be interpreted discreetly. A combination of clinical, radiological and laboratory findings is still the most crucial in determining whether a particular case is genuine P. jirovecii pneumonia.
    MeSH term(s) Humans ; Pneumonia, Pneumocystis/diagnosis ; Pneumonia, Pneumocystis/microbiology ; Male ; High-Throughput Nucleotide Sequencing ; Pneumocystis carinii/genetics ; Pneumocystis carinii/isolation & purification ; Female ; Middle Aged ; Aged ; Adult ; Aged, 80 and over ; Respiratory System/microbiology ; Young Adult ; Molecular Diagnostic Techniques/methods
    Language English
    Publishing date 2024-05-05
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 391081-7
    ISSN 1573-0832 ; 0369-299X ; 0301-486X ; 0027-5530
    ISSN (online) 1573-0832
    ISSN 0369-299X ; 0301-486X ; 0027-5530
    DOI 10.1007/s11046-024-00849-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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