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  1. Article: Possible role of zinc (Zn) as an adjunctive therapy in gastrointestinal symptoms of COVID-19 infectious disease.

    Abbasinazari, Mohammad

    Gastroenterology and hepatology from bed to bench

    2020  Volume 13, Issue 4, Page(s) 417–418

    Language English
    Publishing date 2020-11-27
    Publishing country Iran
    Document type Journal Article
    ZDB-ID 2569124-7
    ISSN 2008-4234 ; 2008-2258
    ISSN (online) 2008-4234
    ISSN 2008-2258
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: A Phase I Randomized, Double-blind, Placebo-controlled Study on Efficacy and Safety Profile of a Sublingually Administered Cannabidiol /Delta 9-tetrahydrocannabidiol (10: 1) Regimen in Diabetes Type 2 Patients.

    Afshar, Shima / Khalili, Shayesteh / Amin, Gholamreza / Abbasinazari, Mohammad

    Iranian journal of pharmaceutical research : IJPR

    2023  Volume 21, Issue 1, Page(s) e132647

    Abstract: The current study aimed to evaluate the safety profile and efficacy of a cannabis-based sublingual spray, ... ...

    Abstract The current study aimed to evaluate the safety profile and efficacy of a cannabis-based sublingual spray, CBDEX10
    Language English
    Publishing date 2023-02-25
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2578271-X
    ISSN 1726-6890 ; 1726-6890 ; 1735-0328
    ISSN (online) 1726-6890
    ISSN 1726-6890 ; 1735-0328
    DOI 10.5812/ijpr-132647
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Drug-induced esophagitis and helpful management for healthcare providers.

    Abdi, Saeed / Masbough, Farnoosh / Nazari, Maryam / Abbasinazari, Mohammad

    Gastroenterology and hepatology from bed to bench

    2022  Volume 15, Issue 3, Page(s) 219–224

    Abstract: In recent decades, the number of cases developing drug-induced esophagitis (DIE) has reportedly been growing, which indicates the significance of detecting medicines capable of causing this adverse reaction. This study aims to provide an updated review ... ...

    Abstract In recent decades, the number of cases developing drug-induced esophagitis (DIE) has reportedly been growing, which indicates the significance of detecting medicines capable of causing this adverse reaction. This study aims to provide an updated review on recent case reports of DIE, to evaluate the possible mechanism of this side effect, and to provide helpful management. Data was gathered through searches of three databases, namely PubMed, Medline, and Cochrane. Seven drug categories were evaluated: antibiotics, bisphosphonates, cardiovascular medicines, chemotherapeutic agents, non-steroidal anti-inflammatory drugs (NSAIDs), other medications, and supplements. According to the findings, retrosternal pain, heartburn, odynophagia, and dysphagia are typical symptoms of DIE, and in most cases, DIE is a self-limiting side effect which can be resolved by removing the causative agent and providing supportive therapy.
    Language English
    Publishing date 2022-10-12
    Publishing country Iran
    Document type Journal Article ; Review
    ZDB-ID 2569124-7
    ISSN 2008-4234 ; 2008-2258
    ISSN (online) 2008-4234
    ISSN 2008-2258
    DOI 10.22037/ghfbb.v15i3.2591
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Case report: Bilateral simple Syndactyly in a toddler with maternal exposure to cabergoline.

    Afshar, Shima / Abbasinazari, Mohammad / Darvishi, Behnam / Ziaie, Shadi / Esmaily, Hadi

    Clinical case reports

    2022  Volume 10, Issue 5, Page(s) e05795

    Abstract: Cabergoline is routinely prescribed in the management of prolactin excreting adenomas and is associated with low risk of congenital malformations and teratogenicity. Here, we reported the case of a bilateral simple syndactyly in a toddler with maternal ... ...

    Abstract Cabergoline is routinely prescribed in the management of prolactin excreting adenomas and is associated with low risk of congenital malformations and teratogenicity. Here, we reported the case of a bilateral simple syndactyly in a toddler with maternal exposure to cabergoline during the pregnancy. This association has not been previously described before.
    Language English
    Publishing date 2022-05-04
    Publishing country England
    Document type Case Reports
    ZDB-ID 2740234-4
    ISSN 2050-0904
    ISSN 2050-0904
    DOI 10.1002/ccr3.5795
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Role of vitamin C and rectal indomethacin in preventing and alleviating post-endoscopic retrograde cholangiopancreatography pancreatitis: a clinical study.

    Sadeghi, Amir / Jafari-Moghaddam, Rana / Ataei, Sara / Asadiafrooz, Mahboobe / Abbasinazari, Mohammad

    Clinical endoscopy

    2023  Volume 56, Issue 2, Page(s) 214–220

    Abstract: Background/aims: This study aimed to determine whether vitamin C in addition to indomethacin decreases the occurrence and severity of post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP) occurrence and severity.: Methods: ... ...

    Abstract Background/aims: This study aimed to determine whether vitamin C in addition to indomethacin decreases the occurrence and severity of post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP) occurrence and severity.
    Methods: This randomized clinical trial included patients undergoing ERCP. The participants were administered either rectal indomethacin (100 mg) plus an injection of vitamin C (500 mg) or rectal indomethacin (100 mg) alone just before ERCP. The primary outcomes were PEP occurrence and severity. The secondary amylase and lipase levels were determined after 24 hours.
    Results: A total of 344 patients completed the study. Based on intention-to-treat analysis, the PEP rates were 9.9% for indomethacin plus vitamin C plus indomethacin and 15.7% for indomethacin alone. Regarding the per-protocol analysis, the PEP rates were 9.7% and 15.7% in the combination and indomethacin arms, respectively. There was a remarkable difference between the two arms in PEP occurrence and severity on intention-to-treat and per-protocol analyses (p=0.034 and p=0.031, respectively). The post-ERCP lipase and amylase concentrations were lower in the combination arm than in the indomethacin alone arm (p=0.034 and p=0.029, respectively).
    Conclusion: Vitamin C injection in addition to rectal indomethacin reduced PEP occurrence and severity.
    Language English
    Publishing date 2023-03-06
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 2643507-X
    ISSN 2234-2443 ; 2234-2400
    ISSN (online) 2234-2443
    ISSN 2234-2400
    DOI 10.5946/ce.2022.165
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Effect of folic acid on the sexual function of postmenopausal women: a triple-blind randomized controlled trial.

    Asadi, Mahnaz / Riazi, Hedyeh / Abbasinazari, Mohammad / Majd, Hamid Alavi / Montazeri, Ali

    The journal of sexual medicine

    2023  Volume 20, Issue 9, Page(s) 1180–1187

    Abstract: Background: There are reports of sexual dysfunction in postmenopausal women, and several treatment recommendations are available.: Aim: To investigate the effect of folic acid on postmenopausal women's sexual function.: Methods: This triple-blind ... ...

    Abstract Background: There are reports of sexual dysfunction in postmenopausal women, and several treatment recommendations are available.
    Aim: To investigate the effect of folic acid on postmenopausal women's sexual function.
    Methods: This triple-blind randomized controlled trial was conducted in Tehran, Iran, in 2020. A sample of 100 postmenopausal women was recruited from comprehensive health centers affiliated with the Shahid Beheshti University of Medical Sciences. Eligible women were randomly assigned to receive folic acid (5 mg) or placebo on an empty stomach every day for 8 weeks. Women were assessed at 3 time points: baseline and 4 and 8 weeks after the intervention.
    Outcome: Sexual function was the main outcome, as measured by the Female Sexual Function Index.
    Results: The mean ± SD age of participants in the folic acid and placebo groups was 53.2 ± 3.84 and 54.4 ± 4.05 years, respectively (P = .609). The results obtained from mixed effects analysis of variance revealed a statistically significant difference between baseline and posttreatment scores and the interaction between time and group for desire, orgasm, satisfaction, arousal, pain, and total sexual function score, with the folic acid group improving more than control group. Lubrication was the only domain that showed no significant difference for the interaction between time and group.
    Clinical implications: Folic acid may beneficially affect sexual function in postmenopausal women.
    Strengths and limitations: Strengths include the novelty of the subject, the triple-blind design, the block randomization, the administration of a standard scale for sexual function (Female Sexual Function Index), and the affordability and availability of folic acid. This study was conducted with a small sample size and short follow-up time; therefore, interpretation of the results requires great caution.
    Conclusion: The findings suggest that folic acid possibly improves sexual function in postmenopausal women. Larger studies are needed to confirm the findings.
    Trial registration: IRCT20150128020854N8; August 2, 2020. Iranian Registry of Clinical Trials; https://en.irct.ir/user/trial/48920/view.
    MeSH term(s) Female ; Humans ; Middle Aged ; Postmenopause ; Iran ; Sexual Dysfunction, Physiological/drug therapy ; Orgasm
    Language English
    Publishing date 2023-07-06
    Publishing country Netherlands
    Document type Randomized Controlled Trial ; Journal Article
    ZDB-ID 2251959-2
    ISSN 1743-6109 ; 1743-6095
    ISSN (online) 1743-6109
    ISSN 1743-6095
    DOI 10.1093/jsxmed/qdad086
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Is the Addition of Sublingual Melatonin to Omeprazole Superior to Omeprazole Alone in the Management of Gastroesophageal Reflux Disease Symptoms: A Clinical Trial.

    Malekpour, Habib / Noori, Amin / Abdi, Saeed / Abbasinazari, Mohammad / Mahboubi, Arash / Ghamsari, Mahdiye Abiyar

    The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology

    2023  Volume 34, Issue 12, Page(s) 1206–1211

    Abstract: Background/aims: Proton pump inhibitors are frequently used to treat gastroesophageal reflux disease, but their effect is restricted. The present study aimed to investigate whether the addition of sublingual melatonin to omeprazole was effective in the ... ...

    Abstract Background/aims: Proton pump inhibitors are frequently used to treat gastroesophageal reflux disease, but their effect is restricted. The present study aimed to investigate whether the addition of sublingual melatonin to omeprazole was effective in the treatment of gastro gastroesophageal reflux disease symptoms.
    Materials and methods: This was a randomized double-blind clinical trial. A total of 78 patients with gastro gastroesophageal reflux disease were randomly allocated to either omeprazole 20 mg/d plus sublingual melatonin (3 mg/d) or omeprazole 20 mg/d plus placebo for 4 weeks. The selected patients had histories of heartburn and regurgitation and a score ≤32 on the Frequency Scale for the Symptoms of gastroesophageal reflux disease (FSSG). The outcome measures for the assessment of treatment efficacy were heartburn, epigastric pain and the Frequency Scale for the Symptoms of gastroesophageal reflux disease score. Safety and quality of life were evaluated in the patients as the secondary outcomes too.
    Results: Seventy-two out of 78 eligible patients completed this trial (35 in the melatonin group and 37 in the placebo group). Heartburn, epigastric pain, and Frequency Scale for the Symptoms of gastroesophageal reflux disease score declined significantly in the melatonin group compared to the placebo group (P = .04, P = .03, and P = .0001, respectively). Moreover, the quality of life score was significantly higher in the melatonin group compared with the placebo group (P = .0001). Adverse events were similarly observed in the 2 groups (P = .55), and there were no serious adverse events.
    Conclusion: The combination of sublingual melatonin (3 mg/day) with omeprazole (20 mg/day) may be more effective than omeprazole (20 mg/day) alone in the treatment of gastroesophageal reflux disease.
    MeSH term(s) Humans ; Omeprazole/adverse effects ; Heartburn/drug therapy ; Heartburn/etiology ; Melatonin/therapeutic use ; Quality of Life ; Gastroesophageal Reflux/complications ; Proton Pump Inhibitors/therapeutic use ; Treatment Outcome ; Pain/chemically induced ; Pain/complications ; Pain/drug therapy ; Double-Blind Method
    Chemical Substances Omeprazole (KG60484QX9) ; Melatonin (JL5DK93RCL) ; Proton Pump Inhibitors
    Language English
    Publishing date 2023-09-28
    Publishing country Turkey
    Document type Randomized Controlled Trial ; Journal Article
    ZDB-ID 1340275-4
    ISSN 2148-5607 ; 1300-4948
    ISSN (online) 2148-5607
    ISSN 1300-4948
    DOI 10.5152/tjg.2023.23021
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Endocannabinoids and related compounds as modulators of angiogenesis: Concepts and clinical significance.

    Afshar, Shima / Abbasinazari, Mohammad / Amin, Gholamreza / Farrokhian, Amir / Sistanizad, Mohammad / Afshar, Fariba / Khalili, Shayesteh

    Cell biochemistry and function

    2022  Volume 40, Issue 8, Page(s) 826–837

    Abstract: Vasculogenesis (the process of differentiation of angioblasts toward endothelial cells and de novo formation of crude vascular networks) and angiogenesis (the process of harmonized sprouting and dispersal of new capillaries from previously existing ones) ...

    Abstract Vasculogenesis (the process of differentiation of angioblasts toward endothelial cells and de novo formation of crude vascular networks) and angiogenesis (the process of harmonized sprouting and dispersal of new capillaries from previously existing ones) are two fundamentally complementary processes, obligatory for maintaining physiological functioning of vascular system. In clinical practice, however, the later one is of more importance as it guarantees correct embryonic nourishment, accelerates wound healing processes, prevents uncontrolled cell growth and tumorigenesis, contributes in supplying nutritional demand following occlusion of coronary vessels and is in direct relation with development of diabetic retinopathy. Hence, discovery of novel molecules capable of modulating angiogenic events are of great clinical importance. Recent studies have demonstrated multiple angio-regulatory activities for endocannabinoid system modulators and endocannabinoid-like molecules, as well as their metabolizing enzymes. Hence, in present article, we reviewed the regulatory roles of these molecules on angiogenesis and described molecular mechanisms underlying them.
    Language English
    Publishing date 2022-11-01
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 283643-9
    ISSN 1099-0844 ; 0263-6484
    ISSN (online) 1099-0844
    ISSN 0263-6484
    DOI 10.1002/cbf.3754
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: A Comprehensive Review of the Role of Complementary and Dietary Medicines in Eradicating

    Abdi, Saeed / Ataei, Sara / Abroon, Maede / Majma Sanaye, Pantea / Abbasinazari, Mohammad / Farrokhian, Amir

    Iranian journal of pharmaceutical research : IJPR

    2022  Volume 21, Issue 1, Page(s) e127030

    Abstract: Antibiotic- ... ...

    Abstract Antibiotic-resistant
    Language English
    Publishing date 2022-06-18
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 2578271-X
    ISSN 1726-6890 ; 1726-6890 ; 1735-0328
    ISSN (online) 1726-6890
    ISSN 1726-6890 ; 1735-0328
    DOI 10.5812/ijpr-127030
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Probable QT Prolongation between Chloroquine/Hydroxychloroquine in Treatment of COVID-19 Infection and other Medications

    Abbasinazari, Mohammad / Azizian, Homa

    Journal of Cellular & Molecular Anesthesia; Vol. 5 No.; 2476-5120 ; 2538-2462

    2020  Volume 3, Issue : July 2020

    Keywords Chloroquine ; Hydroxychloroquine ; Covid-19 ; QT prolongation ; drug interaction ; covid19
    Language English
    Publishing date 2020-05-07
    Publisher Anesthesiology Research Center, Shahid Beheshti University of Medical Sciences
    Publishing country ir
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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