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  1. Article: Post-Endoscopy Sialadenitis.

    Molakatalla, Phani / Govil, Yogesh

    ACG case reports journal

    2015  Volume 2, Issue 2, Page(s) 65–66

    Language English
    Publishing date 2015-01-16
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2814825-3
    ISSN 2326-3253
    ISSN 2326-3253
    DOI 10.14309/crj.2015.2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: How does length of stay in the United States affect colorectal cancer incidence among immigrant Asian populations in California?

    Molakatalla, Phani K / Kumar, Anand R

    The American journal of gastroenterology

    2014  Volume 109, Issue 10, Page(s) 1687

    MeSH term(s) Asian Americans ; Colorectal Neoplasms/ethnology ; Emigrants and Immigrants ; Female ; Humans ; Male ; Residence Characteristics ; Social Class
    Language English
    Publishing date 2014-10
    Publishing country United States
    Document type Comment ; Letter
    ZDB-ID 390122-1
    ISSN 1572-0241 ; 0002-9270
    ISSN (online) 1572-0241
    ISSN 0002-9270
    DOI 10.1038/ajg.2014.248
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Outcomes with conversion from calcineurin inhibitors to sirolimus after renal transplantation in the context of steroid withdrawal or steroid continuation.

    Egbuna, Ogo I / Davis, Roger B / Chudinski, Robyn / Pavlakis, Martha / Rogers, Christin / Molakatalla, Phani / Johnson, Scott R / Karp, Seth / Monaco, Anthony P / Tang, Hongying / Hanto, Douglas W / Mandelbrot, Didier A

    Transplantation

    2009  Volume 88, Issue 5, Page(s) 684–692

    Abstract: Background: A number of studies have suggested that conversion from calcineurin inhibitors (CNI) to sirolimus (SRL) can improve graft function in renal transplant patients. None of these studies has converted patients to SRL in the absence of steroids.!# ...

    Abstract Background: A number of studies have suggested that conversion from calcineurin inhibitors (CNI) to sirolimus (SRL) can improve graft function in renal transplant patients. None of these studies has converted patients to SRL in the absence of steroids.
    Methods: We describe our experience with 278 renal transplants of which 153 were converted from CNI to SRL. The majority of patients had steroids withdrawn after 6 days. Almost all patients received antithymocyte globulin induction and were maintained on mycophenolate mofetil.
    Results: Six months after conversion, patients remaining on SRL therapy had a mean increase in estimated glomerular filtration rate of 6.93 mL/min/1.73 m2 (P<0.0001) compared with preconversion values. SRL-converted patients analyzed by intention-to-treat increased estimated glomerular filtration rate by 5.00 mL/min/1.73 m2 (P=0.0005). Eighty-one percent of patients remaining on SRL had a successful conversion, defined as stable or improved renal function at 6 months. The only factor predictive of unsuccessful conversion was urine protein-to-creatinine ratio more than 1. The benefits of SRL conversion were seen in patients at high immunological risk as well as those at lower risk. Proteinuria increased by a mean of 0.1 (P=0.43) at 6 months. Thirty-six percent of SRL-converted patients experienced adverse effects requiring conversion back to CNI. Rates of rejection, graft loss, and patient death with SRL conversion were low.
    Conclusions: The results from our clinical practice suggest that even in the absence of steroids, SRL conversion significantly improves renal function, with acceptable rates of adverse events.
    MeSH term(s) Adolescent ; Adult ; Aged ; Antilymphocyte Serum/therapeutic use ; Calcineurin Inhibitors ; Child ; Child, Preschool ; Female ; Humans ; Immunosuppressive Agents/therapeutic use ; Infant ; Infant, Newborn ; Kidney Transplantation/methods ; Male ; Middle Aged ; Mycophenolic Acid/analogs & derivatives ; Mycophenolic Acid/therapeutic use ; Sirolimus/pharmacology ; Steroids/therapeutic use ; Treatment Outcome
    Chemical Substances Antilymphocyte Serum ; Calcineurin Inhibitors ; Immunosuppressive Agents ; Steroids ; Mycophenolic Acid (HU9DX48N0T) ; Sirolimus (W36ZG6FT64)
    Language English
    Publishing date 2009-09-15
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 208424-7
    ISSN 1534-6080 ; 0041-1337
    ISSN (online) 1534-6080
    ISSN 0041-1337
    DOI 10.1097/TP.0b013e3181b27d44
    Database MEDical Literature Analysis and Retrieval System OnLINE

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