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  1. Article ; Online: Comment on: Letermovir for Cytomegalovirus prophylaxis in pediatric hematopoietic cell transplantation.

    Styczynski, Jan

    Pediatric blood & cancer

    2023  Volume 70, Issue 12, Page(s) e30692

    Language English
    Publishing date 2023-09-23
    Publishing country United States
    Document type Letter
    ZDB-ID 2131448-2
    ISSN 1545-5017 ; 1545-5009
    ISSN (online) 1545-5017
    ISSN 1545-5009
    DOI 10.1002/pbc.30692
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Book ; Online: EQUAL Trichosporon Score 2022

    Sprute, Rosanne / Bethe, Ullrich / Chen, Shuang / Cornely, Oliver Andreas / Styczyński, Jan

    Punktacja ECMM w ocenie jakości postępowania klinicznego w inwazyjnym zakażeniu Trichosporon

    (EQUAL Trichosporon Scorecard)

    2023  

    Abstract: EQUAL Trichosporon Score łączy parametry optymalnej terapii inwazyjnych zakażeń Trichosporon. Karta wyników EQUAL odzwierciedla najsilniejsze zalecenia i rekomendacje z aktualnych różnych wytycznych. Karta EQAUL stanowi szybkie odniesienie do analizy ... ...

    Title variant EQUAL Trichosporon Score 2022: ECMM Score in assessment of the quality of clinical management in invasive procedures Trichosporon infection
    Institution Universitätsklinikum Köln / Klinik I für Innere Medizin
    Author's details Rosanne Sprute, Ullrich Bethe1, Sharon C.-A. Chen, Oliver A. Cornely, Jan Styczyński ; Uniklinik Köln, DZIF - Deutsches Zentrum für Infektionsforschung, The University of Sydney, NSW Government - Health Pathology, ECMM - European Confederation of Medical Mycology
    Series title EQUAL Trichosporon Scorecard
    Abstract EQUAL Trichosporon Score łączy parametry optymalnej terapii inwazyjnych zakażeń Trichosporon. Karta wyników EQUAL odzwierciedla najsilniejsze zalecenia i rekomendacje z aktualnych różnych wytycznych. Karta EQAUL stanowi szybkie odniesienie do analizy przestrzegania wytycznych i zarządzania środkami przeciwgrzybiczymi.
    Subject code 610
    Language Polish
    Size 1 Online-Ressource (2 Blätter)
    Publisher Uniklinik Köln
    Publishing place Cologne
    Publishing country Germany
    Document type Book ; Online
    HBZ-ID HT030069916
    DOI 10.4126/FRL01-006453162
    Database Repository for Life Sciences

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  3. Book ; Online: EQUAL CPA Score 2022

    Sprute, Rosanne / Braeckel, Eva van / Flick, Holger / Cornely, Oliver Andreas / Seidel, Danila / Styczyński, Jan

    Punktacja ECMM w ocenie jakości postępowania klinicznego w Przewlekłej Aspergillozie Płucnej

    (EQUAL CPA Scorecard)

    2023  

    Abstract: Punktacja EQUAL CPA Score 2022 zawiera zalecenia z aktualnych wytycznych dotyczących postępowania w przewlekłej aspergilozie płucnej (CPA) [1][2]. Wynik EQUAL można wykorzystać do oceny przestrzegania wytycznych postępowania klinicznego [3]. CPA to ... ...

    Title variant EQUAL CPA Score 2022: ECMM score in the assessment quality of clinical management in Chronic Pulmonary Aspergillosis
    Institution Universitätsklinikum Köln / Klinik I für Innere Medizin
    Author's details Rosanne Sprute, Eva Van Braeckel, Holger Flick, Oliver A.Cornely, Danila Seidel, Jan Styczyński ; Uniklinik Köln, Ghent University, Med Uni Graz, Odense Respiratory Research Unit, DZIF - Deutsches Zentrum für Infektionsforschung, CPAnet - Chronic Pulmonary Aspergillosis Network, ECMM - European Confederation of Medical Mycology
    Series title EQUAL CPA Scorecard
    Abstract Punktacja EQUAL CPA Score 2022 zawiera zalecenia z aktualnych wytycznych dotyczących postępowania w przewlekłej aspergilozie płucnej (CPA) [1][2]. Wynik EQUAL można wykorzystać do oceny przestrzegania wytycznych postępowania klinicznego [3]. CPA to wyniszczająca przewlekła grzybica płuc. Dotyczy osób immunokompetentnych oraz osób z łagodnym upośledzeniem odporności z chorobą płuc. Rozpoznanie jest trudne, ponieważ obraz kliniczny jest niespecyficzny, a wyniki badań radiologicznych są niejednorodne. Niektóre choroby powinny budzić podejrzenie CPA w przypadku występowania niewyjaśnionych objawów płucnych lub ogólnoustrojowych. Należą do nich gruźlica i niegruźlicze choroby mykobakteryjne, przewlekła obturacyjna choroba płuc, rak płuc i sarkoidoza. Zakażenie może prowadzić do powstawania guzków płucnych, ubytków, wtórnego zgrubienia opłucnej i zwłóknienia.
    Subject code 610
    Language Polish
    Size 1 Online-Ressource (2 Blätter), Illustrationen
    Publisher Uniklinik Köln
    Publishing place Cologne
    Publishing country Germany
    Document type Book ; Online
    Note Open Access
    HBZ-ID HT030069838
    DOI 10.4126/FRL01-006453156
    Database Repository for Life Sciences

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  4. Book ; Online: EQUAL Scedosporiosis/Lomentosporiosis Score 2021

    Stemler, Jannik / Lackner, Michaela / Chen, Shuang / Hoenigl, Martin / Cornely, Oliver Andreas / Styczyński, Jan

    Punktacja ECMM w ocenie jakości postępowania klinicznego w Scedosporiozie/Lomentosporiozie

    (EQUAL Scedosporiosis/Lomentosporiosis Scorecard)

    2023  

    Abstract: Punktacja EQUAL Scedosporiosis/Lomentosporiosis Score łączy parametry optymalnej terapii scedosporiosis i lomentosporiosis. Karta wyników EQUAL stanowi szybkie odniesienie do ilościowego określenia przestrzegania wytycznych i wspierania postępowania ... ...

    Title variant EQUAL Scedosporiosis/Lomentosporiosis Score 2021: ECMM scoring in the assessment of the quality of proceedings in Scedosporiosis/Lomentosporiasis
    Institution Universitätsklinikum Köln / Klinik I für Innere Medizin
    Author's details Jannik Stemler, Michaela Lackner, Sharon Chen, Martin Hoenigl, Oliver A. Cornely, Jan Styczyński ; Uniklinik Köln, Medical University of Graz, The University of Sydney, Medizinische Universität Innsbruck, ECMM - European Confederation of Medical Mycology
    Series title EQUAL Scedosporiosis/Lomentosporiosis Scorecard
    Abstract Punktacja EQUAL Scedosporiosis/Lomentosporiosis Score łączy parametry optymalnej terapii scedosporiosis i lomentosporiosis. Karta wyników EQUAL stanowi szybkie odniesienie do ilościowego określenia przestrzegania wytycznych i wspierania postępowania przeciwgrzybiczego.
    Subject code 610
    Language Polish
    Size 1 Online-Ressource (2 Blätter), Illustrationen
    Publisher Uniklinik Köln
    Publishing place Cologne
    Publishing country Germany
    Document type Book ; Online
    Note Open Access
    HBZ-ID HT030069843
    DOI 10.4126/FRL01-006453158
    Database Repository for Life Sciences

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  5. Article ; Online: Hematology and transfusion medicine facing COVID-19

    Styczyński, Jan

    Acta Haematologica Polonica

    perspectives beyond the pandemic

    2020  Volume 51, Issue 2, Page(s) 58–59

    Keywords covid19
    Publisher Walter de Gruyter GmbH
    Publishing country de
    Document type Article ; Online
    ZDB-ID 2704533-X
    ISSN 2300-7117 ; 0001-5814
    ISSN (online) 2300-7117
    ISSN 0001-5814
    DOI 10.2478/ahp-2020-0013
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Who is the patient at risk for EBV reactivation and disease: expert opinion focused on post-transplant lymphoproliferative disorders following hematopoietic stem cell transplantation.

    Marjanska, Agata / Styczynski, Jan

    Expert opinion on biological therapy

    2023  Volume 23, Issue 6, Page(s) 539–552

    Abstract: Introduction: Post-transplant lymphoproliferative disorders (PTLD) represent a diverse group of diseases. They develop as a consequence of uncontrolled proliferation of lymphoid or plasmacytic cells resulting from T-cell immunosuppression after ... ...

    Abstract Introduction: Post-transplant lymphoproliferative disorders (PTLD) represent a diverse group of diseases. They develop as a consequence of uncontrolled proliferation of lymphoid or plasmacytic cells resulting from T-cell immunosuppression after transplantation of either hematopoietic cells (HCT) or solid organs (SOT), caused mainly by latent Epstein-Barr virus (EBV). The risk for EBV recurrence is dependent on the level of incompetency of the immune system, presented as an impairment of T-cell immunity.
    Areas covered: This review summarizes the data on incidence and risk factors of EBV infection in patients after HCT. The median rate of EBV infection in HCT recipients was estimated at 30% after allogeneic and<1% after autologous transplant; 5% in non-transplant hematological malignancies; 30% in SOT recipients. The median rate of PTLD after HCT is estimated at 3%. The most frequently reported risk factors for EBV infection and disease include: donor EBV-seropositivity, use of T-cell depletion, especially with ATG; reduced-intensity conditioning; mismatched family or unrelated donor transplants; and acute or chronic graft-versus-host-disease.
    Expert opinion: The major risk factors for EBV infection and EBV-PTLD can be easily identified: EBV-seropositive donor, depletion of T-cells, and the use of immunosuppressive therapy. Strategies for avoiding risk factors include elimination EBV from the graft and improving T-cell function.
    MeSH term(s) Humans ; Epstein-Barr Virus Infections/epidemiology ; Epstein-Barr Virus Infections/therapy ; Herpesvirus 4, Human ; Expert Testimony ; Hematopoietic Stem Cell Transplantation/adverse effects ; Lymphoproliferative Disorders/epidemiology ; Lymphoproliferative Disorders/etiology ; Lymphoproliferative Disorders/pathology
    Language English
    Publishing date 2023-03-28
    Publishing country England
    Document type Review ; Journal Article
    ZDB-ID 2052501-1
    ISSN 1744-7682 ; 1471-2598
    ISSN (online) 1744-7682
    ISSN 1471-2598
    DOI 10.1080/14712598.2023.2196366
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Book ; Online: EQUAL Skala Aspergillozy 2018

    Cornely, Oliver Andreas / Köhler, Philipp / Mellinghoff, Sibylle Christiane / Styczyński, Jan

    an ECMM Score Derived From Current Guidelines to Measure QUALity of Clinical Invasive Pulmonary Aspergillosis Management

    (EQUAL Aspergillosis Scorecard)

    2019  

    Institution Universitätsklinikum Köln / Klinik I für Innere Medizin
    Author's details Cornely, O.A., Koehler, P., Mellinghoff, S.C., Styczyński, J. ; Uniklinik Köln
    Series title EQUAL Aspergillosis Scorecard
    Subject code 610
    Language Polish
    Size 1 Online-Ressource (2 Blätter)
    Edition Maj 2019
    Publisher Uniklinik Köln
    Publishing place Köln
    Publishing country Germany
    Document type Book ; Online
    Note Open Access
    HBZ-ID HT020105074
    DOI 10.4126/FRL01-006414817
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  8. Book ; Online: EQUAL Candida Score 2018

    Mellinghoff, Sibylle Christiane / Köhler, Philipp / Cornely, Oliver Andreas / Styczyński, Jan

    Wynik ECMM uzyskany na podstawie aktualnych wytycznych do pomiaru jakości (QUALity)zarządzania kandydatami klinicznymi

    2019  

    Institution Universitätsklinikum Köln / Klinik I für Innere Medizin
    Author's details Mellinghoff, S.C., Köhler, P., Cornely, O.A., Styczynski, J. ; Uniklinik Köln
    Subject code 610
    Language Polish
    Size 1 Online-Ressource (2 Blätter)
    Edition Maj 2019
    Publisher Uniklinik Köln
    Publishing place Köln
    Publishing country Germany
    Document type Book ; Online
    Note Open Access
    HBZ-ID HT020105096
    DOI 10.4126/FRL01-006414818
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  9. Article: The Role of Hepcidin in Myelodysplastic Syndromes (MDS): A Systematic Review of Observational Studies.

    Słomka, Artur / Pokrzywa, Anna / Strzała, Dominika / Kubiaczyk, Maja / Wesolowska, Oliwia / Denkiewicz, Kinga / Styczyński, Jan

    Cancers

    2024  Volume 16, Issue 2

    Abstract: Iron overload emerges as a serious complication in myelodysplastic syndromes (MDS), particularly associated with frequent transfusions during the course of the disease. The discovery and description of hepcidin's mechanisms of action have contributed to ... ...

    Abstract Iron overload emerges as a serious complication in myelodysplastic syndromes (MDS), particularly associated with frequent transfusions during the course of the disease. The discovery and description of hepcidin's mechanisms of action have contributed to a deeper understanding of iron metabolism. The existing literature reports a potential role of hepcidin in MDS, yet these data are fragmented and presented in an unstructured, somewhat chaotic manner. Hence, to address the existing data, we performed a systematic review of observational studies examining hepcidin levels in MDS. An extensive review of three bibliographic databases (Pubmed, Web of Science, and Scopus) enabled us to identify 12 observational studies. These studies focused primarily on adult patients with low-risk MDS who underwent transfusions and chelation therapy. An in-depth analysis of these manuscripts led to four main conclusions: (1) although high serum hepcidin levels are associated with MDS, most studies generally have not found a significant difference in these levels between patients and healthy individuals; (2) serum hepcidin levels are specific to MDS type; (3) serum hepcidin levels in MDS are strongly associated with transfusions and the genetic status of patients; and (4) high-risk MDS is associated with high serum hepcidin levels. While we have furnished a comprehensive summary of the significance of hepcidin in MDS, there are still gaps that future research should address. This pertains primarily to the capacity of hepcidin in predicting adverse outcomes for MDS patients and evaluating the efficacy of chelation therapy or the need for transfusion.
    Language English
    Publishing date 2024-01-11
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers16020332
    Database MEDical Literature Analysis and Retrieval System OnLINE

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