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Article ; Online: Twelve tips for optimising learning for postgraduate doctors in the operating theatre.

Chatterton, Benjamin D / Sharma, Nikhil / Rees, Eliot L / Hadfield-Law, Lisa / Jermin, Paul J / Banerjee, Robin / Kiely, Nigel T

Medical teacher

2023 Volume 45, Issue 9, Page(s) 972–977

Abstract: Learning in the operating theatre forms a critical part of postgraduate medical education. Postgraduate doctors present a diverse cohort of learners with a wide range of learning needs that will vary by their level of experience and curriculum ... ...

Abstract	Learning in the operating theatre forms a critical part of postgraduate medical education. Postgraduate doctors present a diverse cohort of learners with a wide range of learning needs that will vary by their level of experience and curriculum requirements. With evidence of both trainee dissatisfaction with the theatre learning experience and reduced time spent in the operating theatre, which has been exacerbated by the effects of the Covid-19 pandemic, it is vital that every visit to the operating theatre is used as a learning opportunity. We have devised 12 tips aimed at both learners and surgeons to optimise learning in the operating theatre, set out into four domains: educational context, preparation, learning in theatre, feedback and reflection. These tips have been created by a process of literature review and acknowledgment of established learning theory, with further discussion amongst surgical trainees, senior surgical faculty, surgical educators and medical education faculty.
MeSH term(s)	Humans ; COVID-19 ; Curriculum ; Learning ; Operating Rooms ; Pandemics
Language	English
Publishing date	2023-04-27
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	424426-6
ISSN	1466-187X ; 0142-159X
ISSN (online)	1466-187X
ISSN	0142-159X
DOI	10.1080/0142159X.2023.2206536
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Article ; Online: Is preoperative advanced vascular imaging necessary in pediatric C1-C2 spinal fusion?

Kiely, Paul D / Asghar, Jahangir K

The spine journal : official journal of the North American Spine Society

2016 Volume 16, Issue 4, Page(s) 564–565

MeSH term(s)	Atlanto-Axial Joint/diagnostic imaging ; Atlanto-Axial Joint/surgery ; Bone Screws/adverse effects ; Cervical Vertebrae/diagnostic imaging ; Cervical Vertebrae/surgery ; Child ; Female ; Humans ; Male ; Postoperative Complications/prevention & control ; Spinal Fusion/adverse effects ; Spinal Fusion/methods
Language	English
Publishing date	2016
Publishing country	United States
Document type	Letter
ZDB-ID	2037072-6
ISSN	1878-1632 ; 1529-9430
ISSN (online)	1878-1632
ISSN	1529-9430
DOI	10.1016/j.spinee.2015.08.056
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Article ; Online: Letter to the editor: Off-label rhBMP-2 use in pediatric spine deformity surgery.

Kiely, Paul D / Cunningham, Matthew E

Journal of neurosurgery. Pediatrics

2015 Volume 15, Issue 5, Page(s) 545–546

MeSH term(s)	Bone Morphogenetic Protein 2/therapeutic use ; Female ; Humans ; Male ; Practice Patterns, Physicians'/statistics & numerical data ; Spinal Fusion/methods ; Spinal Fusion/statistics & numerical data ; Spine/surgery ; Transforming Growth Factor beta/therapeutic use
Chemical Substances	Bone Morphogenetic Protein 2 ; Transforming Growth Factor beta
Language	English
Publishing date	2015-05
Publishing country	United States
Document type	Comment ; Letter
ZDB-ID	2403985-8
ISSN	1933-0715 ; 1933-0707
ISSN (online)	1933-0715
ISSN	1933-0707
DOI	10.3171/2014.11.PEDS14628
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Article: Navigating Work-Life Integration, Legal Issues, Patient Safety: Lessons for Work-Life Wellness in Academic Medicine: Part 1 of 3.

Hartwell, Jennifer L / Barach, Paul / Gunter, Tracy D / Reed, Kyra / Kelker, Heather / Welch, Julie / Olson, Kristine / Harry, Elizabeth / Meltzer-Brody, Samantha / Quinn, Mariah / Ferrand, Jennifer / Kiely, Sharon C / Hartsock, Jane / Holmes, Emily / Schroeder, Kristin / Ahmed, Rami

Kansas journal of medicine

2023 Volume 16, Page(s) 153–158

Language	English
Publishing date	2023-06-20
Publishing country	United States
Document type	Journal Article
ISSN	1948-2035
ISSN	1948-2035
DOI	10.17161/kjm.vol16.19952
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Article ; Online: Information Avoidance and Information Seeking Among Parents of Children With ASD.

Sicherman, Nachum / Law, Kiely / Lipkin, Paul H / Loewenstein, George / Marvin, Alison R / Buxbaum, Joseph D

American journal on intellectual and developmental disabilities

2021 Volume 126, Issue 3, Page(s) 249–259

Abstract: We estimated the effects of information avoidance and information seeking among parents of children diagnosed with autism spectrum disorder (ASD) on age of diagnosis. An online survey was completed by 1,815 parents of children with ASD. Children of ... ...

Abstract	We estimated the effects of information avoidance and information seeking among parents of children diagnosed with autism spectrum disorder (ASD) on age of diagnosis. An online survey was completed by 1,815 parents of children with ASD. Children of parents who self-reported that they had preferred "not to know," reported diagnoses around 3 months later than other children. Children of parents who raised concerns that they perceived as having been dealt with adequately reported diagnoses about 4 months earlier, but the children of parents who reported raising concerns repeatedly and felt that those concerns were dealt with inadequately were diagnosed over a year later. These findings suggest that failure of educational and healthcare professionals, in either substituting for parents who avoid information, or supporting those who seek information, can significantly delay the age of diagnosis.
MeSH term(s)	Autism Spectrum Disorder ; Child ; Educational Status ; Humans ; Information Seeking Behavior ; Parents ; Surveys and Questionnaires
Language	English
Publishing date	2021-06-09
Publishing country	United States
Document type	Journal Article
ZDB-ID	2477909-X
ISSN	1944-7558 ; 1944-7515
ISSN (online)	1944-7558
ISSN	1944-7515
DOI	10.1352/1944-7558-126.3.249
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Article ; Online: The management of severe rigid tuberculous kyphosis of the lumbar spine with multilevel vertebral column resection.

Kiely, Paul D / Boachie-Adjei, Oheneba / Kim, Han Jo

The spine journal : official journal of the North American Spine Society

2015 Volume 15, Issue 10, Page(s) e21–4

MeSH term(s)	Humans ; Kyphosis/diagnosis ; Kyphosis/surgery ; Lumbar Vertebrae/surgery ; Male ; Neurosurgical Procedures/adverse effects ; Tuberculosis, Spinal/diagnosis ; Tuberculosis, Spinal/surgery ; Young Adult
Language	English
Publishing date	2015-10-01
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	2037072-6
ISSN	1878-1632 ; 1529-9430
ISSN (online)	1878-1632
ISSN	1529-9430
DOI	10.1016/j.spinee.2015.05.024
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Article: Lactobacillus gasseri

Quigley, Lisa / Coakley, Mairéad / Alemayehu, Debebe / Rea, Mary C / Casey, Patrick G / O'Sullivan, Órla / Murphy, Eileen / Kiely, Barry / Cotter, Paul D / Hill, Colin / Ross, R Paul

Frontiers in microbiology

2019 Volume 10, Page(s) 273

Abstract: Clostridium ... ...

Abstract	Clostridium difficile
Language	English
Publishing date	2019-02-20
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2587354-4
ISSN	1664-302X
ISSN	1664-302X
DOI	10.3389/fmicb.2019.00273
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Article ; Online: Effect of Ultraviolet Light-Exposed Mushrooms on Vitamin D Status: Liquid Chromatography-Tandem Mass Spectrometry Reanalysis of Biobanked Sera from a Randomized Controlled Trial and a Systematic Review plus Meta-Analysis.

Cashman, Kevin D / Kiely, Mairead / Seamans, Kelly M / Urbain, Paul

The Journal of nutrition

2016 Volume 146, Issue 3, Page(s) 565–575

Abstract: ... hydroxyvitamin D [25(OH)D] in healthy participants consuming UV light-exposed edible mushrooms are limited and ... of serum 25(OH)D [and serum 25-hydroxyergocalciferol, 25(OH)D2, and serum 25-hydroxycholecalciferol, 25(OH ... for RCTs of UV-exposed mushrooms and data on serum 25(OH)D. Studies were screened for eligibility, and ...

Abstract	Background: Randomized controlled trial (RCT) data on the response of serum total 25-hydroxyvitamin D [25(OH)D] in healthy participants consuming UV light-exposed edible mushrooms are limited and mixed. Objective: The objective was to undertake a systematic review and meta-analysis of responses of serum 25(OH)D [and serum 25-hydroxyergocalciferol, 25(OH)D2, and serum 25-hydroxycholecalciferol, 25(OH)D3, if available] to consumption of UV-exposed mushrooms by healthy participants. Biobanked sera from one RCT (originally analyzed by immunoassay) were reanalyzed by LC-MS/MS to generate serum 25(OH)D2 and serum 25(OH)D3 data. Methods: Ovid MEDLINE, EMBASE, and Cochrane CENTRAL were searched for RCTs of UV-exposed mushrooms and data on serum 25(OH)D. Studies were screened for eligibility, and relevant data were extracted. Serum 25(OH)D data were re-analyzed by ANOVA and paired t tests. Results: Our structured search yielded 6 RCTs meeting our inclusion criteria. Meta-analysis of all 6 RCTs showed serum 25(OH)D was not significantly increased (P = 0.12) by UV-exposed mushrooms, but there was high heterogeneity (I(2) = 87%). Including only the 3 European-based RCTs [mean baseline 25(OH)D, 38.6 nmol/L], serum 25(OH)D was increased significantly by UV-exposed mushrooms [weighted mean difference (WMD): 15.2 nmol/L; 95% CI: 1.5, 28.8 nmol/L, P = 0.03, I(2) = 88%], whereas there was no significant effect in the 3 US-based RCTs [P = 0.83; mean baseline 25(OH)D: 81.5 nmol/L]. Analysis of serum 25(OH)D2 and serum 25(OH)D3 (n = 5 RCTs) revealed a statistically significant increase (WMD: 20.6 nmol/L; 95% CI: 8.0, 33.3 nmol/L, P = 0.001, I(2 =) 99%) and decrease (WMD: -13.3 nmol/L; 95% CI: -15.8, -10.7 nmol/L, P < 0.00001, I(2) = 0%) after supplementation with UV-exposed mushrooms. Conclusions: Consumption of UV-exposed mushrooms may increase serum 25(OH)D when baseline vitamin D status is low via an increase in 25(OH)D2 (24.2 nmol/L) and despite a concomitant but relatively smaller reduction in 25(OH)D3 (-12.6 nmol/L). When baseline vitamin D status is high, the mean increase in 25(OH)D2 (18.3 nmol/L) and a relatively similar reduction in 25(OH)D3 (-13.6 nmol/L) may explain the lack of effect on serum 25(OH)D.
MeSH term(s)	Agaricales/chemistry ; Agaricales/radiation effects ; Chromatography, Liquid ; Databases, Factual ; Humans ; Randomized Controlled Trials as Topic ; Tandem Mass Spectrometry ; Ultraviolet Rays ; Vitamin D/administration & dosage
Chemical Substances	Vitamin D (1406-16-2)
Language	English
Publishing date	2016-02-10
Publishing country	United States
Document type	Journal Article ; Meta-Analysis ; Research Support, Non-U.S. Gov't ; Review ; Systematic Review
ZDB-ID	218373-0
ISSN	1541-6100 ; 0022-3166
ISSN (online)	1541-6100
ISSN	0022-3166
DOI	10.3945/jn.115.223784
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Article ; Online: Clinical signs associated with earlier diagnosis of children with autism Spectrum disorder.

Sicherman, Nachum / Charite, Jimmy / Eyal, Gil / Janecka, Magdalena / Loewenstein, George / Law, Kiely / Lipkin, Paul H / Marvin, Alison R / Buxbaum, Joseph D

BMC pediatrics

2021 Volume 21, Issue 1, Page(s) 96

Abstract: Background: The objective of this study is to gain new insights into the relationship between clinical signs and age at diagnosis.: Method: We utilize a new, large, online survey of 1743 parents of children diagnosed with ASD, and use multiple ... ...

Abstract	Background: The objective of this study is to gain new insights into the relationship between clinical signs and age at diagnosis. Method: We utilize a new, large, online survey of 1743 parents of children diagnosed with ASD, and use multiple statistical approaches. These include regression analysis, factor analysis, and machine learning (regression tree). Results: We find that clinical signs that most strongly predict early diagnosis are not necessarily specific to autism, but rather those that initiate the process that eventually leads to an ASD diagnosis. Given the high correlations between symptoms, only a few signs are found to be important in predicting early diagnosis. For several clinical signs we find that their presence and intensity are positively correlated with delayed diagnosis (e.g., tantrums and aggression). Even though our data are drawn from parents' retrospective accounts, we provide evidence that parental recall bias and/or hindsight bias did not play a significant role in shaping our results. Conclusion: In the subset of children without early deficits in communication, diagnosis is delayed, and this might be improved if more attention will be given to clinical signs that are not necessarily considered as ASD symptoms. Our findings also suggest that careful attention should be paid to children showing excessive tantrums or aggression, as these behaviors may interfere with an early ASD diagnoses.
MeSH term(s)	Autism Spectrum Disorder/diagnosis ; Child ; Communication ; Early Diagnosis ; Humans ; Parents ; Retrospective Studies
Language	English
Publishing date	2021-02-25
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2041342-7
ISSN	1471-2431 ; 1471-2431
ISSN (online)	1471-2431
ISSN	1471-2431
DOI	10.1186/s12887-021-02551-0
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Article ; Online: Remission vs low disease activity: function, quality of life and structural outcomes in the Early Rheumatoid Arthritis Study and Network.

Nikiphorou, Elena / Norton, Sam J / Carpenter, Lewis / Walsh, David A / Creamer, Paul / Dixey, Josh / Young, Adam / Kiely, Patrick D W

Rheumatology (Oxford, England)

2019 Volume 59, Issue 6, Page(s) 1272–1280

Abstract: Objectives: To examine associations between function, quality of life and structural outcomes in patients achieving remission vs low disease activity in early RA.: Methods: Demographic, clinical and radiographic variables were collected at baseline ... ...

Abstract	Objectives: To examine associations between function, quality of life and structural outcomes in patients achieving remission vs low disease activity in early RA. Methods: Demographic, clinical and radiographic variables were collected at baseline and then annually from the Early Rheumatoid Arthritis Study (ERAS) and Early Rheumatoid Arthritis Network (ERAN) inception cohorts in routine care from 1986 to 2012. Disease activity was categorized: mean DAS28 score between years 1 and 5: remission [mean remission DAS (mRDAS) <2.6] or low [mean low DAS (mLDAS) 2.6-3.2]; sustained low/remission DAS28 (sLDAS/sRDAS) at years 1 and 2; and sustained Boolean remission (sBR) at years 1 and 2. Changes in HAQ and Short Form 36 Health Survey Questionnaire [SF-36; physical (PCS) and mental (MCS) component score]) and total Sharp van der Heijde (SvdH) scores for each disease activity category were modelled using multi-level models. Covariates included year of onset, age, gender and DMARD use at first visit. Results: Of 2701 patients, 562 (21%) were categorized mRDAS, 330 (12%) mLDAS, 279 (10%) sRDAS, 203 (7.5%) sLDAS and 93 (3%) sBR. Patients categorized as mRDAS had increasingly divergent improved HAQ, SF-36 PCS, MCS and total SvdH scores compared with mLDAS (P-values 0.001 to <0.0001, all time points). Patients categorized as sRDAS had better HAQ, SF-36 PCS and MCS scores (P-values 0.05 to <0.0001, all time points) and SvdH scores (P = 0.05, years 3-5) over sLDAS. sBR was associated with better HAQ, and SF-36 PCS and MCS scores over sLDAS (P-values 0.002 to <0.0001, all time points). Conclusion: These findings from routine care support ACR/EULAR guidelines that remission is a preferable goal over low disease activity in early RA.
MeSH term(s)	Adult ; Antirheumatic Agents/therapeutic use ; Arthritis, Rheumatoid/diagnosis ; Arthritis, Rheumatoid/drug therapy ; Arthritis, Rheumatoid/psychology ; Disease Progression ; Female ; Humans ; Male ; Middle Aged ; Quality of Life/psychology ; Remission Induction ; Severity of Illness Index
Chemical Substances	Antirheumatic Agents
Language	English
Publishing date	2019-10-02
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1464822-2
ISSN	1462-0332 ; 1462-0324
ISSN (online)	1462-0332
ISSN	1462-0324
DOI	10.1093/rheumatology/kez461
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