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  1. Article ; Online: Ectopic Salivary Glands - a Differential Diagnosis to a Thyroglossal Duct Cyst.

    Menter, Thomas / Holland-Cunz, Stefan

    Fetal and pediatric pathology

    2024  Volume 43, Issue 1, Page(s) 79–81

    Abstract: ... ...

    Abstract Background
    MeSH term(s) Female ; Humans ; Child, Preschool ; Thyroglossal Cyst/diagnosis ; Thyroglossal Cyst/pathology ; Thyroglossal Cyst/surgery ; Diagnosis, Differential ; Salivary Glands/pathology ; Thyroid Gland/pathology ; Thyroid Gland/surgery ; Neck/pathology
    Language English
    Publishing date 2024-01-24
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 2165508-X
    ISSN 1551-3823 ; 1551-3815 ; 1522-7952
    ISSN (online) 1551-3823
    ISSN 1551-3815 ; 1522-7952
    DOI 10.1080/15513815.2023.2266035
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2043: Show issues Location:
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  2. Article ; Online: Ectopic Salivary Gland - A Possible Differential Diagnosis of a Branchial Cleft Cyst.

    Menter, Thomas / Holland-Cunz, Stefan

    Fetal and pediatric pathology

    2023  Volume 42, Issue 4, Page(s) 706–708

    Abstract: Background: ...

    Abstract Background:
    MeSH term(s) Male ; Humans ; Child ; Branchioma/diagnosis ; Branchioma/pathology ; Branchioma/surgery ; Diagnosis, Differential ; Salivary Glands/pathology ; Neck/pathology
    Language English
    Publishing date 2023-03-29
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 2165508-X
    ISSN 1551-3823 ; 1551-3815 ; 1522-7952
    ISSN (online) 1551-3823
    ISSN 1551-3815 ; 1522-7952
    DOI 10.1080/15513815.2023.2193847
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2043: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  3. Article ; Online: CD23-positive, BCL2-Rearrangement-negative Keimzentrumslymphome.

    Menter, Thomas / Quintanilla-Martinez, Leticia

    Pathologie (Heidelberg, Germany)

    2023  Volume 44, Issue Suppl 3, Page(s) 160–163

    Abstract: Acknowledgeing that the group of follicular lymphomas is to be regarded as very heterogeneous, a group of follicular lymphomas has been delineated in recent years that was characterised by an often diffuse growth (without formation of evident follicular ... ...

    Title translation CD23 positive, BCL2 rearrangement-negative germinal centre lymphomas.
    Abstract Acknowledgeing that the group of follicular lymphomas is to be regarded as very heterogeneous, a group of follicular lymphomas has been delineated in recent years that was characterised by an often diffuse growth (without formation of evident follicular structures) as well as expression of CD23 in the lymphoma cells and the absence of the classic BCL2 translocation. Further characteristics are a preferred inguinal localisation of the lymphomas and a localised stage with a good prognosis. Genetically, this lymphoma group is characterised by a high rate of either STAT6 or SOCS1 mutations.The ICC classification took this development into account by introducing the provisional entity CD23 positive, BCL2 rearrangement-negative germinal centre lymphoma. Further studies must now show how exactly this entity can be defined (combination of morphology, immunohistochemical phenotype, focus on genetic alterations) in order to pave the way towards a uniform classification and a better clinical characterisation of these cases - especially with regard to possible new therapeutic treatment options.
    MeSH term(s) Humans ; Lymphoma, Follicular/diagnosis ; Proto-Oncogene Proteins c-bcl-2/genetics ; Germinal Center/metabolism ; Translocation, Genetic/genetics ; Mutation
    Chemical Substances Proto-Oncogene Proteins c-bcl-2 ; BCL2 protein, human
    Language German
    Publishing date 2023-11-06
    Publishing country Germany
    Document type English Abstract ; Journal Article ; Review
    ISSN 2731-7196
    ISSN (online) 2731-7196
    DOI 10.1007/s00292-023-01250-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Tumor Microenvironment in Acute Myeloid Leukemia: Adjusting Niches.

    Menter, Thomas / Tzankov, Alexandar

    Frontiers in immunology

    2022  Volume 13, Page(s) 811144

    Abstract: Acute myeloid leukemias (AML) comprise a wide array of different entities, which have in common a rapid expansion of myeloid blast cells leading to displacement of normal hematopoietic cells and also disruption of the microenvironment in the bone marrow ... ...

    Abstract Acute myeloid leukemias (AML) comprise a wide array of different entities, which have in common a rapid expansion of myeloid blast cells leading to displacement of normal hematopoietic cells and also disruption of the microenvironment in the bone marrow niches. Based on an insight into the complex cellular interactions in the bone marrow niches in non-neoplastic conditions in general, this review delineates the complex relationship between leukemic cells and reactive cells of the tumor microenvironment (TME) in AML. A special focus is directed on niche cells and various T-cell subsets as these also provide a potential therapeutic rationale considering e.g. immunomodulation. The TME of AML on the one hand plays a vital role for sustaining and promoting leukemogenesis but - on the other hand - it also has adverse effects on abnormal blasts developing into overt leukemia hindering their proliferation and potentially removing such cells. Thus, leukemic cells need to and develop strategies in order to manipulate the TME. Interference with those strategies might be of particular therapeutic potential since mechanisms of resistance related to tumor cell plasticity do not apply to it.
    MeSH term(s) Bone Marrow/pathology ; Bone Marrow Cells/pathology ; Humans ; Leukemia, Myeloid, Acute/pathology ; Stem Cell Niche ; Tumor Microenvironment
    Language English
    Publishing date 2022-02-22
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2022.811144
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: [No title information]

    Bornstein, Michael M / Schriber, Martina / Menter, Thomas

    Swiss dental journal

    2023  Volume 133, Issue 6, Page(s) 382–383

    Title translation Orale Retentions- und Extravasationsmukozelen der kleinen Speicheldrüsen – öfter, als man denkt!
    MeSH term(s) Humans ; Mucocele ; Salivary Glands, Minor ; Lasers, Gas ; Carbon Dioxide ; Treatment Outcome
    Chemical Substances Carbon Dioxide (142M471B3J)
    Language German
    Publishing date 2023-06-05
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2754538-6
    ISSN 2296-6498
    ISSN 2296-6498
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ul III Zs.43: Show issues Location:
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  6. Article ; Online: Klassifikation aggressiver B-Zell-Lymphome : Neuigkeiten und offene Fragen.

    Rosenwald, Andreas / Menter, Thomas / Dirnhofer, Stefan

    Pathologie (Heidelberg, Germany)

    2023  Volume 44, Issue 3, Page(s) 166–172

    Abstract: The 5th edition of the WHO classification (WHO-HAEM5) and the International Consensus Classification (ICC) show a broad consensus in the categorization of aggressive, large B‑cell lymphomas with expected minor impact only on the daily diagnostic routine. ...

    Title translation Classification of aggressive B-cell lymphomas : News and open questions.
    Abstract The 5th edition of the WHO classification (WHO-HAEM5) and the International Consensus Classification (ICC) show a broad consensus in the categorization of aggressive, large B‑cell lymphomas with expected minor impact only on the daily diagnostic routine. The changes compared to the 2017 revised WHO-HAEM4R are moderate and include updated names of entities, sharpened diagnostic criteria, and upgrades from provisional to definite entities. The definition of the most common aggressive B‑cell lymphoma, diffuse large B‑cell lymphoma (DLBCL), not otherwise specified (NOS), remains unchanged, and both classifications strongly encourage subtyping into germinal center B‑like (GCB) or the activated B‑like (ABC or non-GCB) DLBCL. DLBCL, NOS, should be separated from other large B‑cell lymphomas including large B‑cell lymphoma with IRF4 rearrangement (upgraded to a definite entity in both classifications) and large-cell/high-grade B‑cell lymphomas with 11q aberration. Aggressive B‑cell lymphomas with MYC and BCL2 rearrangements form a molecularly distinct group and are listed as definite entities in both classifications. This is in contrast to the more heterogeneous group of aggressive B‑cell lymphomas with MYC and BCL6 rearrangements that are recognized as a provisional entity in the ICC, while they fall into the DLBCL, NOS, or the HGBL, NOS, groups in the WHO-HAEM5.
    MeSH term(s) Humans ; Lymphoma, Large B-Cell, Diffuse/diagnosis ; Gene Rearrangement ; Germinal Center/pathology ; Chromosome Aberrations ; In Situ Hybridization, Fluorescence
    Language German
    Publishing date 2023-03-14
    Publishing country Germany
    Document type English Abstract ; Journal Article ; Review
    ISSN 2731-7196
    ISSN (online) 2731-7196
    DOI 10.1007/s00292-023-01187-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Renal Disease in Cryoglobulinemia.

    Menter, Thomas / Hopfer, Helmut

    Glomerular diseases

    2021  Volume 1, Issue 2, Page(s) 92–104

    Abstract: Background: Renal disease in cryoglobulinemia is difficult to grasp and diagnose because it is rare, serological testing is challenging and prone to artifacts, and its morphology is shared by other renal diseases resulting in a spectrum of differential ... ...

    Abstract Background: Renal disease in cryoglobulinemia is difficult to grasp and diagnose because it is rare, serological testing is challenging and prone to artifacts, and its morphology is shared by other renal diseases resulting in a spectrum of differential diagnoses. On occasion, a definitive diagnosis cannot even be rendered after immunofluorescence and electron microscopic studies.
    Summary: Based on kidney biopsies seen in our routine diagnostic and referral practice, we discuss and illustrate various morphological patterns of renal injury associated with cryoglobulins. We outline key pathophysiologic and clinical aspects associated with cryoglobulinemia induced renal disease and describe morphologic changes with a focus on electron microscopy. We present our practical, morphology-based approach to diagnostic decision-making with special consideration of differential diagnoses and disease mimickers. Since cryoglobulins are rarely tested for prior to kidney biopsy, pathologists and clinicians alike must have a high level of suspicion when interpreting renal biopsies and managing patients.
    Key messages: Cryoglobulinemia-associated glomerulonephritis (GN) is a multifactorial disease which is important to recognize for clinical practice. Morphological features suggestive of cryoglobulinemia-associated GN include a pattern of membranoproliferative GN with abundance of monocytes and the presence of (pseudo)thrombi. By electron microscopy, the main diagnostic features are a prominent infiltration of monocytes/macrophages and the presence of mesangial and subendothelial deposits with frequently curved microtubular/cylindrical and annular substructures.
    Language English
    Publishing date 2021-05-19
    Publishing country Switzerland
    Document type Journal Article ; Review
    ISSN 2673-3633
    ISSN (online) 2673-3633
    DOI 10.1159/000516103
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Differenzialdiagnose reaktiver Zytopenien.

    Menter, Thomas / Dirnhofer, Stefan / Tzankov, Alexandar

    Pathologie (Heidelberg, Germany)

    2022  Volume 43, Issue 4, Page(s) 263–270

    Abstract: Reactive cytopenias are a frequent cause for bone marrow investigations, including bone marrow trephine biopsies, especially if clinical examination and laboratory analyses (e.g., detection of substrate deficiencies) cannot provide a sufficient ... ...

    Title translation Differential diagnosis of reactive cytopenias.
    Abstract Reactive cytopenias are a frequent cause for bone marrow investigations, including bone marrow trephine biopsies, especially if clinical examination and laboratory analyses (e.g., detection of substrate deficiencies) cannot provide a sufficient explanation. The evaluation of such biopsies is primarily concerned with the exclusion of diseases that displace the normal hematopoiesis (infiltrates of acute leukemias or lymphomas and metastases), the exclusion of a myelodysplastic syndrome that classically results in ineffective hematopoiesis, or the detection of specific diseases, particularly infectious or histiocytic diseases (e.g., hemophagocytic lymphohistiocytosis).In this review, we describe characteristic morphologic changes of reactive cytopenias, focus on specific infectious and noninfectious clinical pictures, and distinguish them from malignant changes, especially myelodysplastic syndrome and underlying leukemia of large granular T lymphocytes. Drug-induced changes in hematopoiesis are described in another article in this issue.
    MeSH term(s) Bone Marrow/pathology ; Bone Marrow Examination ; Diagnosis, Differential ; Humans ; Myelodysplastic Syndromes/diagnosis ; Thrombocytopenia/diagnosis
    Language German
    Publishing date 2022-05-19
    Publishing country Germany
    Document type Journal Article ; Review
    ISSN 2731-7196
    ISSN (online) 2731-7196
    DOI 10.1007/s00292-022-01076-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Investigations of Pathologists as a Key to Understanding Coronavirus Disease 2019.

    Menter, Thomas / Tzankov, Alexandar

    Pathobiology : journal of immunopathology, molecular and cellular biology

    2020  Volume 88, Issue 1, Page(s) 11–14

    MeSH term(s) Belgium ; COVID-19 ; Early Detection of Cancer ; Humans ; Neoplasms ; Pandemics ; Pathologists ; Pathology, Surgical ; SARS-CoV-2
    Language English
    Publishing date 2020-12-18
    Publishing country Switzerland
    Document type Editorial ; Comment
    ZDB-ID 1022703-9
    ISSN 1423-0291 ; 1015-2008
    ISSN (online) 1423-0291
    ISSN 1015-2008
    DOI 10.1159/000513602
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Nasal glial heterotopia: a systematic review of the literature and case report.

    Gallego Compte, Montserrat / Menter, Thomas / Guertler, Nicolas / Negoias, Simona

    Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale

    2022  Volume 42, Issue 4, Page(s) 317–324

    MeSH term(s) Diagnosis, Differential ; Humans ; Magnetic Resonance Imaging ; Nose Diseases/diagnosis ; Nose Neoplasms/diagnosis
    Language English
    Publishing date 2022-10-18
    Publishing country Italy
    Document type Case Reports ; Journal Article ; Review ; Systematic Review
    ZDB-ID 604898-5
    ISSN 1827-675X ; 0392-100X
    ISSN (online) 1827-675X
    ISSN 0392-100X
    DOI 10.14639/0392-100X-N1977
    Database MEDical Literature Analysis and Retrieval System OnLINE

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