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  1. Article ; Online: Circ_0030042 inhibits trophoblast cell growth, invasion and epithelial-mesenchymal transition process in preeclampsia via miR-942-5p/LITAF.

    Tian, Xiaolong / Zhang, Yajun / Zhao, Meng / Yin, Xiaofang

    Journal of reproductive immunology

    2024  Volume 162, Page(s) 104205

    Abstract: Background: There is increasing evidence that circular RNAs (circRNAs) are involved in the processes of preeclampsia (PE). Circ_0030042 was found to be abnormally expressed in PE patients. However, the role and molecular mechanism of circ_0030042 in PE ... ...

    Abstract Background: There is increasing evidence that circular RNAs (circRNAs) are involved in the processes of preeclampsia (PE). Circ_0030042 was found to be abnormally expressed in PE patients. However, the role and molecular mechanism of circ_0030042 in PE progression remains unclear.
    Methods: Quantitative real-time PCR was used for determining the expression of circ_0030042, microRNA (miR)- 942-5p and lipopolysaccharide induced TNF-α factor (LITAF). Trophoblast cell functions were determined using cell counting kit 8 assay, EdU assay, flow cytometry and transwell assay. The protein levels of epithelial-mesenchymal transition (EMT)-related markers and LITAF were examined using western blot analysis. Dual-luciferase reporter assay and RNA pull-down assay were used to verify RNA interaction.
    Results: Circ_0030042 had an elevated expression in PE patients, and its overexpression inhibited trophoblast cell growth, invasion, and EMT process. Circ_0030042 served as miR-942-5p sponge, and miR-942-5p inhibitor also reversed the regulation of circ_0030042 on trophoblast cell growth, invasion and EMT process. LITAF was targeted by miR-942-5p, and its knockdown abolished the inhibition effect of miR-942-5p on trophoblast cell growth, invasion, and EMT process. Also, circ_0030042 regulated LITAF expression via sponging miR-942-5p.
    Conclusion: Circ_0030042 regulated trophoblast cell growth, invasion, and EMT process via the miR-942-5p/LITAF axis, providing a novel insight for PE treatment.
    MeSH term(s) Female ; Humans ; Pregnancy ; Cell Movement ; Cell Proliferation ; Epithelial-Mesenchymal Transition/genetics ; Lipopolysaccharides ; MicroRNAs/genetics ; Nuclear Proteins ; Pre-Eclampsia/genetics ; Transcription Factors ; Trophoblasts ; Tumor Necrosis Factor-alpha ; RNA, Circular
    Chemical Substances Lipopolysaccharides ; LITAF protein, human ; MicroRNAs ; MIRN942 microRNA, human ; Nuclear Proteins ; Transcription Factors ; Tumor Necrosis Factor-alpha ; RNA, Circular
    Language English
    Publishing date 2024-01-17
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 424421-7
    ISSN 1872-7603 ; 0165-0378
    ISSN (online) 1872-7603
    ISSN 0165-0378
    DOI 10.1016/j.jri.2024.104205
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1483: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Investigation on low energy-consumed embedded selective catalytic reduction technology for pelletizing flue gas and the CO

    Tang, Hao / Liu, Xiaolong / Li, Yiren / Tian, Jinglei / Hou, Changjiang / Tian, Mengkui / Zhu, Tingyu

    Environmental science and pollution research international

    2023  Volume 30, Issue 18, Page(s) 53492–53504

    Abstract: Based on the unique technique property of grate-kiln pellet production process and its demand of ultra-low emission of ... ...

    Abstract Based on the unique technique property of grate-kiln pellet production process and its demand of ultra-low emission of NO
    MeSH term(s) Carbon Dioxide ; Temperature ; Cold Temperature ; Catalysis
    Chemical Substances Carbon Dioxide (142M471B3J)
    Language English
    Publishing date 2023-03-01
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-023-26042-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Corrigendum: Detection methods of nanoparticles synthesized by gas-phase method: a review.

    Zhang, Xiushuo / Zhao, Xiaolong / Li, Hongsheng / Hao, Xiaorui / Xu, Jing / Tian, Jingjing / Wang, Yong

    Frontiers in chemistry

    2023  Volume 11, Page(s) 1351829

    Abstract: This corrects the article DOI: 10.3389/fchem.2022.845363.]. ...

    Abstract [This corrects the article DOI: 10.3389/fchem.2022.845363.].
    Language English
    Publishing date 2023-12-14
    Publishing country Switzerland
    Document type Published Erratum
    ZDB-ID 2711776-5
    ISSN 2296-2646
    ISSN 2296-2646
    DOI 10.3389/fchem.2023.1351829
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Corrigendum

    Xiushuo Zhang / Xiaolong Zhao / Hongsheng Li / Xiaorui Hao / Jing Xu / Jingjing Tian / Yong Wang

    Frontiers in Chemistry, Vol

    Detection methods of nanoparticles synthesized by gas-phase method: a review

    2023  Volume 11

    Keywords gas-phase method ; nanoparticles ; detection methods ; review ; expectation ; Chemistry ; QD1-999
    Language English
    Publishing date 2023-12-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article: Exploring the Impact of Smartphone Addiction on Risk Decision-Making Behavior among College Students Based on fNIRS Technology.

    Liu, Xiaolong / Tian, Ruoyi / Liu, Huafang / Bai, Xue / Lei, Yi

    Brain sciences

    2023  Volume 13, Issue 9

    Abstract: Smartphone Addiction is a social issue caused by excessive smartphone use, affecting decision-making processes. Current research on the risky decision-making abilities of smartphone addicts is limited. This study used the functional Near-Infrared ... ...

    Abstract Smartphone Addiction is a social issue caused by excessive smartphone use, affecting decision-making processes. Current research on the risky decision-making abilities of smartphone addicts is limited. This study used the functional Near-Infrared Spectroscopy (fNIRS) brain imaging technique and a Sequential Risk-Taking Task experimental paradigm to investigate the decision-making behavior and brain activity of smartphone addicts under varying risk levels. Using a mixed experimental design, the research assessed decision-making ability and brain activation levels as dependent variables across two groups (addiction and control), two risk amounts (high and low), and two outcomes (gain and loss). The study included 42 participants, with 25 in the addiction group and 17 in the control group. Results indicated that risk level significantly impacted the decision-making ability of smartphone addicts, with high-risk levels leading to weaker decision-making ability and increased risk-taking. However, at low-risk levels, decision-making abilities between addicts and healthy individuals showed no significant difference. Furthermore, brain imaging results using fNIRS revealed stronger brain activation in the dorsolateral Prefrontal Cortex (dlPFC) region for smartphone addicts under loss outcome conditions, with no significant differences between the two groups in terms of brain activation at varying risk volumes. These findings are critical in promoting healthy smartphone use, guiding clinical treatment, and advancing brain mechanism research.
    Language English
    Publishing date 2023-09-15
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2651993-8
    ISSN 2076-3425
    ISSN 2076-3425
    DOI 10.3390/brainsci13091330
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Capillary-Driven Boiling Heat Transfer on Superwetting Microgrooves.

    Li, Yimin / Yang, Xiaolong / Tian, Xu / Tang, Yu

    ACS omega

    2022  Volume 7, Issue 39, Page(s) 35339–35350

    Abstract: Boiling can transfer a vast amount of heat and thereby is widely used for cooling advanced systems with high power density. However, the capillary force of most existing wicks is insufficient to surpass the liquid replenishing resistance for high- ... ...

    Abstract Boiling can transfer a vast amount of heat and thereby is widely used for cooling advanced systems with high power density. However, the capillary force of most existing wicks is insufficient to surpass the liquid replenishing resistance for high-efficient boiling. Herein, we report a new microgroove wick on high-conductive copper substrates that was constructed via ultraviolet nanosecond pulsed laser milling. The phase explosion, combined with melting and resolidification effects of laser milling induces dense microcavities with sizes around several micrometers on the microgroove surface. The hierarchical microstructures significantly improve the wettability of the microgroove wicks to obtain strong capillary and meanwhile provide abundant effective nucleation sites. The boiling heat transfer in a visualized flat heat pipe shows that the new wicks enable sustainable liquid replenishing even under antigravity conditions, thus resulting in maximum 33-fold improvement of equivalent thermal conductivity when compared with the copper base. This research provides both scientific and technical bases for the design and manufacture of high-performance phase change cooling devices.
    Language English
    Publishing date 2022-09-26
    Publishing country United States
    Document type Journal Article
    ISSN 2470-1343
    ISSN (online) 2470-1343
    DOI 10.1021/acsomega.2c05381
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Magnetic resonance/fluorescence dual-modality contrast agents targeting α

    Yin, Qiangqiang / Qi, Guiqiang / Wang, Shengchao / Tian, Hongda / Gao, Xiaolong / Zhang, Zhichen / Hao, Liguo

    Biochemical and biophysical research communications

    2023  Volume 664, Page(s) 86–93

    Abstract: Pancreatic ductal adenocarcinoma (PDAC) is a malignant digestive system tumor with a poor late-stage prognosis. This study aimed to identify new methods for the early detection of PDAC. The nanoprobe A20FMDV2-Gd-5-FAM was developed using A20FMDV2 ( ... ...

    Abstract Pancreatic ductal adenocarcinoma (PDAC) is a malignant digestive system tumor with a poor late-stage prognosis. This study aimed to identify new methods for the early detection of PDAC. The nanoprobe A20FMDV2-Gd-5-FAM was developed using A20FMDV2 (N
    MeSH term(s) Mice ; Animals ; Humans ; Contrast Media ; Fluorescent Dyes ; Ligands ; Mice, Nude ; Cell Line, Tumor ; Peptides/chemistry ; Pancreatic Neoplasms/diagnostic imaging ; Magnetic Resonance Imaging/methods ; Carcinoma, Pancreatic Ductal ; Magnetic Resonance Spectroscopy ; Pancreatic Neoplasms
    Chemical Substances Contrast Media ; Fluorescent Dyes ; Ligands ; Peptides
    Language English
    Publishing date 2023-04-27
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 205723-2
    ISSN 1090-2104 ; 0006-291X ; 0006-291X
    ISSN (online) 1090-2104 ; 0006-291X
    ISSN 0006-291X
    DOI 10.1016/j.bbrc.2023.04.071
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 116: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: Predicting Cancer Lymph-Node Metastasis From LncRNA Expression Profiles Using Local Linear Reconstruction Guided Distance Metric Learning.

    Li, Bo / Tian, Yihui / Tian, Yang / Zhang, Shihua / Zhang, Xiaolong

    IEEE/ACM transactions on computational biology and bioinformatics

    2022  Volume 19, Issue 6, Page(s) 3179–3189

    Abstract: Lymph-node metastasis is the most perilous cancer progressive state, where long non-coding RNA (lncRNA) has been confirmed to be an important genetic indicator in cancer prediction. However, lncRNA expression profile is often characterized of large ... ...

    Abstract Lymph-node metastasis is the most perilous cancer progressive state, where long non-coding RNA (lncRNA) has been confirmed to be an important genetic indicator in cancer prediction. However, lncRNA expression profile is often characterized of large features and small samples, it is urgent to establish an efficient judgment to deal with such high dimensional lncRNA data, which will aid in clinical targeted treatment. Thus, in this study, a local linear reconstruction guided distance metric learning is put forward to handle lncRNA data for determination of cancer lymph-node metastasis. In the original locally linear embedding (LLE) approach, any point can be approximately linearly reconstructed using its nearest neighborhood points, from which a novel distance metric can be learned by satisfying both nonnegative and sum-to-one constraints on the reconstruction weights. Taking the defined distance metric and lncRNA data supervised information into account, a local margin model will be deduced to find a low dimensional subspace for lncRNA signature extraction. At last, a classifier is constructed to predict cancer lymph-node metastasis, where the learned distance metric is also adopted. Several experiments on lncRNA data sets have been carried out, and experimental results show the performance of the proposed method by making comparisons with some other related dimensionality reduction methods and the classical classifier models.
    MeSH term(s) Humans ; RNA, Long Noncoding/genetics ; Lymphatic Metastasis/genetics ; Gene Expression Regulation, Neoplastic/genetics
    Chemical Substances RNA, Long Noncoding
    Language English
    Publishing date 2022-12-08
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1557-9964
    ISSN (online) 1557-9964
    DOI 10.1109/TCBB.2022.3149791
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: A research on promoting chemical fertiliser reduction for sustainable agriculture purposes: Evolutionary game analyses involving ‘government, farmers, and consumers’

    Tian, Mengling / Zheng, Yangyang / Sun, Xiaolong / Zheng, Haochi

    Ecological indicators. 2022 Nov., v. 144

    2022  

    Abstract: The excessive use of chemical fertilisers seriously worsened the agro-ecological environment in China. Despite the Chinese government enacted a series of policies to reduce chemical fertilisers use, the situation has not been significantly improved. ... ...

    Abstract The excessive use of chemical fertilisers seriously worsened the agro-ecological environment in China. Despite the Chinese government enacted a series of policies to reduce chemical fertilisers use, the situation has not been significantly improved. Existing researches about the fertiliser reduction mainly from a single subject, but farmers' chemical fertiliser use behaviour is jointly affected by multiple subjects, including farmers, market and government. To reduce chemical fertilisers use and realize the green and sustainable development of agriculture, this paper builds a tripartite evolution model of the government, farmers and consumers based on evolutionary game theory, and simulates and discusses the behaviour of the government, farmers and consumers in the process of fertiliser reduction. Results indicate: (1) Under different partnership modes, the tripartite of government, farmers and consumers can evolve to reach a stable state. (2) The government's ecological compensation for farmers’ fertiliser reduction and subsidies for consumers' green consumption are inadequate. Raising ecological compensation to 200%–267% of the original level could incentive farmers chemical fertiliser reduction. Raising the price subsidies for consumers’ green consumption to approximately 136% of the original level could help motivate farmers to make a green production transformation through the market mechanism. (3) Farmers' risk expectations of fertiliser reduction is negatively correlated with farmers' chemical fertilisers reduction willingness and consumers' green consumption willingness. Consumers’ trust is positively correlated with farmers' chemical fertilisers reduction willingness and consumers' green consumption willingness. This study provides theoretical guidance for the government, farmers and consumers in making scientific decisions, serving as a policy reference for the government to promote chemical fertiliser reduction.
    Keywords agroecology ; evolution ; fertilizer application ; game theory ; issues and policy ; markets ; models ; prices ; risk ; sustainable agriculture ; China
    Language English
    Dates of publication 2022-11
    Publishing place Elsevier Ltd
    Document type Article
    ZDB-ID 2036774-0
    ISSN 1872-7034 ; 1470-160X
    ISSN (online) 1872-7034
    ISSN 1470-160X
    DOI 10.1016/j.ecolind.2022.109433
    Database NAL-Catalogue (AGRICOLA)

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    Z 7436: Show issues

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  10. Article ; Online: Coaxial illumination module of the stimulated-emission-depletion nanoscope.

    Shi, Jintao / Yu, Jianqiang / Tian, Zhan / Kou, Xiaolong / Yang, Hongwei / Liu, Xiaolong / Yuan, Jinghe / Fang, Xiaohong

    Optics express

    2022  Volume 30, Issue 8, Page(s) 13481–13490

    Abstract: Stimulated-emission-depletion (STED) nanoscope achieves super-resolution imaging by using a donut-shaped depletion beam to darken the fluorophores around the excitation spot. As an important factor determining the resolution of imaging, the coaxiality ... ...

    Abstract Stimulated-emission-depletion (STED) nanoscope achieves super-resolution imaging by using a donut-shaped depletion beam to darken the fluorophores around the excitation spot. As an important factor determining the resolution of imaging, the coaxiality between the excitation and the depletion beam is required to be maintained at the nanoscale, which is often degraded by various interference such as ambient vibration and temperatures etc. Here, we propose a specially designed STED illumination module to guarantee the coaxiality between the two beams while modulating the phase of the depletion beam. This STED illumination module can realize phase modulation, polarization adjustment, pulse delay and two beams coaxial at the same time. With the experiments, the module can guarantee the two beams are stably coaxial for a long time. We imaged fluorescence particles with diameter 40 nm and got images of 40 nm full width at half maximum. Adjacent microfilaments at 80 nm being clearly distinguished with our STED nonoscope demonstrates that it could be well applied to biological samples.
    Language English
    Publishing date 2022-04-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1491859-6
    ISSN 1094-4087 ; 1094-4087
    ISSN (online) 1094-4087
    ISSN 1094-4087
    DOI 10.1364/OE.454350
    Database MEDical Literature Analysis and Retrieval System OnLINE

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