LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 23

Search options

  1. Article ; Online: Enhancing the Washing Durability and Electrical Longevity of Conductive Polyaniline-Grafted Polyester Fabrics.

    Aizamddin, Muhammad Faiz / Mahat, Mohd Muzamir

    ACS omega

    2023  Volume 8, Issue 41, Page(s) 37936–37947

    Abstract: The demand for wearable electronics has driven the development of conductive fabrics, particularly those incorporating polyaniline (PANI) that is known for its high electrical conductivity, flexibility, and ease of fabrication. However, the limited ... ...

    Abstract The demand for wearable electronics has driven the development of conductive fabrics, particularly those incorporating polyaniline (PANI) that is known for its high electrical conductivity, flexibility, and ease of fabrication. However, the limited stability and durability of the conductive fabric, especially during washing, present significant challenges. The drawbacks can be traced by weak physical attachment between the fabric and the conductive coating, leading to a decrease in conductivity over time. These drawbacks significantly impact the fabric's functionality and performance, highlighting the need for effective solutions to enhance its stability and durability. This study focuses on addressing these challenges by employing a thermochemical treatment. A hydrophilic surface of the polyester fabric is obtained after the treatment (hydrolysis), followed by grafting of PANI on it. The adhesion between PANI and the polyester fabrics was found to be enhanced, as proved by contact angle analysis. Furthermore, the PANI-hydrolyzed fabrics (treated) demonstrated stable conductivity (∼10
    Language English
    Publishing date 2023-10-03
    Publishing country United States
    Document type Journal Article
    ISSN 2470-1343
    ISSN (online) 2470-1343
    DOI 10.1021/acsomega.3c03377
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article ; Online: Electroreduction of dissolved carbon dioxide on roughened molybdenum microelectrodes.

    Yahya, Siti Hajjar / Al-Lolage, Firas A / Mahat, Mohd Muzamir / Ramli, Muhammad Zahir / Syamsul, Mohd / Falina, Shaili / Ahmad Ruzaidi, Dania Adila / Danial, Wan Hazman / Shafiee, Saiful Arifin

    RSC advances

    2023  Volume 13, Issue 47, Page(s) 32918–32926

    Abstract: The increasing levels of carbon dioxide ( ... ...

    Abstract The increasing levels of carbon dioxide (CO
    Language English
    Publishing date 2023-11-08
    Publishing country England
    Document type Journal Article
    ISSN 2046-2069
    ISSN (online) 2046-2069
    DOI 10.1039/d3ra05592b
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article ; Online: Antibacterial Performance of Protonated Polyaniline-Integrated Polyester Fabrics.

    Aizamddin, Muhammad Faiz / Mahat, Mohd Muzamir / Zainal Ariffin, Zaidah / Nawawi, Mohd Azizi / Jani, Nur Aimi / Nor Amdan, Nur Asyura / Sadasivuni, Kishor Kumar

    Polymers

    2022  Volume 14, Issue 13

    Abstract: During the last few years, there has been an increase in public awareness of antimicrobial fabrics, as well as an increase in commercial opportunities for their use in pharmaceutical and medical settings. The present study reports on the optimized ... ...

    Abstract During the last few years, there has been an increase in public awareness of antimicrobial fabrics, as well as an increase in commercial opportunities for their use in pharmaceutical and medical settings. The present study reports on the optimized fabrication of protonated polyaniline (PANI)-integrated polyester (PES) fabric.
    Language English
    Publishing date 2022-06-28
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527146-5
    ISSN 2073-4360 ; 2073-4360
    ISSN (online) 2073-4360
    ISSN 2073-4360
    DOI 10.3390/polym14132617
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article ; Online: Engineered liposomes mediated approach for targeted colorectal cancer drug Delivery: A review.

    Shazleen Ibrahim, Intan / Starlin Chellathurai, Melbha / Mahmood, Syed / Hakim Azmi, Amirul / Harun, Norsyifa / Ulul Ilmie Ahmad Nazri, Mohd / Muzamir Mahat, Mohd / Mohamed Sofian, Zarif

    International journal of pharmaceutics

    2023  Volume 651, Page(s) 123735

    Abstract: Colorectal cancer (CRC) continues to be one of the most prevalent and deadliest forms of cancer worldwide, despite notable advancements in its management. The prognosis for metastatic CRC remains discouraging, with a relative 5-year survival rate for ... ...

    Abstract Colorectal cancer (CRC) continues to be one of the most prevalent and deadliest forms of cancer worldwide, despite notable advancements in its management. The prognosis for metastatic CRC remains discouraging, with a relative 5-year survival rate for stage IV CRC patients. Conventional treatments for advanced malignancies such as chemotherapy, often face limitations in effectively targeting cancer cells resulting in off-target distribution and significant side effects. In the quest for better strategies, researchers have explored numerous alternatives. Among these, nanoparticles (NPs) specifically liposomes have emerged as one of the most promising candidates in developing targeted delivery systems for cancer therapeutics. This review discusses the current approaches employing functionalised liposomes to overcome major biological barriers in therapeutics delivery for CRC treatment. We have also shared our perspectives on the technological development of liposomes for future clinical use and highlighted a few useful insights on the material choices for future research work in CRC.
    MeSH term(s) Humans ; Liposomes/therapeutic use ; Drug Delivery Systems ; Nanoparticles ; Colorectal Neoplasms/drug therapy ; Colorectal Neoplasms/pathology ; Antineoplastic Agents
    Chemical Substances Liposomes ; Antineoplastic Agents
    Language English
    Publishing date 2023-12-22
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 428962-6
    ISSN 1873-3476 ; 0378-5173
    ISSN (online) 1873-3476
    ISSN 0378-5173
    DOI 10.1016/j.ijpharm.2023.123735
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Article: Fabrication Methods of Electroactive Scaffold-Based Conducting Polymers for Tissue Engineering Application: A Review.

    Asri, Nurul Ain Najihah / Mahat, Mohd Muzamir / Zakaria, Azlan / Safian, Muhd Fauzi / Abd Hamid, Umi Marshida

    Frontiers in bioengineering and biotechnology

    2022  Volume 10, Page(s) 876696

    Abstract: Conductive scaffolds, defined as scaffold systems capable of carrying electric current, have been extensively researched for tissue engineering applications. Conducting polymers (CPs) as components of conductive scaffolds was introduced to improve ... ...

    Abstract Conductive scaffolds, defined as scaffold systems capable of carrying electric current, have been extensively researched for tissue engineering applications. Conducting polymers (CPs) as components of conductive scaffolds was introduced to improve morphology or cell attachment, conductivity, tissue growth, and healing rate, all of which are beneficial for cardiac, muscle, nerve, and bone tissue management. Conductive scaffolds have become an alternative for tissue replacement, and repair, as well as to compensate for the global organ shortage for transplantation. Previous researchers have presented a wide range of fabrication methods for conductive scaffolds. This review highlights the most recent advances in developing conductive scaffolds, with the aim to trigger more theoretical and experimental work to address the challenges and prospects of these new fabrication techniques in medical sciences.
    Language English
    Publishing date 2022-07-07
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2719493-0
    ISSN 2296-4185
    ISSN 2296-4185
    DOI 10.3389/fbioe.2022.876696
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  6. Article ; Online: Application of Conductive Hydrogels on Spinal Cord Injury Repair: A Review.

    Shahemi, Nur Hidayah / Mahat, Mohd Muzamir / Asri, Nurul Ain Najihah / Amir, Muhammad Abid / Ab Rahim, Sharaniza / Kasri, Mohamad Arif

    ACS biomaterials science & engineering

    2023  Volume 9, Issue 7, Page(s) 4045–4085

    Abstract: Spinal cord injury (SCI) causes severe motor or sensory damage that leads to long-term disabilities due to disruption of electrical conduction in neuronal pathways. Despite current clinical therapies being used to limit the propagation of cell or tissue ... ...

    Abstract Spinal cord injury (SCI) causes severe motor or sensory damage that leads to long-term disabilities due to disruption of electrical conduction in neuronal pathways. Despite current clinical therapies being used to limit the propagation of cell or tissue damage, the need for neuroregenerative therapies remains. Conductive hydrogels have been considered a promising neuroregenerative therapy due to their ability to provide a pro-regenerative microenvironment and flexible structure, which conforms to a complex SCI lesion. Furthermore, their conductivity can be utilized for noninvasive electrical signaling in dictating neuronal cell behavior. However, the ability of hydrogels to guide directional axon growth to reach the distal end for complete nerve reconnection remains a critical challenge. In this Review, we highlight recent advances in conductive hydrogels, including the incorporation of conductive materials, fabrication techniques, and cross-linking interactions. We also discuss important characteristics for designing conductive hydrogels for directional growth and regenerative therapy. We propose insights into electrical conductivity properties in a hydrogel that could be implemented as guidance for directional cell growth for SCI applications. Specifically, we highlight the practical implications of recent findings in the field, including the potential for conductive hydrogels to be used in clinical applications. We conclude that conductive hydrogels are a promising neuroregenerative therapy for SCI and that further research is needed to optimize their design and application.
    MeSH term(s) Humans ; Hydrogels/therapeutic use ; Hydrogels/chemistry ; Spinal Cord Injuries/drug therapy ; Spinal Cord Injuries/pathology ; Nerve Regeneration ; Electric Conductivity
    Chemical Substances Hydrogels
    Language English
    Publishing date 2023-06-26
    Publishing country United States
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ISSN 2373-9878
    ISSN (online) 2373-9878
    DOI 10.1021/acsbiomaterials.3c00194
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  7. Article ; Online: Mechanical and Structural Properties of Polyhydroxybutyrate as Additive in Blend Material in Additive Manufacturing for Medical Applications.

    Zainuddin, Muhammad Zulhilmi / Abu Bakar, Ahmad Adnan / Adam, Ahmad Nurhelmy / Abdullah, Shahino Mah / Tamchek, Nizam / Alauddin, Muhammad Syafiq / Mahat, Mohd Muzamir / Wiwatcharagoses, Nophadon / Alforidi, Ahmad / Ghazali, Mohd Ifwat Mohd

    Polymers

    2023  Volume 15, Issue 8

    Abstract: Today, additive manufacturing (AM) is considered one of the vital tenets of the industry 4.0 revolution due to its high productivity, decentralized production and rapid prototyping. This work aims to study the mechanical and structural properties of ... ...

    Abstract Today, additive manufacturing (AM) is considered one of the vital tenets of the industry 4.0 revolution due to its high productivity, decentralized production and rapid prototyping. This work aims to study the mechanical and structural properties of polyhydroxybutyrate as an additive in blend materials and its potential in medical applications. PHB/PUA blend resins were formulated with 0 wt.%, 6 wt.%, 12 wt.% and 18 wt.% of PHB concentration. Stereolithography or an SLA 3D printing technique were used to evaluate the printability of the PHB/PUA blend resins. Additionally, from FESEM analysis, a change was observed in PUA's microstructure, with an additional number of voids spotted. Furthermore, from XRD analysis, as PHB concentration increased, the crystallinity index (CI) also increased. This indicates the brittleness properties of the materials, which correlated to the weak performance of the tensile and impact properties. Next, the effect of PHB loading concentration within PHB/PUA blends and aging duration towards the mechanical performance of tensile and impact properties was also studied by using analysis of variance (ANOVA) with a two-way method. Finally, 12 wt.% of PHB/PUA was selected to 3D print the finger splint due to its characteristics, which are compatible to be used in finger bone fracture recovery.
    Language English
    Publishing date 2023-04-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527146-5
    ISSN 2073-4360 ; 2073-4360
    ISSN (online) 2073-4360
    ISSN 2073-4360
    DOI 10.3390/polym15081849
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  8. Article ; Online: Synthesis, Characterisation and Antibacterial Properties of Silicone-Silver Thin Film for the Potential of Medical Device Applications.

    Aizamddin, Muhammad Faiz / Mahat, Mohd Muzamir / Zainal Ariffin, Zaidah / Samsudin, Irwan / Razali, Muhammad Syafiek Mohd / Amir, Muhammad 'Abid

    Polymers

    2021  Volume 13, Issue 21

    Abstract: Silver (Ag) particles have sparked considerable interest in industry and academia, particularly for health and medical applications. Here, we present the "green" and simple synthesis of an Ag particle-based silicone (Si) thin film for medical device ... ...

    Abstract Silver (Ag) particles have sparked considerable interest in industry and academia, particularly for health and medical applications. Here, we present the "green" and simple synthesis of an Ag particle-based silicone (Si) thin film for medical device applications. Drop-casting and peel-off techniques were used to create an Si thin film containing 10-50% (
    Language English
    Publishing date 2021-11-05
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527146-5
    ISSN 2073-4360 ; 2073-4360
    ISSN (online) 2073-4360
    ISSN 2073-4360
    DOI 10.3390/polym13213822
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  9. Article ; Online: Potential Applications of Conducting Polymers to Reduce Secondary Bacterial Infections among COVID-19 Patients: a Review.

    Mahat, Mohd Muzamir / Sabere, Awis Sukarni Mohmad / Azizi, Juzaili / Amdan, Nur Asyura Nor

    Emergent materials

    2021  Volume 4, Issue 1, Page(s) 279–292

    Abstract: The COVID-19 pandemic is a motivation for material scientists to search for functional materials with valuable properties to alleviate the risks associated with the coronavirus. The formulation of functional materials requires synergistic understanding ... ...

    Abstract The COVID-19 pandemic is a motivation for material scientists to search for functional materials with valuable properties to alleviate the risks associated with the coronavirus. The formulation of functional materials requires synergistic understanding on the properties of materials and mechanisms of virus transmission and disease progression, including secondary bacterial infections that are prevalent in COVID-19 patients. A viable candidate in the struggle against the pandemic is antimicrobial polymer, due to their favorable properties of flexibility, lightweight, and ease of synthesis. Polymers are the base material for personal protective equipment (PPE), such as gloves, face mask, face shield, and coverall suit for frontliners. Conducting polymers (CPs) are polymers with electrical properties due to the addition of dopant in the polymer structure. The conductivity of polymers augments their antiviral and antibacterial properties. This review discusses the types of CPs and how their properties could be exploited to ward off bacterial infections in hospital settings, specifically in cases involving COVID-19 patients. This review also covers common CPs fabrication techniques. The key components to produce CPs at several possibilities to fit the current needs in fighting secondary bacterial infections are also discussed.
    Language English
    Publishing date 2021-02-24
    Publishing country Switzerland
    Document type Journal Article ; Review
    ISSN 2522-574X
    ISSN (online) 2522-574X
    DOI 10.1007/s42247-021-00188-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  10. Article ; Online: Investigating how amine structure influences drug-amine ion-pair formation and uptake via the polyamine transporter in A549 lung cells.

    Mohamed Sofian, Zarif / Harun, Norsyifa / Mahat, Mohd Muzamir / Nor Hashim, Nikman Adli / Jones, Stuart A

    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V

    2021  Volume 168, Page(s) 53–61

    Abstract: Transiently associating amines with therapeutic agents through the formation of ion-pairs has been established both in vitro and in vivo as an effective means to systemically direct drug delivery to the lung via the polyamine transport system (PTS). ... ...

    Abstract Transiently associating amines with therapeutic agents through the formation of ion-pairs has been established both in vitro and in vivo as an effective means to systemically direct drug delivery to the lung via the polyamine transport system (PTS). However, there remains a need to better understand the structural traits required for effective PTS uptake of drug ion-pairs. This study aimed to use a structurally related series of amine counterions to investigate how they influenced the stability of theophylline ion-pairs and their active uptake in A549 cells. Using ethylamine (mono-amine), ethylenediamine (di-amine), spermidine (tri-amine) and spermine (tetra-amine) as counterions the ion-pair affinity was shown to increase as the number of protonated amine groups in the counterion structure increased. The mono and diamines generated a single hydrogen bond and the weakest ion-pair affinities (pK
    MeSH term(s) A549 Cells ; Biological Transport ; Drug Delivery Systems ; Humans ; Hydrogen Bonding ; Lung/cytology ; Lung/metabolism ; Polyamines/chemistry ; Polyamines/metabolism ; Theophylline/metabolism
    Chemical Substances Polyamines ; Theophylline (C137DTR5RG)
    Language English
    Publishing date 2021-08-27
    Publishing country Netherlands
    Document type Comparative Study ; Journal Article
    ZDB-ID 1065368-5
    ISSN 1873-3441 ; 0939-6411
    ISSN (online) 1873-3441
    ISSN 0939-6411
    DOI 10.1016/j.ejpb.2021.08.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top