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  1. Article ; Online: Commentary on 'Implications of the SARS-CoV-2 subvariants BA.4 and BA.5'.

    Khani, Elnaz / Entezari-Maleki, Taher

    International journal of surgery (London, England)

    2023  Volume 109, Issue 1, Page(s) 75–76

    MeSH term(s) Humans ; SARS-CoV-2 ; COVID-19
    Language English
    Publishing date 2023-01-01
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 2212038-5
    ISSN 1743-9159 ; 1743-9191
    ISSN (online) 1743-9159
    ISSN 1743-9191
    DOI 10.1097/JS9.0000000000000095
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    Zs.A 6502: Show issues Location:
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  2. Article: New-onset systemic lupus erythematosus after BBIBP-CorV vaccination.

    Pourkarim, Fariba / Khani, Elnaz / Ghadakchi, Leila / Ebrahimian, Sanaz

    Clinical case reports

    2024  Volume 12, Issue 2, Page(s) e8547

    Abstract: While reports of new-onset systemic lupus erythematosus (SLE) after mRNA-based COVID-19 vaccines exist, no such reports have been documented following inactivated vaccines. We describe a case of SLE after receiving the BBIBP-CorV vaccine. The patient ... ...

    Abstract While reports of new-onset systemic lupus erythematosus (SLE) after mRNA-based COVID-19 vaccines exist, no such reports have been documented following inactivated vaccines. We describe a case of SLE after receiving the BBIBP-CorV vaccine. The patient exhibited characteristic SLE criteria, indicating a possible association between the inactivated vaccine and new-onset SLE.
    Language English
    Publishing date 2024-02-22
    Publishing country England
    Document type Case Reports
    ZDB-ID 2740234-4
    ISSN 2050-0904
    ISSN 2050-0904
    DOI 10.1002/ccr3.8547
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  3. Article ; Online: A commentary on "Unexpected sudden rise of human monkeypox cases in multiple non-endemic countries amid COVID-19 pandemic and salient counteracting strategies: Another potential global threat?" (Int J Surg 2022;103:106705).

    Khani, Elnaz / Entezari-Maleki, Taher

    International journal of surgery (London, England)

    2022  Volume 106, Page(s) 106868

    MeSH term(s) Humans ; COVID-19/epidemiology ; Pandemics/prevention & control ; Mpox (monkeypox)/epidemiology
    Language English
    Publishing date 2022-09-06
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2212038-5
    ISSN 1743-9159 ; 1743-9191
    ISSN (online) 1743-9159
    ISSN 1743-9191
    DOI 10.1016/j.ijsu.2022.106868
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  4. Article ; Online: Hypertensive Crisis Following COVID-19 Vaccination.

    Khani, Elnaz / Entezari-Maleki, Taher

    Journal of clinical pharmacology

    2022  Volume 62, Issue 8, Page(s) 1047–1048

    MeSH term(s) Angiotensin Receptor Antagonists ; Angiotensin-Converting Enzyme Inhibitors ; Antihypertensive Agents/therapeutic use ; COVID-19/prevention & control ; COVID-19 Vaccines/adverse effects ; Humans ; Hypertension/drug therapy ; Hypertension/etiology ; Vaccination
    Chemical Substances Angiotensin Receptor Antagonists ; Angiotensin-Converting Enzyme Inhibitors ; Antihypertensive Agents ; COVID-19 Vaccines
    Language English
    Publishing date 2022-02-27
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 188980-1
    ISSN 1552-4604 ; 0091-2700 ; 0021-9754
    ISSN (online) 1552-4604
    ISSN 0091-2700 ; 0021-9754
    DOI 10.1002/jcph.2037
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  5. Article ; Online: Fluvoxamine and long COVID-19; a new role for sigma-1 receptor (S1R) agonists.

    Khani, Elnaz / Entezari-Maleki, Taher

    Molecular psychiatry

    2022  Volume 27, Issue 9, Page(s) 3562

    MeSH term(s) Humans ; Fluvoxamine/therapeutic use ; COVID-19 ; Receptors, sigma/agonists ; COVID-19 Drug Treatment ; Post-Acute COVID-19 Syndrome ; Sigma-1 Receptor
    Chemical Substances Fluvoxamine (O4L1XPO44W) ; Receptors, sigma
    Language English
    Publishing date 2022-04-06
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 1330655-8
    ISSN 1476-5578 ; 1359-4184
    ISSN (online) 1476-5578
    ISSN 1359-4184
    DOI 10.1038/s41380-022-01545-3
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    Zs.A 4812: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Monkeypox treatment: Current evidence and future perspectives.

    Khani, Elnaz / Afsharirad, Bentelhoda / Entezari-Maleki, Taher

    Journal of medical virology

    2022  Volume 95, Issue 1, Page(s) e28229

    Abstract: As of September 11, 2022, 57 669 reports of monkeypox infection raised global concern. Previous vaccinia virus vaccination can protect from monkeypox. However, after smallpox eradication, immunization against that was stopped. Indeed, therapeutic options ...

    Abstract As of September 11, 2022, 57 669 reports of monkeypox infection raised global concern. Previous vaccinia virus vaccination can protect from monkeypox. However, after smallpox eradication, immunization against that was stopped. Indeed, therapeutic options following the disease onset are of great value. This study aimed to review the available evidence on virology and treatment approaches for monkeypox and provide guidance for patient care and future studies. Since no randomized clinical trials were ever performed, we reviewed monkeypox animal model studies and clinical trials on the safety and pharmacokinetics of available medications. Brincidofovir and tecovirimat were the most studied medications that got approval for smallpox treatment according to the Animal Rule. Due to the conserved virology among Orthopoxviruses, available medications might also be effective against monkeypox. However, tecovirimat has the strongest evidence to be effective and safe for monkeypox treatment, and if there is a choice between the two drugs, tecovirimat has shown more promise so far. The risk of resistance should be considered in patients who failed to respond to tecovirimat. Hence, the target-based design of novel antivirals will enhance the availability and spectrum of effective anti-Orthopoxvirus agents.
    MeSH term(s) Animals ; Mpox (monkeypox)/drug therapy ; Mpox (monkeypox)/prevention & control ; Smallpox/drug therapy ; Orthopoxvirus ; Vaccination ; Benzamides ; Isoindoles/therapeutic use
    Chemical Substances Benzamides ; Isoindoles
    Language English
    Publishing date 2022-11-07
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 752392-0
    ISSN 1096-9071 ; 0146-6615
    ISSN (online) 1096-9071
    ISSN 0146-6615
    DOI 10.1002/jmv.28229
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    Zs.A 1320: Show issues Location:
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    ab Jg. 2022: Lesesaal (EG)

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  7. Article: Effects of citalopram on blood pressure control in depressive patients with hypertension: A randomized clinical trial.

    Namdar, Hossein / Khani, Elnaz / Khiali, Sajad / Safaie, Naser / Ameli, Hedieh / Rahbari Banaeian, Gholamreza / Entezari-Maleki, Taher

    Journal of cardiovascular and thoracic research

    2024  Volume 16, Issue 1, Page(s) 49–54

    Abstract: Introduction: Since there is a bi-directional interaction between hypertension and depression, we aimed to evaluate the effects of citalopram administration in the management of hypertension.: Methods: A randomized clinical trial was conducted on 72 ... ...

    Abstract Introduction: Since there is a bi-directional interaction between hypertension and depression, we aimed to evaluate the effects of citalopram administration in the management of hypertension.
    Methods: A randomized clinical trial was conducted on 72 patients with concomitant depression and hypertension. The intervention group (n=41) received citalopram 20 mg daily plus anti-hypertensive standard treatment, while the control group (n=31) received only the standard treatment. The study's primary endpoint was in-office blood pressure (BP) measurement at baseline and home BP monitoring in the first and second months after entering the study.
    Results: There were no significant differences in baseline systolic BP (163.3±19.6 vs.164.2±20.3 mm Hg;
    Conclusion: This study supported the beneficial effects of citalopram in lowering BP in patients with concomitant depression and hypertension.
    Language English
    Publishing date 2024-03-13
    Publishing country Iran
    Document type Journal Article
    ZDB-ID 2654729-6
    ISSN 2008-6830 ; 2008-5117
    ISSN (online) 2008-6830
    ISSN 2008-5117
    DOI 10.34172/jcvtr.31849
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Investigational antiviral drugs for the treatment of COVID-19 patients.

    Beheshtirouy, Samineh / Khani, Elnaz / Khiali, Sajad / Entezari-Maleki, Taher

    Archives of virology

    2022  Volume 167, Issue 3, Page(s) 751–805

    Abstract: In the current pandemic of coronavirus disease 2019 (COVID-19), antiviral drugs are at the center of attention because of their critical role against severe acute respiratory disease syndrome coronavirus 2 (SARS-CoV-2). In addition to designing new ... ...

    Abstract In the current pandemic of coronavirus disease 2019 (COVID-19), antiviral drugs are at the center of attention because of their critical role against severe acute respiratory disease syndrome coronavirus 2 (SARS-CoV-2). In addition to designing new antivirals against SARS-COV-2, a drug repurposing strategy is a practical approach for treating COVID-19. A brief insight about antivirals would help clinicians to choose the best medication for the treatment of COVID-19. In this review, we discuss both novel and repurposed investigational antivirals, focusing on in vitro, in vivo, and clinical trial studies.
    MeSH term(s) Antiviral Agents/therapeutic use ; COVID-19/drug therapy ; Drug Repositioning ; Drugs, Investigational/therapeutic use ; Humans ; Pandemics ; SARS-CoV-2
    Chemical Substances Antiviral Agents ; Drugs, Investigational
    Language English
    Publishing date 2022-02-09
    Publishing country Austria
    Document type Journal Article ; Review
    ZDB-ID 7491-3
    ISSN 1432-8798 ; 0304-8608
    ISSN (online) 1432-8798
    ISSN 0304-8608
    DOI 10.1007/s00705-022-05368-z
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    Ud II Zs.110: Show issues Location:
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  9. Article ; Online: Comprehensive review on molnupiravir in COVID-19: a novel promising antiviral to combat the pandemic.

    Khiali, Sajad / Khani, Elnaz / B Rouy, Samineh / Entezari-Maleki, Taher

    Future microbiology

    2022  Volume 17, Page(s) 377–391

    Abstract: Despite the progress in the management of COVID-19, effective oral antiviral agents are still lacking. In the present review, the potential beneficial effects of molnupiravir in the management of COVID-19 are discussed. A literature search in Google ... ...

    Abstract Despite the progress in the management of COVID-19, effective oral antiviral agents are still lacking. In the present review, the potential beneficial effects of molnupiravir in the management of COVID-19 are discussed. A literature search in Google Scholar, Scopus, PubMed and clinicaltrials.gov for the relevant articles regarding the pharmacokinetics, pharmacodynamics and clinical trials of molnupiravir in the management of COVID-19 is conducted. Most of the preclinical studies and available clinical trials showed a favorable short-term safety profile of molnupiravir; however, given its possible genotoxic effects, further trials are required to confirm the long-term efficacy and safety of molnupiravir in patients with COVID-19.
    MeSH term(s) Antiviral Agents/pharmacology ; Antiviral Agents/therapeutic use ; COVID-19/drug therapy ; Cytidine/analogs & derivatives ; Humans ; Hydroxylamines ; Pandemics ; SARS-CoV-2
    Chemical Substances Antiviral Agents ; Hydroxylamines ; Cytidine (5CSZ8459RP) ; molnupiravir (YA84KI1VEW)
    Language English
    Publishing date 2022-02-24
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2254620-0
    ISSN 1746-0921 ; 1746-0913
    ISSN (online) 1746-0921
    ISSN 1746-0913
    DOI 10.2217/fmb-2021-0252
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Effects of Triamterene in Hospitalized Patients with Heart Failure and Diuretic Resistance: A Randomized Clinical Trial.

    Taban-Sadeghi, Mohammadreza / Khani, Elnaz / Khezripour, Kimia / Enamzadeh, Elgar / Safaei, Naser / Entezari-Maleki, Taher

    Journal of clinical pharmacology

    2023  Volume 63, Issue 12, Page(s) 1352–1358

    Abstract: Due to the potential benefits of triamterene in diuretic resistance, this study was performed to assess whether triamterene add-on to the standard treatment of heart failure (HF)-related diuretic resistance improves outcomes. A randomized clinical trial ... ...

    Abstract Due to the potential benefits of triamterene in diuretic resistance, this study was performed to assess whether triamterene add-on to the standard treatment of heart failure (HF)-related diuretic resistance improves outcomes. A randomized clinical trial was performed on 45 hospitalized patients with HF with reduced ejection fraction who had diuretic resistance. Patients were randomized to receive either triamterene 50 mg plus hydrochlorothiazide 25 mg (n = 23) or hydrochlorothiazide 50 mg alone (n = 22) until hospital discharge. The primary outcomes were changes in weight and fluid input-to-output ratio. Secondary outcomes were respiratory rate, hospitalization duration, serum sodium and potassium, estimated glomerular filtration rate, creatinine, and blood urea nitrogen levels during the study period. The mean (standard deviation) of weight changes was not significantly different in the intervention and the control groups (-6.3 [4.8] vs -4.8 [2.4] kg, respectively; P = .1). No significant differences were shown in input-to-output changes between the 2 groups (208.0 [243.4] in the intervention and 600.2 [250.3] in the control group; P = .4). Although the respiratory rate of triamterene-treated patients decreased, the difference did not reach statistical significance (P = .2). Other secondary outcomes were also similar in both groups. This study did not support the use of triamterene as an add-on therapy for patients with HF-related diuretic resistance.
    MeSH term(s) Humans ; Diuretics/therapeutic use ; Triamterene/therapeutic use ; Heart Failure/drug therapy ; Hydrochlorothiazide/therapeutic use ; Potassium/therapeutic use
    Chemical Substances Diuretics ; Triamterene (WS821Z52LQ) ; Hydrochlorothiazide (0J48LPH2TH) ; Potassium (RWP5GA015D)
    Language English
    Publishing date 2023-08-10
    Publishing country England
    Document type Randomized Controlled Trial ; Journal Article
    ZDB-ID 188980-1
    ISSN 1552-4604 ; 0091-2700 ; 0021-9754
    ISSN (online) 1552-4604
    ISSN 0091-2700 ; 0021-9754
    DOI 10.1002/jcph.2321
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