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  1. Article ; Online: Potential Interactions of Remdesivir with Pulmonary Drugs: a Covid-19 Perspective.

    Gandhi, Zainab / Mansuri, Zeeshan / Bansod, Snehal

    SN comprehensive clinical medicine

    2020  Volume 2, Issue 10, Page(s) 1707–1708

    Abstract: In this letter, we discuss the potential interactions of remdesivir, the newly approved Covid-19 drug with pulmonary medications. These interactions have been summarized keeping the busy clinician in mind. While remdesivir has proven to be a safe ... ...

    Abstract In this letter, we discuss the potential interactions of remdesivir, the newly approved Covid-19 drug with pulmonary medications. These interactions have been summarized keeping the busy clinician in mind. While remdesivir has proven to be a safe medication generally, we here have enlisted the potential interactions of remdesivir that a clinician needs to be mindful of while prescribing the medication.
    Keywords covid19
    Language English
    Publishing date 2020-08-21
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2947211-8
    ISSN 2523-8973 ; 2523-8973
    ISSN (online) 2523-8973
    ISSN 2523-8973
    DOI 10.1007/s42399-020-00462-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Nationwide Trends in Hospitalizations and Outcomes of Pulmonary Circulation Disorders Among Patients With Cannabis Use Disorder in the United States.

    Jain, Akhil / Gandhi, Zainab / Desai, Rupak / Mansuri, Uvesh / Rizvi, Bisharah / Alvarez, Melissa / Gupta, Puneet

    Cureus

    2022  Volume 14, Issue 3, Page(s) e22897

    Abstract: Background and objective The use of cannabis through smoking and vaping has increased significantly over the past decade. However, the prevalence of pulmonary circulation disorder (PCD)-related hospitalizations among cannabis users and their outcomes ... ...

    Abstract Background and objective The use of cannabis through smoking and vaping has increased significantly over the past decade. However, the prevalence of pulmonary circulation disorder (PCD)-related hospitalizations among cannabis users and their outcomes remain poorly understood. In this study, we used a nationally representative sample to assess the prevalence and trends of hospitalization among cannabis users with PCD. Methods The National Inpatient Sample (NIS) datasets (2007-2014) were used to analyze hospitalizations of patients with cannabis user disorder with PCD (C-PCD arm) versus those without PCD (C-non-PCD arm) to ascertain demographics, comorbidities, and in-hospital outcomes including all-cause mortality and healthcare resource utilization. Results A total of 3,307,310 hospitalizations involving cannabis users were reported, of which 20,328 (0.61%) were related to PCD. We noted a 200% relative increase in hospitalizations in the C-PCD arm (linearly increasing from 0.3% to 0.9% from 2007 to 2014, p
    Language English
    Publishing date 2022-03-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.22897
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Nationwide trends in stroke hospitalizations among patients with prediabetes.

    Fong, Hee Kong / Gandhi, Zainab / Lodhi, Muhammad Uzair / Savani, Sejal / Desai, Virmitra / Desai, Rupak

    International journal of cardiology. Heart & vasculature

    2020  Volume 30, Page(s) 100622

    Language English
    Publishing date 2020-08-29
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 2818464-6
    ISSN 2352-9067
    ISSN 2352-9067
    DOI 10.1016/j.ijcha.2020.100622
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Outcomes of cardiac arrest hospitalizations in patients with obesity with versus without prior bariatric surgery status:A nationwide propensity-matched analysis.

    Desai, Rupak / Gandhi, Zainab / Ravalani, Abhimanyu / Mahfooz, Kamran / Mansuri, Uvesh / Jain, Akhil / Vyas, Ankit / Gupta, Rajeev / Lavie, Carl J

    International journal of cardiology. Cardiovascular risk and prevention

    2023  Volume 20, Page(s) 200235

    Abstract: Introduction: Prior bariatric surgery (PBS) status in obese patients is thought to curtail the risk of cardiovascular events, but its role in change of outcomes of patients with obesity developing new acute cardiac events such as cardiac arrests (CA) ... ...

    Abstract Introduction: Prior bariatric surgery (PBS) status in obese patients is thought to curtail the risk of cardiovascular events, but its role in change of outcomes of patients with obesity developing new acute cardiac events such as cardiac arrests (CA) remains largely unknown.
    Methods: Hospitalizations among adult patients with obesity and CA were identified retrospectively using the National Inpatient Sample (2015 October-2017 December). Propensity-matched analysis (1:1) was performed for sociodemographic/hospital characteristics to identify two cohorts, with (PBS+) or without (PBS-) status. The primary endpoint was in-hospital mortality, and the secondary endpoint was healthcare resource utilization.
    Results: Both cohorts (n = 1275 each), had patients with comparable age (mean 58 years), with a higher frequency of white (>70 %), females (>60 %), and Medicare enrollees (>40 %). PBS + cohort had lower rates of diabetes (27.8 % vs 36.1 %), hyperlipidemia (33.7 % vs 48.6 %), renal failure (17.3 % vs 22.0 %), chronic pulmonary disease (11.8 % vs 21.2 %) and higher rates of anemias (18.4 % vs 12.2 %), liver disease (5.1 % vs 2.4 %) and alcohol abuse (6.7 % vs 2.4 %) than PBS- cohort (p < 0.05). All-cause mortality (46.3 % vs 45.1 %, p = 0.551) was comparable between the two cohorts. The PBS + cohort was less often transferred routinely (p<0.001) but had a shorter hospital stay (p<0.001) with equivalent hospital charges compared to the PBS- cohort.
    Conclusions: The PBS status (regardless of chronology) did not increase survival in CA admissions among patients with obesity. Preventive measures are necessary to manage enduring cardiovascular disease risk factors that may limit the advantages of surgery for patients with obesity and aggravate the worse outcomes of future cardiac events.
    Language English
    Publishing date 2023-12-22
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2772-4875
    ISSN (online) 2772-4875
    DOI 10.1016/j.ijcrp.2023.200235
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Ambulatory blood pressure levels in individuals with uncontrolled clinic hypertension across Bangladesh, Pakistan, and Sri Lanka.

    Zhu, Anqi / Ostbye, Truls / Naheed, Aliya / de Silva, H Asita / Jehan, Imtiaz / Gandhi, Mihir / Chakma, Nantu / Kasturiratne, Anuradhani / Samad, Zainab / Jafar, Tazeen Hasan

    Journal of clinical hypertension (Greenwich, Conn.)

    2024  Volume 26, Issue 4, Page(s) 391–404

    Abstract: Hypertension is a leading risk factor for cardiovascular disease in South Asia. The authors aimed to assess the cross-country differences in 24-h ambulatory, daytime, and nighttime systolic blood pressure (SBP) among rural population with uncontrolled ... ...

    Abstract Hypertension is a leading risk factor for cardiovascular disease in South Asia. The authors aimed to assess the cross-country differences in 24-h ambulatory, daytime, and nighttime systolic blood pressure (SBP) among rural population with uncontrolled clinic hypertension in Bangladesh, Pakistan, and Sri Lanka. The authors studied patients with uncontrolled clinic hypertension (clinic BP ≥ 140/90 mmHg) who underwent ambulatory blood pressure monitoring (ABPM) during the baseline assessment as part of a community-based trial. The authors compared the distribution of ABPM profiles of patients across the three countries, specifically evaluating ambulatory SBP levels with multivariable models that adjusted for patient characteristics. Among the 382 patients (mean age, 58.3 years; 64.7% women), 56.5% exhibited ambulatory hypertension (24-h ambulatory BP ≥ 130/80 mmHg), with wide variation across countries: 72.6% (Bangladesh), 50.0% (Pakistan), and 51.0% (Sri Lanka; P < .05). Compared to Sri Lanka, adjusted mean 24-h ambulatory, daytime, and nighttime SBP were higher by 12.24 mmHg (95% CI 4.28-20.20), 11.96 mmHg (3.87-20.06), and 12.76 mmHg (4.51-21.01) in Bangladesh, separately. However, no significant differences were observed between Pakistan and Sri Lanka (P > .05). Additionally, clinic SBP was significantly associated with 24-h ambulatory (mean 0.38, 95% CI 0.28-0.47), daytime (0.37, 0.27-0.47), and nighttime SBP (0.40, 0.29-0.50) per 1 mmHg increase. The authors observed substantial cross-country differences in the distribution of ABPM profiles among patients with uncontrolled clinic hypertension in rural South Asia. The authors findings indicated the need to incorporate 24-h BP monitoring to mitigate cardiovascular risk, particularly in Bangladesh.
    MeSH term(s) Female ; Humans ; Male ; Middle Aged ; Bangladesh/epidemiology ; Blood Pressure ; Blood Pressure Monitoring, Ambulatory ; Hypertension/epidemiology ; Pakistan/epidemiology ; Sri Lanka/epidemiology
    Language English
    Publishing date 2024-03-07
    Publishing country United States
    Document type Comparative Study ; Journal Article
    ZDB-ID 2077222-1
    ISSN 1751-7176 ; 1524-6175
    ISSN (online) 1751-7176
    ISSN 1524-6175
    DOI 10.1111/jch.14787
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Potential Interactions of Remdesivir with Pulmonary Drugs

    Gandhi, Zainab / Mansuri, Zeeshan / Bansod, Snehal

    SN Comprehensive Clinical Medicine ; ISSN 2523-8973

    a Covid-19 Perspective

    2020  

    Keywords covid19
    Language English
    Publisher Springer Science and Business Media LLC
    Publishing country us
    Document type Article ; Online
    DOI 10.1007/s42399-020-00462-2
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article: Recurrent/Subsequent Stroke and Associated Outcomes in Geriatric Patients with OSA and Prior Stroke Events: A Retrospective Study Using the 2019 National Inpatient Sample.

    Desai, Rupak / Singh, Sandeep / Mellacheruvu, Sai Priyanka / Mohammed, Adil Sarvar / Soni, Roshni / Perera, Ayodya / Makarla, Venkata Akhil / Santhosh, Sarayu / Siddiqui, Muneeb Ali / Mohammed, Bilal Khan / Mohammed, Zaki Ur Rahman / Gandhi, Zainab / Vyas, Ankit / Jain, Akhil / Sachdeva, Rajesh / Kumar, Gautam

    Journal of personalized medicine

    2023  Volume 13, Issue 5

    Abstract: ... ...

    Abstract Background
    Language English
    Publishing date 2023-04-30
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662248-8
    ISSN 2075-4426
    ISSN 2075-4426
    DOI 10.3390/jpm13050782
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Potential Interactions of Remdesivir with Pulmonary Drugs: a Covid-19 Perspective

    Gandhi, Zainab / Mansuri, Zeeshan / Bansod, Snehal

    SN Compr Clin Med

    Abstract: In this letter, we discuss the potential interactions of remdesivir, the newly approved Covid-19 drug with pulmonary medications. These interactions have been summarized keeping the busy clinician in mind. While remdesivir has proven to be a safe ... ...

    Abstract In this letter, we discuss the potential interactions of remdesivir, the newly approved Covid-19 drug with pulmonary medications. These interactions have been summarized keeping the busy clinician in mind. While remdesivir has proven to be a safe medication generally, we here have enlisted the potential interactions of remdesivir that a clinician needs to be mindful of while prescribing the medication.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #724017
    Database COVID19

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  9. Article ; Online: The influence of wearing a mask on the projected first impressions and attractiveness levels of smiling individuals.

    Dayan, Steven / Fabi, Sabrina / Gandhi, Nimit / Scharf, Isabel / Resner, Alexea / Lian, Lien / Kola, Eljona / Jabri, Zainab

    Journal of cosmetic dermatology

    2022  

    Abstract: Objective: To evaluate the effect of mask wearing on facial attractiveness and projected first impressions during the COVID-19 pandemic.: Methods: A total of eight models were evaluated by 200 live raters and 750 online raters both with and without ... ...

    Abstract Objective: To evaluate the effect of mask wearing on facial attractiveness and projected first impressions during the COVID-19 pandemic.
    Methods: A total of eight models were evaluated by 200 live raters and 750 online raters both with and without masks while smiling maximally. Both live and online raters looked at the models for 15 s, then completed a first impressions questionnaire.
    Results: Overall ratings for attractiveness were higher for both masked and unmasked conditions in-person versus online. Males were perceived more favorably both in impressions and attractiveness online when masked, whereas in person they were more favorable when unmasked. Females were perceived more favorably in impressions when unmasked both online and in person, but their attractiveness rating was higher when masked both online and in person. Regardless of gender and masking state, all first impressions were more favorable in person versus online. The differences were statistically significant (all p < 0.05).
    Conclusions: Face masks have different effects for males versus females in both an online and in-person setting. Men are perceived more positively in-person when they smile unmasked while they are better ranked online when they smile masked. Females are better perceived in all domains other than attractiveness when smiling unmasked both online and in person. To optimize first impressions, individuals should seek to meet in person whenever possible when forming new relationships.
    Language English
    Publishing date 2022-09-27
    Publishing country England
    Document type Journal Article
    ZDB-ID 2280551-5
    ISSN 1473-2165 ; 1473-2130
    ISSN (online) 1473-2165
    ISSN 1473-2130
    DOI 10.1111/jocd.15395
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Artificial Intelligence and Lung Cancer: Impact on Improving Patient Outcomes.

    Gandhi, Zainab / Gurram, Priyatham / Amgai, Birendra / Lekkala, Sai Prasanna / Lokhandwala, Alifya / Manne, Suvidha / Mohammed, Adil / Koshiya, Hiren / Dewaswala, Nakeya / Desai, Rupak / Bhopalwala, Huzaifa / Ganti, Shyam / Surani, Salim

    Cancers

    2023  Volume 15, Issue 21

    Abstract: Lung cancer remains one of the leading causes of cancer-related deaths worldwide, emphasizing the need for improved diagnostic and treatment approaches. In recent years, the emergence of artificial intelligence (AI) has sparked considerable interest in ... ...

    Abstract Lung cancer remains one of the leading causes of cancer-related deaths worldwide, emphasizing the need for improved diagnostic and treatment approaches. In recent years, the emergence of artificial intelligence (AI) has sparked considerable interest in its potential role in lung cancer. This review aims to provide an overview of the current state of AI applications in lung cancer screening, diagnosis, and treatment. AI algorithms like machine learning, deep learning, and radiomics have shown remarkable capabilities in the detection and characterization of lung nodules, thereby aiding in accurate lung cancer screening and diagnosis. These systems can analyze various imaging modalities, such as low-dose CT scans, PET-CT imaging, and even chest radiographs, accurately identifying suspicious nodules and facilitating timely intervention. AI models have exhibited promise in utilizing biomarkers and tumor markers as supplementary screening tools, effectively enhancing the specificity and accuracy of early detection. These models can accurately distinguish between benign and malignant lung nodules, assisting radiologists in making more accurate and informed diagnostic decisions. Additionally, AI algorithms hold the potential to integrate multiple imaging modalities and clinical data, providing a more comprehensive diagnostic assessment. By utilizing high-quality data, including patient demographics, clinical history, and genetic profiles, AI models can predict treatment responses and guide the selection of optimal therapies. Notably, these models have shown considerable success in predicting the likelihood of response and recurrence following targeted therapies and optimizing radiation therapy for lung cancer patients. Implementing these AI tools in clinical practice can aid in the early diagnosis and timely management of lung cancer and potentially improve outcomes, including the mortality and morbidity of the patients.
    Language English
    Publishing date 2023-10-31
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers15215236
    Database MEDical Literature Analysis and Retrieval System OnLINE

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