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  1. Article ; Online: The emerging role of lipidomics in prediction of diseases.

    Han, Xianlin

    Nature reviews. Endocrinology

    2022  Volume 18, Issue 6, Page(s) 335–336

    MeSH term(s) Biomarkers ; Humans ; Lipid Metabolism ; Lipidomics
    Chemical Substances Biomarkers
    Language English
    Publishing date 2022-04-07
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Comment
    ZDB-ID 2489381-X
    ISSN 1759-5037 ; 1759-5029
    ISSN (online) 1759-5037
    ISSN 1759-5029
    DOI 10.1038/s41574-022-00672-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Myelin lipid deficiency: a new key driver of Alzheimer's disease.

    Qiu, Shulan / Palavicini, Juan Pablo / Han, Xianlin

    Neural regeneration research

    2022  Volume 18, Issue 1, Page(s) 121–122

    Language English
    Publishing date 2022-07-01
    Publishing country India
    Document type Journal Article
    ZDB-ID 2388460-5
    ISSN 1876-7958 ; 1673-5374
    ISSN (online) 1876-7958
    ISSN 1673-5374
    DOI 10.4103/
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  3. Article ; Online: Correction: Sphingomyelin synthase-related protein SMSr is a phosphatidylethanolamine phospholipase C that promotes nonalcoholic fatty liver disease.

    Chiang, Yeun-Po / Li, Zhiqiang / He, Mulin / Jones, Quiana / Pan, Meixia / Han, Xianlin / Jiang, Xian-Cheng

    The Journal of biological chemistry

    2024  Volume 300, Issue 4, Page(s) 107204

    Language English
    Publishing date 2024-03-28
    Publishing country United States
    Document type Published Erratum
    ZDB-ID 2997-x
    ISSN 1083-351X ; 0021-9258
    ISSN (online) 1083-351X
    ISSN 0021-9258
    DOI 10.1016/j.jbc.2024.107204
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Lipidomics for precision medicine and metabolism: A personal view.

    Han, Xianlin

    Biochimica et biophysica acta. Molecular and cell biology of lipids

    2017  Volume 1862, Issue 8, Page(s) 804–807

    MeSH term(s) Animals ; Humans ; Lipid Metabolism/physiology ; Lipids/chemistry ; Precision Medicine/methods
    Chemical Substances Lipids
    Language English
    Publishing date 2017-02-24
    Publishing country Netherlands
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, N.I.H., Intramural ; Review
    ZDB-ID 60-7
    ISSN 1879-2596 ; 1879-260X ; 1872-8006 ; 1879-2642 ; 1879-2618 ; 1879-2650 ; 1879-2618 ; 0006-3002 ; 0005-2728 ; 0005-2736 ; 0304-4165 ; 0167-4838 ; 1388-1981 ; 0167-4889 ; 0167-4781 ; 0304-419X ; 1570-9639 ; 0925-4439 ; 1874-9399
    ISSN (online) 1879-2596 ; 1879-260X ; 1872-8006 ; 1879-2642 ; 1879-2618 ; 1879-2650
    ISSN 1879-2618 ; 0006-3002 ; 0005-2728 ; 0005-2736 ; 0304-4165 ; 0167-4838 ; 1388-1981 ; 0167-4889 ; 0167-4781 ; 0304-419X ; 1570-9639 ; 0925-4439 ; 1874-9399
    DOI 10.1016/j.bbalip.2017.02.012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Neostigmine for non-mild acute pancreatitis: A systematic review and meta-analysis of randomized controlled trials.

    He, Kun / Wang, Yabing / Li, Jianing / Bai, Xiaoyin / Yang, Zihan / Han, Xianlin / Wu, Dong

    Frontiers in pharmacology

    2023  Volume 14, Page(s) 1131974

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2023-02-28
    Publishing country Switzerland
    Document type Systematic Review
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2023.1131974
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  6. Article: Pancreatic carcinoma disguised as type 1 autoimmune pancreatitis with a mass-forming appearance: a clinical dilemma.

    Yan, Zhiyu / Chang, Xiaoyan / Bai, Xiaoyin / Han, Xianlin / Feng, Yunlu / Yang, Aiming

    Hepatobiliary surgery and nutrition

    2023  Volume 12, Issue 6, Page(s) 997–1000

    Language English
    Publishing date 2023-11-15
    Publishing country China (Republic : 1949- )
    Document type Case Reports
    ZDB-ID 2812398-0
    ISSN 2304-389X ; 2304-3881
    ISSN (online) 2304-389X
    ISSN 2304-3881
    DOI 10.21037/hbsn-23-436
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Laparoscopic radical distal pancreatectomy with portal venous tumor thrombectomy for the treatment of pancreatic acinar cell carcinoma after neoadjuvant chemotherapy.

    Sun, Mengqing / Bai, Xuesong / Chang, Xiaoyan / Wu, Huanwen / Cheng, Yuejuan / He, Xiaodong / Han, Xianlin

    Hepatobiliary surgery and nutrition

    2023  Volume 12, Issue 6, Page(s) 991–996

    Language English
    Publishing date 2023-11-15
    Publishing country China (Republic : 1949- )
    Document type Journal Article ; Comment
    ZDB-ID 2812398-0
    ISSN 2304-389X ; 2304-3881
    ISSN (online) 2304-389X
    ISSN 2304-3881
    DOI 10.21037/hbsn-23-395
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  8. Article: EUS in the diagnosis of peripancreatic Castleman disease: A case report (with video).

    Han, Ziying / Han, Xianlin / Li, Yuan / Feng, Yunlu / Zhang, Shengyu / Yang, Aiming

    Endoscopic ultrasound

    2022  Volume 12, Issue 2, Page(s) 281–283

    Language English
    Publishing date 2022-12-09
    Publishing country China
    Document type Journal Article
    ZDB-ID 2998317-4
    ISSN 2226-7190 ; 2303-9027
    ISSN (online) 2226-7190
    ISSN 2303-9027
    DOI 10.4103/EUS-D-22-00057
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Inspired by game theory: Multi-signal output photoelectrochemical point-of-care immunoassay based on target-triggered organic electronic barriers.

    Han, Xianlin / Lin, Shujin / Cheng, Cui / Han, Xiao / Tang, Dianping

    Analytica chimica acta

    2023  Volume 1265, Page(s) 341362

    Abstract: This work presents an integrated photoelectrochemical, impedance and colorimetric biosensing platform for flexible detection of cancer markers based on the targeted response by combining liposome amplification strategies and target-induced non-in situ ... ...

    Abstract This work presents an integrated photoelectrochemical, impedance and colorimetric biosensing platform for flexible detection of cancer markers based on the targeted response by combining liposome amplification strategies and target-induced non-in situ formation of electronic barriers as the signal transduction modality on carbon-modified CdS photoanodes. Inspired by game theory, the carbon layer modified CdS hyperbranched structure with low impedance and high photocurrent response was firstly obtained by surface modification of CdS nanomaterials. Through a liposome-mediated enzymatic reaction amplification strategy, a large number of organic electron barriers were formed by a biocatalytic precipitation (BCP) reaction triggered by horseradish peroxidase released from cleaved liposomes after the introduction of the target molecule, thereby increasing the impedance characteristics of the photoanode as well as attenuating the photocurrent. The BCP reaction in the microplate was accompanied by a significant color change, which opened up a new window for point-of-care testing. Taking carcinoembryonic antigen (CEA) as a proof of concept, the multi-signal output sensing platform showed a satisfactory sensitive response to CEA with an optimal linear range of 20 pg mL
    MeSH term(s) Humans ; Carcinoembryonic Antigen ; Point-of-Care Systems ; Liposomes ; Biosensing Techniques/methods ; Electrochemical Techniques/methods ; Carbon ; Immunoassay/methods ; Neoplasms ; Limit of Detection
    Chemical Substances Carcinoembryonic Antigen ; Liposomes ; Carbon (7440-44-0)
    Language English
    Publishing date 2023-05-12
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1483436-4
    ISSN 1873-4324 ; 0003-2670
    ISSN (online) 1873-4324
    ISSN 0003-2670
    DOI 10.1016/j.aca.2023.341362
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: The foundations and development of lipidomics.

    Han, Xianlin / Gross, Richard W

    Journal of lipid research

    2021  Volume 63, Issue 2, Page(s) 100164

    Abstract: For over a century, the importance of lipid metabolism in biology was recognized but difficult to mechanistically understand due to the lack of sensitive and robust technologies for identification and quantification of lipid molecular species. The ... ...

    Abstract For over a century, the importance of lipid metabolism in biology was recognized but difficult to mechanistically understand due to the lack of sensitive and robust technologies for identification and quantification of lipid molecular species. The enabling technological breakthroughs emerged in the 1980s with the development of soft ionization methods (Electrospray Ionization and Matrix Assisted Laser Desorption/Ionization) that could identify and quantify intact individual lipid molecular species. These soft ionization technologies laid the foundations for what was to be later named the field of lipidomics. Further innovative advances in multistage fragmentation, dramatic improvements in resolution and mass accuracy, and multiplexed sample analysis fueled the early growth of lipidomics through the early 1990s. The field exponentially grew through the use of a variety of strategic approaches, which included direct infusion, chromatographic separation, and charge-switch derivatization, which facilitated access to the low abundance species of the lipidome. In this Thematic Review, we provide a broad perspective of the foundations, enabling advances, and predicted future directions of growth of the lipidomics field.
    MeSH term(s) Lipidomics
    Language English
    Publishing date 2021-12-22
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 80154-9
    ISSN 1539-7262 ; 0022-2275
    ISSN (online) 1539-7262
    ISSN 0022-2275
    DOI 10.1016/j.jlr.2021.100164
    Database MEDical Literature Analysis and Retrieval System OnLINE

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