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  1. Book: Immunohistochemistry and immunocytochemistry

    Valle, Luis del

    methods and protocols

    (Methods in molecular biology ; 2422 ; Springer protocols)

    2022  

    Author's details edited by Luis Del Valle
    Series title Methods in molecular biology ; 2422
    Springer protocols
    Collection
    Keywords Immunohistochemistry ; Immunocytochemistry
    Subject code 616.0756
    Language English
    Size x, 286 Seiten, Illustrationen, Diagramme, 26 cm
    Publisher Humana Press
    Publishing place New York, NY
    Publishing country United States
    Document type Book
    HBZ-ID HT021181083
    ISBN 978-1-0716-1947-6 ; 9781071619483 ; 1-0716-1947-0 ; 1071619489
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Zs A 7042 -2422- not available for loan Lesesaal EG

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  2. Article: Identification and Clinical Characteristics of Community-Acquired

    Silva-Caso, Wilmer / Pérez-Lazo, Giancarlo / Aguilar-Luis, Miguel Angel / Morales-Moreno, Adriana / Ballena-López, José / Soto-Febres, Fernando / Martins-Luna, Johanna / Del Valle, Luis J / Kym, Sungmin / Aguilar-Luis, Deysi / Denegri-Hinostroza, Dayana / Del Valle-Mendoza, Juana

    Antibiotics (Basel, Switzerland)

    2024  Volume 13, Issue 3

    Abstract: Acinetobacter ... ...

    Abstract Acinetobacter baumannii
    Language English
    Publishing date 2024-03-16
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2681345-2
    ISSN 2079-6382
    ISSN 2079-6382
    DOI 10.3390/antibiotics13030266
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Parasitosis by

    Silva-Caso, Wilmer / Carrillo-Ng, Hugo / Aguilar-Luis, Miguel Angel / Tarazona-Castro, Yordi / Valle, Luis J Del / Tinco-Valdez, Carmen / Palomares-Reyes, Carlos / Urteaga, Numan / Bazán-Mayra, Jorge / Valle-Mendoza, Juana Del

    Microorganisms

    2024  Volume 12, Issue 2

    Abstract: ... in the Peruvian Andean valleys. Our objective was to determine variations in the composition of the gut microbiota ...

    Abstract (1) Background: Human fascioliasis is considered an endemic and hyper-endemic disease in the Peruvian Andean valleys. Our objective was to determine variations in the composition of the gut microbiota among children with
    Language English
    Publishing date 2024-02-11
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2720891-6
    ISSN 2076-2607
    ISSN 2076-2607
    DOI 10.3390/microorganisms12020371
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Copolymers and Blends Based on 3-Hydroxybutyrate and 3-Hydroxyvalerate Units.

    Jin, Anyi / Del Valle, Luis J / Puiggalí, Jordi

    International journal of molecular sciences

    2023  Volume 24, Issue 24

    Abstract: This review presents a comprehensive update of the biopolymer poly(3-hydroxybutyrate- ...

    Abstract This review presents a comprehensive update of the biopolymer poly(3-hydroxybutyrate-
    MeSH term(s) 3-Hydroxybutyric Acid ; Polyesters/chemistry ; Polymers ; Pentanoic Acids
    Chemical Substances 3-Hydroxybutyric Acid (TZP1275679) ; Polyesters ; beta-hydroxyvaleric acid (10237-77-1) ; Polymers ; Pentanoic Acids
    Language English
    Publishing date 2023-12-08
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms242417250
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Editorial: Epigenetics and molecular genetics of rare tumors.

    Tognon, Mauro / Calin, George A / Del Valle, Luis

    Frontiers in oncology

    2022  Volume 12, Page(s) 1049140

    Language English
    Publishing date 2022-11-03
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2649216-7
    ISSN 2234-943X
    ISSN 2234-943X
    DOI 10.3389/fonc.2022.1049140
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Introduction to Immunohistochemistry: From to Evolving Science to Timeless Art.

    Del Valle, Luis

    Methods in molecular biology (Clifton, N.J.)

    2021  Volume 2422, Page(s) 1–16

    Abstract: Immunohistochemistry and all techniques that use antibodies and fluorescence are widespread, essential and irreplaceable tools used in both research laboratory settings and diagnostic pathology laboratories. The field was born approximately 80 years ago, ...

    Abstract Immunohistochemistry and all techniques that use antibodies and fluorescence are widespread, essential and irreplaceable tools used in both research laboratory settings and diagnostic pathology laboratories. The field was born approximately 80 years ago, with the idea that antibodies could be tagged with fluorescent substances and used to detect antigens in cells and microorganisms, and has vertiginously evolved since; these advances have come in all aspects of the methodology, tissue fixation, generation of antibodies, monoclonal antibodies, signal amplification, antigen retrieval, signal amplification, microscopy and have become increasingly sophisticated, from in situ hybridization, in situ proximity ligation assay, flow cytometry, comet assay, to multiplexing and green fluorescent protein reconstitution, yielding Nobel Prizes along the way and generating invaluable scientific and diagnostic advances as well as timeless beautiful images.
    MeSH term(s) Antibodies, Monoclonal ; Antigens ; Biotin ; Immunohistochemistry ; Tyramine
    Chemical Substances Antibodies, Monoclonal ; Antigens ; Biotin (6SO6U10H04) ; Tyramine (X8ZC7V0OX3)
    Language English
    Publishing date 2021-12-02
    Publishing country United States
    Document type Journal Article
    ISSN 1940-6029
    ISSN (online) 1940-6029
    DOI 10.1007/978-1-0716-1948-3_1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Co-Detection of EBV and Human Polyomavirus JCPyV in a Case of AIDS-Related Multifocal Primary Central Nervous System Diffuse Large B-Cell Lymphoma.

    Barbier, Mallory T / Del Valle, Luis

    Viruses

    2023  Volume 15, Issue 3

    Abstract: The human ... ...

    Abstract The human neurotropic
    MeSH term(s) Humans ; Polyomavirus/genetics ; Herpesvirus 4, Human/genetics ; Herpesvirus 4, Human/metabolism ; JC Virus/physiology ; Acquired Immunodeficiency Syndrome ; Viral Proteins/genetics ; Antigens, Viral, Tumor/genetics ; Brain Neoplasms ; Lymphoma, Large B-Cell, Diffuse ; Central Nervous System/metabolism
    Chemical Substances Viral Proteins ; Antigens, Viral, Tumor
    Language English
    Publishing date 2023-03-15
    Publishing country Switzerland
    Document type Case Reports ; Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 2516098-9
    ISSN 1999-4915 ; 1999-4915
    ISSN (online) 1999-4915
    ISSN 1999-4915
    DOI 10.3390/v15030755
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Induction of Brain Tumors by the Archetype Strain of Human Neurotropic JCPyV in a Transgenic Mouse Model.

    Del Valle, Luis / Khalili, Kamel

    Viruses

    2021  Volume 13, Issue 2

    Abstract: JC Virus (JCPyV), a member of ... ...

    Abstract JC Virus (JCPyV), a member of the
    MeSH term(s) Animals ; Antigens, Viral, Tumor/genetics ; Antigens, Viral, Tumor/physiology ; Brain/metabolism ; Brain Neoplasms/pathology ; Brain Neoplasms/virology ; Capsid Proteins/genetics ; Disease Models, Animal ; Humans ; JC Virus/genetics ; JC Virus/pathogenicity ; Leukoencephalopathy, Progressive Multifocal/pathology ; Leukoencephalopathy, Progressive Multifocal/virology ; Mice ; Mice, Transgenic ; Viral Proteins/genetics
    Chemical Substances Antigens, Viral, Tumor ; Capsid Proteins ; Viral Proteins
    Language English
    Publishing date 2021-01-22
    Publishing country Switzerland
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 2516098-9
    ISSN 1999-4915 ; 1999-4915
    ISSN (online) 1999-4915
    ISSN 1999-4915
    DOI 10.3390/v13020162
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Antigen Retrieval and Signal Amplification.

    Dunkenberger, Logan / Del Valle, Luis

    Methods in molecular biology (Clifton, N.J.)

    2021  Volume 2422, Page(s) 65–74

    Abstract: Immunohistochemistry (IHC) offers a valuable method for determining the spatial distribution of proteins in cells and tissues. Fixation of tissues prior IHC enables their long-term stability and preserves tissue morphology; however, downstream analysis ... ...

    Abstract Immunohistochemistry (IHC) offers a valuable method for determining the spatial distribution of proteins in cells and tissues. Fixation of tissues prior IHC enables their long-term stability and preserves tissue morphology; however, downstream analysis of protein localization within fixed samples can be complicated by cross-links formed between proteins during formalin fixation which mask target epitopes. Antigen Retrieval (AR) is a process introduced to reverse such cross-links, improving the sensitivity of antibody-based protein detection, and can be performed using protease- or heat-based approaches. Even following AR, low abundance target proteins may require additional amplification for sensitive visualization. The development of amplification approaches such as the use of biotinylated secondary antibodies with avidin-biotin complex and tyramide signal amplification greatly improve the sensitivity of IHC, enabling a wider range of epitopes to be detected when coupled with AR.
    MeSH term(s) Antigens ; Avidin ; Epitopes ; Formaldehyde ; Immunohistochemistry ; Tissue Fixation
    Chemical Substances Antigens ; Epitopes ; Avidin (1405-69-2) ; Formaldehyde (1HG84L3525)
    Language English
    Publishing date 2021-12-02
    Publishing country United States
    Document type Journal Article
    ISSN 1940-6029
    ISSN (online) 1940-6029
    DOI 10.1007/978-1-0716-1948-3_5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Lanthanides-Substituted Hydroxyapatite for Biomedical Applications.

    De Lama-Odría, María Del Carmen / Valle, Luis J Del / Puiggalí, Jordi

    International journal of molecular sciences

    2023  Volume 24, Issue 4

    Abstract: Lately, there has been an increasing demand for materials that could improve tissue regenerative therapies and provide antimicrobial effects. Similarly, there is a growing need to develop or modify biomaterials for the diagnosis and treatment of ... ...

    Abstract Lately, there has been an increasing demand for materials that could improve tissue regenerative therapies and provide antimicrobial effects. Similarly, there is a growing need to develop or modify biomaterials for the diagnosis and treatment of different pathologies. In this scenario, hydroxyapatite (HAp) appears as a bioceramic with extended functionalities. Nevertheless, there are certain disadvantages related to the mechanical properties and lack of antimicrobial capacity. To circumvent them, the doping of HAp with a variety of cationic ions is emerging as a good alterative due to the different biological roles of each ion. Among many elements, lanthanides are understudied despite their great potential in the biomedical field. For this reason, the present review focuses on the biological benefits of lanthanides and how their incorporation into HAp can alter its morphology and physical properties. A comprehensive section of the applications of lanthanides-substituted HAp nanoparticles (HAp NPs) is presented to unveil the potential biomedical uses of these systems. Finally, the need to study the tolerable and non-toxic percentages of substitution with these elements is highlighted.
    MeSH term(s) Durapatite ; Lanthanoid Series Elements ; Biocompatible Materials ; Nanoparticles
    Chemical Substances Durapatite (91D9GV0Z28) ; Lanthanoid Series Elements ; Biocompatible Materials
    Language English
    Publishing date 2023-02-08
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms24043446
    Database MEDical Literature Analysis and Retrieval System OnLINE

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