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  1. Book: Approaching global oncology

    Elzawawy, Ahmed / Ngwa, Wilfred

    the win-win model

    (IOP series in global health and radiation oncology ; IOP ebooks)

    2022  

    Author's details edited by Ahmed Elzawawy, Wilfred Ngwa
    Series title IOP series in global health and radiation oncology
    IOP ebooks
    Keywords Oncology ; Cancer/Treatment
    Subject code 616.994
    Language English
    Size L, 402 Seiten, Illustrationen, 26 cm
    Publisher IOP Publishing
    Publishing place Bristol
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT021450619
    ISBN 978-0-7503-3073-2 ; 978-0-7503-3076-3 ; 9780750330756 ; 9780750330749 ; 0-7503-3073-2 ; 0-7503-3076-7 ; 0750330759 ; 0750330740
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2022 A 975 available for loan (reading room) Lesesaal EG

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  2. Article ; Online: The role of Black people in ending systemic racism in oncology.

    Ngwa, Wilfred

    The Lancet. Oncology

    2021  Volume 22, Issue 2, Page(s) 172

    MeSH term(s) African Americans/psychology ; European Continental Ancestry Group/psychology ; Humans ; Medical Oncology/ethics ; Racism/ethics
    Language English
    Publishing date 2021-01-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 2049730-1
    ISSN 1474-5488 ; 1470-2045
    ISSN (online) 1474-5488
    ISSN 1470-2045
    DOI 10.1016/S1470-2045(21)00016-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5696: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 460: Show issues

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  3. Article ; Online: Systemic immune effects boost radiotherapy.

    Ngwa, Wilfred

    Nature biomedical engineering

    2018  Volume 2, Issue 8, Page(s) 562–563

    MeSH term(s) Animals ; Humans ; Immunotherapy ; Mice ; Neoplasms/immunology ; Neoplasms/therapy ; Radiotherapy
    Language English
    Publishing date 2018-03-26
    Publishing country England
    Document type Journal Article
    ISSN 2157-846X
    ISSN (online) 2157-846X
    DOI 10.1038/s41551-018-0264-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Modelling treatment-response rates.

    Grassberger, Clemens / Ngwa, Wilfred

    Nature biomedical engineering

    2021  Volume 5, Issue 4, Page(s) 295–296

    MeSH term(s) Humans ; Models, Theoretical ; Tumor Burden
    Language English
    Publishing date 2021-04-16
    Publishing country England
    Document type Journal Article ; Comment
    ISSN 2157-846X
    ISSN (online) 2157-846X
    DOI 10.1038/s41551-021-00717-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Global democratisation of proton radiotherapy.

    Yan, Susu / Ngoma, Twalib A / Ngwa, Wilfred / Bortfeld, Thomas R

    The Lancet. Oncology

    2023  Volume 24, Issue 6, Page(s) e245–e254

    Abstract: Proton radiotherapy is an advanced treatment option compared with conventional x-ray treatment, delivering much lower doses of radiation to healthy tissues surrounding the tumour. However, proton therapy is currently not widely available. In this Review, ...

    Abstract Proton radiotherapy is an advanced treatment option compared with conventional x-ray treatment, delivering much lower doses of radiation to healthy tissues surrounding the tumour. However, proton therapy is currently not widely available. In this Review, we summarise the evolution of proton therapy to date, together with the benefits to patients and society. These developments have led to an exponential growth in the number of hospitals using proton radiotherapy worldwide. However, the gap between the number of patients who should be treated with proton radiotherapy and those who have access to it remains large. We summarise the ongoing research and development that is contributing to closing this gap, including the improvement of treatment efficiency and efficacy, and advances in fixed-beam treatments that do not require an enormously large, heavy, and costly gantry. The ultimate goal of decreasing the size of proton therapy machines to fit into standard treatment rooms appears to be within reach, and we discuss future research and development opportunities to achieve this goal.
    MeSH term(s) Humans ; Protons ; Proton Therapy ; Neoplasms/radiotherapy ; Radiotherapy Planning, Computer-Assisted ; Radiotherapy Dosage ; Radiotherapy
    Chemical Substances Protons
    Language English
    Publishing date 2023-05-30
    Publishing country England
    Document type Journal Article ; Review ; Research Support, N.I.H., Extramural
    ZDB-ID 2049730-1
    ISSN 1474-5488 ; 1470-2045
    ISSN (online) 1474-5488
    ISSN 1470-2045
    DOI 10.1016/S1470-2045(23)00184-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5696: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 460: Show issues

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  6. Article: Polydopamine Nanomaterials for Overcoming Current Challenges in Cancer Treatment.

    Acter, Shahinur / Moreau, Michele / Ivkov, Robert / Viswanathan, Akila / Ngwa, Wilfred

    Nanomaterials (Basel, Switzerland)

    2023  Volume 13, Issue 10

    Abstract: In efforts to overcome current challenges in cancer treatment, multifunctional nanoparticles are attracting growing interest, including nanoparticles made with polydopamine (PDA). PDA is a nature-inspired polymer with a dark brown color. It has excellent ...

    Abstract In efforts to overcome current challenges in cancer treatment, multifunctional nanoparticles are attracting growing interest, including nanoparticles made with polydopamine (PDA). PDA is a nature-inspired polymer with a dark brown color. It has excellent biocompatibility and is biodegradable, offering a range of extraordinary inherent advantages. These include excellent drug loading capability, photothermal conversion efficiency, and adhesive properties. Though the mechanism of dopamine polymerization remains unclear, PDA has demonstrated exceptional flexibility in engineering desired morphology and size, easy and straightforward functionalization, etc. Moreover, it offers enormous potential for designing multifunctional nanomaterials for innovative approaches in cancer treatment. The aim of this work is to review studies on PDA, where the potential to develop multifunctional nanomaterials with applications in photothermal therapy has been demonstrated. Future prospects of PDA for developing applications in enhancing radiotherapy and/or immunotherapy, including for image-guided drug delivery to boost therapeutic efficacy and minimal side effects, are presented.
    Language English
    Publishing date 2023-05-17
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662255-5
    ISSN 2079-4991
    ISSN 2079-4991
    DOI 10.3390/nano13101656
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: COVID-19 and cancer in Africa.

    Addai, Beatrice Wiafe / Ngwa, Wilfred

    Science (New York, N.Y.)

    2020  Volume 371, Issue 6524, Page(s) 25–27

    MeSH term(s) Africa/epidemiology ; Biomedical Research ; COVID-19/epidemiology ; COVID-19/prevention & control ; Communicable Disease Control ; Humans ; Neoplasms/diagnosis ; Neoplasms/prevention & control ; Neoplasms/therapy ; Telemedicine
    Language English
    Publishing date 2020-12-31
    Publishing country United States
    Document type Journal Article
    ZDB-ID 128410-1
    ISSN 1095-9203 ; 0036-8075
    ISSN (online) 1095-9203
    ISSN 0036-8075
    DOI 10.1126/science.abd1016
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 27: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MG 77: Show issues

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  8. Article: Phytoradiotherapy to enhance cancer treatment outcomes with cannabidiol, bitter melon juice, and plant hemoglobin.

    Alfonzetti, Tyler / Moreau, Michele / Yasmin-Karim, Sayeda / Ngwa, Wilfred / Avery, Stephen / Goia, Denisa

    Frontiers in oncology

    2023  Volume 12, Page(s) 1085686

    Abstract: Despite technological advances in radiation therapy for cancer treatment, many patient populations still experience mediocre survival percentages, local control, and quality of life. Additionally, much of the world lacks access to expensive, modern ... ...

    Abstract Despite technological advances in radiation therapy for cancer treatment, many patient populations still experience mediocre survival percentages, local control, and quality of life. Additionally, much of the world lacks access to expensive, modern treatment options. The need for innovative, cost-effective solutions that can improve patient treatment outcomes is essential. Phytomedicines have been shown to induce apoptotic tumor cell death, diminish tumor progression, reduce cancer incidence, alleviate harmful hypoxic conditions, and more. While an ample amount of research is available that characterizes many phytomedicines as having anti-cancer properties that increase tumor cell killing/control and mitigate the harmful side effects of radiation damage, little work has been done to investigate the synergistic effect of phytoradiotherapy: combining radiation treatment with phytomedicines. In this study, a protocol for testing the radiosensitizing effects of phytomedicines was validated and used to investigate the well-known plant based medicine cannabidiol (CBD) and the lesser-known medicinal fruit Bitter Melon. Additionally, based on its high concentration of plant hemoglobin which has been shown to abate hypoxia, the African-indigenous
    Language English
    Publishing date 2023-01-26
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2649216-7
    ISSN 2234-943X
    ISSN 2234-943X
    DOI 10.3389/fonc.2022.1085686
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Surface Immobilization of Anti-VEGF Peptide on SPIONs for Antiangiogenic and Targeted Delivery of Paclitaxel in Non-Small-Cell Lung Carcinoma.

    Ngema, Lindokuhle M / Adeyemi, Samson A / Marimuthu, Thashree / Ubanako, Philemon N / Ngwa, Wilfred / Choonara, Yahya E

    ACS applied bio materials

    2023  Volume 6, Issue 7, Page(s) 2747–2759

    Abstract: A design has been established for the surface decoration of superparamagnetic iron oxide nanoparticles (SPIONs) with anti-vascular endothelial growth factor peptide, HRH, to formulate a targeted paclitaxel (PTX) delivery nanosystem with notable tumor ... ...

    Abstract A design has been established for the surface decoration of superparamagnetic iron oxide nanoparticles (SPIONs) with anti-vascular endothelial growth factor peptide, HRH, to formulate a targeted paclitaxel (PTX) delivery nanosystem with notable tumor targetability and antiangiogenic activity. The design methodology included (i) tandem surface functionalization
    MeSH term(s) Humans ; Mice ; Animals ; Paclitaxel/pharmacology ; Paclitaxel/therapeutic use ; Carcinoma, Non-Small-Cell Lung/drug therapy ; Vascular Endothelial Growth Factor A ; Endothelial Cells ; Lung Neoplasms/drug therapy ; Cell Line, Tumor ; Peptides/chemistry ; Magnetic Iron Oxide Nanoparticles
    Chemical Substances Paclitaxel (P88XT4IS4D) ; Vascular Endothelial Growth Factor A ; Peptides
    Language English
    Publishing date 2023-06-29
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 2576-6422
    ISSN (online) 2576-6422
    DOI 10.1021/acsabm.3c00224
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Non-Cannabinoid Metabolites of

    Lowe, Henry / Steele, Blair / Bryant, Joseph / Toyang, Ngeh / Ngwa, Wilfred

    Plants (Basel, Switzerland)

    2021  Volume 10, Issue 2

    Abstract: The cannabis plant ( ...

    Abstract The cannabis plant (
    Language English
    Publishing date 2021-02-20
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2704341-1
    ISSN 2223-7747
    ISSN 2223-7747
    DOI 10.3390/plants10020400
    Database MEDical Literature Analysis and Retrieval System OnLINE

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