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  1. Article ; Online: Design and Synthesis of Novel 3-Nitro-1

    Pelizaro, Bruno I / Batista, Jaqueline C Z / Portapilla, Gisele B / das Neves, Amarith R / Silva, Fernanda / Carvalho, Diego B / Shiguemoto, Cristiane Y K / Pessatto, Lucas R / Paredes-Gamero, Edgar J / Cardoso, Iara A / Luccas, Pedro H / Nonato, M Cristina / Lopes, Norberto P / Galvão, Fernanda / Oliveira, Kelly M P / Cassemiro, Nadla S / Silva, Denise B / Piranda, Eliane M / Arruda, Carla C P /
    de Albuquerque, Sergio / Baroni, Adriano C M

    Journal of medicinal chemistry

    2024  Volume 67, Issue 4, Page(s) 2584–2601

    Abstract: A series of 28 compounds, 3-nitro- ... ...

    Abstract A series of 28 compounds, 3-nitro-1
    MeSH term(s) Humans ; Structure-Activity Relationship ; Trypanocidal Agents ; Chagas Disease/drug therapy ; Trypanosoma cruzi ; Triazoles/chemistry ; Leishmaniasis
    Chemical Substances 1,2,4-triazole (288-88-0) ; Trypanocidal Agents ; Triazoles
    Language English
    Publishing date 2024-02-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 218133-2
    ISSN 1520-4804 ; 0022-2623
    ISSN (online) 1520-4804
    ISSN 0022-2623
    DOI 10.1021/acs.jmedchem.3c01745
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 151: Show issues Location:
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  2. Article: Effects of Supplementing Milk Replacer with Sodium Butyrate on Dairy Calves.

    Belli, Anna Luiza / Coelho, Sandra G / Campolina, Joana P / Neves, Luiz F M / Neto, Hilton C Diniz / Silva, Camila S / Machado, Fernanda S / Pereira, Luiz Gustavo R / Tomich, Thierry R / Carvalho, Wanessa A / Costa, Suely de Fátima / M Campos, Mariana

    Animals : an open access journal from MDPI

    2024  Volume 14, Issue 2

    Abstract: Diarrhea and respiratory diseases pose significant challenges in the rearing of pre-weaned calves, motivating the investigation of tools to improve gastrointestinal tract development, health, and overall performance in young calves. Consequently, the ... ...

    Abstract Diarrhea and respiratory diseases pose significant challenges in the rearing of pre-weaned calves, motivating the investigation of tools to improve gastrointestinal tract development, health, and overall performance in young calves. Consequently, the primary objective of this study was to assess the effectiveness of an additive incorporated into milk replacer to promote the development and health of the animals. Forty-six dairy calves were randomly assigned into two treatments: control (CON,
    Language English
    Publishing date 2024-01-16
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2606558-7
    ISSN 2076-2615
    ISSN 2076-2615
    DOI 10.3390/ani14020277
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Overweight Impairs Postural Control of Female Night Workers.

    Narciso, Fernanda Veruska / Dâmaso, Ana R / Barela, Jose A / Carvalho, Adriana N S / Ruiz, Francieli / de Queiroz, Sandra Souza / Lemos, Vanessa Silva / de-Andrade, Andre Gustavo P / Tufik, Sergio / De-Mello, Marco Túlio

    Sleep science (Sao Paulo, Brazil)

    2023  Volume 16, Issue 1, Page(s) 29–37

    Abstract: ... ...

    Abstract Objectives
    Language English
    Publishing date 2023-04-19
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2697016-8
    ISSN 1984-0063 ; 1984-0659
    ISSN (online) 1984-0063
    ISSN 1984-0659
    DOI 10.1055/s-0043-1767746
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Analysis of the association between high workload and musculoskeletal pain in public school teachers according to physical activity level.

    Furuta, Debora T / Tebar, William R / Beretta, Victor S / Tebar, Fernanda Gil / de Carvalho, Augusto C / Leoci, Isabella C / Delfino, Leandro D / Ferrari, Gerson / Silva, Claudiele C M / Christofaro, Diego G D

    Work (Reading, Mass.)

    2024  

    Abstract: Background: A high workload has been associated with musculoskeletal pain in public school teachers. However, the hypothesis of the present study was that physical activity (PA) practice is able to attenuate this association.: Objective: To analyze ... ...

    Abstract Background: A high workload has been associated with musculoskeletal pain in public school teachers. However, the hypothesis of the present study was that physical activity (PA) practice is able to attenuate this association.
    Objective: To analyze the associations between high workload with musculoskeletal pain according to PA levels in public school teachers.
    Methods: Teachers (n = 239) from 13 public schools were evaluated. Workload was assessed using a Likert scale in which teachers reported their perception of their work routine as: very low, low, regular, high, and very high. Musculoskeletal pain and PA were assessed using questionnaires. Multivariate logistic regression models were used to investigate the association of high workload with PA levels and musculoskeletal pain in different body regions, compared to participants with normal workload, adjusted by sex, age, and socioeconomic status.
    Results: A high workload was associated with higher chances of reporting pain in the wrists and hands (OR = 3.55; 95% CI = 1.27-9.89), knee (OR = 3.09; 95CI%  = 1.09-8.82), and feet and ankles (OR = 3.16; 95% CI = 1.03-9.76) in less active teachers. However, these associations were not observed in teachers considered more active.
    Conclusion: PA practice is able to act as a good protector against musculoskeletal pain in teachers, even in individuals with a high workload.
    Language English
    Publishing date 2024-02-22
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1394194-x
    ISSN 1875-9270 ; 1051-9815
    ISSN (online) 1875-9270
    ISSN 1051-9815
    DOI 10.3233/WOR-230474
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4810: Show issues Location:
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  5. Article ; Online: Analysis of the Genomic Features and Evolutionary History of Pithovirus-Like Isolates Reveals Two Major Divergent Groups of Viruses.

    Queiroz, Victória F / Carvalho, João Victor R P / de Souza, Fernanda G / Lima, Maurício T / Santos, Juliane D / Rocha, Kamila L S / de Oliveira, Danilo B / Araújo, João Pessoa / Ullmann, Leila Sabrina / Rodrigues, Rodrigo A L / Abrahão, Jônatas S

    Journal of virology

    2023  Volume 97, Issue 7, Page(s) e0041123

    Abstract: New representatives of the ... ...

    Abstract New representatives of the phylum
    MeSH term(s) Humans ; Genome, Viral/genetics ; Genomics ; Giant Viruses/classification ; Giant Viruses/genetics ; Phylogeny ; Genetic Variation ; Evolution, Molecular
    Language English
    Publishing date 2023-07-03
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 80174-4
    ISSN 1098-5514 ; 0022-538X
    ISSN (online) 1098-5514
    ISSN 0022-538X
    DOI 10.1128/jvi.00411-23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  6. Article ; Online: SARS CoV-2 infection among Healthcare Workers from different public health units in Brazil.

    de Oliveira, Fátima de Cássia E / Silva, Maria Francilene S / Fernandes, Maria da Conceição R / Garcia, Max Moreira L / Dinelly Pinto, Ana Carolina M / Severino, Fernanda Gadelha / Alves, Jamille Soares Moreira / Fonseca, Carlos Augusto Guimarães / de Carvalho Araújo, Fernanda Montenegro / de Andrade, Luiz Odorico Monteiro / Gambim Fonseca, Marcela H

    Molecular immunology

    2023  Volume 163, Page(s) 13–19

    Abstract: Understanding COVID-19 exposure differences among Healthcare Workers (HCWs) across various healthcare units is crucial for their protection and effective management of future outbreaks. However, comparative data on COVID-19 among HCWs in different ... ...

    Abstract Understanding COVID-19 exposure differences among Healthcare Workers (HCWs) across various healthcare units is crucial for their protection and effective management of future outbreaks. However, comparative data on COVID-19 among HCWs in different healthcare units are scarce in Brazil. This study evaluated the relationship between SARS-CoV-2 infection and workplaces in HCWs from three distinct healthcare settings in Brazil. It also examined COVID-19 symptom dynamics reported by them. The cohort comprised 464 HCWs vaccinated with two doses of CoronaVac and a BNT162b2 booster from different institutions: Primary Health Care Units (PHCUs), Emergency Care Units (ECUs), and Hospitals. Participants answered a questionnaire and underwent blood collection at various time points after vaccinations. RT-PCR data and post-vaccination antibody responses were utilized as indicators of SARS-CoV-2 infection. We found that most infected HCWs worked in ECUs, where positive RT-PCR percentages were higher compared to PHCUs and Hospitals. ECUs also showed the highest seropositivity and antibody levels, especially after the first CoronaVac dose. The second dose of CoronaVac diminished the differences in the antibody levels among HCWs from ECUS, PHCUs, and Hospitals, indicating the benefit of the second dose to equalize the antibody levels between previously exposed and unexposed persons. Moreover, COVID-19 symptoms appeared to evolve over time.
    MeSH term(s) Humans ; Public Health ; Brazil/epidemiology ; BNT162 Vaccine ; COVID-19 ; SARS-CoV-2 ; Health Personnel ; Antibodies, Viral
    Chemical Substances sinovac COVID-19 vaccine ; BNT162 Vaccine ; Antibodies, Viral
    Language English
    Publishing date 2023-09-15
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 424427-8
    ISSN 1872-9142 ; 0161-5890
    ISSN (online) 1872-9142
    ISSN 0161-5890
    DOI 10.1016/j.molimm.2023.09.001
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 166: Show issues Location:
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  7. Article ; Online: Analysis of 12 X-STRs loci in a population from southeastern Brazil.

    Garcia, Fernanda M / Trabach, Raquel S R / Stange, Victor S / Cancian, Bruno / Zetum, Alexia S S / Casotti, Matheus C / Errera, Flavia I V / de Carvalho, Elizeu F / Meira, Débora D / Louro, Iuri D

    Forensic science international. Genetics

    2023  Volume 68, Page(s) 102974

    Abstract: Short tandem repeat (STR) markers on the X chromosome have a high potential for solving complex kinship analysis and individual identification cases. To achieve such purposes, allele and haplotype frequencies for the specific population are necessary. ... ...

    Abstract Short tandem repeat (STR) markers on the X chromosome have a high potential for solving complex kinship analysis and individual identification cases. To achieve such purposes, allele and haplotype frequencies for the specific population are necessary. Nonetheless, such frequencies are not always available. Therefore, we obtained haplotypes from 520 unrelated males from four different geographic regions of Espírito Santo - Brazil, using the Investigator Argus X-12 kit. Forensic parameters for linked groups of four X-STR loci are reported. Genetic distance analyzes suggest that ES population is genetically closer to the Italian population and farther from the Mexican one, among the populations analyzed in this study.
    MeSH term(s) Male ; Humans ; Genetics, Population ; Brazil ; Haplotypes ; Chromosomes, Human, X ; Microsatellite Repeats ; Gene Frequency ; DNA Fingerprinting
    Language English
    Publishing date 2023-11-02
    Publishing country Netherlands
    Document type Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 2493339-9
    ISSN 1878-0326 ; 1872-4973
    ISSN (online) 1878-0326
    ISSN 1872-4973
    DOI 10.1016/j.fsigen.2023.102974
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    Zs.A 6764: Show issues Location:
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  8. Article: Licury Cake in Diets for Lactating Goats: Intake, Digestibility, Feeding Behavior, Milk Production and Composition, and Nitrogen Metabolism.

    Ferreira, Fernanda G / Leite, Laudí C / Alba, Henry D R / Pina, Douglas Dos S / Santos, Stefanie A / Tosto, Manuela S L / Rodrigues, Carlindo S / Silva, Robério R / de Freitas Júnior, José E / Mesquita, Bruna M A de C / Carvalho, Gleidson G P de

    Animals : an open access journal from MDPI

    2023  Volume 13, Issue 15

    Abstract: The objective of this study was to determine the effects of licury cake (LC) inclusion in the diets of lactating goats on productive and metabolic performance. Twelve lactating goats, eight Saanen and four Anglo-Nubian, were distributed in a triplicate 4 ...

    Abstract The objective of this study was to determine the effects of licury cake (LC) inclusion in the diets of lactating goats on productive and metabolic performance. Twelve lactating goats, eight Saanen and four Anglo-Nubian, were distributed in a triplicate 4 × 4 Latin square design, with four treatments (0, 66.7, 133.3, and 200 g kg
    Language English
    Publishing date 2023-08-06
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2606558-7
    ISSN 2076-2615
    ISSN 2076-2615
    DOI 10.3390/ani13152535
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  9. Article ; Online: Potential of Solar UV Radiation for Inactivation of Coronaviridae Family Estimated from Satellite Data.

    Carvalho, Fernanda R S / Henriques, Diamantino V / Correia, Osvaldo / Schmalwieser, Alois W

    Photochemistry and photobiology

    2020  Volume 97, Issue 1, Page(s) 213–220

    Abstract: The pandemic COVID-19 disease affects people dramatically overall the globe by illness and death. Several strategies are applied to restrict the spread of this disease such as lockdown, adequate social distance in different activities, hand disinfection ... ...

    Abstract The pandemic COVID-19 disease affects people dramatically overall the globe by illness and death. Several strategies are applied to restrict the spread of this disease such as lockdown, adequate social distance in different activities, hand disinfection and the use of masks. Potential hazard outdoors comes from released viruses, which may remain in the air for a while and settle down afterward and contaminating surfaces. Solar ultraviolet radiation (UVR) is known to act as a natural environmental virucide. The virucidal effectivity of UVR depends on a first order on the sensitivity of the virus against UVR as well as on the amount of incoming UVR. Here, we present estimates of the potential of solar UVR in inactivating SARS-CoV-2 in the environment. This is done by combining DNA-damaging surface solar UVR retrieved by satellites and the available information on fluence for inactivation of Coronaviridae. Our results show that solar UVR has a high potential to inactivate these viruses, but the degree depends strongly on location and season. In the subtropics (Sao Paulo, 23.5°S), the daily survival fraction is lower than 10
    MeSH term(s) COVID-19/epidemiology ; COVID-19/virology ; Coronavirus/radiation effects ; SARS-CoV-2 ; Seasons ; Sunlight ; Ultraviolet Rays
    Keywords covid19
    Language English
    Publishing date 2020-11-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 123540-0
    ISSN 1751-1097 ; 0031-8655
    ISSN (online) 1751-1097
    ISSN 0031-8655
    DOI 10.1111/php.13345
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    Zs.B 1686: Show issues Location:
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  10. Article: Tuning the Biological Activity of Camphorimine Complexes through Metal Selection.

    Costa, Joana P / Pinheiro, Teresa / Martins, Maria S / Carvalho, M Fernanda N N / Feliciano, Joana R / Leitão, Jorge H / Silva, Rafaela A L / Guerreiro, Joana F / Alves, Luís M C / Custódio, Inês / Cruz, João / Marques, Fernanda

    Antibiotics (Basel, Switzerland)

    2022  Volume 11, Issue 8

    Abstract: The cytotoxic activity of four sets of camphorimine complexes based on the Cu(I), Cu(II), Ag(I), and Au(I) metal sites were assessed against the cisplatin-sensitive A2780 and OVCAR3 ovarian cancer cells. The results showed that the gold complexes were ca. ...

    Abstract The cytotoxic activity of four sets of camphorimine complexes based on the Cu(I), Cu(II), Ag(I), and Au(I) metal sites were assessed against the cisplatin-sensitive A2780 and OVCAR3 ovarian cancer cells. The results showed that the gold complexes were ca. one order of magnitude more active than the silver complexes, which in turn were ca. one order of magnitude more active than the copper complexes. An important finding was that the cytotoxic activity of the Ag(I) and Au(I) camphorimine complexes was higher than that of cisplatin. Another relevant aspect was that the camphorimine complexes did not interact significantly with DNA, in contrast with cisplatin. The cytotoxic activity of the camphorimine complexes displayed a direct relationship with the cellular uptake by OVCAR3 cells, as ascertained by PIXE (particle-induced X-ray emission). The levels of ROS (reactive oxygen species) formation exhibited an inverse relationship with the reduction potentials for the complexes with the same metal, as assessed by cyclic voltammetry. In order to gain insight into the toxicity of the complexes, their cytotoxicity toward nontumoral cells (HDF and V79 fibroblasts) was evaluated. The in vivo cytotoxicity of complex
    Language English
    Publishing date 2022-07-27
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2681345-2
    ISSN 2079-6382
    ISSN 2079-6382
    DOI 10.3390/antibiotics11081010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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