LIVIVO - Search results -

Search results

Result 1 - 10 of total 3423

Search options

Article ; Online: Are we underestimating the potential of neuroactive drugs to augment neuromotor function in sarcopenia?

Orssatto, Lucas B R / Thorstensen, Jacob R / Scott, David / Daly, Robin M

2024 Volume 154, Page(s) 155816

MeSH term(s)	Humans ; Sarcopenia/drug therapy ; Aging ; Muscle, Skeletal
Language	English
Publishing date	2024-02-15
Publishing country	United States
Document type	Editorial
ZDB-ID	80230-x
ISSN	1532-8600 ; 0026-0495
ISSN (online)	1532-8600
ISSN	0026-0495
DOI	10.1016/j.metabol.2024.155816
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Uc I Zs.316: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Sleep Apnea, Obesity, and Readmissions: Real Risks or Residual Confounding?

Donovan, Lucas M / Au, David H

Annals of the American Thoracic Society

2022 Volume 19, Issue 3, Page(s) 361–362

MeSH term(s)	Humans ; Obesity/epidemiology ; Patient Readmission ; Sleep Apnea Syndromes/epidemiology ; Sleep Apnea Syndromes/therapy
Language	English
Publishing date	2022-03-01
Publishing country	United States
Document type	Editorial ; Research Support, U.S. Gov't, Non-P.H.S. ; Comment
ZDB-ID	2717461-X
ISSN	2325-6621 ; 1943-5665 ; 2325-6621
ISSN (online)	2325-6621 ; 1943-5665
ISSN	2325-6621
DOI	10.1513/AnnalsATS.202111-1304ED
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 5828: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: When less is more: Updates in active surveillance and watchful waiting in the management of prostate cancer.

Homewood, David / Lucas, Harrison / Kennedy, Caitlin / Majer, James / Sathianathen, Niranjan / Corcoran, Niall M

Australian journal of general practice

2024 Volume 53, Issue 5, Page(s) 253–257

Abstract: Background: Prostate cancer is the second most common cancer among men globally. A range of management options are available for prostate cancer, including surgery, radiation therapy, hormone therapy, chemotherapy, or surveillance. Conservative ... ...

Abstract	Background: Prostate cancer is the second most common cancer among men globally. A range of management options are available for prostate cancer, including surgery, radiation therapy, hormone therapy, chemotherapy, or surveillance. Conservative strategies include active surveillance and watchful waiting, which differ in their intent. Objective: We provide a targeted instructive management algorithm for improving understanding of conservative strategies in prostate cancer. Discussion: Active surveillance involves close monitoring with curative intent when there is evidence of disease progression. In contrast, watchful waiting is palliative in intent and focuses on delaying treatment until symptoms or complications develop. Conservative approaches have demonstrated similar long-term oncological outcomes to radical treatment, while reducing harm from overtreatment, and maintaining quality of life by avoiding potential side effects such as urinary incontinence and erectile dysfunction. The decision to employ a conservative approach is determined by both patient and disease factors. Conservative management strategies play a vital role in the management of prostate cancer.
MeSH term(s)	Humans ; Male ; Watchful Waiting/methods ; Prostatic Neoplasms/therapy ; Disease Progression ; Quality of Life/psychology
Language	English
Publishing date	2024-05-02
Publishing country	Australia
Document type	Journal Article
ZDB-ID	2924889-9
ISSN	2208-7958 ; 2208-794X
ISSN (online)	2208-7958
ISSN	2208-794X
DOI	10.31128/AJGP-06-23-6866
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.B 2235: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Severe cerebral palsy survival is similar in California, USA and Victoria, Australia.

Walz, Lucas / Brooks, Jordan C / Strauss, David J / Shavelle, Robert M

Developmental medicine and child neurology

2023 Volume 65, Issue 11, Page(s) 1532–1533

MeSH term(s)	Humans ; Victoria ; Cerebral Palsy/epidemiology ; California
Language	English
Publishing date	2023-04-10
Publishing country	England
Document type	Letter ; Comment
ZDB-ID	80369-8
ISSN	1469-8749 ; 0012-1622
ISSN (online)	1469-8749
ISSN	0012-1622
DOI	10.1111/dmcn.15616
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.B 5: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Resolving Hidden Solution Conformations of Hemoglobin Using IMS-IMS on a Cyclic Instrument.

Sharon, Edie M / Henderson, Lucas W / Clemmer, David E

Journal of the American Society for Mass Spectrometry

2023 Volume 34, Issue 8, Page(s) 1559–1568

Abstract: Ion mobility spectrometry-mass spectrometry (IMS-MS) experiments on a cyclic IMS instrument were used to examine heterogeneous distributions of structures found in the 15+ to 18+ charge states of the hemoglobin tetramer (Hb). The resolving power of IMS ... ...

Abstract	Ion mobility spectrometry-mass spectrometry (IMS-MS) experiments on a cyclic IMS instrument were used to examine heterogeneous distributions of structures found in the 15+ to 18+ charge states of the hemoglobin tetramer (Hb). The resolving power of IMS measurements is known to increase with increasing drift-region length. This effect is not significant for Hb charge states as peaks were shown to broaden with increasing drift-region length. This observation suggests that multiple structures with similar cross sections may be present. To examine this hypothesis, selections of drift time distributions were isolated and subsequently reinjected into the mobility region for additional separation. These IMS-IMS experiments demonstrate that selected regions separate further upon additional passes around the drift cell, consistent with the idea that initial resolving power was limited due to the presence of many closely related conformations. Additional variable temperature electrospray ionization (vT-ESI) experiments were conducted to study how changing the solution temperature affects solution conformations. Some features in these IMS-IMS studies were observed to change similarly with solution temperature compared to features in the single IMS distribution. Other features changed differently in the selected mobility data, indicating that solution structures that were obscured upon IMS analysis because of the complex heterogeneity of the original distribution are discernible after reducing the number of conformers that are analyzed by further IMS analysis. These results illustrate that the combination of vT-ESI with IMS-IMS is useful for resolving and exploring conformer distributions and stabilities in systems that exhibit a large degree of structural heterogeneity.
MeSH term(s)	Mass Spectrometry/methods ; Molecular Conformation ; Ion Mobility Spectrometry ; Temperature ; Hemoglobins
Chemical Substances	Hemoglobins
Language	English
Publishing date	2023-07-07
Publishing country	United States
Document type	Journal Article
ZDB-ID	1073671-2
ISSN	1879-1123 ; 1044-0305
ISSN (online)	1879-1123
ISSN	1044-0305
DOI	10.1021/jasms.3c00032
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 4618: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 241: Show issues

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Earlier social information has a stronger influence on judgments

Alan Novaes Tump / David Wollny-Huttarsch / Lucas Molleman / Ralf H. J. M. Kurvers

Scientific Reports, Vol 14, Iss 1, Pp 1-

2024 Volume 13

Abstract: Abstract People’s decisions are often informed by the choices of others. Evidence accumulation models provide a mechanistic account of how such social information enters the choice process. Previous research taking this approach has suggested two ... ...

Abstract	Abstract People’s decisions are often informed by the choices of others. Evidence accumulation models provide a mechanistic account of how such social information enters the choice process. Previous research taking this approach has suggested two fundamentally different cognitive mechanisms by which people incorporate social information. On the one hand, individuals may update their evidence level instantaneously when observing social information. On the other hand, they may gradually integrate social information over time. These accounts make different predictions on how the timing of social information impacts its influence. The former predicts that timing has no impact on social information uptake. The latter predicts that social information which arrives earlier has a stronger impact because its impact increases over time. We tested both predictions in two studies in which participants first observed a perceptual stimulus. They then entered a deliberation phase in which social information arrived either early or late before reporting their judgment. In Experiment 1, early social information remained visible until the end and was thus displayed for longer than late social information. In Experiment 2, which was preregistered, early and late social information were displayed for an equal duration. In both studies, early social information had a larger impact on individuals’ judgments. Further, an evidence accumulation analysis found that social information integration was best explained by both an immediate update of evidence and continuous integration over time. Because in social systems, timing plays a key role (e.g., propagation of information in social networks), our findings inform theories explaining the temporal evolution of social impact and the emergent social dynamics.
Keywords	Medicine ; R ; Science ; Q
Subject code	306 ; 300
Language	English
Publishing date	2024-01-01T00:00:00Z
Publisher	Nature Portfolio
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: The propagation of disturbances in ecological networks.

Martins, Lucas P / Garcia-Callejas, David / Lai, Hao Ran / Wootton, Kate L / Tylianakis, Jason M

Trends in ecology & evolution

2024

Abstract: Despite the development of network science, we lack clear heuristics for how far different disturbance types propagate within and across species interaction networks. We discuss the mechanisms of disturbance propagation in ecological networks, and ... ...

Abstract	Despite the development of network science, we lack clear heuristics for how far different disturbance types propagate within and across species interaction networks. We discuss the mechanisms of disturbance propagation in ecological networks, and propose that disturbances can be categorized into structural, functional, and transmission types according to their spread and effect on network structure and functioning. We describe the properties of species and their interaction networks and metanetworks that determine the indirect, spatial, and temporal extent of propagation. We argue that the sampling scale of ecological studies may have impeded predictions regarding the rate and extent that a disturbance spreads, and discuss directions to help ecologists to move towards a predictive understanding of the propagation of impacts across interacting communities and ecosystems.
Language	English
Publishing date	2024-02-23
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	284965-3
ISSN	1872-8383 ; 0169-5347
ISSN (online)	1872-8383
ISSN	0169-5347
DOI	10.1016/j.tree.2024.01.009
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Bonn / Germany

Zs Bio TEE: Show issues
Z 2005/711: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾
- See ZB MED holdings
- Order with fees

Article: The spiking output of the mouse olfactory bulb encodes large-scale temporal features of natural odor environments.

Lewis, Suzanne M / Suarez, Lucas M / Rigolli, Nicola / Steinmetz, Nicholas A / Gire, David H

bioRxiv : the preprint server for biology

2024

Abstract: Spatiotemporal dynamics of natural odor environment have informative features for animals navigating to an odor source. Population activity in the olfactory bulb (OB) has been shown to follow plume dynamics to a moderate degree (Lewis et al., 2021), but ... ...

Abstract	Spatiotemporal dynamics of natural odor environment have informative features for animals navigating to an odor source. Population activity in the olfactory bulb (OB) has been shown to follow plume dynamics to a moderate degree (Lewis et al., 2021), but it is unknown whether the ability to follow plume dynamics is driven by individual cells or whether it emerges at the population level. Previous research has explored the responses of individual OB cells to isolated features of plumes, but it is difficult to adequately sample these features as it is still undetermined which features navigating mice employ during olfactory guided search. Here we released odor from an upwind odor source and simultaneously recorded both odor concentration dynamics and cellular response dynamics in awake, head-fixed mice. We found that longer timescale features of odor concentration dynamics were encoded at both the cellular and population level. At the cellular level, plume onset was encoded across all trials and plume offset was encoded for high concentration odors, but not low concentration odors. Although cellular level tracking of plume dynamics was observed to be weak, we found that at the population level, OB activity distinguished whiffs and blanks (accurately detected odor presence versus absence) throughout the duration of a plume. Even ~20 OB cells were enough to accurately encode these features. Our findings indicate that the full range of odor concentration dynamics and high frequency fluctuations are not encoded by OB spiking activity. Instead, relatively lower-frequency dynamics of plumes, such as plume onset, plume offset, whiffs, and blanks, are represented in the OB.
Language	English
Publishing date	2024-03-05
Publishing country	United States
Document type	Preprint
DOI	10.1101/2024.03.01.582978
Database	MEDical Literature Analysis and Retrieval System OnLINE

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾

Article ; Online: Earlier social information has a stronger influence on judgments.

Tump, Alan Novaes / Wollny-Huttarsch, David / Molleman, Lucas / Kurvers, Ralf H J M

Scientific reports

2024 Volume 14, Issue 1, Page(s) 105

Abstract: People's decisions are often informed by the choices of others. Evidence accumulation models provide a mechanistic account of how such social information enters the choice process. Previous research taking this approach has suggested two fundamentally ... ...

Abstract	People's decisions are often informed by the choices of others. Evidence accumulation models provide a mechanistic account of how such social information enters the choice process. Previous research taking this approach has suggested two fundamentally different cognitive mechanisms by which people incorporate social information. On the one hand, individuals may update their evidence level instantaneously when observing social information. On the other hand, they may gradually integrate social information over time. These accounts make different predictions on how the timing of social information impacts its influence. The former predicts that timing has no impact on social information uptake. The latter predicts that social information which arrives earlier has a stronger impact because its impact increases over time. We tested both predictions in two studies in which participants first observed a perceptual stimulus. They then entered a deliberation phase in which social information arrived either early or late before reporting their judgment. In Experiment 1, early social information remained visible until the end and was thus displayed for longer than late social information. In Experiment 2, which was preregistered, early and late social information were displayed for an equal duration. In both studies, early social information had a larger impact on individuals' judgments. Further, an evidence accumulation analysis found that social information integration was best explained by both an immediate update of evidence and continuous integration over time. Because in social systems, timing plays a key role (e.g., propagation of information in social networks), our findings inform theories explaining the temporal evolution of social impact and the emergent social dynamics.
MeSH term(s)	Humans ; Judgment
Language	English
Publishing date	2024-01-02
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-023-50345-4
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Stability of 20S Proteasome Configurations: Preopening the Axial Gate.

Henderson, Lucas W / Sharon, Edie M / Gautam, Amit K S / Anthony, Adam J / Jarrold, Martin F / Russell, David H / Matouschek, Andreas / Clemmer, David E

The journal of physical chemistry letters

2023 Volume 14, Issue 21, Page(s) 5014–5017

Abstract: Mass spectrometry studies of the stability of ... ...

Abstract	Mass spectrometry studies of the stability of the
MeSH term(s)	Proteasome Endopeptidase Complex/chemistry ; Proteasome Endopeptidase Complex/metabolism ; Saccharomyces cerevisiae/metabolism ; Proteolysis
Chemical Substances	Proteasome Endopeptidase Complex (EC 3.4.25.1)
Language	English
Publishing date	2023-05-24
Publishing country	United States
Document type	Journal Article
ISSN	1948-7185
ISSN (online)	1948-7185
DOI	10.1021/acs.jpclett.3c01040
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

To top

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

Inter-library loan at ZB MED