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  1. Article ; Online: Stroke in hypertrophic cardiomyopathy. Never mind the rhythm.

    Pieroni, Maurizio / Ciabatti, Michele / Bolognese, Leonardo

    International journal of cardiology

    2023  Volume 385, Page(s) 41–42

    MeSH term(s) Humans ; Cardiomyopathy, Hypertrophic ; Stroke ; Stroke Volume
    Language English
    Publishing date 2023-05-25
    Publishing country Netherlands
    Document type Editorial ; Comment
    ZDB-ID 779519-1
    ISSN 1874-1754 ; 0167-5273
    ISSN (online) 1874-1754
    ISSN 0167-5273
    DOI 10.1016/j.ijcard.2023.05.043
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    Zs.A 1673: Show issues Location:
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  2. Article ; Online: Fabry disease in patients with pacemaker: A needle in a haystack?

    Pieroni, Maurizio / Zocchi, Chiara / Ciabatti, Michele

    International journal of cardiology

    2023  Volume 377, Page(s) 89–90

    MeSH term(s) Humans ; Fabry Disease/diagnosis ; Pacemaker, Artificial/adverse effects
    Language English
    Publishing date 2023-01-11
    Publishing country Netherlands
    Document type Editorial ; Comment
    ZDB-ID 779519-1
    ISSN 1874-1754 ; 0167-5273
    ISSN (online) 1874-1754
    ISSN 0167-5273
    DOI 10.1016/j.ijcard.2023.01.006
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  3. Article ; Online: Anderson-Fabry disease management: role of the cardiologist.

    Pieroni, Maurizio / Namdar, Mehdi / Olivotto, Iacopo / Desnick, Robert J

    European heart journal

    2024  Volume 45, Issue 16, Page(s) 1395–1409

    Abstract: Anderson-Fabry disease (AFD) is a lysosomal storage disorder characterized by glycolipid accumulation in cardiac cells, associated with a peculiar form of hypertrophic cardiomyopathy (HCM). Up to 1% of patients with a diagnosis of HCM indeed have AFD. ... ...

    Abstract Anderson-Fabry disease (AFD) is a lysosomal storage disorder characterized by glycolipid accumulation in cardiac cells, associated with a peculiar form of hypertrophic cardiomyopathy (HCM). Up to 1% of patients with a diagnosis of HCM indeed have AFD. With the availability of targeted therapies for sarcomeric HCM and its genocopies, a timely differential diagnosis is essential. Specifically, the therapeutic landscape for AFD is rapidly evolving and offers increasingly effective, disease-modifying treatment options. However, diagnosing AFD may be difficult, particularly in the non-classic phenotype with prominent or isolated cardiac involvement and no systemic red flags. For many AFD patients, the clinical journey from initial clinical manifestations to diagnosis and appropriate treatment remains challenging, due to late recognition or utter neglect. Consequently, late initiation of treatment results in an exacerbation of cardiac involvement, representing the main cause of morbidity and mortality, irrespective of gender. Optimal management of AFD patients requires a dedicated multidisciplinary team, in which the cardiologist plays a decisive role, ranging from the differential diagnosis to the prevention of complications and the evaluation of timing for disease-specific therapies. The present review aims to redefine the role of cardiologists across the main decision nodes in contemporary AFD clinical care and drug discovery.
    MeSH term(s) Humans ; Cardiologists ; Fabry Disease/diagnosis ; Fabry Disease/drug therapy ; Cardiomyopathy, Hypertrophic/diagnosis ; Diagnosis, Differential
    Language English
    Publishing date 2024-03-14
    Publishing country England
    Document type Review ; Journal Article
    ZDB-ID 603098-1
    ISSN 1522-9645 ; 0195-668X
    ISSN (online) 1522-9645
    ISSN 0195-668X
    DOI 10.1093/eurheartj/ehae148
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    Zs.MO 640: Show issues

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  4. Article ; Online: Investigating the Photodynamics of

    Pieroni, Carlotta / Sangiogo Gil, Eduarda / Ibele, Lea M / Persico, Maurizio / Granucci, Giovanni / Agostini, Federica

    Journal of chemical theory and computation

    2024  Volume 20, Issue 2, Page(s) 580–596

    Abstract: In this work, we present the first implementation of coupled-trajectory Tully surface hopping (CT-TSH) suitable for applications to molecular systems. We combine CT-TSH with the semiempirical floating occupation molecular orbital-configuration ... ...

    Abstract In this work, we present the first implementation of coupled-trajectory Tully surface hopping (CT-TSH) suitable for applications to molecular systems. We combine CT-TSH with the semiempirical floating occupation molecular orbital-configuration interaction electronic structure method to investigate the photoisomerization dynamics of
    Language English
    Publishing date 2024-01-04
    Publishing country United States
    Document type Journal Article
    ISSN 1549-9626
    ISSN (online) 1549-9626
    DOI 10.1021/acs.jctc.3c00978
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  5. Article ; Online: Effect of Initial Conditions Sampling on Surface Hopping Simulations in the Ultrashort and Picosecond Time Range. Azomethane Photodissociation as a Case Study.

    Pieroni, Carlotta / Becuzzi, Filippo / Creatini, Luigi / Granucci, Giovanni / Persico, Maurizio

    Journal of chemical theory and computation

    2023  Volume 19, Issue 9, Page(s) 2430–2445

    Abstract: We tested the effect of different ways of sampling the initial conditions in surface hopping simulations, with a focus on the initial energy distributions and on the treatment of the zero point energy (ZPE). As a test case, we chose the gas phase ... ...

    Abstract We tested the effect of different ways of sampling the initial conditions in surface hopping simulations, with a focus on the initial energy distributions and on the treatment of the zero point energy (ZPE). As a test case, we chose the gas phase photodynamics of azomethane, which features different processes occurring in overlapping time scales: geometry relaxation in the excited state, internal conversion, photoisomerization, and fast and slow dissociation. The simulations, based on a semiempirical method, had a sufficiently long duration (10 ps) to encompass all of the above processes. We tested several variants of methods based on the quantum mechanical (QM) distributions of the nuclear coordinates
    Language English
    Publishing date 2023-04-18
    Publishing country United States
    Document type Journal Article
    ISSN 1549-9626
    ISSN (online) 1549-9626
    DOI 10.1021/acs.jctc.3c00024
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  6. Article ; Online: Correction to: Clinical staging of Anderson‑Fabry cardiomyopathy: an operative proposal.

    Del Franco, Annamaria / Iannaccone, Giulia / Meucci, Maria Chiara / Lillo, Rosa / Cappelli, Francesco / Zocchi, Chiara / Pieroni, Maurizio / Graziani, Francesca / Olivotto, Iacopo

    Heart failure reviews

    2024  Volume 29, Issue 2, Page(s) 571

    Language English
    Publishing date 2024-01-31
    Publishing country United States
    Document type Published Erratum
    ZDB-ID 1336499-6
    ISSN 1573-7322 ; 1382-4147
    ISSN (online) 1573-7322
    ISSN 1382-4147
    DOI 10.1007/s10741-023-10379-2
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    Zs.A 5212: Show issues Location:
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  7. Article ; Online: Il coinvolgimento cardiaco nella malattia di Fabry

    Maurizio Pieroni

    Giornale di Clinica Nefrologia e Dialisi, Vol 29, Iss Suppl.

    2017  Volume 1

    Abstract: Abstract non ... ...

    Abstract Abstract non disponibile
    Keywords Fabry disease ; Hypertrophic cardiomyopathy ; Left ventricular hypertrophy ; Internal medicine ; RC31-1245 ; Diseases of the genitourinary system. Urology ; RC870-923
    Language Italian
    Publishing date 2017-09-01T00:00:00Z
    Publisher AboutScience Srl
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article: Myocarditis and COVID-19 related issues.

    Ciabatti, Michele / Zocchi, Chiara / Olivotto, Iacopo / Bolognese, Leonardo / Pieroni, Maurizio

    Global cardiology science & practice

    2023  Volume 2023, Issue 4, Page(s) e202328

    Abstract: The recent COVID-19 (Coronavirus Disease 2019) pandemic by SARS-CoV2 infection has caused millions of deaths and hospitalizations across the globe. In the early pandemic phases, the infection had been initially considered a primary pulmonary disease. ... ...

    Abstract The recent COVID-19 (Coronavirus Disease 2019) pandemic by SARS-CoV2 infection has caused millions of deaths and hospitalizations across the globe. In the early pandemic phases, the infection had been initially considered a primary pulmonary disease. However, increasing evidence has demonstrated a wide range of possible cardiac involvement. Most of systemic and cardiac damage is likely sustained by a complex interplay between inflammatory, immune-related and thrombotic mechanisms. Biventricular failure and myocardial damage with elevation of cardiac biomarkers have been reported in COVID-19 patients, although histological demonstration of acute myocarditis has been rarely documented. Indeed while cardiac magnetic resonance findings include different patterns of myocardial involvement in terms of late gadolinium enhancement, histological data from necropsy and endomyocardial biopsy showed peculiar inflammatory patterns, mostly composed by macrophages. On the other hand COVID-19 vaccines based on mRN technology have been also associated with increased risk of myocarditis. COVID-19 and mRNA vaccine-related myocarditis present different clinical and imaging presentations and recent data suggest the presence of distinctive immunological mechanisms involved.
    Language English
    Publishing date 2023-09-30
    Publishing country Qatar
    Document type Journal Article ; Review
    ZDB-ID 2738381-7
    ISSN 2305-7823
    ISSN 2305-7823
    DOI 10.21542/gcsp.2023.28
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  9. Article ; Online: From Atrial Fibrillation Management to Atrial Myopathy Assessment: The Evolving Concept of Left Atrium Disease in Hypertrophic Cardiomyopathy.

    Fumagalli, Carlo / Zocchi, Chiara / Ciabatti, Michele / Milazzo, Alessandra / Cappelli, Francesco / Fumagalli, Stefano / Pieroni, Maurizio / Olivotto, Iacopo

    The Canadian journal of cardiology

    2024  

    Abstract: Hypertrophic cardiomyopathy (HCM) is the most prevalent genetically inherited cardiovascular disorder in adults and a significant cause of heart failure and sudden cardiac death. Historically, atrial fibrillation (AF) has been considered as a critical ... ...

    Abstract Hypertrophic cardiomyopathy (HCM) is the most prevalent genetically inherited cardiovascular disorder in adults and a significant cause of heart failure and sudden cardiac death. Historically, atrial fibrillation (AF) has been considered as a critical aspect in HCM patients as it is considered to be a marker of disease progression, escalates the frequency of heart failure hospitalisations, increases the risk of thromboembolic events, and worsens quality of life and outcome. Increasing evidence suggests that AF is the result of a subtle long-standing process that starts early in the history of HCM. The process of left atrial dilation accompanied by morphologic and functional remodelling is the quintessential prerequisite for the onset of AF. This review aims to describe the current understanding of AF pathophysiology in HCM, emphasising the role of left atrial myopathy in its development. In addition, we discuss risk factors and management strategies specific to AF in the context of HCM, providing insights into the complexities and challenges of treating this specific patient population.
    Language English
    Publishing date 2024-01-28
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 632813-1
    ISSN 1916-7075 ; 0828-282X
    ISSN (online) 1916-7075
    ISSN 0828-282X
    DOI 10.1016/j.cjca.2024.01.026
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    Zs.A 2150: Show issues Location:
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  10. Article ; Online: Multimodality Imaging Assessment and Follow-Up in a Case of Rickettsial Myocarditis: Echocardiographic and Cardiac Magnetic Resonance Features.

    Ciabatti, Michele / Pieroni, Maurizio / Felici, Massimo / Bolognese, Leonardo

    Circulation. Cardiovascular imaging

    2021  Volume 14, Issue 12, Page(s) 1151–1154

    MeSH term(s) Adult ; Echocardiography/methods ; Follow-Up Studies ; Humans ; Magnetic Resonance Imaging/methods ; Male ; Multimodal Imaging/methods ; Myocarditis/diagnostic imaging ; Myocarditis/etiology ; Myocarditis/physiopathology ; Rickettsia Infections/complications ; Rickettsia Infections/diagnostic imaging ; Rickettsia Infections/physiopathology ; Young Adult
    Language English
    Publishing date 2021-12-08
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2435045-X
    ISSN 1942-0080 ; 1941-9651
    ISSN (online) 1942-0080
    ISSN 1941-9651
    DOI 10.1161/CIRCIMAGING.121.013481
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