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Article: Understanding the Mechanism of Antimicrobial Resistance and Pathogenesis of

Khan, Maryam / Shamim, Saba

2022 Volume 10, Issue 10

Abstract: Salmonella ... ...

Abstract	Salmonella enterica
Language	English
Publishing date	2022-10-11
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2720891-6
ISSN	2076-2607
ISSN	2076-2607
DOI	10.3390/microorganisms10102006
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Anisi Stellati Fructus

Khan, Maryam / Shamim, Saba

Evidence-based complementary and alternative medicine : eCAM

2022 Volume 2022, Page(s) 4071489

Abstract: Anisi stellati ... ...

Abstract	Anisi stellati fructus
Language	English
Publishing date	2022-05-09
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	2171158-6
ISSN	1741-4288 ; 1741-427X
ISSN (online)	1741-4288
ISSN	1741-427X
DOI	10.1155/2022/4071489
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Anisi Stellati Fructus, a Significant Traditional Chinese Medicine (TCM) Herb and Its Bioactivity against Gastric Cancer

Maryam Khan / Saba Shamim

Evidence-Based Complementary and Alternative Medicine, Vol

2022 Volume 2022

Abstract: Anisi stellati fructus (ASF) is the fruit of Illicium verum Hook F. (Chinese star anise), which is native to many countries, and is a significant Chinese medicinal herb. Gastric cancer (GC) is one of the major fatal types of cancers with multiple stages ... ...

Abstract	Anisi stellati fructus (ASF) is the fruit of Illicium verum Hook F. (Chinese star anise), which is native to many countries, and is a significant Chinese medicinal herb. Gastric cancer (GC) is one of the major fatal types of cancers with multiple stages and a poor prognosis. The present review aims to discuss the bioactive properties of ASF and its phytocompounds against GC, with a particular insight into the molecular mechanisms and signaling pathways involved in its anti-GC mechanism. Furthermore, it highlights the potential mechanism of action of major phytocompounds of ASF against GC. Clinical studies (in vitro and in vivo) regarding the action of ASF and its major bioactive compounds such as quercetin, luteolin, kaempferol, d-limonene, and honokiol against GC were reviewed. For this review, search of literature was performed in Science, PubMed, Google Scholar, Web of Science, and Scopus related to ASF and its phytocompounds, from which only relevant studies were chosen. Major bioactive compounds of ASF and their extracts have proven to be effective against GC due to the mechanistic action of these compounds involving signaling pathways that target cancer cell apoptosis, proliferation, and tumor metastasis in GC cells. Existing reports of these compounds and their combinatory effects with other modern anticancer agents have also been reviewed. From its traditional use to its role as an anticancer agent, ASF and its bioactive phytocompounds have been observed to be effective in modern research, specifically against GC. However, further studies are required for the identification of molecular targets and pharmacokinetic potential and for the formulation of anti-GC drugs.
Keywords	Other systems of medicine ; RZ201-999
Subject code	500
Language	English
Publishing date	2022-01-01T00:00:00Z
Publisher	Hindawi Limited
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Investigation of the Antibacterial, Anti-Biofilm, and Antioxidative Effect of

Jalil, Varda / Khan, Maryam / Haider, Syed Zeeshan / Shamim, Saba

Microorganisms

2022 Volume 10, Issue 12

Abstract: Among oral diseases, dental caries is one of the most frequent to affect human health. The current research work aimed to ascertain the antibacterial, anti-biofilm, and antioxidative potential ... ...

Abstract	Among oral diseases, dental caries is one of the most frequent to affect human health. The current research work aimed to ascertain the antibacterial, anti-biofilm, and antioxidative potential of
Language	English
Publishing date	2022-12-15
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2720891-6
ISSN	2076-2607
ISSN	2076-2607
DOI	10.3390/microorganisms10122485
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Corrigendum: Zinc essentiality, toxicity, and its bacterial bioremediation: A comprehensive insight.

Hussain, Sarfraz / Khan, Maryam / Sheikh, Taha Majid Mahmood / Mumtaz, Muhammad Zahid / Chohan, Talha Ali / Shamim, Saba / Liu, Yuhong

Frontiers in microbiology

2023 Volume 13, Page(s) 1133733

Abstract: This corrects the article DOI: 10.3389/fmicb.2022.900740.]. ...

Abstract	[This corrects the article DOI: 10.3389/fmicb.2022.900740.].
Language	English
Publishing date	2023-01-17
Publishing country	Switzerland
Document type	Published Erratum
ZDB-ID	2587354-4
ISSN	1664-302X
ISSN	1664-302X
DOI	10.3389/fmicb.2022.1133733
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Article ; Online: Encyclopaedic Review of Glipizide Pre-clinical and Clinical Status.

Mohammad, Saad / Mahmood, Tarique / Shamim, Arshiya / Ahsan, Farogh / Shariq, Mohammad / Parveen, Saba / Waseem, Rufaida / Singh, Aditya

Drug research

2024 Volume 74, Issue 3, Page(s) 123–132

Abstract: Glipizide is an oral glucose-lowering medication that is beneficial for the treatment of type 2 diabetes. This study compiles exhaustively all accessible information on glipizide, from preclinical to clinical studies. Glipizide may be used in concert ... ...

Abstract	Glipizide is an oral glucose-lowering medication that is beneficial for the treatment of type 2 diabetes. This study compiles exhaustively all accessible information on glipizide, from preclinical to clinical studies. Glipizide may be used in concert with TRAIL to treat cancer cells; in vitro studies have shown that it suppresses angiogenesis and vasculogenesis while shielding cells from glycation-induced damage. Anticonvulsant effects and modifications in the pharmacokinetics of other medications, such as Divalproex Sodium, were seen in glipizide in vivo experiments. Propranolol amplifies glipizide's hypoglycemic effect briefly in normal animals but consistently enhances it in diabetic ones. In the treatment of cancer and neurodegenerative poly(Q) illnesses, glipizide has demonstrated to offer potential therapeutic advantages. It is ineffective in preventing DENA-induced liver cancer and may cause DNA damage over time. The way glipizide interacts with genetic variants may increase the risk of hypoglycemia. Combining Syzygium cumini and ARBE to glipizide may enhance glycemic and lipid control in type 2 diabetes. Individuals with coronary artery disease who take glipizide or glyburide have an increased risk of death. The risk of muscular responses and acute pancreatitis is minimal when glipizide and dulaglutide are combined. In conclusion, glipizide has shown promising therapeutic efficacy across a variety of disorders.
MeSH term(s)	Humans ; Glipizide/adverse effects ; Diabetes Mellitus, Type 2/drug therapy ; Diabetes Mellitus, Type 2/chemically induced ; Acute Disease ; Blood Glucose ; Pancreatitis/chemically induced ; Pancreatitis/drug therapy
Chemical Substances	Glipizide (X7WDT95N5C) ; Blood Glucose
Language	English
Publishing date	2024-02-26
Publishing country	Germany
Document type	Journal Article
ZDB-ID	2703847-6
ISSN	2194-9387 ; 2194-9379
ISSN (online)	2194-9387
ISSN	2194-9379
DOI	10.1055/a-2237-8566
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Article: Unraveling the Underlying Heavy Metal Detoxification Mechanisms of

Alotaibi, Badriyah Shadid / Khan, Maryam / Shamim, Saba

Microorganisms

2021 Volume 9, Issue 8

Abstract: The rise of anthropogenic activities has resulted in the increasing release of various contaminants into the environment, jeopardizing fragile ecosystems in the process. Heavy metals are one of the major pollutants that contribute to the escalating ... ...

Abstract	The rise of anthropogenic activities has resulted in the increasing release of various contaminants into the environment, jeopardizing fragile ecosystems in the process. Heavy metals are one of the major pollutants that contribute to the escalating problem of environmental pollution, being primarily introduced in sensitive ecological habitats through industrial effluents, wastewater, as well as sewage of various industries. Where heavy metals like zinc, copper, manganese, and nickel serve key roles in regulating different biological processes in living systems, many heavy metals can be toxic even at low concentrations, such as mercury, arsenic, cadmium, chromium, and lead, and can accumulate in intricate food chains resulting in health concerns. Over the years, many physical and chemical methods of heavy metal removal have essentially been investigated, but their disadvantages like the generation of chemical waste, complex downstream processing, and the uneconomical cost of both methods, have rendered them inefficient,. Since then, microbial bioremediation, particularly the use of bacteria, has gained attention due to the feasibility and efficiency of using them in removing heavy metals from contaminated environments. Bacteria have several methods of processing heavy metals through general resistance mechanisms, biosorption, adsorption, and efflux mechanisms.
Language	English
Publishing date	2021-07-30
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2720891-6
ISSN	2076-2607
ISSN	2076-2607
DOI	10.3390/microorganisms9081628
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Article ; Online: Continuing professional development for pharmacists in three countries with developing health systems.

Shamim, Saba / Rasheed, Huma / Babar, Zaheer-Ud-Din

Currents in pharmacy teaching & learning

2021 Volume 13, Issue 5, Page(s) 471–478

Abstract: Introduction: The role of pharmacists in healthcare is undergoing transformation throughout the world. The continuing professional development (CPD) model has motivated pharmacists in developed countries to adopt lifelong learning. This is vital to ... ...

Abstract	Introduction: The role of pharmacists in healthcare is undergoing transformation throughout the world. The continuing professional development (CPD) model has motivated pharmacists in developed countries to adopt lifelong learning. This is vital to improve competence and to optimize patient care. This study aimed to explore the existence and understanding of CPD in Ghana, Pakistan, and Trinidad and Tobago, the barriers faced in development of a CPD model, and probable policies needed to build/improve such a model. Methods: Audiotaped qualitative in-depth interviews were conducted, transcribed, and coded with pharmacy stakeholders, including academics, community pharmacists, and regulatory professionals. A thematic analysis of the transcribed data led to the extraction of the main themes. Results: The findings showed a process of establishment of CPD for pharmacists in Ghana, whereas in Pakistan, Trinidad, and Tobago there was no CPD model. Conclusions: These findings indicate the need for a realistic, relevant, and mandatory program of CPD in these countries.
MeSH term(s)	Education, Pharmacy, Continuing ; Humans ; Learning ; Pharmaceutical Services ; Pharmacies ; Pharmacists
Language	English
Publishing date	2021-02-03
Publishing country	United States
Document type	Journal Article
ZDB-ID	2515217-8
ISSN	1877-1300 ; 1877-1297
ISSN (online)	1877-1300
ISSN	1877-1297
DOI	10.1016/j.cptl.2021.01.002
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Emerging Trends of Multidrug-Resistant (MDR) and Extensively Drug-Resistant (XDR)

Zakir, Muhammad / Khan, Maryam / Umar, Muhammad Ihtisham / Murtaza, Ghulam / Ashraf, Muhammad / Shamim, Saba

Microorganisms

2021 Volume 9, Issue 12

Abstract: ... ...

Abstract	Salmonella
Language	English
Publishing date	2021-11-30
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2720891-6
ISSN	2076-2607
ISSN	2076-2607
DOI	10.3390/microorganisms9122484
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Unraveling the Underlying Heavy Metal Detoxification Mechanisms of Bacillus Species

Badriyah Shadid Alotaibi / Maryam Khan / Saba Shamim

Microorganisms, Vol 9, Iss 1628, p

2021 Volume 1628

Abstract	The rise of anthropogenic activities has resulted in the increasing release of various contaminants into the environment, jeopardizing fragile ecosystems in the process. Heavy metals are one of the major pollutants that contribute to the escalating problem of environmental pollution, being primarily introduced in sensitive ecological habitats through industrial effluents, wastewater, as well as sewage of various industries. Where heavy metals like zinc, copper, manganese, and nickel serve key roles in regulating different biological processes in living systems, many heavy metals can be toxic even at low concentrations, such as mercury, arsenic, cadmium, chromium, and lead, and can accumulate in intricate food chains resulting in health concerns. Over the years, many physical and chemical methods of heavy metal removal have essentially been investigated, but their disadvantages like the generation of chemical waste, complex downstream processing, and the uneconomical cost of both methods, have rendered them inefficient,. Since then, microbial bioremediation, particularly the use of bacteria, has gained attention due to the feasibility and efficiency of using them in removing heavy metals from contaminated environments. Bacteria have several methods of processing heavy metals through general resistance mechanisms, biosorption, adsorption, and efflux mechanisms. Bacillus spp. are model Gram-positive bacteria that have been studied extensively for their biosorption abilities and molecular mechanisms that enable their survival as well as their ability to remove and detoxify heavy metals. This review aims to highlight the molecular methods of Bacillus spp. in removing various heavy metals ions from contaminated environments.
Keywords	bioremediation ; Bacillus ; resistance ; microorganisms ; biosorption ; efflux ; Biology (General) ; QH301-705.5
Language	English
Publishing date	2021-07-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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