LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 293

Search options

  1. Article: Hip, knee, and shoulder arthroplasty in patients with a history of solid organ transplant: A review.

    Patel, Akshar V / Stevens, Andrew J / White, Ryan / Aravindan, Shreyaas / Barry, Louis W / Rauck, Ryan C

    Journal of orthopaedics

    2024  Volume 51, Page(s) 116–121

    Abstract: Solid organ transplants (SOT) have evolved into life-saving interventions for end-stage diseases affecting vital organs. Advances in transplantation techniques, donor selection, and immunosuppressive therapies have enhanced outcomes, leading to a growing ...

    Abstract Solid organ transplants (SOT) have evolved into life-saving interventions for end-stage diseases affecting vital organs. Advances in transplantation techniques, donor selection, and immunosuppressive therapies have enhanced outcomes, leading to a growing demand for SOT. Patients with a solid organ transplant are living long enough to develop the same pathologies which are indicated for joint replacement surgery in the general population. SOT patients who undergo a total hip, knee, or shoulder arthroplasty do similarly in the context of clinical outcomes and implant survival when compared to the general population. These immunosuppressed patients tend to have higher complication rates in the short-term following surgery. Prudent management of these patients in the short-term may be necessary, but patients can expect to do well otherwise.
    Language English
    Publishing date 2024-02-05
    Publishing country India
    Document type Journal Article ; Review
    ZDB-ID 2240839-3
    ISSN 0972-978X
    ISSN 0972-978X
    DOI 10.1016/j.jor.2024.02.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article: Paediatric Thoracic Imaging in Cystic Fibrosis in the Era of Cystic Fibrosis Transmembrane Conductance Regulator Modulation.

    O'Regan, Patrick W / Stevens, Niamh E / Logan, Niamh / Ryan, David J / Maher, Michael M

    Children (Basel, Switzerland)

    2024  Volume 11, Issue 2

    Abstract: Cystic fibrosis (CF) is one of the most common progressive life-shortening genetic conditions worldwide. Ground-breaking translational research has generated therapies that target the primary cystic fibrosis transmembrane conductance regulator (CFTR) ... ...

    Abstract Cystic fibrosis (CF) is one of the most common progressive life-shortening genetic conditions worldwide. Ground-breaking translational research has generated therapies that target the primary cystic fibrosis transmembrane conductance regulator (CFTR) defect, known as CFTR modulators. A crucial aspect of paediatric CF disease is the development and progression of irreversible respiratory disease in the absence of clinical symptoms. Accurate thoracic diagnostics have an important role to play in this regard. Chest radiographs are non-specific and insensitive in the context of subtle changes in early CF disease, with computed tomography (CT) providing increased sensitivity. Recent advancements in imaging hardware and software have allowed thoracic CTs to be acquired in paediatric patients at radiation doses approaching that of a chest radiograph. CFTR modulators slow the progression of CF, reduce the frequency of exacerbations and extend life expectancy. In conjunction with advances in CT imaging techniques, low-dose thorax CT will establish a central position in the routine care of children with CF. International guidelines regarding the choice of modality and timing of thoracic imaging in children with CF are lagging behind these rapid technological advances. The continued progress of personalised medicine in the form of CFTR modulators will promote the emergence of personalised radiological diagnostics.
    Language English
    Publishing date 2024-02-16
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2732685-8
    ISSN 2227-9067
    ISSN 2227-9067
    DOI 10.3390/children11020256
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article ; Online: A Broad Spectrum of Possibilities: Spectrum Scores as a Unifying Metric of Antibiotic Utilization.

    Ilges, Dan / Tande, Aaron J / Stevens, Ryan W

    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

    2023  Volume 77, Issue 2, Page(s) 167–173

    Abstract: Days of therapy (DOT) currently serve as the standard antimicrobial utilization metric. However, by assigning the same weight to each agent rather than accounting for differences in spectrum of activity, DOT ignore key differences between agents that are ...

    Abstract Days of therapy (DOT) currently serve as the standard antimicrobial utilization metric. However, by assigning the same weight to each agent rather than accounting for differences in spectrum of activity, DOT ignore key differences between agents that are fundamental to infectious diseases and critical to antimicrobial stewardship. Spectrum scoring assigns numeric values to individual antibiotic agents to quantify their spectrum of activity, allowing for the normalization of antibiotic utilization data. When used in conjunction with traditional metrics, spectrum scores may offer further clarity to antibiotic utilization; however, issues related to development, application, and standardization of spectrum scores remain. Despite these challenges, the potential applications of spectrum scores are vast. Here, we summarize existing data and explore the future of spectrum scoring, including application to both data analysis and routine patient care, use in inpatient and outpatient settings, integration within the electronic medical record, and opportunities for future research.
    MeSH term(s) Humans ; Anti-Bacterial Agents/therapeutic use ; Drug Utilization ; Communicable Diseases/drug therapy ; Anti-Infective Agents ; Antimicrobial Stewardship
    Chemical Substances Anti-Bacterial Agents ; Anti-Infective Agents
    Language English
    Publishing date 2023-03-30
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1099781-7
    ISSN 1537-6591 ; 1058-4838
    ISSN (online) 1537-6591
    ISSN 1058-4838
    DOI 10.1093/cid/ciad189
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article ; Online: An inconspicuous identification: Isolation and identification of a novel Pichia species presenting as fungemia following cardiac surgery.

    Caldwell, Allorie T / Gabaldón, Toni / Mixão, Verónica / Wengenack, Nancy L / Westley, Benjamin P / Stevens, Ryan W

    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases

    2024  Volume 143, Page(s) 107040

    Abstract: Fungemia is common in critically ill patient populations, and is associated with a high rate of mortality, especially when caused by nonalbicans Candida species. Herein, we describe a fatal case of fungemia following cardiothoracic surgery in which the ... ...

    Abstract Fungemia is common in critically ill patient populations, and is associated with a high rate of mortality, especially when caused by nonalbicans Candida species. Herein, we describe a fatal case of fungemia following cardiothoracic surgery in which the organism, initially identified as Candida inconspicua, represents a novel species: Pichia alaskaensis.
    Language English
    Publishing date 2024-04-04
    Publishing country Canada
    Document type Case Reports
    ZDB-ID 1331197-9
    ISSN 1878-3511 ; 1201-9712
    ISSN (online) 1878-3511
    ISSN 1201-9712
    DOI 10.1016/j.ijid.2024.107040
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Article: Correction: Adema et al. Heartbreaking Decisions: The Dogma and Uncertainties of Antimicrobial Therapy in Infective Endocarditis.

    Adema, Jennifer L / Ahiskali, Aileen / Fida, Madiha / Mediwala Hornback, Krutika / Stevens, Ryan W / Rivera, Christina G

    Pathogens (Basel, Switzerland)

    2024  Volume 13, Issue 3

    Abstract: There was an error in the original publication [ ... ]. ...

    Abstract There was an error in the original publication [...].
    Language English
    Publishing date 2024-02-21
    Publishing country Switzerland
    Document type Published Erratum
    ZDB-ID 2695572-6
    ISSN 2076-0817
    ISSN 2076-0817
    DOI 10.3390/pathogens13030190
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  6. Article: Native mitral valve infective endocarditis due to

    Schanz, Caitlin C / Layden, Mark P / DeSimone, Daniel C / Stevens, Ryan W / Clement, Josh

    IDCases

    2023  Volume 33, Page(s) e01818

    Abstract: Dolosigranulum ... ...

    Abstract Dolosigranulum pigrum
    Language English
    Publishing date 2023-06-12
    Publishing country Netherlands
    Document type Case Reports
    ZDB-ID 2745454-X
    ISSN 2214-2509
    ISSN 2214-2509
    DOI 10.1016/j.idcr.2023.e01818
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  7. Article ; Online: Cracking the code(s): Optimization of encounter-level diagnosis coding to inform outpatient antimicrobial stewardship data modeling.

    Stevens, Ryan W / Manz, James / Mathre, Margo / Bell, Natalie / Virk, Abinash / Vergidis, Paschalis / Jensen, Kelsey

    Infection control and hospital epidemiology

    2024  Volume 45, Issue 4, Page(s) 550–552

    MeSH term(s) Humans ; Outpatients ; Antimicrobial Stewardship ; Anti-Bacterial Agents/therapeutic use
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2024-01-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 639378-0
    ISSN 1559-6834 ; 0195-9417 ; 0899-823X
    ISSN (online) 1559-6834
    ISSN 0195-9417 ; 0899-823X
    DOI 10.1017/ice.2023.296
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  8. Article ; Online: Antimicrobial susceptibilities of

    Zhang, Ming May / Melton, Tanner A / Akhtar, Haris / Shah, Aditya / Schuetz, Audrey N / Clement, Josh / Stevens, Ryan W

    Journal of clinical microbiology

    2024  Volume 62, Issue 4, Page(s) e0144723

    Abstract: Campylobacter fetus: Importance: Our findings contribute to the scant literature ... ...

    Abstract Campylobacter fetus
    Importance: Our findings contribute to the scant literature on
    MeSH term(s) Humans ; Aged ; Campylobacter fetus ; Doxycycline/pharmacology ; Meropenem ; Agar ; Anti-Bacterial Agents/pharmacology ; Ciprofloxacin/pharmacology ; Erythromycin/pharmacology ; Tetracycline ; Anti-Infective Agents ; Gentamicins/pharmacology ; Microbial Sensitivity Tests ; Campylobacter
    Chemical Substances Doxycycline (N12000U13O) ; Meropenem (FV9J3JU8B1) ; Agar (9002-18-0) ; Anti-Bacterial Agents ; Ciprofloxacin (5E8K9I0O4U) ; Erythromycin (63937KV33D) ; Tetracycline (F8VB5M810T) ; Anti-Infective Agents ; Gentamicins
    Language English
    Publishing date 2024-02-29
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 390499-4
    ISSN 1098-660X ; 0095-1137
    ISSN (online) 1098-660X
    ISSN 0095-1137
    DOI 10.1128/jcm.01447-23
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  9. Article: Sequential Time to Positivity as a Prognostic Indicator in

    Comba, Isin Y / Go, John Raymond / Vaillant, James / O'Horo, John C / Stevens, Ryan W / Palraj, Raj / Abu Saleh, Omar

    Open forum infectious diseases

    2024  Volume 11, Issue 4, Page(s) ofae173

    Abstract: Background: We aimed to determine the factors associated with sequential blood culture time to positivity (STTP) and validate the previously defined time to positivity (TTP) ratio threshold of 1.5 in predicting adverse disease outcomes and mortality of ! ...

    Abstract Background: We aimed to determine the factors associated with sequential blood culture time to positivity (STTP) and validate the previously defined time to positivity (TTP) ratio threshold of 1.5 in predicting adverse disease outcomes and mortality of
    Methods: We conducted an observational study of adult patients with SAB. The TTP ratio was calculated by dividing the TTP of the second blood culture by that of the first.
    Results: Of 186 patients, 69 (37%) were female, with a mean age of 63.6 years. Median TTP was 12 hours (interquartile range [IQR], 10-15 hours) from the initial and 21 hours (17-29) from sequential blood cultures. Methicillin-resistant
    Conclusions: The STTP varies based on methicillin susceptibility of
    Language English
    Publishing date 2024-03-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2757767-3
    ISSN 2328-8957
    ISSN 2328-8957
    DOI 10.1093/ofid/ofae173
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  10. Article ; Online: Therapeutic drug monitoring following crushed administration of delayed-release posaconazole tablets via enteral feeding tubes.

    Stevens, Ryan W / O'Connell, Casey / Huang, Angie / Epps, Kevin L / Ilges, Dan

    The Journal of antimicrobial chemotherapy

    2022  Volume 78, Issue 2, Page(s) 553–555

    MeSH term(s) Enteral Nutrition ; Drug Monitoring ; Triazoles ; Administration, Oral ; Tablets
    Chemical Substances posaconazole (6TK1G07BHZ) ; Triazoles ; Tablets
    Language English
    Publishing date 2022-12-21
    Publishing country England
    Document type Journal Article
    ZDB-ID 191709-2
    ISSN 1460-2091 ; 0305-7453
    ISSN (online) 1460-2091
    ISSN 0305-7453
    DOI 10.1093/jac/dkac427
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top