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  1. Article ; Online: Efficacy and safety of prophylactic anticoagulation in patients with primary nephrotic syndrome: a systematic review and meta-analysis.

    De Pascali, Federica / Brunini, Francesca / Rombolà, Giuseppe / Squizzato, Alessandro

    Internal medicine journal

    2023  Volume 54, Issue 2, Page(s) 214–223

    Abstract: Background and aims: Nephrotic syndrome (NS) is associated with an increased incidence of venous thromboembolism (VTE), approximately 10%. We performed a systematic review to evaluate the efficacy and safety of prophylactic anticoagulation in patients ... ...

    Abstract Background and aims: Nephrotic syndrome (NS) is associated with an increased incidence of venous thromboembolism (VTE), approximately 10%. We performed a systematic review to evaluate the efficacy and safety of prophylactic anticoagulation in patients with NS.
    Methods: Studies evaluating prophylactic anticoagulation in NS were identified by an electronic search of MEDLINE and EMBASE databases until December 2021. Weighted mean proportion and 95% confidence intervals (CIs) of thromboembolic and haemorrhagic events were calculated using a fixed-effects and a random-effects model. The differences in the outcomes among groups were estimated as pooled odds ratio (OR) and corresponding 95% CI. Statistical heterogeneity was evaluated using the I
    Results: Five cohort studies, for a total of 414 adult patients, were included. Only two studies had a control group. The weighted mean incidence of pulmonary embolism (PE) and deep vein thrombosis in patients who received VTE prophylaxis was 1.8% (95% CI: 0.6-3.5%; I
    Conclusions: Our findings suggest that prophylactic anticoagulation in adult patients with primary NS may reduce the risk of VTE, even if it may be associated with a not negligible bleeding risk.
    MeSH term(s) Adult ; Humans ; Anticoagulants/adverse effects ; Venous Thromboembolism/epidemiology ; Venous Thromboembolism/prevention & control ; Venous Thromboembolism/etiology ; Nephrotic Syndrome/complications ; Nephrotic Syndrome/drug therapy ; Nephrotic Syndrome/chemically induced ; Pulmonary Embolism/epidemiology ; Hemorrhage/chemically induced ; Hemorrhage/epidemiology
    Chemical Substances Anticoagulants
    Language English
    Publishing date 2023-09-15
    Publishing country Australia
    Document type Meta-Analysis ; Systematic Review ; Journal Article ; Review
    ZDB-ID 2045436-3
    ISSN 1445-5994 ; 1444-0903
    ISSN (online) 1445-5994
    ISSN 1444-0903
    DOI 10.1111/imj.16227
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 792: Show issues Location:
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  2. Article ; Online: Can the response to dialysis treatment be predicted by using patient-specific modeling of fluid and solute exchanges? A multicentric evaluation.

    Balsamello, Carlo / Rombolà, Giuseppe / Costantino, Maria Laura / Casagrande, Giustina

    Artificial organs

    2023  Volume 47, Issue 8, Page(s) 1326–1341

    Abstract: Background: Parametric multipool kinetic models were used to describe the intradialytic trends of electrolytes, breakdown products, and body fluids volumes during hemodialysis. Therapy customization can be achieved by the identification of parameters, ... ...

    Abstract Background: Parametric multipool kinetic models were used to describe the intradialytic trends of electrolytes, breakdown products, and body fluids volumes during hemodialysis. Therapy customization can be achieved by the identification of parameters, allowing patient-specific modulation of mass and fluid balance across dialyzer, capillary, and cell membranes. This study wants to evaluate the possibility to use this approach to predict the patient's intradialytic response.
    Methods: 6 sessions of 68 patients (DialysIS© project) were considered. Data from the first three sessions were used to train the model, identifying the patient-specific parameters, that, together with the treatment settings and the patient's data at the session start, could be used for predicting the patient's specific time course of solutes and fluids along the sessions. Na
    Results: nRMSE predictive error is on average equal to 4.76% when describing the training sessions, and only increases by 0.97 percentage points on average in independent sessions of the same patient.
    Conclusions: The proposed predictive approach represents a first step in the development of tools to support the clinician in tailoring the patient's prescription.
    MeSH term(s) Humans ; Renal Dialysis ; Patient-Specific Modeling ; Water-Electrolyte Balance ; Sodium
    Chemical Substances Sodium (9NEZ333N27)
    Language English
    Publishing date 2023-04-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 441812-8
    ISSN 1525-1594 ; 0160-564X
    ISSN (online) 1525-1594
    ISSN 0160-564X
    DOI 10.1111/aor.14530
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    Zs.A 1463: Show issues Location:
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  3. Article ; Online: Il Ruolo Centrale Dell'infermiere Nella Gestione Degli Accessi Vascolari per la Dialisi in un Team Multidisciplinare

    Giuseppe Rombolà

    Giornale di Clinica Nefrologia e Dialisi, Vol 29, Iss

    2017  Volume 2

    Abstract: Abstract non ... ...

    Abstract Abstract non disponibile
    Keywords Internal medicine ; RC31-1245 ; Diseases of the genitourinary system. Urology ; RC870-923
    Language Italian
    Publishing date 2017-05-01T00:00:00Z
    Publisher AboutScience Srl
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: COVID-19 and dialysis: why we should be worried.

    Rombolà, Giuseppe / Brunini, Francesca

    Journal of nephrology

    2020  Volume 33, Issue 3, Page(s) 401–403

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections/complications ; Coronavirus Infections/epidemiology ; Coronavirus Infections/mortality ; Disease Transmission, Infectious/prevention & control ; Humans ; Infection Control/methods ; Kidney Failure, Chronic/complications ; Kidney Failure, Chronic/therapy ; Pandemics/statistics & numerical data ; Pneumonia, Viral/complications ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/mortality ; Prevalence ; Renal Dialysis/adverse effects ; Renal Dialysis/statistics & numerical data ; SARS-CoV-2 ; Universal Precautions
    Keywords covid19
    Language English
    Publishing date 2020-04-22
    Publishing country Italy
    Document type Editorial
    ZDB-ID 1093991-x
    ISSN 1724-6059 ; 1120-3625 ; 1121-8428
    ISSN (online) 1724-6059
    ISSN 1120-3625 ; 1121-8428
    DOI 10.1007/s40620-020-00737-w
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    Zs.A 3369: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  5. Article ; Online: Sanità: è possibile ridurre i costi e migliorare le cure.

    Rombolà, Giuseppe

    Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia

    2013  Volume 30, Issue 2

    Title translation Health care: the possible cost reduction and improvement of care.
    MeSH term(s) Cost Savings ; Delivery of Health Care ; Economic Recession ; Economics ; European Union ; Forecasting ; Health Care Costs ; Health Care Reform ; Health Resources/economics ; Health Resources/utilization ; Home Care Services ; Humans ; Italy ; Medical Tourism ; Quality Assurance, Health Care ; Quality Improvement ; Work Simplification ; World Health Organization
    Language Italian
    Publishing date 2013-03
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 1237110-5
    ISSN 1724-5990 ; 0393-5590
    ISSN (online) 1724-5990
    ISSN 0393-5590
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    Zs.A 4313: Show issues Location:
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  7. Article ; Online: COVID-19 and dialysis

    Rombolà, Giuseppe / Brunini, Francesca

    Journal of Nephrology

    why we should be worried

    2020  Volume 33, Issue 3, Page(s) 401–403

    Keywords Nephrology ; covid19
    Language English
    Publisher Springer Science and Business Media LLC
    Publishing country us
    Document type Article ; Online
    ZDB-ID 1093991-x
    ISSN 1724-6059 ; 1120-3625 ; 1121-8428
    ISSN (online) 1724-6059
    ISSN 1120-3625 ; 1121-8428
    DOI 10.1007/s40620-020-00737-w
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3369: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  8. Article ; Online: SARS-CoV-2 and Hemodialysis: diffusion and mortality in patients and health care team. Reflections from the Lombardy experience.

    Rombolà, Giuseppe / Heidempergher, Marco / Cornacchiari, Marina / Baragetti, Ivano / Pieruzzi, Federico

    Journal of nephrology

    2021  Volume 34, Issue 2, Page(s) 277–279

    MeSH term(s) COVID-19/epidemiology ; Comorbidity ; Humans ; Italy/epidemiology ; Kidney Failure, Chronic/epidemiology ; Kidney Failure, Chronic/therapy ; Pandemics ; Patient Care Team/statistics & numerical data ; Renal Dialysis ; SARS-CoV-2 ; Survival Rate/trends
    Language English
    Publishing date 2021-03-01
    Publishing country Italy
    Document type Editorial
    ZDB-ID 1093991-x
    ISSN 1724-6059 ; 1120-3625 ; 1121-8428
    ISSN (online) 1724-6059
    ISSN 1120-3625 ; 1121-8428
    DOI 10.1007/s40620-021-01003-3
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    Zs.A 3369: Show issues Location:
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  9. Article ; Online: The Use of POSS-Based Nanoadditives for Cable-Grade PVC: Effects on its Thermal Stability.

    Palin, Luca / Rombolà, Giuseppe / Milanesio, Marco / Boccaleri, Enrico

    Polymers

    2019  Volume 11, Issue 7

    Abstract: Plasticized-Poly(vinyl chloride) (P-PVC) for cables and insulation requires performances related to outdoor, indoor and submarine contexts and reduction of noxious release of HCl-containing fumes in case of thermal degradation or fire. Introducing ... ...

    Abstract Plasticized-Poly(vinyl chloride) (P-PVC) for cables and insulation requires performances related to outdoor, indoor and submarine contexts and reduction of noxious release of HCl-containing fumes in case of thermal degradation or fire. Introducing suitable nanomaterials in polymer-based nanocomposites can be an answer to this clue. In this work, an industry-compliant cable-grade P-PVC formulation was added with nanostructured materials belonging to the family of Polyhedral Oligomeric Silsesquioxane (POSS). The effects of the nanomaterials, alone and in synergy with HCl scavenging agents as zeolites and hydrotalcites, on the thermal stability and HCl evolution of P-PVC were deeply investigated by thermogravimetric analysis and reference ASTM methods. Moreover, hardness and mechanical properties were studied in order to highlight the effects of these additives in the perspective of final industrial uses. The data demonstrated relevant improvements in the thermal stability of the samples added with nanomaterials, already with concentrations of POSS down to 0.31 phr and interesting additive effects of POSS with zeolites and hydrotalcites for HCl release reduction without losing mechanical performances.
    Language English
    Publishing date 2019-06-29
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527146-5
    ISSN 2073-4360 ; 2073-4360
    ISSN (online) 2073-4360
    ISSN 2073-4360
    DOI 10.3390/polym11071105
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  10. Article ; Online: Low-Cost Biobased Coatings for AM60 Magnesium Alloys for Food Contact and Harsh Environment Applications.

    Mangolini, Beatrice / Lopresti, Mattia / Conterosito, Eleonora / Rombolà, Giuseppe / Palin, Luca / Gianotti, Valentina / Milanesio, Marco

    International journal of molecular sciences

    2021  Volume 22, Issue 9

    Abstract: Low-cost, environmentally friendly and easily applicable coating for Mg alloys, able to resist in real world conditions, are studied. Coatings already used for other metals (aluminum, steel) and never tested on Mg alloy for its different surface and ... ...

    Abstract Low-cost, environmentally friendly and easily applicable coating for Mg alloys, able to resist in real world conditions, are studied. Coatings already used for other metals (aluminum, steel) and never tested on Mg alloy for its different surface and reactivity were deposited on AM60 magnesium alloys to facilitate their technological applications, also in presence of chemically aggressive conditions. A biobased PA11 powder coating was compared to synthetic silicon-based and polyester coatings, producing lab scale samples, probed by drop deposition tests and dipping in increasingly aggressive, salty, basic and acid solutions, at RT and at higher temperatures. Coatings were analyzed by SEM/EDX to assess their morphology and compositions, by optical and IR-ATR microscopy analyses, before and after the drop tests. Migration analyses from the samples were performed by immersion tests using food simulants followed by ICP-OES analysis of the recovered simulant to explore applications also in the food contact field. A 30 μm thick white lacquer and a 120 μm PA11 coating resulted the best solutions. The thinner siliconic and lacquer coatings, appearing brittle and thin in the SEM analysis, failed some drop and/or dipping test, with damages especially at the edges. The larger thickness is thus the unique solution for edgy or pointy samples. Finally, coffee cups in AM60 alloy were produced, as real word prototypes, with the best performing coatings and tested for both migration by dipping, simulating also real world aging (2 h in acetic acid at 70° and 24 h in hot coffee at 60 °C): PA11 resulted stable in all the tests and no migration of toxic metals was observed, resulting a promising candidate for many real world application in chemically aggressive environments and also food and beverage related applications.
    MeSH term(s) Alloys/chemistry ; Alloys/economics ; Coated Materials, Biocompatible/chemistry ; Coated Materials, Biocompatible/economics ; Costs and Cost Analysis ; Environment ; Food ; Magnesium/chemistry ; Magnesium/economics ; Spectroscopy, Fourier Transform Infrared
    Chemical Substances Alloys ; Coated Materials, Biocompatible ; Magnesium (I38ZP9992A)
    Language English
    Publishing date 2021-05-06
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms22094915
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